Knight Therapeutics Reports Second Quarter 2026 Results
Increased 2026 guidance and expect revenues of $540 million to $560 million
Achieved six month record-high revenues of $293 million and Adjusted EBITDA 1 of $52 million
MONTREAL, Aug. 06, 2026 (GLOBE NEWSWIRE) -- Knight Therapeutics Inc. (TSX: GUD) (“Knight” or “the Company”), a pan-American (ex-US) pharmaceutical company, today reported financial results for its second quarter ended June 30, 2026. All currency amounts are in thousands except for share and per share amounts. All currencies are Canadian unless otherwise specified.
Q2-26 Highlights
Financial Results - IFRS
Financial Results - Non-IFRS
Corporate developments
Products
Subsequent to quarter-end
“I am pleased to announce that we have delivered strong revenue growth and cash flow from operations. For the quarter ended June 30, 2026, revenues grew by 34% to $144 million and adjusted EBITDA 1 by 58% to over $24 million. This strong performance is the result of our commercial execution driving the growth of our promoted portfolio which increased by over $21 million or 30% in the second quarter, coming from our seventeen launches over the last two and a half years including four launches in the second quarter. I am also excited to announce that we are raising our financial outlook for fiscal 2026 and expect to deliver revenues between $540 million to $560 million. The momentum of our promoted products, the strength of our diversified portfolio and healthy cash flows from operations, position us well to continue executing on our mission of acquiring, in-licensing, developing and commercializing pharmaceutical products in Latin America and Canada.” said Samira Sakhia, President and Chief Executive Officer of Knight Therapeutics Inc.
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1 Adjusted Revenues, revenues on a constant currency basis, Adjusted Gross Margin, Adjusted EBITDA and Adjusted EBITDA per share are Non-IFRS measures and do not have any standardized meaning under IFRS. As a result, the information presented may not be comparable to similar measures presented by other companies. Refer to Section 7 - Financial Results under Non-IFRS measures for additional details.
2 Refers to the impact of hyperinflation due to the application of IAS 29 in Argentina. Refer to section - Hyperinflation for additional details.
Revenues: For the quarter ended June 30, 2026, revenues increased by $36,854 or 34% compared to the same period in prior year. On a constant currency 1 basis, the increase in revenues was $25,538 or 22%, driven by the following:
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1 Revenues on a constant currency basis is a Non-IFRS measure and does not have any standardized meaning under IFRS. As a result, the information presented may not be comparable to similar measures presented by other companies. Refer to section - Financial Results under Non-IFRS measures for additional details.
Gross margin: For the quarter ended June 30, 2026, gross margin was $69,615 or 48%, compared to $44,831 or 42% in Q2-25. Excluding the Gross Margin Hyperinflation Impact 1, the Adjusted Gross Margin 1 was $70,471 in Q2-26, an increase of $21,040 compared to Q2-25, due to the growth of revenues. The Adjusted Gross Margin 1 as a % of Adjusted Revenues 1, was 49% in Q2-26 compared to 46% in Q2-25. The increase was driven by the higher contribution of the Canadian business in Q2-26 compared to Q2-25.
Selling and marketing (“S&M”) expenses: For the quarter ended June 30, 2026, S&M expenses increased by $6,180 or 39% and by $4,690 or 27% on a constant currency 1 basis. The increase was mainly driven by an expansion in our sales and commercial structure to support the larger Canadian portfolio, the recent launches of Jornay PM ®, Xcopri ®, Myfembree ® and Orgovyx ®, as well as the launches of Minjuvi ® and Tavalisse ® in Mexico. In addition to structure, the increase also included our promotion and marketing expenses for Orgovyx ®, Myfembree ®, Xcopri ® and Envarsus ®PA, as well as for the recently launched brands including Jornay PM ® in Canada, Minjuvi ® in Mexico and Argentina, Pemazyre ® in Mexico, Brazil and Argentina, Tavalisse ® in Mexico and pre-launch activities including Tavalisse ® in Brazil.
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1 Adjusted Revenues, Adjusted Gross Margin, revenues and financial results on a constant currency basis, are Non-IFRS measures and do not have any standardized meaning under IFRS. As a result, the information presented may not be comparable to similar measures presented by other companies. Refer to section - Financial Results under Non-IFRS measures for additional details.
2 Refers to the impact of hyperinflation due to the application of IAS 29 in Argentina. Refer to section - Hyperinflation for additional details.
General and administrative (“G&A”) expenses: For the quarter ended June 30, 2026, G&A expenses decreased by $1,033 or 7% and by $1,689 or 10% on a constant currency 1 basis. The decrease was mainly driven by the acquisition and transaction costs of $3,430 related to the Paladin Transaction incurred in Q2-25, partly offset by an increase in our structure following the addition of the Paladin and Sumitomo portfolios, as well as higher spending on professional and consulting fees.
Research and development (“R&D”) expenses: For the quarter ended June 30, 2026, R&D expenses increased by $4,280 or 68% and by $3,748 or 55% on a constant currency 1 basis. The increase was mainly due to the expansion of our scientific affairs structure including field‑based medical personnel related to the larger Canadian portfolio. In addition to structure, the increase included incremental medical, regulatory, and pharmacovigilance spend on the Paladin and Sumitomo portfolios, as well as development, regulatory, pre‑launch, and launch expenses on our pipeline and new launches, including Gemtesa ®, Jornay PM ®, Crexont ®, Niktimvo ® and Tavalisse ®.
Net Loss
For the quarter ended June 30, 2026, the net loss was $3,361 compared to $12,622 for the same period in prior year. The variance was mainly driven by the above-mentioned items, as well as changes in amortization of intangible assets, net loss on financial assets measured at fair value through profit or loss, foreign exchange loss, gain on hyperinflation, interest expense, and income tax expense.
1 A positive variance represents a positive impact to net assets and a negative variance represents a negative impact to net assets.
2 Percentage change is presented in absolute values.
Cash, cash equivalents and marketable securities: As at June 30, 2026, cash, cash equivalents and marketable securities were $109,600, an increase of $14,317 or 15%, compared to December 31, 2025. The increase was mainly driven by operating cash inflows of $70,217, and proceeds of $17,000 for the return of the Canadian commercial rights for certain non-core products. These increases were partly offset by principal repayments of bank loans of $48,565, the repurchase of common shares under the NCIB of $9,275, holdback payment of $8,442 related to the Paladin acquisition, investment in intangible assets of $5,132, and the acquisition of a manufacturing facility in Argentina of $2,950.
Trade and other receivables: As at June 30, 2026, trade and other receivables were $183,146, an increase of $4,548 or 3%, compared to December 31, 2025, mainly due to the receivable of $4,500 related to the return of the Canadian commercial rights of six non-core products. The amount was collected in July 2026.
Inventories: As at June 30, 2026, inventories were $144,572, an increase of $8,706 or 6%, compared to December 31, 2025, primarily due to the timing of purchases and foreign exchange revaluation, partly offset by sales during the period.
Financial assets: As at June 30, 2026, financial assets were $81,395, a decrease of $17,035 or 17%, compared to December 31, 2025. This was driven by a $9,661 reduction in fund investments, mainly due to a decrease in fair value of $9,352 and a $7,374 reduction in equity investments, primarily reflecting the revaluation of our publicly traded equity investments and the disposal of certain equities, including Crescita.
Intangible assets: As at June 30, 2026, intangible assets were $344,861, a decrease of $34,649 or 9%, compared to December 31, 2025, primarily due to the derecognition of intangible assets in connection with the return of the Canadian commercial rights of six non-core products, as well as amortization, partly offset by foreign exchange revaluation.
Accounts payable and accrued liabilities: As at June 30, 2026, accounts payable and accrued liabilities were $141,653, an increase of $15,898 or 13%, compared to December 31, 2025, mainly driven by the timing of purchases of inventory.
Bank Loans: As at June 30, 2026, bank loans were $23,133, a decrease of $44,762 or 66%, compared to December 31, 2025, mainly due to the repayment of $40,000 on the revolving credit facility.
Corporate Updates
Revolving Credit Facility
In June 2025, the Company withdrew $60,000 from the revolving credit facility to fund a portion of the Paladin Transaction. Knight repaid the full amount within twelve months of the withdrawal, funded entirely by cash flow generated from operations. Repayments were made as follows: (1) $20,000 in December 2025, (2) $10,000 in February 2026, (3) $10,000 in April 2026, and (4) $20,000 in June 2026.
Q2-26 Product Updates
Tavalisse ® (fostamatinib disodium hexahydrate)
Knight obtained the regulatory approval of Tavalisse ® in Brazil and expects to launch in the second half of 2026. Knight also launched Tavalisse ® in Mexico during the quarter for the treatment of adult patients with chronic immune thrombocytopenia who have had an insufficient response to a previous treatment.
Molapib ® (olaparib)
Molapib ® obtained regulatory approval and launched in Argentina. Molapib ® is a PARP inhibitor indicated for the treatment for certain types of advanced cancers in adult patients, including ovarian, breast, pancreatic and prostate cancers, under specific biomarker-defined conditions and treatment settings.
Pemazyre ® (pemigatinib)
Knight launched Pemazyre ® in Argentina, as monotherapy, for the treatment of adults with locally advanced or metastatic cholangiocarcinoma with a FGFR2 fusion or rearrangement which has progressed following at least one prior line of systemic therapy.
Akynzeo ® (netupitant/palonosetron/fosnetupitant/palonosetron)
Knight launched Akynzeo ® in Paraguay in combination with dexamethasone, for the prevention of acute and delayed nausea and vomiting associated with moderately to highly emetogenic chemotherapy.
Qelbree ® (viloxazine)
Knight withdrew the Health Canada New Drug Submission for Qelbree ® due to certain manufacturing changes by our partner. Knight expects to resubmit Qelbree ® for approval at a later date. The submission is expected to include both the data required for the manufacturing changes as well as the additional information previously requested by Health Canada in the Notice of Non-Compliance issued in Q4-25.
Impavido ® (miltefosine)
Knight entered into a supply and distribution agreement with Eton Pharmaceuticals, Inc. for the U.S. commercialization rights to Impavido ® (miltefosine). Eton will assume exclusive U.S. commercialization rights of Impavido ® effective September 26, 2026. Impavido ® is an orphan drug and the first and only FDA-approved oral therapy for the treatment of visceral, cutaneous, and mucosal leishmaniasis due to specific Leishmania species in adults and adolescents 12 years of age and older weighing greater than or equal to 30 kg.
Lenvima ® (lenvatinib)
Colombia’s Ministry of Health published the list of medicines subject to the direct price control regime and added lenvatinib to the list. The inclusion of lenvatinib is effective August 19, 2026, and will result in a decrease in the selling price of lenvatinib. In addition, INVIMA approved a generic version of lenvatinib 10 mg. The Company expects these developments to negatively impact sales and the adjusted EBITDA of Lenvima ® in Colombia.
Crexont ® (carbidopa and levodopa)
On August 5, 2026, Knight received a Notice of Non-Compliance from Health Canada for its New Drug Submission for Crexont ®, for the treatment of Parkinson’s disease. Knight will work with its partner to prepare a response to Health Canada.
Financial Outlook 1
For the fiscal 2026, Knight has increased its financial guidance on revenues and now expects to generate between $540 million to $560 million in revenues, up from $510 million to $525 million. The adjusted EBITDA 2 is expected to be at least 15% of revenues. The increase in our revenue outlook is driven primarily by the stronger performance of our promoted products across multiple countries as well as select LATAM currencies performing better against the Canadian dollar than previously anticipated. The guidance is based on a number of assumptions, including but not limited to the following:
Should any of the assumptions differ, the financial outlook and the actual results may vary materially. Refer to the risks and assumptions referred to in the Forward-Looking Statements section of this news release for further details.
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1 This forward looking information is based on assumptions specific to the nature of the Company’s activities with regard to annual revenue growth considering industry information, expected market share, pricing assumptions, actions of competitors, sales erosion rates after the end of patent or other intellectual property rights protection, the timing of the entry of generic competition, the expected results of tenders, among other variables.
2 Adjusted EBITDA is a Non-IFRS measure and does not have any standardized meaning under IFRS. As a result, the information presented may not be comparable to similar measures presented by other companies. Refer to section - Financial Results under Non-IFRS measures for additional details.
Conference Call Notice
Knight will host a conference call and audio webcast to discuss its second quarter ended June 30, 2026, today at 8:30 am ET. Knight cordially invites all interested parties to participate in this call.
Date: Thursday, August 6, 2026
Time: 8:30 a.m. ET
Telephone: Toll Free: 1-888-699-1199 or International 1-416-945-7677
Webcast: www.knighttx.com or Webcast
This is a listen-only audio webcast. Media Player is required to listen to the broadcast.
Replay: An archived replay will be available for 30 days at www.knighttx.com
About Knight Therapeutics Inc.
Knight Therapeutics Inc., headquartered in Montreal, Canada, is a pharmaceutical company focused on acquiring, in-licensing and commercializing pharmaceutical products for Canada and Latin America. Knight's Latin American subsidiaries operate under United Medical, Biotoscana Farma and Laboratorio LKM. Knight Therapeutics Inc.'s shares trade on the TSX under the symbol GUD. For more information about Knight Therapeutics Inc., please visit the company's web site at www.knighttx.com or www.sedarplus.ca.
Forward-Looking Statement
This document contains forward-looking statements for Knight Therapeutics Inc. and its subsidiaries. These forward-looking statements, by their nature, necessarily involve risks and uncertainties that could cause actual results to differ materially from those contemplated by the forward-looking statements. Knight Therapeutics Inc. considers the assumptions on which these forward-looking statements are based to be reasonable at the time they were prepared but cautions the reader that these assumptions regarding future events, many of which are beyond the control of Knight Therapeutics Inc. and its subsidiaries, may ultimately prove to be incorrect. Factors and risks, which could cause actual results to differ materially from current expectations are discussed in Knight Therapeutics Inc.'s Annual Report and in Knight Therapeutics Inc.'s Annual Information Form for the year ended December 31, 2025 as filed on www.sedarplus.ca. Knight Therapeutics Inc. disclaims any intention or obligation to update or revise any forward-looking statements whether because of new information or future events, except as required by law.
CONTACT INFORMATION:
HYPERINFLATION
The Company applies IAS 29, Financial Reporting in Hyperinflation Economies, as the Company’s Argentine subsidiary uses the Argentine Peso as its functional currency. IAS 29 requires that the financial statements of an entity whose functional currency is that of a hyperinflationary economy be adjusted based on an appropriate general price index to reflect the effects of inflation. After applying for the effects of hyperinflation, the statement of income (loss) is converted using the closing foreign exchange rate of the month.
Revenues and operating expenses in the local currency, i.e. ARS, are restated from the month of the sales or the month in which the expense was incurred to the end of the reporting period using the inflation index during that period. The restatement calculation is performed on a year to date basis based on IAS 29 ("Inflation Adjusted Figures"). For the six-month period ended June 30, 2026 and 2025, the Company applied the following inflation index for the restatement of each respective month.
Under IAS 29, the translation from the local currency, to the reporting currency is performed on the Inflation Adjusted Figures using the end of period rate at the reporting date. The Inflation Adjusted Figures were converted to CAD using the following quarter-end closing rates for each of the respective periods.
1 Appreciation (depreciation) of ARS vs CAD during each period, calculated as follows: (End of period rate - Beginning of period rate) / Beginning of period rate.
Accordingly, the application of hyperinflation accounting under IAS 29 resulted in higher reported revenues and operating expenses, in CAD, for the Company's Argentine subsidiary in both Q2-26 and YTD-26 compared with the corresponding prior-year periods ("Hyperinflation Impact"). Under hyperinflation accounting, cost of goods sold denominated in ARS is restated using the inflation index from the inventory purchase or production date to the end of the reporting period and translated into CAD using the applicable quarter-end closing rates. In Q2-26 and YTD-26, the cumulative inflation adjustment applied to inventory sold was lower than in the corresponding prior-year periods, resulting in lower cost of goods sold reported under IAS 29 in CAD and, consequently, a higher gross margin.
FINANCIAL RESULTS UNDER NON-IFRS MEASURES
[In thousands of Canadian dollars]
The Company discloses Non-IFRS measures and ratios that do not have standardized meanings prescribed by IFRS. The Company believes that shareholders, investment analysts and other readers find such measures helpful in understanding the Company’s financial performance. Non-IFRS financial measures and Adjusted EBITDA per share ratio do not have any standardized meaning prescribed by IFRS and may not have been calculated in the same way as similarly named financial measures presented by other companies. The Company uses the following Non-IFRS measures.
[i] Financial results excluding the impacts of hyperinflation under IAS 29
The Company applies IAS 29, Financial Reporting in Hyperinflation Economies, as the Company's Argentine subsidiary uses the Argentine Peso as their functional currency. IAS 29 requires that the financial statements of an entity whose functional currency is the currency of a hyperinflationary economy be adjusted based on an appropriate general price index to express the effects of inflation.
Financial results under IFRS are adjusted to remove the impact of hyperinflation under IAS 29. The impact of hyperinflation under IAS 29 is calculated by applying an appropriate general price index to express the effects of inflation. After applying the effects of translation, the statement of income is converted using the closing foreign exchange rate of the month.
The Company believes that financial results excluding the impact of hyperinflation under IAS 29 represents a useful measure to investors as they allow results to be viewed without those impacts, thereby facilitating the comparison of results period over period. The presentation of financial results excluding the impact of hyperinflation under IAS 29 is considered to be a Non-IFRS measure and does not have any standardized meaning under IFRS. As a result, the information presented may not be comparable to similar measures presented by other companies.
The following tables are reconciliations of financial results under IFRS to financial results excluding the impact of hyperinflation under IAS 29.
Select financial results excluding the impact of hyperinflation under IAS 29 1
Adjusted Revenues 1 by Product Portfolio
Adjusted Revenues 1 by Therapeutic Area
[ii] Financial results at constant currency
Financial results at constant currency are obtained by translating the prior period revenues and financial results from the functional currencies to CAD using the conversion rates in effect during the current period. Furthermore, with respect to Argentina, the Company excludes the impact of hyperinflation and translates the revenues and results at the average exchange rate in effect for each of the periods.
The Company believes that financial results at constant currency represents a useful measure to investors because it eliminates the effect that foreign currency exchange rate fluctuations may have on period-to-period comparability given the volatility in foreign currency exchange markets and therefore, provides greater transparency to the underlying performance of our consolidated financial results. The presentation of revenues and financial results under constant currency is considered to be a Non-IFRS measure and does not have any standardized meaning under IFRS. As a result, the information presented may not be comparable to similar measures presented by other companies.
The following tables are reconciliations of financial results under IFRS to financial results and financial results at constant currency.
Adjusted Revenues at Constant Currency 1 by Product Portfolio
Adjusted Revenues at Constant Currency 1 by Therapeutic Area
[iii] Adjusted Gross Margin
Adjusted Gross Margin is defined as revenues less cost of goods sold, adjusted for the impact of IAS 29. The Company believes that Adjusted Gross Margin represents a useful measure to investors to assess Gross Margin without the impact of hyperinflation under IAS 29, thereby facilitating the comparison period over period. The presentation of Adjusted Gross Margin is considered to be a Non-IFRS measure and does not have any standardized meaning under IFRS. As a result, the information presented may not be comparable to similar measures presented by other companies.
[iv] EBITDA
EBITDA is defined as operating income or loss adjusted to exclude amortization and impairment of non-current assets, depreciation, but to include costs related to leases.
The Company believes that EBITDA represents a useful measure to investors to assess profitability and measure the Company's ability to generate liquidity through operating activities. The presentation of EBITDA is considered to be a Non-IFRS measure and does not have any standardized meaning under IFRS. As a result, the information presented may not be comparable to similar measures presented by other companies.
[v] Adjusted EBITDA
Adjusted EBITDA is defined as EBITDA adjusted for the impact of IAS 29 (accounting under hyperinflation), acquisition and transaction costs and non-recurring expenses. The Company believes that Adjusted EBITDA represents a useful measure to investors to assess profitability and measure the Company's ability to generate liquidity through operating activities. The presentation of adjusted EBITDA is considered to be a Non-IFRS measure and does not have any standardized meaning under IFRS. As a result, the information presented may not be comparable to similar measures presented by other companies.
The following table is a reconciliation of operating income (loss) to EBITDA and adjusted EBITDA:
For the quarter ended June 30, 2026, adjusted EBITDA increased by $9,062 or 58%. The increase was mainly driven by higher Adjusted Gross Margin 1, partly offset by higher operating expenses. Refer to Section 3 - Results of Operations of the MD&A for further details.
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1 Adjusted Gross Margin is a Non-IFRS measures and do not have any standardized meaning under IFRS. As a result, the information presented may not be comparable to similar measures presented by other companies.
Explanation of adjustments from EBITDA to Adjusted EBITDA
[vi] Adjusted EBITDA per share
Adjusted EBITDA per share is defined as Adjusted EBITDA divided by the number of common shares outstanding at the end of the respective period. The Company believes that Adjusted EBITDA per share represents a useful measure to investors to assess profitability and measure the Company's ability to generate liquidity through operating activities on a per common share basis, without the impact of hyperinflation under IAS 29, acquisition and transaction costs and non-recurring expenses, thereby facilitating the comparison period over period. The presentation of adjusted EBITDA per share is considered to be a Non-IFRS ratio and does not have any standardized meaning under IFRS. As a result, the information presented may not be comparable to similar measures presented by other companies.
The Company calculated Adjusted EBITDA per share as follows: