Form 8-K

8-K — Editas Medicine, Inc.

Accession: 0001650664-26-000082

Filed: 2026-08-05

Period: 2026-08-03

CIK: 0001650664

SIC: 2836 (BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES))

Item: Results of Operations and Financial Condition

Item: Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers

Item: Financial Statements and Exhibits

Documents

8-K — edit-20260803.htm (Primary)

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UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, D.C. 20549

_________________________________________________________________________________________

FORM 8-K

_________________________________________________________________________________________

CURRENT REPORT

Pursuant to Section 13 or 15(d)

of The Securities Exchange Act of 1934

Date of Report (Date of earliest event reported): August 3, 2026

_________________________________________________________________________________________

Editas Medicine, Inc.

(Exact Name of Registrant as Specified in its Charter)

_________________________________________________________________________________________

Delaware 001-37687 46-4097528

(State or Other Jurisdiction of Incorporation) (Commission File Number) (IRS Employer Identification No.)

11 Hurley Street

Cambridge, Massachusetts 02141

(Address of Principal Executive Offices) (Zip Code)

Registrant’s telephone number, including area code: (617) 401-9000

(Former Name or Former Address, if Changed Since Last Report)

__________________________________________________________________________________________________

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (see General Instruction A.2. below):

o Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

o Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

o Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

o Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to Section 12(b) of the Act:

Title of each class Trading Symbol(s) Name of each exchange on which registered

Common Stock, $0.0001 par value per share EDIT The Nasdaq Stock Market LLC

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).

Emerging growth company o

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. o

Item 2.02 Results of Operations and Financial Condition.

On August 5, 2026, Editas Medicine, Inc. (the “Company”) issued a press release announcing financial results for the fiscal quarter ended June 30, 2026 and other business highlights. A copy of the press release is being furnished as Exhibit 99.1 to this Current Report on Form 8-K.

The information contained in Item 2.02 in this Current Report on Form 8-K (including Exhibit 99.1) shall not be deemed “Filed” for purposes of Section 18 of the Securities Exchange Act of 1934 (the “Exchange Act”) or otherwise subject to the liabilities of that section, nor shall it be deemed incorporated by reference in any filing under the Securities Act of 1933 or the Exchange Act, except as expressly set forth by specific reference in such a filing.

Item 5.02 Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.

On August 3, 2026, Elliott Levy, M.D., a member of the Board of Directors (the “Board”) of the Company who was serving as a class I director, resigned from the Board, effective August 4, 2026. The resignation was not the result of any disagreement with the Company on any matter relating to the Company’s operations, policies or practices.

On August 4, 2026, the Board, upon recommendation of the Board’s Nominating and Corporate Governance Committee, appointed Patrick Ellinor, M.D., Ph.D. as an independent director, effective August 6, 2026. Dr. Ellinor has been designated as a class I director to serve in accordance with the Company’s By-Laws.

Dr. Ellinor currently serves as Executive Director of the Heart and Vascular Institute at Mass General Brigham, a role he has held since December 2024. He has also served as an Institute Member and Director of the Cardiovascular Disease Initiative of the Broad Institute of Harvard and MIT since October 2014, as a Professor of Medicine at Harvard Medical School since July 2003, and as the Telemachus and Irene Demoulas Family Foundation Endowed Chair in Cardiology at Massachusetts General Hospital since June 1998. Dr. Ellinor received a B.S. in Biology from the University of Cincinnati and both a Ph.D. in Physiology and an M.D. from Stanford University. He did his medical internship and residency at Brigham and Women’s Hospital in Boston and completed fellowship training in cardiology and cardiac electrophysiology at Massachusetts General Hospital.

In accordance with the Company’s director compensation policy, Dr. Ellinor will receive (i) annual cash compensation of $40,000 as a member of the Board and reimbursement for reasonable travel and other expenses incurred in connection with attending meetings of the Board and committees thereof and (ii) an option to purchase 103,400 shares of the Company’s common stock, with an exercise price equal to the closing price of the Company’s common stock on the Nasdaq Global Select Market on the date of appointment, which option will vest as to one-third of the shares of common stock underlying the option in three equal installments on each anniversary of the date of grant. Dr. Ellinor has entered into a standard form of indemnification agreement with the Company, in the form that is filed as Exhibit 10.28 to the Company’s Registration Statement on Form S-1 (File No. 333-208856), filed with the Securities and Exchange Commission on January 4, 2016.

There is no arrangement or understanding between Dr. Ellinor and any other person pursuant to which Dr. Ellinor was selected as a director. In addition, Dr. Ellinor is not a party to any transaction, or series of transactions, required to be disclosed pursuant to Item 404(a) of Regulation S-K.

Item 9.01 Financial Statements and Exhibits.

(d)Exhibits

Exhibit

No. Description

99.1

Press release issued by the Company on August 5, 2026*

104 Cover Page Interactive Data File (embedded within the Inline XBRL document)

*This exhibit shall be deemed to be furnished and not filed.

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, as amended, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

EDITAS MEDICINE, INC.

Date: August 5, 2026 By: /s/ Amy Parison

Amy Parison

Chief Financial Officer

EX-99

Filename: editasmedicinepressrelease.htm · Sequence: 2

Document

Exhibit 99.1

Editas Medicine Announces Second Quarter 2026 Results and Business Updates

EDIT-401 on track for CTN submission this month with data update in Q1 2027

Recently presented pre-clinical data demonstrating ~90% or greater mean reduction in multiple atherogenic lipoproteins, including LDL-C, Lp(a) and ApoB with EDIT-401 in non-human primates

Recent financing strengthens Company’s capital position, supporting continued advancement of EDIT-401 program, with cash runway into the second half of 2028

CAMBRIDGE, Mass., August 5, 2026 – Editas Medicine, Inc. (Nasdaq: EDIT), a pioneering gene editing company focused on developing transformative medicines for serious diseases, today reported financial results for the second quarter 2026 and provided business updates.

“During the second quarter, we continued preclinical work to support advancing EDIT-401 into a single ascending dose, open-label Phase 1/2 study,” said Gilmore O’Neill, M.B., M.M.Sc., President and Chief Executive Officer of Editas Medicine. “We also presented new preclinical data demonstrating the ability of a single dose of EDIT-401 to achieve rapid and significant reductions in multiple atherogenic lipoproteins in non-human primates along with a promising preclinical safety profile, reinforcing EDIT-401’s potential as a best-in-class, one-time treatment for hyperlipidemia. In addition, with our recent equity financing, we are well capitalized to drive the clinical development of EDIT-401 through key value-creating milestones. We look forward to our continued progress and expect to provide a data update in the first quarter of 2027.”

EDIT-401

•Editas presented new EDIT-401 preclinical data at the 94th European Atherosclerosis Society (EAS) Congress, the 2026 Annual Meeting of the American Society of Gene and Cell Therapy (ASGCT), and TIDES USA 2026: Oligonucleotide and Peptide Therapeutics Conference, including:

◦A single dose of EDIT-401 achieved ~90 percent or greater mean reductions in LDL cholesterol (LDL-C), lipoprotein(a) (Lp(a)), and apolipoprotein B (ApoB), with rapid and dose-dependent effect, in non-human primates (NHPs).

◦LDL-C mean reduction of ≥90% with a single dose of EDIT-401 in NHPs was durable through ~6 months.

◦No adverse clinical observations were observed in NHPs at a single dose of 1.5mg/kg.

•Editas is on track to submit a Clinical Trial Notification (CTN) in Australia this month and continues to progress towards initiating a Phase 1/2 clinical trial of EDIT-401 in patients with Heterozygous Familial Hypercholesterolemia (HeFH).

◦The Phase 1/2 study will evaluate the safety, tolerability, and efficacy of a single dose of EDIT-401. The trial is designed in two parts. Part 1 of the study is a single ascending dose, open-label trial design. Editas has selected four clinical trial sites across Australia and New Zealand.

◦The Company expects to report a data update in the first quarter of 2027.

◦Editas plans to complete enrollment in Part 1, the dose-finding portion of the Phase 1/2 trial of EDIT-401, with topline data results available in 2027.

Corporate & Business Development Updates

•In May, Editas completed a public offering of common stock and accompanying common stock warrants. The aggregate gross proceeds from the offering were $125.0 million, before deducting underwriting discounts and commissions and offering expenses. In addition, if all common stock warrants are exercised at their exercise price, the Company would receive additional gross proceeds from the offering of approximately $194.4 million before deducting underwriting discounts and commissions and offering expenses.

•Editas announced the appointment of Patrick T. Ellinor, M.D., Ph.D. to its Board of Directors. Dr. Ellinor is a recognized leader in cardiovascular medicine and human genetics and brings extensive experience spanning scientific innovation, therapeutic discovery, and clinical leadership to Editas.

Second Quarter 2026 Financial Results

Cash and cash equivalents as of June 30, 2026, were $211.6 million compared to $146.6 million as of December 31, 2025. The Company expects that the existing cash and cash equivalents will enable the Company to fund its operating expenses and capital expenditure requirements into the second half of 2028.

Second Quarter 2026

•For the three months ended June 30, 2026, net loss attributable to common stockholders was $18.2 million, or $0.15 per share, compared to net loss of $53.2 million, or $0.63 per share, for the same period in 2025.

•Collaboration and other research and development revenues increased to $11.9 million for the three months ended June 30, 2026, compared to $3.6 million for the same period in 2025. The increase was primarily attributable to the recognition of deferred revenue related to the expiration certain rights to opt-in to additional research programs under its collaboration with BMS.

•Research and development expenses increased by $4.0 million to $20.2 million for the three months ended June 30, 2026, compared to $16.2 million for the same period in 2025. The decrease is primarily related to increased external expenses for ongoing research and preclinical efforts for EDIT-401.

•General and administrative expenses decreased by $1.3 million to $11.6 million for the three months ended June 30, 2026 compared to $12.9 million for the same period in 2025. The decrease is primarily attributable to a reduction in employee-related expenses, as well as reduced professional services, in connection with the reduction in headcount (the “Reduction”) and discontinuation of the clinical development of the Company’s reni-cel program (the “Discontinuation”) initiated in December 2024 and ongoing throughout 2025.

•Restructuring and impairment charges decreased by $27.4 million to a $1.3 million benefit for the three months ended June 30, 2026 compared to $26.1 million for the same period in 2025. The decrease is primarily attributable to favorable adjustments to prior estimated costs for contracts associated with the Discontinuation upon finalization of contract costs.

About Heterozygous Familial Hypercholesterolemia (HeFH)

Heterozygous Familial Hypercholesterolemia (HeFH) is an inherited genetic disorder that leads to significantly elevated LDL‑cholesterol levels from an early age. Individuals with HeFH are at high risk of heart disease, heart attack, or stroke if the condition is not identified and treated early. An estimated 1.2 million people in the United States are living with HeFH, though many remain undiagnosed. Elevated LDL-C, also known as hyperlipidemia, is a highly prevalent disease affecting over 70 million patients in the United States alone. Substantial unmet need exists across multiple at-risk segments of patients with hyperlipidemia, including the HeFH population.

About Editas Medicine

As a pioneering gene editing company, Editas Medicine is focused on translating the power and potential of the CRISPR genome editing systems into a robust pipeline of transformative in vivo medicines for people living with serious diseases around the world. Editas Medicine aims to discover, develop, manufacture, and commercialize durable, precision in vivo gene editing medicines for a broad class of diseases. Editas Medicine is the exclusive licensee of Broad Institute’s Cas12a patent estate and Broad Institute and Harvard University’s Cas9 patent estates for human medicines. For the latest information and scientific presentations, please visit www.editasmedicine.com.

Forward-Looking Statements

This press release contains forward-looking statements and information within the meaning of The Private Securities Litigation Reform Act of 1995. The words ‘‘anticipate,’’ ‘‘believe,’’ ‘‘continue,’’ ‘‘could,’’ ‘‘estimate,’’ ‘‘expect,’’ ‘‘intend,’’ ‘‘may,’’ ‘‘plan,’’ ‘‘potential,’’ ‘‘predict,’’ ‘‘project,’’ ‘‘target,’’ ‘‘should,’’ ‘‘would,’’ and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. Forward-looking statements in this press release include statements regarding the initiation, timing, progress and results of the Company’s preclinical studies and planned clinical trials, including the Company’s expectation to complete enrolling the dose-finding portion of the planned Phase 1/2 clinical trial of EDIT-401 with topline data results available in 2027; the timing for the Company’s receipt and presentation of data from its preclinical and planned clinical studies, including providing a data update on EDIT-401 in the first quarter of 2027; the potential of, and expectations for, EDIT-401; the timing or likelihood of regulatory submissions and approvals, including submission of a CTN in Australia this month; and the Company’s expectations regarding its cash runway. The Company may not actually achieve the plans, intentions, or expectations disclosed in these forward-looking statements, and you should not place undue reliance on these forward-looking statements. Actual results or events could differ materially from the plans, intentions and expectations disclosed in these forward-looking statements as a result of various important factors, including: uncertainties inherent in the initiation, timing, progress, and results of preclinical studies and clinical trials; uncertainty regarding availability and timing of results from preclinical studies and clinical trials; uncertainties relating to planned regulatory submissions to initiate clinical trials, including that results of preclinical studies will warrant such submissions or that regulatory agencies may require additional preclinical studies, that regulatory submissions shall occur on the expected timelines and that regulatory authorities will provide clearance for trials to be initiated on the expected timelines or at all; and uncertainties as to whether the Company’s cash resources are sufficient to fund its foreseeable and unforeseeable operating expenses and capital expenditure requirements for the period anticipated. These and other risks are described in greater detail under the caption “Risk Factors” included in the Company’s most recent Annual Report on Form 10-K, which is on file with the Securities and Exchange Commission, as updated by the Company’s subsequent filings with the Securities and Exchange Commission, and in other filings that the Company may make with the Securities and Exchange Commission in the future. Any forward-looking statements contained in this press release represent the Company’s views only as of the date hereof and should not be relied upon as representing its views as of any subsequent date. Except as required by law, the Company explicitly disclaims any obligation to update any forward-looking statements.

This press release contains hyperlinks to information that is not deemed to be incorporated by reference in this press release.

EDITAS MEDICINE, INC.

Consolidated Statement of Operations

(amounts in thousands, except share and per share data)

(Unaudited)

Three Months Ended

June 30, Six Months Ended

June 30,

2026 2025 2026 2025

Collaboration and other research and development revenues $ 11,890 $ 3,578 $ 14,721 $ 8,236

Operating expenses:

Research and development 20,180 16,181 37,780 42,774

General and administrative 11,603 12,859 21,837 26,234

Restructuring and impairment charges (1,339) 26,082 (1,339) 66,935

Total operating expenses 30,444 55,122 58,278 135,943

Operating loss (18,554) (51,544) (43,557) (127,707)

Other income (expense), net:

Interest expense related to sale of future revenues (1,061) (2,020) (2,133) (4,236)

Interest income, net 1,368 2,087 2,574 4,803

Other income (expense), net 17 (1,758) (96) (2,183)

Total other income (expense), net 324 (1,691) 345 (1,616)

Net loss $ (18,230) $ (53,235) $ (43,212) $ (129,323)

Net loss per share, basic and diluted $ (0.15) $ (0.63) $ (0.40) $ (1.54)

Weighted-average common shares outstanding, basic and diluted 119,294,615 84,412,200 108,646,137 83,737,382

EDITAS MEDICINE, INC.

Selected Consolidated Balance Sheet Items

(amounts in thousands)

(Unaudited)

June 30, December 31,

2026 2025

Cash and cash equivalents $ 211,645 $ 146,645

Working capital 149,633 117,649

Total assets 237,364 186,534

Deferred revenue, net of current portion 4,000 44,509

Total stockholders' equity 105,281 27,288

###

Investor and Media Contacts:

ir@editasmed.com

media@editasmed.com

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