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Form 8-K

sec.gov

8-K — Ensysce Biosciences, Inc.

Accession: 0001493152-26-044802

Filed: 2026-09-29

Period: 2026-09-25

CIK: 0001716947

SIC: 2834 (PHARMACEUTICAL PREPARATIONS)

Item: Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year

Item: Financial Statements and Exhibits

Documents

8-K — form8-k.htm (Primary)

EX-3 (ex-3.htm)

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UNITED

STATES

SECURITIES

AND EXCHANGE COMMISSION

WASHINGTON,

D.C. 20549

FORM

8-K

CURRENT

REPORT

Pursuant

to Section 13 or 15(d)

of

the Securities Exchange Act of 1934

Date

of Report (Date of earliest event reported): September 25, 2026

Ensysce

Biosciences, Inc.

(Exact

name of registrant as specified in its charter)

Delaware

001-38306

82-2755287

(State

or other jurisdiction

of

incorporation or organization)

(Commission

File

Number)

(I.R.S.

Employer

Identification

Number)

7946

Ivanhoe Avenue, Suite 201

La

Jolla, California

92037

(Address

of principal executive offices)

(Zip

Code)

(858)

263-4196

Registrant’s

telephone number, including area code

N/A

(Former

name or former address, if changed since last report)

Check

the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation to the registrant under

any of the following provisions:

☐

Written

communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

☐

Soliciting

material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

☐

Pre-commencement

communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

☐

Pre-commencement

communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities

registered pursuant to Section 12(b) of the Act:

Title

of each class

Trading

Symbol(s)

Name

of each exchange on which registered

Common

Stock, par value $0.0001 per share

ENSC

The

Nasdaq Stock Market LLC

Emerging

growth company ☐

If

an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying

with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

Item

5.03.

Amendments

to Articles of Incorporation or Bylaws; Change in Fiscal Year.

Certificate

of Amendment

On

August 5, 2026, Ensysce Biosciences, Inc., a Delaware corporation (“we,” “us,” “our,” or the “Company”),

filed

a Certificate of Designation of Preferences, Rights and Limitations of the Series C Non-Voting Convertible Preferred Stock (the “Series

C Certificate of Designation”) with the Secretary of State of the State of Delaware that related to the issuance of the Company’s

Series C Non-Voting Convertible Preferred Stock, par value $0.0001 per share (the “Series C Preferred Stock”). On August

6, 2026, we filed a Certificate of Correction to the Series C Certificate of Designation.

On

September 25, 2026, the Company amended the Series C Certificate of Designation to remove Section 6.5.3 and other references to Section

6.5.3 in the Series C Certificate of Designation (the “Amendment”). Section 6.5.3 provides that the Series C Preferred Stock

is redeemable for cash at the option of the holder thereof at any time following stockholder approval of the conversion of shares of

Series C Preferred Stock into shares of the Company’s common stock, par value $0.0001 per share (the “Common Stock”)

in accordance with the rules of the Nasdaq Stock Market LLC, if there is any failure to deliver shares of Common Stock in accordance

with the terms of the Series C Preferred Stock, at a price per share equal to the then-current fair value of the Series C Preferred Stock,

as described in the Series C Certificate of Designation. The Amendment was effective upon filing.

The

foregoing description of the Amendment does not purport to be complete and is qualified in its entirety by reference to the full text

of the Amendment, a copy of which is filed as Exhibit 3 to this Current Report and is incorporated herein by reference.

Item

9.01

Financial

Statements and Exhibits.

(d)

Exhibits

Exhibit

Number

Description

3

Certificate of Amendment, dated September 25, 2026, to the Certificate of Designation of Series C Non-Voting Convertible Preferred Stock of Ensysce Biosciences, Inc., dated August 5, 2026.

104

Cover

Page Interactive Data File (embedded within the Inline XBRL document).

SIGNATURE

Pursuant

to the requirements of the Securities Exchange Act of 1934, as amended, the registrant has duly caused this report to be signed on its

behalf by the undersigned hereunto duly authorized.

Dated:

September 29, 2026

Ensysce

Biosciences, Inc.

By:

/s/

Lynn Kirkpatrick

Name:

Dr.

Lynn Kirkpatrick

Title:

Chief

Executive Officer

(Principal

Executive Officer)

EX-3

EX-3

Filename: ex-3.htm · Sequence: 2

Exhibt

3

EnSYSCE

BIOSCIENCES, INC.

Certificate

of Amendment

to

Certificate

of designation OF PREFERENCES,

RIGHTS

AND LIMITATIONS

of

series

C NON-VOTING CONVERTIBLE PREFerred stock

Ensysce

Biosciences, Inc. (the “Corporation”), a corporation organized and existing under and by virtue of the General Corporation

Law of the State of Delaware (“DGCL”), DOES HEREBY CERTIFY:

FIRST:

On June 28, 2026, the Board of Directors of the Corporation duly approved resolutions designating as “Series C Non-Voting Convertible

Preferred Stock” (the “Series C Preferred”) an aggregate of 454,295 of the shares of preferred stock that the

Company is authorized to issue pursuant to its Third Amended and Restated Certificate of Incorporation, as amended (as amended the “Certificate

of Incorporation”), all as set forth in the Certificate of Designation of Preferences, Rights and Limitations of Series C Non-Voting

Convertible Preferred Stock of Ensysce Biosciences, Inc. filed with the Secretary of State of the State of Delaware on August 5, 2026

with a Certificate of Correction filed on August 6, 2026 (the “Series C Certificate of Designation”).

SECOND:

Pursuant to Sections 151, 228 and 242 of the DGCL, the Certificate of Incorporation and the Series C Certificate of Designation, on September

17, 2026, the Board of Directors of the Corporation adopted and approved the following resolution and on September 23, 2026, holders

of a majority of the outstanding shares of the Series C Preferred consented to such resolution, with the effect of amending the Certificate

of Designation as follows:

RESOLVED,

that the Series C Certificate of Designation is amended by (a) deleting Section 6.5.3 in its entirety and replacing it with “[Reserved]”

and (b) deleting references to Section 6.5.3 in Sections 6.2, 6.5.4 and Section 8.

*****

IN

WITNESS WHEREOF, Ensysce Biosciences, Inc. has caused this Certificate of Amendment to Certificate of Designation of Preferences,

Rights and Limitations of Series C Preferred Stock to be duly executed by the undersigned duly authorized officer as of this 24th

day of September, 2026.

ENSYSCE

BIOSCIENCES, INC.

By:

/s/

Dr. Lynn Kirkpatrick

Lynn

Kirkpatrick

Chief

Executive Officer

[Signature

Page to Certificate of Amendment to Certificate of Designation]

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Entity Tax Identification Number

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Entity Address, Address Line One

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