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Form 8-K

sec.gov

8-K — Barinthus Biotherapeutics plc.

Accession: 0001104659-26-037698

Filed: 2026-03-31

Period: 2026-03-27

CIK: 0001828185

SIC: 2834 (PHARMACEUTICAL PREPARATIONS)

Item: Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers

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UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 8-K

CURRENT REPORT

Pursuant to Section 13 or 15(d)

of the Securities Exchange Act of 1934

Date

of Report (Date of earliest event reported): March 27, 2026

BARINTHUS BIOTHERAPEUTICS PLC

(Exact name of registrant as specified in its

charter)

England and Wales

001-40367

Not Applicable

(State or other jurisdiction

of incorporation)

(Commission

File Number)

(I.R.S. Employer

Identification No.)

Barinthus Biotherapeutics plc

20400 Century Blvd, Suite 210

Germantown,

MD 20874

(Address of principal executive offices, including

zip code)

443 917-0966

(Registrant’s telephone number, including

area code)

Not Applicable

(Former name or former address, if changed since

last report)

Check the appropriate box below if the Form 8-K filing is intended

to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

¨

Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

¨

Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

¨

Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

¨

Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to Section 12(b) of the Act:

Title of each class

Trade Symbol(s)

Name of each exchange on which

registered

American Depositary Shares

BRNS

The Nasdaq Global Market

Ordinary shares, nominal value £0.000025 per share*

Indicate by check mark whether the registrant is an emerging growth

company as defined in Rule 405 of the Securities Act of 1933 (§ 230.405 of this chapter) or Rule 12b-2 of the Securities Exchange

Act of 1934 (§ 240.12b-2 of this chapter).

Emerging growth company  x

If an emerging growth company, indicate by check mark if the registrant

has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant

to Section 13(a) of the Exchange Act.  ¨

*

American Depositary Shares may be evidenced by American Depositary Receipts. Each American Depositary Share represents one (1) ordinary

share. Not for trading, but only in connection with the listing of the American Depositary Shares on The Nasdaq Global Market. The American

Depositary Shares represent the right to receive ordinary shares and are being registered under the Securities Act of 1933, as amended,

pursuant to a separate Registration Statement on Form F-6. Accordingly, the American Depositary Shares are exempt from the operation

of Section 12(a) of the Securities Exchange Act of 1934, as amended, pursuant to Rule 12a-8.

00-0000000

Item 5.02. Departure of Directors or Certain Officers; Election

of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.

As previously disclosed, Gemma Jones provides services to Barinthus

Biotherapeutics plc (the “Company”) as an employee of CFGI and serves as the Company’s principal accounting officer.

On March 27, 2026, Ms. Jones notified the Company that she will step down as the Company’s principal accounting officer,

effective as of April 30, 2026.

Forward Looking Statements

This Current Report on Form 8-K contains forward-looking statements,

within the meaning of the Private Securities Litigation Reform Act of 1995, as amended, which can generally be identified as such by use

of the words “expect,” “will,” and similar expressions, although not all forward-looking statements contain these

identifying words. These forward-looking statements include, without limitation, express or implied statements regarding the intended

departure of the Company’s principal accounting officer and the timing thereof. Any forward-looking statements in this Current Report

on Form 8-K are based on management’s current expectations and beliefs and are subject to numerous risks, uncertainties and

important factors that may cause actual events or results to differ materially from those expressed or implied by any forward-looking

statements contained in this Current Report on Form 8-K, including, without limitation, risks and uncertainties related to the success,

cost and timing of the Company’s pipeline development activities and planned and ongoing clinical trials, the Company’s ability

to execute on its strategy, regulatory developments, the risk that the Company may not achieve the anticipated benefits of its pipeline

prioritization and corporate restructuring, the Company’s ability to fund its operations and access capital, the Company’s

preliminary estimates of its cash and cash equivalents, including the risk that final financial results may differ materially from the

Company’s preliminary estimates, and other risks identified in the Company’s filings with the Securities and Exchange Commission

(the “SEC”), including its Annual Report on Form 10-K for the year ended December 31, 2025, its Quarterly Reports

on Form 10-Q and subsequent filings with the SEC. The Company cautions you not to place undue reliance on any forward-looking statements,

which speak only as of the date they are made. The Company expressly disclaims any obligation to publicly update or revise any such statements

to reflect any change in expectations or in events, conditions or circumstances on which any such statements may be based, or that may

affect the likelihood that actual results will differ from those set forth in the forward-looking statements.

SIGNATURE

Pursuant to the requirements of the Securities Exchange Act of 1934,

the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

Barinthus Biotherapeutics plc

Date: March 31, 2026

By:

/s/ William Enright

William Enright

Chief Executive Officer

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