Form 8-K

8-K — Xenetic Biosciences, Inc.

Accession: 0001683168-26-007181

Filed: 2026-09-16

Period: 2026-09-14

CIK: 0001534525

SIC: 2834 (PHARMACEUTICAL PREPARATIONS)

Item: Entry into a Material Definitive Agreement

Item: Unregistered Sales of Equity Securities

Item: Regulation FD Disclosure

Item: Financial Statements and Exhibits

Documents

8-K — xenetic_8k.htm (Primary)

EX-2.1 — SHARE EXCHANGE AGREEMENT (xenetic_ex0201.htm)

EX-10.1 (xenetic_ex1001.htm)

EX-10.2 (xenetic_ex1002.htm)

EX-10.3 (xenetic_ex1003.htm)

EX-99.1 — PRESS RELEASE (xenetic_ex9901.htm)

EX-99.2 — PRESENTATION (xenetic_ex9902.htm)

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UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

________________________

FORM 8-K

________________________

CURRENT REPORT

Pursuant to Section 13 or 15(d) of The

Securities Exchange Act of 1934

Date of Report (Date of earliest event

reported): September 14,

2026

________________________

Xenetic Biosciences,

Inc.

(Exact name of registrant as specified in charter)

Nevada

001-37937

45-2952962

(State or other jurisdiction

of incorporation)

(Commission

File Number)

(IRS Employer

Identification No.)

945

Concord Street

Framingham, Massachusetts

01701

(Address of principal executive offices)

(Zip Code)

(781) 778-7720

(Registrant’s telephone number, including

area code)

Not Applicable

(Former name or former address, if changed since

last report)

Check the appropriate box below if the

Form 8-K is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (see

General Instruction A.2. below):

☐ Written communications

pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

☒ Soliciting material

pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

☐ Pre-commencement

communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

☐ Pre-commencement

communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to Section 12(b)

of the Act:

Title of each class

Trading Symbol(s)

Name of each exchange on which registered

Common Stock, $0.001 par value per share

XBIO

The

Nasdaq Stock Market

Indicate by check mark whether the registrant

is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (17 CFR §230.405) or Rule 12b-2 of the Securities

Exchange Act of 1934 (17 CFR §240.12b-2).

Emerging growth company ☐

If an emerging growth company, indicate by check

mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting

standards provided pursuant to Section 13(a) of the Exchange Act. ☐

Item 1.01.

Entry into a Material Definitive Agreement.

Share Exchange Agreement

On September 14, 2026, Xenetic Biosciences, Inc.,

a Nevada corporation (“Xenetic” or the “Company”), entered into a Share Exchange Agreement (the “Exchange

Agreement”) with Santersus AG, a Swiss corporation (Aktiengesellschaft) (“Santersus”), the sellers listed on

Schedule I thereto (each, a “Seller,” and collectively with the holders of Santersus securities who subsequently become parties

to the Exchange Agreement, the “Sellers”) and Santersus, in its capacity as representative of the Sellers, pursuant to which,

subject to the satisfaction or waiver of the conditions set forth in the Exchange Agreement, Xenetic will acquire the entire issued share

capital of Santersus, with Santersus becoming a wholly owned subsidiary of Xenetic (the “Acquisition”). The Acquisition is

intended to constitute a tax-free reorganization within the meaning of Section 368(a) of the Internal Revenue Code of 1986, as amended.

Unless otherwise defined herein, the capitalized terms used below are defined in the Exchange Agreement.

At the closing of the Acquisition (the “Closing”),

each issued and outstanding ordinary share of Santersus (the “Santersus Shares”) will be sold to Xenetic in exchange for a

number of shares of Xenetic common stock, par value $0.001 per share (“Company Common Stock”), based on the exchange ratio

set forth in the Exchange Agreement (the “Exchange Ratio”) rounded to the nearest whole share of Company Common Stock after

aggregating all fractional shares of Company Common Stock issuable to each Seller (the “Acquisition Consideration”). No fractional

shares of Company Common Stock will be issued. At the Closing, each option to purchase Santersus ordinary shares that is outstanding and

unexercised immediately prior to the Closing, whether or not vested, will be converted into and become an option to purchase Company Common

Stock, and will be assumed by Xenetic in accordance with the Santersus Option Plan and the applicable option agreement, with the number

of shares and exercise price adjusted based on the Exchange Ratio. Xenetic will also assume the Santersus Option Plan solely with respect

to such options.

Immediately following the Closing, the holders

of Santersus Shares are expected to own approximately 85% of the outstanding shares of Company Common Stock, with existing Xenetic stockholders

owning the balance, on a fully diluted basis as calculated in the Exchange Agreement and assuming Net Cash of $0 at the Closing. The final

ownership percentages of the combined company that each party’s equity holders will own following the Closing is subject to certain

adjustments as described in the Exchange Agreement, including the Net Cash calculation. For purposes of the Exchange Agreement, “Santersus

Shares” include the issued and outstanding Santersus ordinary shares, the Santersus ordinary shares into which Santersus preferred

shares will convert immediately prior to the Closing, and any Santersus ordinary shares issued upon exercise of Santersus options at or

prior to the Closing. Santersus has also agreed to cause each person who acquires Santersus ordinary shares after the execution of the

Exchange Agreement, including through the conversion of Santersus preferred shares or the exercise of Santersus options, to become a party

to the Exchange Agreement by executing a joinder agreement.

In connection with the Acquisition, Xenetic will

prepare and file with the U.S. Securities and Exchange Commission (the “SEC”) a proxy statement (the “Proxy Statement”),

and mail the Proxy Statement to Xenetic stockholders, to seek the approval of Xenetic’s stockholders with respect to certain actions

related to the Acquisition (such matters related to the Acquisition, the “Company Stockholder Approval Matters”):

the issuance of the Acquisition Consideration and the change of control of Xenetic resulting from the Acquisition pursuant to applicable Nasdaq rules;

the amendment of Xenetic’s articles of incorporation to increase the number of authorized shares and to change Xenetic’s name to Santersus Bio, Inc. effective immediately following the Closing; and

the approval of any amendments to, or the adoption of, any option or warrant plans of Xenetic to give effect to the Acquisition.

The Proxy Statement will also seek the approval

of Xenetic’s stockholders with respect to certain actions related to Xenetic’s 2026 annual meeting of stockholders, including

the election of Xenetic’s director nominees to the Xenetic board of directors (the “Xenetic Board”); ratification of

the selection by Xenetic’s Audit Committee of CBIZ CPAs P.C. as the independent registered public accounting firm of Xenetic for

its fiscal year ending December 31, 2026; and the approval, by non-binding advisory vote, of a resolution approving the named executive

officer compensation.

Concurrently with the execution of the Exchange

Agreement, certain stockholders of Xenetic, including certain of its officers and directors, entered into voting and support agreements

(the “Company Voting Agreements”) in favor of Santersus and the Sellers, pursuant to which such stockholders agreed, among

other things, to vote their shares of Company Common Stock (i) in favor of the Company Stockholder Approval Matters, (ii) against any

proposal made in opposition to, or in competition with, the Exchange Agreement or the Acquisition and (iii) against any acquisition proposal

involving a third party. As of September 14, 2026, such stockholders held, in the aggregate, approximately 9.0% of the outstanding shares

of Company Common Stock.

The offer of the Company Common Stock to the Sellers

was made in reliance on an exemption from the registration provisions of the Securities Act of 1933, as amended (the “Securities

Act”), set forth in Section 4(a)(2) thereof and/or Regulation D promulgated thereunder, relating to sales by an issuer not involving

a public offering. The Sellers have each represented that it is an “accredited investor” as defined in Rule 501(a) of Regulation

D promulgated under the Securities Act. Concurrently with the filing of the Proxy Statement, Xenetic will prepare and file with the SEC

a resale registration statement on Form S-1 to register the resale of the shares of Company Common Stock to be issued in the Acquisition

(the “Registration Statement”).

The Exchange Agreement contains customary representations,

warranties and covenants of Xenetic and Santersus, including, among others, covenants that require each of Xenetic and Santersus to (i)

conduct its business in the ordinary course during the period between the execution of the Exchange Agreement and the Closing or earlier

termination of the Exchange Agreement, subject to certain exceptions, and (ii) not engage in certain kinds of transactions during such

period (without the prior written consent of the other). Subject to certain terms and conditions, the Xenetic Board, upon the recommendation

of its independent special committee, will recommend the approval of the Company Stockholder Approval Matters. Each of Xenetic and Santersus

have agreed not to (i) solicit proposals relating to alternative business combination transactions or (ii) subject to certain exceptions,

enter into discussions or negotiations or provide confidential information in connection with any proposals for alternative business combination

transactions.

Completion of the Acquisition is subject to a

number of conditions, including (i) approval by Xenetic’s stockholders of the Company Stockholder Approval Matters; (ii) the effectiveness

of the Registration Statement and the absence of any related stop order; (iii) approval of the shares of Company Common Stock to be issued

in the Acquisition for listing on Nasdaq, subject to official notice of issuance and consummation of the transactions contemplated by

the Exchange Agreement; (iv) the accuracy of the representations and warranties, subject to certain materiality qualification, (v) compliance

by the parties with their respective covenants, (vi) no law or order preventing the Acquisition and related transactions, and (vii) certain

other customary closing conditions. The Exchange Agreement contains certain termination rights for both Xenetic and Santersus, and further

provides that upon termination of the Exchange Agreement under specified circumstances, Xenetic may be required to pay Santersus a termination

fee of $500,000. In addition, under certain conditions, Xenetic and Santersus may each be required to reimburse the other party for fees

and expenses up to $300,000.

Governance

Following the Closing, it is expected that the

board of directors of the combined company will consist of eight members, two of whom will be designated by Xenetic and six of whom will

be designated by Santersus, with the chairman of the board to be designated by Santersus. Following the Closing, the Company will change

its name to Santersus Bio, Inc. and it is expected that shares of common stock of the combined company will be listed on the Nasdaq Capital

Market under the symbol “SNTS.”

Lock-Up Agreements

Concurrently with the execution of the Exchange

Agreement, certain officers, directors and stockholders of Xenetic and Santersus entered into lock-up agreements (collectively, the “Lock-Up

Agreements”), pursuant to which such parties agreed, among other things, to not sell or transfer their shares of post-Closing Company

Common Stock for a 180-day period following the Closing, other than certain limited exceptions.

The foregoing summary descriptions of the Exchange

Agreement, Company Voting Agreements, and Lock-Up Agreements do not purport to be complete and are subject to and qualified in their entirety

by reference to the Exchange Agreement, the form of Company Voting Agreements, the form of Company Lock-Up Agreement and the form of Santersus

Lock-Up Agreement, copies of which are attached hereto as Exhibits 2.1, 10.1, 10.2 and 10.3 respectively, and the terms of which are incorporated

herein by reference.

The Exchange Agreement, Company Voting Agreements

and Lock-Up Agreements (collectively, the “Transaction Agreements”) have been included as exhibits to this Current Report

on Form 8-K to provide investors and security holders with information regarding their respective terms. They are not intended to provide

any other financial information about the respective parties thereto or their respective subsidiaries or affiliates. The representations,

warranties and covenants contained in the Transaction Agreements were made only for purposes of those agreements and as of specific dates;

were solely for the benefit of the parties thereto; may be subject to limitations agreed upon by such parties, including being qualified

by confidential disclosures made for the purposes of allocating contractual risk between the parties thereto instead of establishing these

matters as facts; and may be subject to standards of materiality applicable to the contracting parties that differ from those applicable

to investors. Investors should not rely on the representations, warranties and covenants or any description thereof as characterizations

of the actual state of facts or condition of the parties to the Transaction Agreements or any of their respective subsidiaries or affiliates.

Moreover, information concerning the subject matter of the representations, warranties and covenants may change after the date of the

Transaction Agreements, which subsequent information may or may not be fully reflected in public disclosures by the parties thereto.

Item 3.02. Unregistered Sales of Equity Securities.

The disclosure contained in Item 1.01 above is hereby incorporated into this Item 3.02 by reference.

Item 7.01. Regulation FD Disclosure.

Attached as Exhibit 99.1 is a copy of the joint press release issued

by Xenetic and Santersus on September 16, 2026 announcing the execution of the Exchange Agreement. Xenetic and Santersus will host a joint

conference call and webcast on September 16, 2026 at 8:30 a.m. Eastern Time to discuss the proposed Acquisition. A copy of the slide presentation

to be used during the joint conference call is attached hereto as Exhibit 99.2.

The information in this Item 7.01, including Exhibits

99.1 and 99.2 attached hereto, is being furnished, shall not be deemed “filed” for any purpose, and shall not be deemed incorporated

by reference in any filing under the Securities Act, or the Securities Exchange Act of 1934, as amended, except as expressly set forth

by specific reference in such a filing.

Additional Information and Where to Find It

This communication relates to the proposed acquisition

transaction involving Xenetic and Santersus and may be deemed to be solicitation material in respect of the Acquisition. In connection

with the Acquisition, Xenetic will file with the SEC a Proxy Statement and Registration Statement on Form S-1. Each party may also file

other documents regarding the Acquisition with the SEC. INVESTORS AND SECURITY HOLDERS ARE URGED TO READ CAREFULLY THE PROXY STATEMENT,

REGISTRATION STATEMENT ON FORM S-1, AND OTHER RELEVANT DOCUMENTS FILED OR WILL BE FILED WITH THE SEC, AS WELL AS ANY AMENDMENTS OR SUPPLEMENTS

THERETO AND ANY DOCUMENTS INCORPORATED BY REFERENCE THEREIN, IN THEIR ENTIRETY IF AND WHEN THEY BECOME AVAILABLE BECAUSE THEY CONTAIN

OR WILL CONTAIN IMPORTANT INFORMATION ABOUT THE ACQUISITION, RELATED MATTERS AND THE PARTIES TO THE ACQUISITION. Investors and security

holders may obtain a free copy of the Proxy Statement, the Registration Statement on Form S-1, and other relevant documents (if and when

they become available) that are or will be filed with the SEC for free at the SEC’s website at www.sec.gov. Copies of the documents

(when they become available) filed with the SEC by Xenetic Biosciences will be available free of charge on Xenetic’s website at

http://xeneticbio.com.

Participants in the Solicitation

Xenetic, and its directors and executive officers,

and Santersus, and its directors and officers, may be deemed to be participants in the solicitation of proxies from the stockholders of

Xenetic in connection with the Acquisition under the rules of the SEC. Information about the interests of these directors and executive

officers and other persons who may be deemed to be participants in the solicitation of stockholders of Xenetic in connection with the

Acquisition and a description of their direct and indirect interests, by security holdings or otherwise, will be included in the Proxy

Statement related to the Acquisition, which will be filed with the SEC. Additional information about Xenetic, the directors and executive

officers of Xenetic and their ownership of Xenetic common stock can also be found in its Annual Report on Form 10-K for the year ended

December 31, 2025, as filed with the SEC on March 12, 2026, and amended on April 24, 2026, and its definitive proxy statement, as filed

with the SEC on October 31, 2025, and other documents subsequently filed by Xenetic with the SEC. Free copies of these documents may be

obtained as described above. To the extent holdings of Xenetic securities by its directors or executive officers have changed since the

amounts set forth in such documents, such changes have been or are expected to be reflected on Initial Statements of Beneficial Ownership

on Form 3 or Statements of Beneficial Ownership on Form 4 filed with the SEC. Additional information regarding the identity of potential

participants, and their direct or indirect interests, by security holdings or otherwise, will be included in the Proxy Statement relating

to the Acquisition when it is filed with the SEC.

No Offer or Solicitation

This Current Report on Form 8-K is for informational

purposes only. This communication shall not constitute an offer to subscribe for, buy or sell or the solicitation of an offer to subscribe

for, buy or sell any securities, or a solicitation of any vote or approval, nor shall there be any sale of, or offer to sell or buy, securities

in any jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities

laws of any such jurisdiction. This communication is for informational purposes only. No offering of securities shall be made, except

by means of a prospectus meeting the requirements of Section 10 of the U.S. Securities Act, and otherwise in accordance with applicable

law.

Forward-Looking Statements

This Current Report on Form 8-K, including the

press release, contains “forward-looking statements” within the meaning of the “safe harbor” provisions of the

Private Securities Litigation Reform Act of 1995, including but not limited to, express or implied statements regarding the structure,

timing and completion of the Acquisition; the combined company’s listing on Nasdaq after closing of the Acquisition; expectations

regarding the ownership structure of the combined company; the anticipated timing of closing; the future operations of the combined company;

the nature, strategy and focus of the combined company; the development and commercial potential and potential benefits of NucleoCapture

and Xenetic’s DNase technology; anticipated clinical drug development activities and related timelines, including the expected timing

for data and other clinical results; the competitive landscape of the combined company; the expected board composition of the combined

company; and other statements that are not historical fact. All statements other than statements of historical fact contained in this

communication are forward-looking statements. These forward-looking statements are made as of the date they were first issued, and were

based on the then-current expectations, estimates, forecasts, and projections, as well as the beliefs and assumptions of management. Forward-looking

statements are subject to a number of risks and uncertainties, many of which involve factors or circumstances that are beyond Xenetic,

Santersus or the combined company’s control. Actual results could differ materially from those stated or implied in forward-looking

statements due to a number of factors, including but not limited to (i) the risk that the conditions to the closing of the Acquisition

are not satisfied, including the failure to timely obtain stockholder approval for the transaction, if at all; (ii) uncertainties as to

the timing of the consummation of the Acquisition and the ability of each of Xenetic and Santersus to consummate the Acquisition; (iii)

risks related to each parties’ ability to manage its operating expenses and its expenses associated with the Acquisition pending

closing; (iv) risks related to the failure or delay in obtaining required approvals from any governmental or quasi-governmental entity

necessary to consummate the Acquisition; (v) the risk that as a result of adjustments to the exchange ratio, Xenetic stockholders and

Santersus stockholders could own more or less of the combined company than is currently anticipated; (vi) risks related to the market

price of Xenetic common stock relative to the value suggested by the exchange ratio; (vii) unexpected costs, charges or expenses resulting

from the Acquisition; (viii) potential adverse reactions or changes to business relationships resulting from the announcement or completion

of the Acquisition; (ix) the uncertainties associated with Xenetic platform technologies, as well as risks associated with the clinical

development and regulatory approval of product candidates, including potential delays in the commencement, enrollment and completion of

clinical trials; (x) risks related to the inability of the combined company to obtain sufficient additional capital to continue to advance

these product candidates and its clinical programs; (xi) uncertainties in obtaining successful clinical results for product candidates

and unexpected costs that may result therefrom; (xii) risks related to the failure to realize any value from product candidates being

developed and anticipated to be developed in light of inherent risks and difficulties involved in successfully bringing product candidates

to market; (xiii) risks associated with the possible failure to realize certain anticipated benefits of the Acquisition, including with

respect to future financial and operating results, (xiv) risks related to the inability of the combined company to maintain compliance

with Nasdaq listing requirements following Closing, and the potential need for the combined company to effect a reverse stock split of

the Company Common Stock in order to satisfy Nasdaq listing requirements; (xv) risks related to the combined company raising additional

working capital and financing its business; and (xvi) the other factors discussed under the heading “Risk Factors” in Xenetic’s

most recent Annual Report on Form 10-K and other filings with the SEC, among others. Actual results and the timing of events could differ

materially from those anticipated in such forward-looking statements as a result of these risks and uncertainties. These and other risks

and uncertainties are more fully described in filings that Xenetic makes and will make with the SEC in connection with the Acquisition,

including Xenetic’s Proxy Statement described above under “Additional Information and Where to Find It.” You should

not place undue reliance on these forward-looking statements, which are made only as of the date hereof or as of the dates indicated in

the forward-looking statements. Xenetic, Santersus and the combined company expressly disclaims any obligation or undertaking to release

publicly any updates or revisions to any forward-looking statements contained herein to reflect any change in its expectations with regard

thereto or any change in events, conditions or circumstances on which any such statements are based.

Item 9.01.

Financial Statements and Exhibits.

(d) Exhibits.

Exhibit No.

Description

2.1

Share Exchange Agreement, dated as of September 14, 2026, by and among Xenetic Biosciences, Inc., Santersus AG, the Sellers listed on Schedule I thereto and Santersus AG, as Representative of the Sellers.*

10.1

Form of Company Voting Agreement.

10.2

Form of Company Lock-Up Agreement.

10.3

Form of Santersus Lock-Up Agreement.

99.1

Joint Press Release, dated September 16, 2026.

99.2

Presentation.

104

Cover Page Interactive Data File (embedded within the Inline XBRL document).

* Exhibits and schedules have been omitted pursuant to

Item 601(a)(5) of Regulation S-K. Xenetic hereby undertakes to furnish supplementally copies of any of the omitted exhibits or schedules

upon request by the SEC.

SIGNATURES

Pursuant to the requirements

of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto

duly authorized.

XENETIC BIOSCIENCES, INC.

By:

/s/ James Parslow

Date: September 16, 2026

Name:

James Parslow

Title:

Interim Chief Executive Officer and Chief Financial Officer

EX-2.1 — SHARE EXCHANGE AGREEMENT

EX-2.1

Filename: xenetic_ex0201.htm · Sequence: 2

Exhibit 2.1

______________________________________________________________________________

SHARE EXCHANGE AGREEMENT

BY AND AMONG

XENETIC BIOSCIENCES, INC.,

SANTERSUS AG,

THE SELLERS LISTED ON SCHEDULE I HERETO, AND

THE SELLER REPRESENTATIVE

Dated as of September 14, 2026

TABLE OF CONTENTS

Page

Article 1 THE ACQUISITION

1.1 The Acquisition

1.2 Closing

1.3 Company Name Change

1.4 Santersus Securities

1.5 Calculation of Net Cash

1.6 Consents and Associated Acknowledgments of Sellers; Seller Representative

1.7 Delivery of Acquisition Consideration

1.8 No Further Rights

1.9 Additional Actions

Article 2 REPRESENTATIONS AND WARRANTIES OF SANTERSUS

2.1 Organization and Qualification; Charter Documents

2.2 Capital Structure

2.3 Authority; Non-Contravention; Approvals

2.4 Santersus Financial Statements; No Undisclosed Liabilities

2.5 Absence of Certain Changes or Events

2.6 Taxes

2.7 Intellectual Property

2.8 Data Privacy

2.9 Compliance with Legal Requirements

2.10 Scientific Studies

2.11 Legal Proceedings; Orders

2.12 Brokers’ and Finders’ Fees

2.13 Employee Benefit Plans

2.14 Title to Assets; Real Property

2.15 Environmental Matters

2.16 Labor Matters

2.17 Santersus Contracts

2.18 Insurance

2.19 Interested Party Transactions

2.20 Disclosure; Company Information

2.21 Anti-Takeover Statutes Not Applicable

2.22 Ownership of Company Common Stock

2.23 Exclusivity of Representations; Reliance

Article 3 REPRESENTATIONS AND WARRANTIES OF COMPANY

3.1 Organization and Qualification; Charter Documents

3.2 Capital Structure

3.3 Authority; Non-Contravention; Approvals

3.4 Anti-Takeover Statutes

3.5 SEC Filings; Company Financial Statements; No Undisclosed Liabilities

3.6 Absence of Certain Changes or Events

3.7 Taxes

3.8 Intellectual Property

3.9 Data Privacy

3.10 Compliance with Legal Requirements

3.11 Legal Proceedings; Orders

3.12 Brokers’ and Finders’ Fees

3.13 Employee Benefit Plans

3.14 Title to Assets; Real Property

3.15 Environmental Matters

3.16 Labor Matters

3.17 Company Contracts

3.18 Insurance

3.19 Code of Ethics

3.20 Opinion of Financial Advisor

3.21 Interested Party Transactions

3.22 Valid Issuance

3.23 No TID U.S. Business

3.24 Disclosure; Company Information

3.25 Exclusivity of Representations; Reliance

Article 4 REPRESENTATIONS AND WARRANTIES OF SELLERS

4.1 Ownership of Santersus Share Capital

4.2 Authority; Non-Contravention

4.3 Tax Matters

4.4 Disclosure; Seller Information

4.5 Ownership of Company Stock; Affiliates

4.6 Securities Law Matters.

4.7 No Brokers

4.8 Exclusivity of Representations; Reliance

Article 5 CONDUCT OF BUSINESS PENDING THE CLOSING

5.1 Conduct of Company Business

5.2 Conduct of Santersus Business

Article 6 ADDITIONAL AGREEMENTS

6.1 Registration Statement; Proxy Statement

6.2 Company Stockholders’ Meeting; Company Board Recommendation

6.3 Access to Information; Confidentiality

6.4 Regulatory Approvals and Related Matters

6.5 Director Indemnification and Insurance

6.6 Notification of Certain Matters

6.7 Public Announcements

6.8 Conveyance Taxes

6.9 Board of Directors and Officers

6.10 Non-Solicitation by Company and Santersus

6.11 Restrictions on Transfer

6.12 Joinder Agreements

6.13 Listing; Symbol

6.14 Section 16 Compliance

6.15 Santersus Options/ Option Plan

6.16 Allocation Certificate

6.17 Employee Matters

6.18 Disclosure Schedules

6.19 Tax Matters

6.20 Reverse Stock Split.

6.21 Stockholder Litigation

6.22 Termination of Contracts

6.23 No Trading

iii

6.24 Continuation of the Business

Article 7 CONDITIONS TO THE CLOSING

7.1 Conditions to Obligation of Each Party to Effect the Acquisition

7.2 Additional Conditions to Obligations of Santersus and Sellers

7.3 Additional Conditions to Obligations of Company

7.4 Frustration of Closing Conditions

Article 8 TERMINATION

8.1 Termination

8.2 Effect of Termination

8.3 Expenses; Termination Fees

Article 9 GENERAL PROVISIONS

9.1 Notices

9.2 Amendment

9.3 Headings

9.4 Severability

9.5 Entire Agreement

9.6 Successors and Assigns

9.7 Parties in Interest

9.8 Waiver

9.9 Remedies Cumulative; Specific Performance

9.10 Governing Law; Venue; Waiver of Jury Trial

9.11 Counterparts and Exchanges by Electronic Transmission or Facsimile

9.12 Attorney Fees

9.13 Cooperation

9.14 Limited Survival of Representations and Warranties

9.15 Construction

9.16 Release and Covenant Not to Sue

Exhibits

Exhibit A

Certain Definitions

Exhibit B

Form of Company Lock-Up Agreement

Exhibit C

Form of Santersus Lock-Up Agreement

Exhibit D

Form of Company Voting Agreement

Exhibit E

Form of Joinder Agreement

Exhibit F

Sample Net Cash Calculation

Exhibit G

Sample Exchange Ratio Calculation

Schedules

Schedule I

Sellers

Schedule II

Company Lock-Up Agreement Parties

Schedule III

Santersus Lock-Up Agreement Parties

Schedule IV

Company Voting Agreement Parties

Schedule 6.22

Termination of Santersus Contracts

Company Disclosure Schedule

Santersus Disclosure Schedule

SHARE EXCHANGE AGREEMENT

THIS SHARE EXCHANGE AGREEMENT

is made and entered into as of September 14, 2026 (this “Agreement”) by and among Xenetic Biosciences, Inc.,

a Nevada corporation (“Company”), Santersus AG, a Swiss corporation (Aktiengesellschaft) (“Santersus”),

the Persons listed on Schedule I hereto (including each Person, if any, who executes a Joinder Agreement as contemplated

by Sections 6.11 and 6.12) (“Sellers”), and Santersus, as representative of the Sellers (the “Seller

Representative”). Santersus, Company and each Seller are each a “Party” and referred to collectively

herein as the “Parties.” Certain capitalized terms used in this Agreement are defined in Exhibit A.

RECITALS

WHEREAS, Sellers own,

as of the date hereof, all of the Santersus Issued Share Capital;

WHEREAS, Sellers desire

to sell to Company, and Company desires to purchase from Sellers, all of the issued and outstanding Santersus Shares in exchange for shares

of Company Common Stock, with the result of Santersus becoming a wholly-owned Subsidiary of Company, in each case on the terms and conditions

set forth herein;

WHEREAS, the board

of directors of Santersus has determined that this Agreement and the Contemplated Transactions to which Santersus is or will be a party

are in the best interests of Santersus and has approved and declared advisable this Agreement and the Contemplated Transactions to which

Santersus is or will be a party;

WHEREAS, the special

committee of the board of directors of Company (the “Special Committee”) (i) has determined that this Agreement

and the Contemplated Transactions to which the Company is or will be a party are fair to, and in the best interests of, Company and its

stockholders, (ii) has approved, adopted and declared advisable this Agreement and the Contemplated Transactions to which the Company

is or will be a party and (iii) has determined to recommend that the Company Stockholders vote to approve the Company Stockholder Approval

Matters;

WHEREAS, prior to the

Closing, all of the Santersus Preferred Shares shall be converted (the “Santersus Share Conversion”) into Santersus

Ordinary Shares (collectively, the “Santersus Conversion Shares”); and

WHEREAS, as a condition

to the willingness of Santersus and the Sellers to enter into this Agreement, contemporaneously with the execution and delivery of this

Agreement, each of the Persons listed on Schedule II (each, a “Company Lock-Up Party”) is entering

into a lock-up agreement in substantially the form of Exhibit B attached hereto (the “Company Lock-Up Agreements”);

WHEREAS, as a condition

to the willingness of the Company to enter into this Agreement, contemporaneously with the execution and delivery of this Agreement, each

of the Persons listed on Schedule III (each, a “Santersus Lock-Up Party”) is entering into a lock-up

agreement in substantially the form of Exhibit C attached hereto (the “Santersus Lock-Up Agreements”);

and

WHEREAS, as a condition

to the willingness of Santersus and Sellers to enter into this Agreement, concurrently with the execution and delivery of this Agreement,

certain stockholders of Company listed on Schedule IV are entering into voting and support agreements in substantially the

form of Exhibit D attached hereto (the “Company Voting Agreements”), in favor of Santersus and

Sellers, pursuant to which such stockholders have agreed, among other things, to vote their shares of Company Common Stock in favor of

the Company Stockholder Approval Matters.

AGREEMENT:

NOW, THEREFORE,

in consideration of the foregoing and the representations, warranties and covenants herein contained, and for other good and valuable

consideration, the receipt, adequacy and sufficiency of which are hereby acknowledged, the Parties, intending to be legally bound, hereby

agree as follows:

Article

THE ACQUISITION

1.1

The Acquisition. Upon the terms and subject to the conditions of this Agreement, at the Closing, each Seller shall sell,

transfer and convey to Company, and Company shall purchase, acquire, assume and accept from each Seller, all right, title and interest

in and to all of the Santersus Shares owned by such Seller as set forth opposite to his/her/its name in Part 4.1 of the Santersus

Disclosure Schedule and any Santersus Shares acquired by such Seller prior to Closing, as set forth opposite to his/her/its name in the

Santersus Allocation Certificate, free and clear of all Encumbrances. The Santersus Shares shall be sold with all rights attaching to

them at Closing or subsequently, including the rights to receive all dividends and other distributions declared, made or paid on Santersus

Shares after Closing. Company shall not be obliged to complete the purchase and sale of the Santersus Shares unless the purchase and sale

of all the Santersus Shares is completed simultaneously. Each Seller hereby waives any rights of preemption or other restrictions on transfer

in respect of the Santersus Shares, whether conferred by the Organizational Documents of Santersus or otherwise, in respect of the transfers

of the Santersus Shares contemplated by this Agreement and approves such transfer for the purposes of the Organizational Documents of

Santersus. The purchase and sale of the Santersus Shares pursuant to this Agreement is referred to herein as the “Acquisition.”

1.2

Closing. Unless this Agreement has been terminated and the Contemplated Transactions have been abandoned pursuant to

Section 8.1, and subject to the satisfaction or waiver of the conditions set forth in Article 7, the consummation of the

Acquisition (the “Closing”) will take place by electronic exchange of the various documents to be delivered

hereunder, as soon as possible (but in any event no later than two (2) Business Days) after satisfaction or waiver of the conditions set

forth in Article 7 (other than those conditions that by their nature are to be satisfied at the Closing, but subject to the satisfaction

or waiver of each such condition), or at such other time, date and place as Santersus and Company may mutually agree in writing. The date

on which the Closing actually takes place is referred to as the “Closing Date.”

1.3

Company Name Change. Unless otherwise determined by Santersus, Company and Santersus will take any and all action necessary

to change Company’s name to “Santersus Bio, Inc.” effective immediately following the Closing.

1.4

Santersus Securities.

(a)

Santersus Shares. Each Santersus Share issued and outstanding immediately prior to the Closing will be sold to Company

by the Seller that owns such Santersus Share in consideration for such number of duly authorized, validly issued, fully paid and non-assessable

shares of Company Common Stock as is equal to the Exchange Ratio, rounded to the nearest whole share of Company Common Stock (after aggregating

all fractional shares of Company Common Stock issuable to such Seller) (the “Acquisition Consideration”).

(b)

Santersus Options. Each Santersus Option that is outstanding and unexercised immediately prior to the Closing will

be treated in accordance with Section 6.15.

(c)

Adjustments to Exchange Ratio. The Exchange Ratio will be calculated in the manner described in the definition of

“Exchange Ratio” on Exhibit A hereto and will be appropriately adjusted to reflect fully the effect of any stock

split, reverse split, stock dividend (including any dividend or distribution of securities convertible into Santersus Share Capital or

Company Common Stock), reorganization, recapitalization or other like change with respect to the Santersus Share Capital or Company Common

Stock occurring after the date hereof and prior to the Closing.

(d)

No Fractional Shares. No fractional shares of Company Common Stock will be issued in connection with the Acquisition,

and no certificates or scrip for any such fractional shares of Company Common Stock will be issued. Sellers will not be entitled to any

voting rights, rights to receive any dividends or distributions or other rights as a stockholder of Company with respect to any such fractional

shares of Company Common Stock that would have otherwise been issued to such Seller.

(e)

Santersus Share Conversion. Conditional upon the Closing, each Seller hereby irrevocably agrees to the Santersus

Share Conversion upon the terms described herein, which shall be deemed to occur immediately prior to the Closing.

1.5

Calculation of Net Cash.

(a)

At least fifteen (15) calendar days prior to the anticipated Closing Date (the “Anticipated Closing Date”),

Company will deliver to Santersus a schedule (the “Net Cash Schedule”) setting forth, in reasonable detail,

Company’s good faith, estimated calculation of Net Cash (the “Net Cash Calculation” and the date of delivery

of such schedule, the “Delivery Date”) as of the Anticipated Closing Date (the “Cash Determination

Time”) prepared and certified by Company’s Chief Financial Officer (or if there is no Chief Financial Officer, the

principal accounting officer for Company). Company shall make available to Santersus, as requested by Santersus, the work papers and back-up

materials used in or reasonably relevant to the preparation of the Net Cash Schedule (subject to Santersus’ execution of customary

access letters) and, if reasonably requested by Santersus, Company’s accountants and counsel at reasonable times and upon reasonable

advance notice.

(b)

Within three (3) calendar days after the Delivery Date (the last day of such period, the “Response Date”),

Santersus shall have the right to dispute any part of the Net Cash Calculation by delivering a written notice to that effect to Company

(a “Dispute Notice”). Any Dispute Notice shall identify in reasonable detail and to the extent known the nature

and amounts of any proposed revisions to the Net Cash Calculation Santersus reasonably believes to be necessary and appropriate.

(c)

If, on or prior to the Response Date, Santersus notifies Company in writing that it has no objections to the Net Cash Calculation

or, if Santersus fails to deliver a Dispute Notice as provided in Section 1.5(b) by 11:59 p.m. Eastern Time on the Response Date,

then the Net Cash Calculation as set forth in the Net Cash Schedule shall be deemed to have been finally determined for purposes of this

Agreement and to represent the Net Cash at the Cash Determination Time for all purposes under this Agreement.

(d)

If Santersus timely delivers a Dispute Notice to Company, then Representatives of Company and Santersus shall promptly meet and

attempt in good faith to resolve any disputes between them regarding the Net Cash Calculation and negotiate an agreed-upon determination

of Net Cash, which agreed upon Net Cash amount shall be deemed to have been finally determined for purposes of this Agreement and to represent

the Net Cash at the Cash Determination Time for all purposes under this Agreement.

(e)

If Representatives of Company and Santersus are unable to negotiate an agreed-upon determination of Net Cash as of the Cash Determination

Time pursuant to Section 1.5(d) within three (3) calendar days after delivery of the Dispute Notice (or such other period as Company

and Santersus may mutually agree upon), then any remaining matters in dispute regarding the calculation of Net Cash shall be referred

to Baker Tilly US, LLP (the “Accounting Firm”). At the Accounting Firm’s request, (i) Company shall promptly

make available or deliver to the Accounting Firm such work papers and back-up materials used by Company in preparing the Net Cash Schedule

as the Accounting Firm reasonably requests and (ii) Santersus shall promptly make available or deliver to the Accounting Firm such work

papers and back-up materials used by Santersus in disputing Company’s Net Cash Calculation as the Accounting Firm reasonably requests,

and Company and Santersus shall use commercially reasonable efforts to cause the Accounting Firm to resolve all remaining matters in dispute

within five (5) Business Days of accepting its selection. Company and Santersus shall be afforded the opportunity to present to the Accounting

Firm any material related to all matters in dispute and to discuss the basis for such dispute with the Accounting Firm; provided,

however, that no such presentation or discussion shall occur without the presence of a Representative of each of Company and Santersus.

The determination of the Accounting Firm shall be limited to the matters in dispute submitted to the Accounting Firm for final determination.

The Accounting Firm shall act as an expert and not as an arbitrator and shall be instructed to resolve only such matters relating to the

calculation of Net Cash as are then in dispute. The resolution of the matters in dispute made by the Accounting Firm and the resulting

calculation of the amount of Net Cash giving effect to such resolution shall be made in writing and delivered to each of Company and Santersus,

shall be final and binding on Company and Santersus and shall be deemed to have been finally determined for purposes of this Agreement

and to represent the Net Cash at the Cash Determination Time for all purposes under this Agreement. The Parties shall delay the Closing

until the resolution of the matters described in this Section 1.5(e). The fees and expenses of the Accounting Firm shall be allocated

between Company and Santersus in the same proportion that the amount of the matters in dispute that were unsuccessfully disputed by such

Party (as finally determined by the Accounting Firm) bears to the total amount of all disputed matters resolved by the Accounting Firm.

For example, if Company claims the Net Cash is $1,000 greater than the amount determined by Santersus, and Santersus contests only $500

of the amount claimed by Company, and if the Accounting Firm ultimately resolves the dispute by awarding Company $300 of the $500 contested,

then the costs and expenses of the Accounting Firm will be allocated 60% (i.e., 300 ÷ 500) to Santersus and 40% (i.e., 200 ÷

500) to Company. If this Section 1.5(e) applies as to the determination of the Net Cash at the Cash Determination Time described

in Section 1.5(a), upon resolution of the matters in dispute in accordance with this Section 1.5(e), the Parties shall not

be required to determine Net Cash again even though the Closing Date may occur later than the Anticipated Closing Date, except that either

Company or Santersus may request a redetermination of Net Cash (using the principles established by the Accounting Firm in resolving the

matters in dispute pursuant to this Section 1.5(e)) if the Closing Date is more than seven (7) calendar days after the Anticipated

Closing Date.

1.6

Consents and Associated Acknowledgments of Sellers; Seller Representative.

(a)

Consents of Sellers. Each Seller (including, for the avoidance of doubt, any Person who becomes a Seller by execution of

a Joinder Agreement after the date hereof) hereby, on a several and not joint basis with the other Sellers:

(i)

consents and agrees for the purpose of each applicable provision of the Organizational Documents of Santersus, applicable laws

and otherwise, to the adoption by the general assembly of the shareholders of Santersus of amended and restated Articles of Incorporation

of Santersus (the “Santersus A&R Articles of Incorporation”), in a form reasonably acceptable to the Company;

(ii)

waives any notice with respect to the Acquisition, this Agreement and the Transaction Documents and the transactions contemplated

hereby and thereby, to which such Seller may be entitled pursuant to the Organization Documents, Shareholders’ Agreement, or any

other agreement by and between Santersus and such Seller, or any and all notices to which such Seller may be entitled pursuant to applicable

law or otherwise;

(iii) irrevocably waives

any rights relating to first offer, first refusal, first negotiation, redemption, information, participation and all other quasi-shareholder

or investor rights or privileges contained in any of the agreements set forth on Schedule 6.22 hereto, which such Seller may have

or may have had at any time, including but not limited to with respect to the Acquisition or any other transactions contemplated by this

Agreement, in each case, other than the right for payment for such Seller’s respective portion of the Acquisition Consideration

pursuant to, and subject to, the terms and conditions of this Agreement;

(iv) that, notwithstanding

the terms thereof, if and to the extent such Seller is a party to any of the agreements set forth on Schedule 6.22 hereto, such

Seller hereby agrees that, effective as of immediately prior to, and contingent upon the consummation of, the Closing, each of the agreements

set forth on Schedule 6.22 hereto to which such Seller is a party shall, in accordance with its respective terms, be terminated

and be of no further force or effect, and the officers of Santersus, each with the full power to act alone, be, and each hereby is, authorized,

directed and empowered, in the name of and on behalf of Santersus, to effect such terminations; and

(v) consents and agrees for the purpose

of each applicable provision of the Organizational Documents of Santersus, applicable laws and otherwise, to the approval of the Santersus

Share Conversion by the general assembly of the shareholders of Santersus.

(b)

Seller Representative.

(i)

Sellers (including, for the avoidance of doubt, any Person who becomes a Seller by execution of a Joinder Agreement after the date

hereof) hereby, on a several and not joint basis, irrevocably constitute and appoint the Seller Representative as their agent and attorney

in fact with full power of substitution to act from and after the date hereof and to do any and all things and execute any and all documents

on behalf of any Seller that may be necessary, convenient or appropriate to facilitate the consummation of the Acquisition, including,

but not limited to: (A) execution of documents and certificates (including any necessary wet-ink signatures) pursuant to this Agreement

and the Ancillary Agreements, including any Share Assignment Declaration; (B) receipt of payments under or pursuant to this Agreement

and the Ancillary Agreements and disbursement thereof to the Sellers and others, in accordance with this Agreement and the Ancillary Agreements

and subject to the terms hereof or thereof; (C) receipt and forwarding of notices and communications pursuant to this Agreement and

the Ancillary Agreements; (D) administration of the provisions of this Agreement and the Ancillary Agreements; (E) giving or

agreeing to, on behalf of the Sellers, any and all consents, waivers, amendments or modifications deemed by the Seller Representative,

in its sole and absolute discretion, to be necessary or appropriate under this Agreement or the Ancillary Agreements and the execution

(including any necessary wet-ink signatures) or delivery of any documents that may be necessary or appropriate in connection therewith;

(F) amending this Agreement, the Ancillary Agreements or any of the instruments to be delivered to Company pursuant to this Agreement

or the Ancillary Agreements; (G) (1) dispute or refrain from disputing, on behalf of each Seller relative to any amounts to

be received by such Seller under this Agreement or the Ancillary Agreements or any claim made by Company under this Agreement or the Ancillary

Agreements, (2) negotiate and compromise, on behalf of each Seller, any dispute that may arise under, and exercise or refrain from

exercising any remedies available under, this Agreement or the Ancillary Agreements and (3) execute, on behalf of such Seller, any

settlement agreement, release or other document with respect to such dispute or remedy; (H) engaging attorneys, accountants, agents

or consultants on behalf of the Sellers in connection with this Agreement or the Ancillary Agreements and paying any fees related thereto;

and (I) taking actions that are either (1) necessary or appropriate in the judgment of the Seller Representative for the accomplishment

of the foregoing or (2) expressly authorized or permitted to take pursuant to the other provisions of this Agreement and the Ancillary

Agreements.

(ii)

Company shall be fully protected in dealing with the Seller Representative under this Agreement and may conclusively rely upon

the authority of the Seller Representative to act on behalf of the Sellers without further evidence or investigation of any kind whatsoever.

Notices or communications to or from the Seller Representative shall constitute notice to or from each of the Sellers. Any decision or

action by the Seller Representative under this Agreement or the Ancillary Agreements shall constitute a decision or action of all Sellers

and shall be final, binding and conclusive upon each such Seller, and no Seller shall have the right to object to, dissent from, protest

or otherwise contest such decision or action. The appointment of the Seller Representative is coupled with an interest and shall be, to

the extent permissible by applicable Legal Requirements, irrevocable by any Seller in any manner or for any reason. This power of attorney

shall not be, to the extent permissible by applicable Legal Requirements, affected by death, illness, dissolution, disability, incapacity

or other inability to act of the principal pursuant to any applicable Legal Requirements. Each Seller shall severally, but not jointly,

indemnify and hold harmless, the Seller Representative from any and all losses, liabilities and expenses (including the reasonable fees

and expenses of counsel) arising out of or in connection with the Seller Representative’s execution and performance (solely in its

capacity as the representative of the Sellers and not in its capacity as a Seller, to the extent applicable) of this Agreement. The Sellers

acknowledge and agree that the foregoing indemnities shall survive the Closing, the resignation or removal of the Seller Representative

or the termination of this Agreement.

(c)

Santersus Share Conversion. Each of the Sellers who are holders of Santersus Preferred Shares, on a several and not joint

basis, hereby consent and agree to the conversion of all of their Santersus Preferred Shares into Santersus Ordinary Shares prior to the

Closing in accordance with the terms of this Agreement and such agreement shall hereby be deemed to constitute acknowledgement and agreement

that the Santersus Share Conversion will take effect immediately prior to Closing in accordance with this Agreement.

1.7

Delivery of Acquisition Consideration.

(a) Exchange Agent.

On or prior to the Closing Date, Company will select Empire Stock Transfer Inc. or another reputable bank or trust company reasonably

acceptable to Santersus to act as exchange agent in connection with the Acquisition and the other Contemplated Transactions (the “Exchange

Agent”) and shall execute an agreement with the Exchange Agent (the “Exchange Agent Agreement”).

At or prior to the Closing, Company will issue and cause to be deposited with the Exchange Agent, for the benefit of Sellers, for exchange

in accordance with this Article 1, through the Exchange Agent, uncertificated book-entries representing such aggregate number

of shares of Company Common Stock to be issued pursuant to Section 1.4, and, after the Closing, the Exchange Agent shall be authorized

to issue the shares of Company Common Stock in accordance with this Agreement.

(b) Exchange Procedures.

On or prior to the Closing, each Seller, as a condition to receiving the applicable Acquisition Consideration, will deliver to the Exchange

Agent an original of a duly executed (in wet-ink) written share assignment declaration in favor of Company in customary form approved

by Company in respect of the Santersus Shares held by such Seller (each, a “Share Assignment Declaration”).

As promptly as practicable after receipt by the Exchange Agent from a Seller of the Share Assignment Declaration, together with such

other customary documents as may reasonably be required by the Exchange Agent or Company, such Seller shall receive, from the Exchange

Agent, in exchange therefor, a number of whole shares of Company Common Stock represented, at such Seller’s election, by book entry

or certificated shares equal to the number of whole shares of Company Common Stock that such Seller has the right to receive pursuant

to the provisions of Section 1.4.

written consent, any shares of Company Common Stock are to be issued in a name other than that in which the Santersus Shares surrendered

in exchange therefor is registered as of the date hereof, it will be a condition of the issuance thereof that the Person requesting such

exchange evidence the valid transfer of the relevant Santersus Shares to the Person he/she/it designates, and that the Person requesting

such exchange will have paid to Company or any Person designated by it any transfer or other Taxes required by reason of the issuance

of the shares of Company Common Stock in any name other than that of the registered holder of the Santersus Share surrendered, or established

to the satisfaction of Company or any agent designated by it that such Tax has been paid or is not payable.

(d)

Withholding Rights. Each of the Exchange Agent, Company and Santersus will be entitled to deduct and withhold from any consideration

payable or otherwise deliverable pursuant to this Agreement any amounts that are required to be deducted or withheld from that consideration

under the Code, Treasury Regulations promulgated under the Code or any provisions of applicable state, local or foreign Tax law; provided,

however, that if Company determines that any such deduction or withholding is required, other than any deduction or withholding

relating to amounts treated as compensation for Tax purposes, Company shall use commercially reasonable efforts to provide notice to the

Seller Representative of its intent to deduct or withhold as soon as reasonably practicable prior to the payment to which such deduction

or withholding would apply, and shall reasonably cooperate with the Seller Representative to mitigate or eliminate any such deduction

or withholding to the extent permitted by applicable Legal Requirements. To the extent any amounts are withheld in accordance with the

provisions of this Agreement and are paid over to the applicable Governmental Body, such amounts will be treated for all purposes under

this Agreement as having been paid to the Person to whom such amounts would otherwise have been paid.

1.8

No Further Rights. The Acquisition Consideration delivered upon the surrender for exchange of Santersus Shares in accordance

with the terms of this Agreement will be deemed to have been issued in full satisfaction of all rights pertaining to such shares.

1.9

Additional Actions. If, at any time after the Closing, Company shall consider or be advised that any deeds, bills of

sale, assignments or assurances or any other acts or things are necessary, desirable or proper (a) to vest, perfect or confirm, of record

or otherwise, in it its right, title and interest in, to or under any of the rights, privileges, powers or franchises of the Santersus

Shares or (b) otherwise to carry out the purposes of this Agreement, Company and its proper officers and directors or their designees

shall be authorized (i) to execute and deliver, in the name and on behalf of each Seller and Santersus, all such deeds, bills of sale,

assignments and assurances and (ii) to do, in the name and on behalf of each Seller and Santersus, all such other acts and things as may

be necessary, desirable or proper to vest, perfect or confirm Company’s right, title and interest in, to and under any of the rights,

privileges, powers or franchises of Santersus Shares and otherwise to carry out the purposes of this Agreement; provided that,

prior to executing and delivering any deed, bill of sale, assignment or assurance or doing any other act or thing in the name of and on

behalf of any Seller pursuant to this Section 1.9, Company shall use commercially reasonable efforts to contact such Seller and

request that such Seller execute and deliver such deed, bill of sale, assignment or assurance or do such other act or thing.

Article

REPRESENTATIONS AND WARRANTIES OF SANTERSUS

Santersus represents and warrants

to Company as follows (it being understood that each representation and warranty contained in this Article 2 is subject to: (a)

the exceptions and disclosures set forth in the part or subpart of the Santersus Disclosure Schedule corresponding to the particular Section

or subsection in this Article 2 in which such representation and warranty appears; (b) any exceptions or disclosures explicitly

cross-referenced in such part or subpart of the Santersus Disclosure Schedule by reference to another part or subpart of the Santersus

Disclosure Schedule; and (c) any exception or disclosure set forth in any other part or subpart of the Santersus Disclosure Schedule to

the extent it is reasonably apparent on the face of such exception or disclosure that such exception or disclosure qualifies such representation

and warranty):

2.1

Organization and Qualification; Charter Documents

(a) Part 2.1(a) of the

Santersus Disclosure Schedule identifies each Subsidiary of Santersus and indicates its jurisdiction of organization. None of the Santersus

Companies own any capital stock of, or any equity interest of any nature in, any other Entity, other than the Entities identified on

Part 2.1(a) of the Santersus Disclosure Schedule. The Santersus Companies have not agreed nor are any obligated to make, nor are

any bound by any Contract under which such Santersus Company may become obligated to make, any future equity investment in or capital

contribution to any other Entity.

(b) Each of the Santersus Companies is a corporation duly organized, validly existing, has a correct

commercial-register entry and does not have any liquidation or insolvency proceedings pending and has all necessary corporate power and

authority: (i) to conduct its businesses in the manner in which its business is currently being conducted and presently proposed to be

conducted; (ii) to own and use its assets in the manner in which its assets are currently owned and used; and (iii) to perform its obligations

under all Santersus Contracts by which it is bound, except where the failure to have such corporate power and authority would not, individually

or in the aggregate, have a Santersus Material Adverse Effect. The Organizational Documents of each Santersus Company, copies of which

have previously been made available to Company, are true, correct and complete copies of such documents as currently in effect and no

Santersus Company is in violation of any provision thereof in any material respect. The copy of the minute books of the Santersus Companies

made available to Company contains minutes of all meetings of directors and stockholders and all actions by written consent without a

meeting by the directors and stockholders since January 1, 2023 of each Santersus Company and accurately reflects in all material respects

all actions by the directors (and any committee of directors) and stockholders of each Santersus Company.

2.2 Capital Structure.

(a)

As of the date hereof, the issued share capital of Santersus consists of (i) 2,164,490 ordinary shares of Santersus, par value

CHF 0.10 per share (“Santersus Ordinary Shares”) and (ii) 455,679 Series Preferred A Shares of Santersus, par

value CHF 0.10 per share (“Santersus Preferred Shares,” and, together with the Santersus Ordinary Shares, the

“Santersus Issued Share Capital”). All Santersus Issued Share Capital is, and immediately prior to Closing,

all Santersus Shares will be, duly authorized, validly issued, fully paid and nonassessable and was, or will be, issued in compliance

with all applicable Legal Requirements. None of the Santersus Companies hold any capital stock in their respective treasuries. The Santersus

Issued Share Capital exists as uncertificated securities, and no share certificate(s) representing the Santersus Shares have been issued

after their conversion from bearer shares (Inhaberaktien) to registered shares (Namenaktien) in 2019. Such bearer shares

were duly cancelled and destroyed in 2019. As of the date hereof, there are no equity securities of Santersus outstanding other than the

Santersus Issued Share Capital.

(b)

Part 2.2(b) of the Santersus Disclosure Schedule sets forth the complete and accurate capitalization of the Santersus Companies

as of the date hereof (including the name of each holder of Santersus Issued Share Capital and the number of shares in the Santersus Issued

Share Capital held by such holder). Other than the Santersus Share Conversion, no Person would have the right to cause Santersus to issue

any shares in the Santersus Share Capital except for the issuance of Santersus Ordinary Shares upon the exercise of certain Santersus

Options (and the payment of the applicable exercise price) that Company or Santersus, on behalf of Company, have the right and obligation

to procure the compulsory purchase of pursuant to Section 6.15. As of the Closing, Part 2.2(b) of the Santersus Disclosure

Schedule will set forth the complete and accurate capitalization of the Santersus Companies after giving effect to the issuance of Santersus

Ordinary Shares pursuant to the exercise of Santersus Options (and the payment of the applicable exercise price) outstanding on the Closing

Date in accordance with the terms under the Santersus Option Plan. As of the Closing, all of the Santersus Share Capital listed on

such updated Part 2.2(b) of the Santersus Disclosure Schedule will constitute Santersus Shares hereunder and no other shares in

the Santersus Share Capital would be issued or issuable upon the exercise or conversion of any securities of Santersus or upon the exchange

of any such securities and no Person would have the right to cause Santersus to issue any shares in the Santersus Share Capital except

for the issuance of Santersus Ordinary Shares upon the exercise of certain Santersus Options (and the payment of the applicable exercise

price) that Company or Santersus, on behalf of Company, have the right and obligation to procure the compulsory purchase of pursuant to

Section 6.15.

(c)

As of the date hereof, Santersus has reserved an aggregate of 600,000 Santersus Ordinary Shares for issuance under the Santersus

Option Plan for the Santersus Options. All Santersus Ordinary Shares subject to issuance pursuant to a Santersus Option would be duly

authorized, validly issued, fully paid and nonassessable and would be issued in compliance with all applicable Legal Requirements. Part

2.2(c) of the Santersus Disclosure Schedule lists each outstanding Santersus Option outstanding as of the date hereof, the name of

the holder of such option, the number of shares subject to such option, the exercise price of such option, the vesting schedule and termination

date of such option, and whether the exercisability of such option or vesting of such option will be accelerated in any way by the Contemplated

Transactions. Except as set forth on Part 2.2(c) of the Santersus Disclosure Schedule, each Santersus Option was granted with an

exercise price not less than the fair market value of a Santersus Ordinary Share on the date such option was approved by the board of

directors of Santersus or an authorized committee or representative thereof. The Santersus Option Plan is valid and enforceable as per

its terms.

(d)

Except as set forth on Part 2.2(d) of the Santersus Disclosure Schedule: (i) none of the shares of Santersus Share Capital

or shares in the capital of any of Santersus’ Subsidiaries are entitled or subject to any preemptive right, right of repurchase

or forfeiture, right of participation, right of maintenance or any similar right; (ii) none of the shares of Santersus Share Capital or

shares in the capital of any of Santersus’ Subsidiaries are subject to any right of first refusal; (iii) there are no outstanding

bonds, debentures, notes or other indebtedness of the Santersus Companies having a right to vote on any matters on which the holders of

shares of Santersus Share Capital or holders of shares in the capital of any of Santersus’ Subsidiaries have a right to vote; (iv)

except for the Santersus Shareholders Agreement, there is no Contract to which a Santersus Company is a party relating to the voting or

registration of, or restricting any Person from purchasing, selling, pledging or otherwise disposing of (or from granting any option or

similar right with respect to), any shares of Santersus Share Capital or shares in the capital of any of Santersus’ Subsidiaries;

and (v) no Santersus Company is under any obligation, or is bound by any Contract pursuant to which it may become obligated, to repurchase,

redeem or otherwise acquire any shares of Santersus Share Capital or shares in the capital of any of Santersus’ Subsidiaries or

other securities. Except as set forth on Part 2.2(d) of the Santersus Disclosure Schedule, as of the date hereof, there are no

shares of Santersus Share Capital that are subject to a repurchase option, risk of forfeiture or other condition under any Contract with

Santersus or under which Santersus or, to the knowledge of Santersus, any Seller has any rights.

(e)

Upon Closing and assuming the satisfaction or waiver of the conditions to Closing set forth in Article 7, Company will acquire

all Santersus Shares free and clear of any Encumbrance (except as are imposed by federal and state securities laws), and pursuant to the

provisions of Section 6.15, the Company or Santersus on the Company’s behalf, will have the right to acquire all shares in

the Santersus Share Capital issuable after Closing upon the exercise of any Santersus Option which is not exchanged pursuant to the provisions

of Section 6.15 free and clear of any Encumbrance (except as are imposed by federal and state securities laws).

2.3

Authority; Non-Contravention; Approvals.

(a) Santersus has the requisite

corporate power and authority to enter into this Agreement and to perform its obligations hereunder and to consummate the Contemplated

Transactions. The execution and delivery by Santersus of this Agreement, the performance by Santersus of its obligations hereunder and

the consummation by Santersus of the Contemplated Transactions have been duly authorized by all necessary corporate action on the part

of Santersus, and Santersus has made available to the Company a copy of such resolutions prior to the execution of this Agreement. This

Agreement has been duly executed and delivered by Santersus and, assuming the due authorization, execution and delivery of this Agreement

by Company and Sellers, this Agreement constitutes the valid and binding obligation of Santersus, enforceable in accordance with its

terms, subject to applicable bankruptcy, insolvency, fraudulent transfer, reorganization, moratorium and other laws affecting creditors’

rights generally and general principles of equity.

(b) Except as set forth on Part 2.3(b) of the Santersus Disclosure Schedule,

the execution and delivery of this Agreement by Santersus does not, and the performance of this Agreement by Santersus will not, (i)

conflict with or violate any Organizational Documents of any Santersus Company, (ii) subject to compliance with the requirements set

forth in Section 2.3(c) below, conflict with or violate any Legal Requirement or Order applicable to the Santersus Companies or

by which any of their respective properties are bound or affected, except for any such conflicts or violations that would not, individually

or in the aggregate, have a Santersus Material Adverse Effect or (iii) require a Santersus Company to make any filing with or give any

notice to a Person, or to obtain any Consent from a Person, or result in any breach of or constitute a default (or an event that with

notice or lapse of time or both would become a default) under, or impair Santersus’ rights or alter the rights or obligations of

any third party under, or give to others any rights of termination, amendment, acceleration or cancellation of, or result in the creation

of a lien or encumbrance on any of the properties or assets of the Santersus Companies, except, for purposes of this clause (iii), as

would not, individually or in the aggregate, have a Santersus Material Adverse Effect.

(c)

No consent, approval, order or authorization of, or registration, declaration or filing with, any Governmental Body is required

by or with respect to Santersus in connection with the execution and delivery of this Agreement or the consummation of the Contemplated

Transactions, except for (i) the filing of the Proxy Statement and Registration Statement with the SEC, (ii) any filings contemplated

by Section 6.4(a) or (iii) those consents obtained from Sellers by their execution and delivery of this Agreement by Sellers.

2.4

Santersus Financial Statements; No Undisclosed Liabilities.

(a) The audited consolidated

financial statements (including any related notes thereto), consisting of results of operations and statements of changes in cash flow

of Santersus and its Subsidiaries as of and for the years ended December 31, 2024 and December 31, 2025 (collectively, the “Santersus

Audited Financials”), have been delivered to Company and (i) have been prepared in accordance with generally accepted accounting

principles in the United States (“GAAP”) applied on a consistent basis throughout the periods involved (except

as may be indicated in the notes thereto), (ii) fairly present, in all material respects, the consolidated financial position of the

Santersus Companies as at the respective dates thereof and the consolidated results of their operations and cash flows for the periods

indicated and (iii) be consistent with, and have been prepared from, the books and records of the Santersus Companies. The Santersus

Audited Financials, when delivered by Santersus for inclusion in the Proxy Statement and Registration Statement for filing with the SEC

following the date of this Agreement, will comply as to form in all material respects with the published rules and regulations of the

SEC applicable thereto, in effect as of the dates thereof.

(b) The unaudited consolidated

financial statements (including any related notes thereto) representing the financial condition of Santersus Companies as of and for

the sixth (6)-month period ended June 30, 2026, and Santersus financial statements as of and for the period ending on any fiscal quarter

end or annual period after the date hereof and prior to the Closing that are required to be included in the Proxy Statement and Registration

Statement, if any, in each case together with the notes thereto (the “Santersus Unaudited Financials,” and

together with the Santersus Audited Financials, the “Santersus Financials”), will, when delivered to Company,

(i) for inclusion in the Proxy Statement and Registration Statement for filing with the SEC following the date of this Agreement, comply

as to form in all material respects with the published rules and regulations of the SEC applicable thereto, in effect as of the dates

thereof, (ii) have been prepared in good faith, (iii) fairly present, in all material respects, the consolidated financial position of

the Santersus Companies as at the respective dates thereof and the consolidated results of the Santersus Companies operations and cash

flows for the periods indicated and (iv) be consistent with (subject to normal and recurring year-end adjustments that are not reasonably

expected to be material in amount), and have been prepared from, the books and records of the Santersus Companies.

of internal accounting controls appropriate for a company of its size and stage of development, which are designed to provide reasonable

assurance that: (i) transactions are executed in accordance with management’s general or specific authorizations; (ii) transactions

are recorded as necessary to permit preparation of financial statements in conformity with GAAP and to maintain asset accountability;

(iii) access to assets is permitted only in accordance with management’s general or specific authorization; and (iv) the recorded

accountability for assets is compared with the existing assets at reasonable intervals and appropriate action is taken with respect to

any differences. Santersus maintains internal controls over financial reporting that provides reasonable assurance regarding the reliability

of financial reporting and the preparation of financial statements for external purposes in accordance with GAAP.

(d) As of the date of this

Agreement, no Santersus Company has any liabilities (other than valuation adjustments in relation to financial instruments), indebtedness,

obligations or expense of any kind, whether absolute, accrued, contingent, matured or unmatured or otherwise (each, a “Liability”),

of a type required to be reflected in financial statements prepared in accordance with GAAP, which are, individually or in the aggregate,

material to the business, results of operations or financial condition of the Santersus Companies taken as a whole, except for (i) Liabilities

reflected on the Santersus Audited Financials, (ii) Liabilities incurred by any Santersus Company since the date of the Santersus Audited

Financials in the ordinary course of business and which are not in excess of CHF 250,000, in the aggregate, (iii) Liabilities incurred

in connection with the Contemplated Transactions, (iv) Liabilities for performance of obligations of Santersus or any Subsidiary under

any Santersus Contract (other than for breach thereof) and (v) Liabilities disclosed on Part 2.4(d) of the Santersus Disclosure

Schedule. No Santersus Company has any “off-balance sheet arrangements” (as defined in Item 303(a) of SEC Regulation S-K).

(e) Since January 1, 2024,

there have been no formal investigations regarding financial reporting or accounting policies and practices discussed with, reviewed

by or initiated at the direction of the chief executive officer, chief financial officer or general counsel of Santersus, the board of

directors of Santersus or any committee thereof.

(f) Since January 1, 2024, neither Santersus nor, to the Knowledge of Santersus, its

independent auditors have identified (i) any significant deficiency or material weakness in the system of internal accounting controls

utilized by Santersus, (ii) any fraud, whether or not material, that involves Santersus’ management or other employees who have

a role in the preparation of financial statements or the internal accounting controls utilized by Santersus or (iii) any claim or allegation

regarding any of the foregoing. No Santersus Company has identified or been made aware of any fraud, whether or not material, that involved

Santersus’ management or other employees who have a role in the preparation of financial statements or the internal accounting

controls utilized by Santersus, any material illegal act or fraud related to the business of the Santersus Companies, or any claim or

allegation regarding the foregoing.

2.5 Absence of Certain

Changes or Events. Except as set forth on Part 2.5 of the Santersus Disclosure Schedules, since December 31, 2025 through

the date hereof, each of the Santersus Companies has conducted its business in all material respects in the ordinary course of business

consistent with past practice and there has not been (a) any event that has had a Santersus Material Adverse Effect or (b) any action,

event or occurrence that would have required the consent of Company pursuant to Section 5.2 had such action, event or occurrence

taken place after the execution and delivery of this Agreement.

2.6 Taxes. Each of the representations and warranties set

forth in this Section 2.6 is qualified by “except as would not, individually or in the aggregate, have a Santersus Material

Adverse Effect”

(a) Each income Tax Return

and each other material Tax Return that were required to be filed by or with respect to any Santersus Company has been timely filed (taking

into account all valid extensions), and all such Tax Returns were true, complete and accurate in all respects. All Taxes due and payable

by the Santersus Companies (whether or not shown on any Tax Return) have been timely paid, except to the extent such amounts are being

contested in good faith and are properly reserved for on the books or records of the Santersus Companies to the extent any such reserve

is required under GAAP.

(b) No waiver or agreement

by or with respect to a Santersus Company is in force for the extension of time for the payment, collection or assessment of any Taxes,

and no request has been made by a Santersus Company in writing for any such extension or waiver.

Taxes on any asset of a Santersus Company other than liens for Taxes not yet due and payable or Taxes contested in good faith and reserved

against in accordance with GAAP.

(d) No Santersus Company is

the subject of any currently ongoing Tax audit or other proceeding with respect to Taxes nor has any audit or other proceeding with respect

to Taxes been proposed against any of them in writing, and any deficiencies asserted or assessments made as a result of any audit or

other proceeding with respect to Taxes have been paid in full or adequate accruals or reserves for any such deficiencies or assessments

have been established and will be reflected in the Santersus Financials.

(e) All material Taxes that

a Santersus Company has been required to collect or withhold have been duly collected or withheld and, to the extent required by applicable

Legal Requirements when due, have been duly and timely paid to the proper Governmental Body.

(f) No closing agreements, private letter

rulings, technical advice memoranda or similar agreements or rulings have been entered into by any Santersus Company with any taxing

authority or issued by any taxing authority to a Santersus Company. There are no outstanding rulings of, or request for rulings with,

any Governmental Body addressed to a Santersus Company that are, or if issued would be, binding on any Santersus Company.

(g) No Santersus Company is

a party to any Contract with any Person (other than one or more Santersus Companies) relating to allocating or sharing the payment of,

or Liability for, Taxes or Tax benefits (other than pursuant to customary provisions included in agreements not primarily related to

Taxes and entered into in the ordinary course of business). No Santersus Company has any Liability for the Taxes of any Person (other

than one or more Santersus Companies) as a transferee or successor or otherwise by operation of Legal Requirements.

(h) Within the past

two (2) years, no Santersus Company has been a member of an affiliated group of corporations within the meaning of Section 1504 of the

Code or of any group that has filed a combined, consolidated or unitary Tax Return under applicable state, local or foreign Tax Legal

Requirement (other than a group the common parent of which was Santersus).

(i) No Santersus Company has

participated in, or is currently participating in, a “listed transaction” within the meaning of Treasury Regulation Section

1.6011-4(b)(2).

(j) Within the past two (2)

years, no Santersus Company has distributed stock of another Person, or has had its stock distributed by another Person, in a transaction

that was purported or intended to be governed in whole or in part by Sections 355 or 361 of the Code.

(k) No Santersus Company has

been a United States real property holding corporation within the meaning of Section 897(c)(2) of the Code during the applicable period

specified in Section 897(c)(1)(A)(ii).

(l) No Santersus Company is,

or ever has been, a “controlled foreign corporation,” as such term is defined in Section 957 of the Code.

(m) No Santersus

Company is aware of the existence of any fact, or has taken or agreed to take any action, that could reasonably be expected to prevent

the Acquisition from qualifying as a “reorganization” within the meaning of Section 368(a) of the Code.

2.7 Intellectual Property.

(a)

All Santersus IP Rights are:

(i) legally and beneficially

owned by the Santersus Companies or lawfully used in accordance with a license agreement (which is in full force and effect without default

or breach by any party thereto);

(ii) valid and, to Santersus’

knowledge, not being infringed or challenged or opposed by any Person and no claims with regard to these rights have been made; and

(iii)

not subject to any Encumbrance or any license in favor of another Person.

The Santersus Companies have

fully paid all registration fees for the Santersus IP Rights and none of the Santersus IP Rights are subject to (existing or proposed)

Encumbrance. Each Santersus Company has taken precautions and measures to protect and maintain the confidentiality of their respective

trade secrets and know-how.

(b) To the knowledge of Santersus, the Santersus Companies own, possess, have developed, or have acquired

on commercially reasonable terms, legal rights to the Santersus IP Rights sufficient to carry out their respective business as now conducted.

or service or activity of any Santersus Company has infringed or violated or infringes or otherwise violates any IP Rights of a third

Person; provided that the foregoing representation is made to Santersus’ knowledge.

(d) To the knowledge of Santersus,

by conducting any Santersus Company’s business as currently conducted or as presently proposed, the Santersus Companies would not

infringe or violate any of the IP Rights of a third Person. No Santersus Company has received any unsolicited offers to license any IP

Rights from any Person.

(e) To the knowledge of Santersus, no Person is presently infringing any Santersus IP Rights in a way that is

expected to have a Santersus Material Adverse Effect.

(f)

Other than pursuant to: (i) standard end-user license or services agreements for the Santersus Companies’ products and services

on substantially the Santersus Companies’ standard forms made available to Company; (ii) customary nondisclosure agreements entered

into by any Santersus Company in the ordinary course of business (that do not include any terms (w) granting the right to use residuals,

(x) assigning IP Rights, (y) granting express license rights or (z) constituting a covenant not to assert IP Rights); (iii) nonexclusive

feedback licenses and nonexclusive licenses to use trademarks, in each case that are incidental to the subject matter of the applicable

agreement in which they are incorporated; and (iv) licenses to a service provider solely for the purpose of allowing such service provider

to provide services to any Santersus Company (collectively, “Standard Outbound Agreements”), the Santersus Companies

have not granted to any Person any options, licenses, covenants not to assert, agreements, claims, encumbrances or shared ownership interests

of any kind relating to the Santersus IP Rights that are material to the Santersus Companies’ business as now conducted.

(g)

Other than pursuant to: (i) standard license or services agreements for commercially available software products and cloud services

non-exclusively licensed to a Santersus Company under standard terms; (ii) backup licenses from employees and contractors granted in connection

with providing services to a Santersus Company; (iii) licenses to Open Source Software; (iv) customary nondisclosure agreements entered

into by any Santersus Company in the ordinary course of business that do not include any terms (w) granting the right to use residuals,

(x) assigning IP Rights, (y) granting express license rights or (z) constituting a covenant not to assert IP Rights; (v) nonexclusive

feedback licenses and nonexclusive licenses to use trademarks, in each case that are incidental to the subject matter of the applicable

agreement in which they are incorporated; and (vi) licenses to a Santersus Company solely for the purpose of enabling such Santersus Company

to provide services to the licensor (collectively, “Standard Inbound Agreements”), no Santersus Company is bound

by or a party to any options, licenses, covenants not to assert or other grants or agreements of any kind with respect to IP Rights of

any Person that are material to the Santersus Companies’ business as now conducted.

(h)

Each Santersus Company has taken commercially reasonable measures to maintain and protect all confidential information and trade

secrets of such Santersus Company that such Santersus Company intended to maintain as a confidential or a trade secret. To Santersus’

knowledge, there has been no unlawful, accidental or unauthorized access to or use or disclosure of any confidential information and trade

secrets of any Santersus Company that such Santersus Company intended to maintain as confidential or a trade secret.

(i)

(i) Each current and former employee of a Santersus Company has assigned to such Santersus Company all IP Rights that such employee

has solely or jointly conceived, reduced to practice, developed, or made during the period of employment with such Santersus Company that:

(A) relate, at the time of conception, reduction to practice, development, or making of such IP Right, to such Santersus Company’s

business as then conducted or as then proposed to be conducted; (B) were developed on any amount of such Santersus Company’s time

or with the use of any of such Santersus Company’s equipment, supplies, facilities or information; or (C) resulted from such individual’s

performance of services for such Santersus Company; (ii) each current and former consultant of any Santersus Company who was involved

in the development of any material IP Rights for a Santersus Company or that are otherwise owned or purported to be owned by a Santersus

Company has assigned to such Santersus Company all IP Rights that such consultant has solely or jointly conceived, reduced to practice,

developed, or made during the period of its consulting relationship with such Santersus Company that resulted from such consultant’s

performance of services for such Santersus Company; (iii) each such employee and consultant has executed an agreement with the applicable

Santersus Company regarding confidentiality and proprietary information, and assignment of IP Rights developed by or for such Santersus

Company, in the form(s) made available to Company (the “Confidential Information Agreements”); (iv) no such

employee or consultant has excluded IP Rights from the assignment of IP Rights pursuant to such Person’s Confidential Information

Agreement, which excluded IP Rights would be material to a Santersus Company in the conduct of such Santersus Company’s business

as now conducted or currently proposed to be conducted; and (v) no Santersus Company is aware that any current or former employee or consultant

is in violation of any Confidential Information Agreement.

(j)

Part 2.7(j)(i) of the Santersus Disclosure Schedule lists all of the Patent Rights, Trademark Rights (including domain name

registrations) and registered Copyrights owned solely by or registered solely to any Santersus Company as of the date hereof, setting

forth in each case, as applicable, the jurisdictions in which patents have been issued, patent applications have been filed, trademarks

have been registered and trademark applications have been filed, along with the respective application, registration or filing number

thereof. Part 2.7(j)(ii) of the Santersus Disclosure Schedule lists, as of the date hereof, all of the Patent Rights, Trademark

Rights (including domain name registrations) and registered Copyrights in which any Santersus Company has any co-ownership interest, other

than those owned solely by a Santersus Company, setting forth in each case, as applicable, the jurisdictions in which patents have been

issued, patent applications have been filed, trademarks have been registered, trademark applications have been filed and registered copyrights

and copyright applications have been filed, along with the respective application, registration or filing number thereof. Part 2.7(j)(iii)

of the Santersus Disclosure Schedule lists all of the third party Patent Rights, Trademark Rights (including domain name registrations)

and registered Copyrights in which a Santersus Company has any exclusive right, title or interest, other than those owned solely or co-owned

by a Santersus Company and identified on Part 2.7(j)(i) or Part 2.7(j)(ii) of the Santersus Disclosure Schedule.

(k)

No Santersus Company has embedded, used, linked or distributed any open source, software, technologies or other materials that

are licensed or distributed under any license arrangement or other distribution model qualifying for the “Open Source” definition

promulgated by the Open Source Initiative at www.opensource.org/osd or any other public domain or “community” (or similar)

materials (collectively “Open Source Software”) in connection with any of its products or services or proprietary

materials in any manner that requires, or purports to require: (i) any material software code owned or authored by or on behalf of a Santersus

Company (“Santersus Code”) to be disclosed or distributed in source code form or be licensed for the purpose

of making derivative works; (ii) any restriction on the consideration to be charged for the distribution of any such Santersus Code; (iii)

the grant to any third Person of any rights or immunities under material Santersus IP Rights; or (iv) any other material limitation, restriction

or condition on the right of any Santersus Company with respect to its use or distribution of any material Santersus IP Rights (other

than attribution, warranty and liability disclaimer, and notice delivery conditions). Each Santersus Company is in material compliance

with all licenses for Open Source Software that it embeds, links to, uses or distributes.

(l)

Except as set forth on Part 2.7(l) of the Santersus Disclosure Schedule, no government funding, facilities of a university,

college, hospital, foundation, other educational institution or research center, or other funding from third Persons provided specifically

for research and development was used in the development of any Santersus IP Rights in a manner that has resulted in such entity retaining

any claim of ownership or right to use any such Santersus IP Rights. To Santersus’ knowledge, no Person who was involved in, or

who contributed to, the creation or development of any Santersus IP Rights, has performed services for the government, university, college,

hospital, foundation, or other educational institution or research center in a manner that would affect any Santersus Company’s

rights in the Santersus IP Rights.

(m)

As at the date of this Agreement, the agreement dated January 28, 2022, entered into between Santersus and Belgian Volition Srl,

has been terminated and Volition has no, and will not have any, right to exercise its buy-out option to acquire irrevocable rights in

the field of whole blood apheresis and related Santersus IP Rights as a result of the Acquisition.

2.8

Data Privacy.

(a)

Except as set forth on Part 2.8(a) of the Santersus Disclosure Schedules, in connection with the collection, storage, use,

access, disclosure and/or other processing Personal Data, by or on behalf of any Santersus Company, to Santersus’ knowledge, each

Santersus Company is and has been in compliance in all material respects with the following: (i) all applicable Legal Requirements governing

privacy or data security in all relevant jurisdictions relating to data loss, data theft, and security breach notification obligations,

telephone or text message communications, artificial intelligence and automated decision-making, or marketing by email or other channels;

(ii) such Santersus Company’s published privacy policies; and (iii) the privacy or data security requirements of any contracts,

codes of conduct, or industry standards by which such Santersus Company is legally bound.

(b)

Except as set forth on Part 2.8(b) of the Santersus Disclosure Schedules, each Santersus Company maintains and has maintained

reasonable physical, technical, and administrative security measures and policies designed to protect all Personal Data and confidential

or proprietary data owned, stored, used, maintained or controlled by or on behalf of such Santersus Company from and against unlawful,

accidental or unauthorized access, destruction, loss, use, modification, disclosure, and/or other processing.

(c)

There has been no material security breach, unauthorized access, use, disclosure, modification, destruction or other incident or

compromise of or relating to any of the Santersus Companies’ information technology and computer systems, networks, hardware, software,

data (including all Personal Data and the data of their respective customers, employees, suppliers, vendors and any third party data maintained

by or on behalf of them), equipment or technology (collectively, “Santersus IT Systems and Data”) and, to Santersus’

knowledge, no event or condition exists as of the date of this Agreement that would reasonably be expected to result in, any such material

security breach, unauthorized access, use, disclosure, modification, destruction or other compromise of Santersus IT Systems and Data.

The Santersus Companies employ commercially reasonable physical, technical, and administrative security measures, controls, safeguards,

policies and procedures designed to (i) protect all Santersus IT Systems and Data from and against material unauthorized access, use and/or

disclosure and (ii) maintain the integrity, continuous operation, redundancy and security of the Santersus IT Systems and Data. The Santersus

Companies are presently, and since January 1, 2023 have been, in compliance in all material respects with all applicable Legal Requirements

governing the data privacy and security of Personal Data, and all judgments, orders, rules, directives and decrees of any court or arbitrator

or governmental or regulatory authority, company policies and contractual obligations relating to the privacy and security of Santersus

IT Systems and Data and to the protection of such Santersus IT Systems and Data from unauthorized use, access, misappropriation or modification,

except as would not, individually or in the aggregate, have a Santersus Material Adverse Effect, and the Santersus Companies have implemented

backup and disaster recovery technology consistent with industry standards and practices.

(d)

No Person (including any Governmental Body) has asserted a claim, or otherwise threatened in writing to commence any action, against

any Santersus Company alleging a violation of any privacy policy of the Santersus Companies or any applicable Legal Requirements pertaining

to privacy and data protection. No Santersus Company has received any written inquiry or complaint from any Governmental Body regarding

the collection, use, retention, storage, security, transfer, disposal, disclosure or other processing of Personal Data or confidential

or proprietary data by or for the Santersus Companies.

2.9

Compliance with Legal Requirements.

(a)

Except as set forth on Part 2.9(a) of the Santersus Disclosure Schedules, since January 1, 2023, each Santersus Company

has conducted and, as of the date hereof continues to conduct, its business in compliance in all material respects with all applicable

Legal Requirements and Orders.

(b)

Since January 1, 2023, no investigation or inquiry is pending or threatened in writing and no Order has been issued by any Governmental

Body or self-regulatory body regarding any matter against any Santersus Company or, to the knowledge of Santersus, any Person for whose

acts or omissions a Santersus Company may be liable in connection with the breach or alleged breach of any Legal Requirements. No Santersus

Company is under any obligation to remedy any unlawful situation in respect of any of its assets or activities.

(c)

No Santersus Company is in violation or default (i) of any provisions of its Organizational Documents, (ii) of any Order, (iii)

under any note, indenture or mortgage, (iv) under any Contract to which it is a party or by which it is bound that is required to be listed

on the Santersus Disclosure Schedule or (v) of any provision of any federal or state statute, rule or regulation applicable to any Santersus

Company, in each case of clause (ii) through (v), the violation of which would have a Santersus Material Adverse Effect.

(d)

Except as set forth on Part 2.9(d) of the Santersus Disclosure Schedules, each Santersus Company has all franchises, permits,

registrations, certifications, authorizations, clearances, approvals, licenses and any similar authority necessary for the conduct of

its business (the “Santersus Permits”), the lack of which would reasonably be expected to have a Santersus Material

Adverse Effect. No Santersus Company is in default in any material respect under any of such Santersus Permits. No Order is pending or,

to the knowledge of Santersus, threatened in writing, which seeks to revoke or limit any Santersus Permit. Santersus has made available

to Company all Santersus Permits.

(e)

(i) During the past five (5) years the Santersus Companies and their Subsidiaries have complied with applicable Legal Requirements

pertaining to trade and economic sanctions administered by the United States, European Union, United Kingdom or Switzerland (collectively,

“Sanctions”); (ii) none of the Santersus Companies, their Subsidiaries, or their respective directors or officers,

or, to Santersus’ knowledge, employees or any Santersus Company’s or its Subsidiaries’ agents is: (A) organized under

the laws of, ordinarily resident in, or located in a country or territory that is the subject of comprehensive Sanctions (which as of

the date of this Agreement comprise Cuba, Iran, North Korea, Syria, and the Crimea, Donetsk, and Luhansk regions of Ukraine (“Restricted

Countries”)); (B) 50% or more owned or controlled by the government of a Restricted Country; or (C)(1) designated on a sanctioned

parties list administered by the United States, European Union, United Kingdom or Switzerland, including, without limitation, the U.S.

Department of the Treasury’s Office of Foreign Assets Control’s Specially Designated Nationals and Blocked Persons List, Foreign

Sanctions Evaders List, Sectoral Sanctions Identification List, the Consolidated List of Persons, Groups, and Entities Subject to EU Financial

Sanctions, and the UK’s Consolidated Sanctions List (collectively, “Designated Parties”) or (2) 50% or

more owned or, where relevant under applicable Sanctions, controlled, individually or in the aggregate, by one or more Designated Party,

in each case only to the extent that dealings with such persons are prohibited pursuant to applicable Sanctions; (iii) during the past

five (5) years, none of the Santersus Companies, their Subsidiaries, or their respective directors or officers, or, to Santersus’

knowledge, their respective employees, (x) has been the subject or target of any investigation, prosecution, other enforcement action,

or government inquiry related to Sanctions violations or (y) submitted a voluntary self-disclosure to any U.S. or, other relevant government

agency regarding actual or potential Sanctions violations; and (iv) each Santersus Company maintains policies and procedures reasonably

designed to promote compliance with applicable Sanctions.

(f)

None of the Santersus Companies and, to the knowledge of Santersus, no Representative or employee of any Santersus Company or Person

acting in concert with or on behalf of the Santersus Companies, or any officers of the same with respect to any matter relating to any

of the Santersus Companies, has: (i) used any funds for unlawful contributions, gifts, entertainment or other unlawful expenses relating

to political activity; (ii) made any unlawful payment to foreign or domestic government officials or employees or to foreign or domestic

political parties or campaigns or violated any provision of the U.S. Foreign Corrupt Practices Act of 1977, the U.K. Bribery Act of 2010

or any other analogous legislation in any jurisdiction, as amended (collectively, the “Anti-Corruption Laws”);

or (iii) made any other unlawful payment.

(g)

Since January 1, 2023, each Santersus Company has been in material compliance with all applicable Legal Requirements administered

or enforced by the FDA or any similar Governmental Body regarding developing, testing, manufacturing, marketing, distributing or promoting

the products of such Santersus Company, including complaint handling or adverse event reporting.

(h)

At no time since January 1, 2023 has any of the Santersus Companies received written notice that any Governmental Body or institutional

review board has commenced, or threatened to initiate, any proceeding seeking the suspension or termination of nonclinical or clinical

research with respect to any product candidate being researched or developed by or on behalf of any of the Santersus Companies, including

any action regarding any investigator participating in any such clinical research. Neither any Santersus Company nor, to the knowledge

of Santersus, any officer, employee or agent of any Santersus Company has been convicted of any crime or engaged in any conduct that has

previously caused or would reasonably be expected to result in, (i) disqualification or debarment by the FDA under 21 U.S.C. Sections

335(a) or (b), or any similar law, rule or regulation of any other Governmental Body, (ii) debarment, suspension, or exclusion by the

General Services Administration or any other Governmental Body or (iii) exclusion under 42 U.S.C. Section 1320a-7 or any similar law,

rule or regulation of any Governmental Body. None of the Santersus Companies and, to the knowledge of Santersus, no Representative of

any Santersus Company or Person acting in concert with or on behalf of the Santersus Companies, or any officers, employees or Representatives

of the same, has with respect to any product that is manufactured, tested, distributed, or held by or on behalf of any of the Santersus

Companies made an untrue statement of a material fact or fraudulent statement to the FDA or any other Governmental Body, failed to disclose

a material fact required to be disclosed to the FDA or any other Governmental Body, or committed an act, made a statement, or failed to

make a statement that, at the time such disclosure was made, would reasonably be expected to provide a basis for the FDA to invoke its

“Fraud, Untrue Statements of Material Facts, Bribery, and Illegal Gratuities” policy that is set forth in 56 Fed. Reg. 46191

(September 10, 1991) or for any other Governmental Body to invoke any similar policy (the “FDA Application Integrity Policy”).

Neither any Santersus Company nor any of its officers, employees, or to the knowledge of Santersus, any of its contractors or agents is

the subject of any pending or threatened investigation by FDA pursuant to the FDA Application Integrity Policy or by any other Governmental

Body pursuant to any similar policy. To the knowledge of Santersus, neither any Santersus Company nor any of its officers, employees,

contractors, and agents has committed any act, made any statement or failed to make any statement that would reasonably be expected to

provide a basis for FDA to invoke the FDA Application Integrity Policy or for any other Governmental Body to invoke a similar policy.

Neither any Santersus Company nor any of its officers, employees, or to the knowledge of Santersus, any of its contractors or agents has

made any materially false statements on, or material omissions from, any notifications, applications, reports and other submissions to

FDA or any other Governmental Body.

(i)

All nonclinical and clinical studies relating to product candidates, conducted by or on behalf of the Santersus Companies have

been, or are being, conducted in all material respects in compliance with the applicable requirements of the FDA’s Good Laboratory

Practice and Good Clinical Practice requirements, including regulations codified at 21 C.F.R. Parts 50, 54, 56, 58, and 812, as amended

from time to time, and all applicable similar requirements in other jurisdictions, including all requirements relating to protection of

human subjects participating in any such clinical studies; provided, however, that the foregoing representation and warranty

(i) is made only to Santersus’ knowledge with respect to clinical and nonclinical studies conducted by any third party on behalf

of the Santersus Companies and (ii) specifically excludes nonclinical studies that were not designed to be conducted in accordance with

Good Laboratory Practice. No Santersus Company has received any notices or correspondence from the FDA or any other Governmental Body

requiring the termination, suspension or material modification of any nonclinical study or clinical trial after initiation thereof by

or on behalf of a Santersus Company.

(j)

Each of the Santersus Companies has filed with the FDA, any other Governmental Body, and any institutional review board, all material

required notices, supplemental applications, and annual or other reports, including unanticipated adverse device effect reports, with

respect to each investigational device exemption or any comparable foreign regulatory application, related to the manufacture, testing,

or study of any of its product candidates, as applicable.

(k)

None of the Santersus Companies is a party to any corporate integrity agreement, monitoring agreement, consent decree, settlement

order, or similar agreement with or imposed by any Governmental Body. None of the Santersus Companies is subject to any investigation

that is pending or, to the knowledge of Santersus, that has been threatened by (i) the FDA pursuant to the Federal Food, Drug, and Cosmetic

Act (21 U.S.C. §301 et seq.) or (ii) the Department of Health and Human Services Office of Inspector General or Department

of Justice pursuant to the Federal Anti-Kickback Statute (42 U.S.C. §1320a-7b(b)) or the Federal Civil False Claims Act (31 U.S.C.

§3729), or any similar investigation that is pending or, to the knowledge of Santersus, that has been threatened by any other Governmental

Body pursuant to any other applicable Legal Requirements. Each Santersus Company is, and has at all times since January 1, 2023 been,

in compliance with all applicable Legal Requirements and contractual obligations regarding the privacy, protection, storage, use and disclosure

of Personal Data collected by such Santersus Company, except as would not, individually or in the aggregate, have a Santersus Material

Adverse Effect.

(l)

None of the Santersus Companies has received any FDA Form 483s, warning letters, untitled letters, cyber letters, notices of violation,

consent decrees, notices of investigation, indictments, sentencing memoranda, plea agreements, court orders, target or no-target letters,

proceedings, reviews (including data integrity reviews) or other notice of enforcement action from a Governmental Body.

(m)

Santersus has, prior to the execution of this Agreement, provided or made available to Company all information about serious adverse

events since January 1, 2023 obtained or otherwise received by any of the Santersus Companies from any source, in the United States or

outside the United States, related to its respective current product candidates. Santersus has disclosed to Company all material information

known by Santersus with respect to the safety and efficacy of the Santersus product candidates from nonclinical and/or clinical studies.

Each of the Santersus Companies has filed all annual and periodic reports, amendments and safety reports required to be made by a Santersus

Company for any Santersus product candidate or service required to be made to the FDA or any other Governmental Body.

2.10

Scientific Studies. The studies, tests, preclinical development and clinical trials, if any, conducted by or on behalf

of the Santersus Companies are being conducted in all material respects in accordance with experimental protocols, procedures and controls

pursuant to accepted professional and scientific standards for products or product candidates comparable to those being developed by the

Santersus Companies and all applicable Legal Requirements. The descriptions of, protocols for, and data and other results of, the studies,

tests, development and clinical trials related to any Santersus product candidate and conducted by or on behalf of the Santersus Companies

that have been furnished or made available to the Company are accurate and complete. To the knowledge of Santersus, no studies, tests,

development or trials exist, the results of which reasonably call into question the results of the studies, tests, development and trials

conducted by or on behalf of any Santersus Company.

2.11

Legal Proceedings; Orders.

(a)

Except as set forth on Part 2.11(a) of the Santersus Disclosure Schedules, as of the date of this Agreement, there is no

claim, action, suit, proceeding, arbitration, complaint, charge or investigation pending or currently threatened in writing: (i) against

any Santersus Company or any officer or director of any Santersus Company arising out of their capacity as an officer or director of such

Santersus Company; (ii) that involves any of the Santersus Companies, any business of any of the Santersus Companies or any of the assets

owned by any of the Santersus Companies; (iii) that questions the validity of this Agreement or the right of any Santersus Company to

enter into them, or to consummate the transactions contemplated by this Agreement; or (iv) that would reasonably be expected to have,

either individually or in the aggregate, a Santersus Material Adverse Effect. Neither any Santersus Company nor, to Santersus’ knowledge,

any of its officers or directors is a party or is named as subject to the provisions of any order, writ, injunction, judgment or decree

of any Governmental Body (in the case of officers or directors, such that arises out of their capacity as an officer or director of such

Santersus Company and as would affect any Santersus Company). There is no material action, suit, proceeding or investigation by any Santersus

Company pending or which any Santersus Company intends to initiate.

(b)

As of the date of this Agreement, there is no Order to which any of the Santersus Companies, or any of the assets owned or used

by any of the Santersus Companies, is subject. To the knowledge of Santersus, no officer or other key employee of any of the Santersus

Companies is subject to any Order that prohibits such officer or other employee from engaging in or continuing any conduct, activity or

practice relating to the business of any of the Santersus Companies.

(c)

No Santersus Company is insolvent or unable to pay its debts when due.

2.12

Brokers’ and Finders’ Fees. No broker, finder or investment banker is entitled to any brokerage, finder’s

or other fee or commission in connection with the Contemplated Transactions based upon arrangements made by or on behalf of any of the

Santersus Companies.

2.13

Employee Benefit Plans.

(a)

Part 2.13(a) of the Santersus Disclosure Schedule sets forth, as of the date hereof, a complete and accurate list of each

material plan, program, policy, Contract or other arrangement providing for employment, compensation, retirement, pension, nonqualified

deferred compensation, severance, separation, relocation, termination pay, performance awards, bonus, incentive compensation, stock option,

stock purchase, stock bonus, phantom stock, stock appreciation right, other equity-based award, supplemental retirement, profit sharing,

fringe benefits, reimbursement, cafeteria benefits, medical benefits, life insurance, disability benefits, accident benefits, salary continuation,

accrued leave, vacation, or other material employee benefits, whether written or unwritten, and each other “employee benefit plan”

within the meaning of Section 3(3) of the Employee Retirement Income Security Act of 1974, as amended (“ERISA”),

in each case, for current, retired or former employees, directors or consultants of any Santersus Company, which is sponsored, maintained,

contributed to, or required to be contributed to by any Santersus Company or with respect to which a Santersus Company has or is reasonably

likely to have any material Liability either directly or through a Santersus ERISA Affiliate as applicable (the (collectively, the “Santersus

Employee Plans”). The term “Santersus ERISA Affiliate” means any Person, trade or business, or other entity,

that at any relevant time is or was treated as a single employer with Santersus or any of its Subsidiaries pursuant to Section 414 of

the Code.

(b)

The Santersus Companies have made available to the Company true and complete copies of each Santersus Employee Plan and all material

related Santersus Employee Plan documents, Form 5500s for the three most recent plan years, nondiscrimination tests for the last three

plan years, and material correspondence with the IRS, DOL, or PBGC within the last six years. Each Santersus Employee Plan

has been maintained and administered in all material respects in accordance with its terms and in material compliance with the requirements

prescribed by applicable Legal Requirements (including, where applicable, ERISA and the Code). No Santersus Employee Plan promises

or provides retiree medical or other retiree life, disability or welfare benefits to any person, except to the extent required by Section

4980B of the Code or any similar state or non-U.S. Legal Requirement, the cost of which is fully paid by the participants. Each

Santersus Employee Plan that is subject to Code Section 409A has been administered and operated in documentary and operational compliance

with the requirements of Section 409A of the Code and no additional tax under Section 409A(a)(1)(B) of the Code has been or could reasonably

be expected to be incurred by a participant in any such Plan.

(c)

Neither any Santersus Company nor any Santersus ERISA Affiliate has ever maintained, established, sponsored, participated in or

contributed to, or is or has been obligated to contribute to, or otherwise incurred any Liability under, any “multiemployer plan”

(as defined in Section 3(37) of ERISA) or any “pension plan” (as defined in Section 3(2) and Section 3(35) of ERISA) subject

to Section 302 or Title IV of ERISA or Section 412 of the Code or any multiple employer plan under Section 413(c) of the Code, or any

multiple employer welfare arrangement within the meaning of Section 3(40) of ERISA or any voluntary employees’ beneficiary association

under Section 501(c)(9) of the Code.

(d)

Except as set forth on Part 2.13(d) of the Santersus Disclosure Schedule, no Santersus Company has in existence any share

or other incentive scheme other than those mentioned in the Santersus Shareholders Agreement or the Santersus Option Plan, whether settled

in cash or in securities of any kind. Except as set forth on Part 2.13(d) of the Santersus Disclosure Schedule, no Santersus Company

has any obligation to pay any bonus, settlement, gratification, compensation for unfair dismissal or similar payments to any present or

former employee or consultant. No Santersus Company has any obligation to make any severance, change-of-control or transaction or retention

bonus payment, or any payment of compensation for loss of office, employment, or redundancy to any present or former employee or director

as a consequence of the Contemplated Transactions.

(e)

Other than as specifically contemplated by this Agreement or as set forth on Part 2.13(e) of the Santersus Disclosure Schedule,

the consummation of the Contemplated Transactions will not, either alone or in combination with another event: (i) entitle any current

or former employee or other service provider of any Santersus Company to severance benefits or any other payment (including bonus payments);

(ii) accelerate the time of payment or vesting of any such payments or benefits or increase the amount of compensation or benefits due

any such employee or service provider; (iii) result in the forgiveness of any indebtedness; or (iv) result in any obligation to fund future

benefits under any Santersus Employee Plan.

(f)

No Santersus Company has made any representations regarding equity incentives to any officer, employee, director or consultant

that are inconsistent with the share amounts and terms set forth in the minutes of meetings provided to Company.

(g)

On or prior to the date hereof, the Santersus Companies have taken all actions necessary or advisable to assure that upon the consummation

of the transactions contemplated by Section 6.15, the Company shall acquire, or Santersus shall have the right to acquire on the

Company’s behalf, all Santersus Ordinary Shares issuable upon the exercise of the Santersus Options, free and clear of any Encumbrance.

(h)

Neither the execution of this Agreement, nor the consummation of the Acquisition, either alone or in combination with another event

will, result in the receipt or retention (i) by any person who is a “disqualified individual” (within the meaning of Section

280G of the Code) with respect to any Santersus Company of any payment or benefit that is characterized as a “parachute payment”

(within the meaning of Section 280G of the Code), determined without regard to the application of Section 280G(b)(5) of the Code or (ii)

any amount the deduction for which would be disallowed under Section 162(m) of the Code.

(i)

Each Santersus Employee Plan providing for deferred compensation that constitutes a “nonqualified deferred compensation plan”

(as defined in Section 409A(d)(1) of the Code and the regulations promulgated thereunder) is, and has been, established, administered

and maintained in material compliance in both form and operation with the requirements of Section 409A of the Code and the regulations

promulgated thereunder.

(j)

No Person has any “gross up” agreements with any Santersus Company or other assurance of reimbursement or indemnity

by any Santersus Company for any Taxes imposed under Section 409A or Section 4999 of the Code.

2.14

Title to Assets; Real Property. Except as set forth on Part 2.14 of the Santersus Disclosure Schedule, the Santersus

Companies own, and have good, valid and marketable title to, all material tangible assets purported to be owned by them, including all

material tangible assets reflected in the books and records of the Santersus Companies as being owned by the Santersus Companies. All

of said assets are owned by the Santersus Companies free and clear of any Encumbrances, except for Permitted Encumbrances and as set forth

on Part 2.14 of the Santersus Disclosure Schedule. The Santersus Companies are the lessees of, and hold valid leasehold interests

in, all assets purported to have been leased by them, including all assets reflected in the books and records of the Santersus Companies

as being leased to the Santersus Companies, and the Santersus Companies enjoy undisturbed possession of such leased assets. The Santersus

Companies do not own and have never owned any real property or any interest in real property, except for the leaseholds created under

the real property leases identified on Part 2.14 of the Santersus Disclosure Schedule. Part 2.14 of the Santersus Disclosure

Schedule sets forth a complete and accurate list of all real property leases to which any Santersus Company is a party, which are each

in full force and effect, and with no existing default thereunder, except as would not be reasonably expected to have a Santersus Material

Adverse Effect.

2.15

Environmental Matters. Each Santersus Company is in compliance with all applicable foreign, federal, state and local

laws and regulations relating to the protection of human health and safety, the environment or hazardous or toxic substances or wastes,

pollutants or contaminants (“Environmental Laws”), which compliance includes the possession by Santersus of

all permits and other authorizations required under applicable Environmental Laws and compliance with the terms and conditions thereof,

except where the failure to be in compliance would not, individually or in the aggregate, have a Santersus Material Adverse Effect. Since

January 1, 2023, no Santersus Company has received any written notice or other communication (in writing or otherwise), whether from a

Governmental Body, citizens group, employee or otherwise, that alleges that any Santersus Company is not in compliance in all material

respects with any Environmental Law, and, to the knowledge of Santersus, there are no circumstances existing as of the date hereof that

would prevent or interfere with any Santersus Company’s compliance in all material respects with any Environmental Law in the future.

To the knowledge of Santersus: (i) no current or prior owner of any property leased or controlled by any Santersus Company has received

any written notice or other communication (in writing) relating to property owned or leased at any time by any Santersus Company, whether

from a Governmental Body, citizens group, employee or otherwise, that alleges that such current or prior owner or any Santersus Company

is not in compliance in all material respects with or has violated any Environmental Law relating to such property; and (ii) no Santersus

Company has any material liability under any Environmental Law.

2.16

Labor Matters.

(a)

Part 2.16(a) of the Santersus Disclosure Schedule sets forth a true, complete and correct list as of the date of this Agreement

of all Santersus Personnel along with each such employee’s position, whether classified as exempt or non-exempt for wage and hour

purposes, business location, status (i.e., active or inactive and if inactive, the type of leave and estimated duration), immigration

status, hire date, actual compensation and annual rate of compensation as of the date hereof (including base salary and the target amount

of any bonuses to which such employee may be eligible) and the total amount of bonus, retention, severance and other amounts to be paid

to such employee at the Closing or otherwise in connection with the Acquisition. All employment agreements between the Santersus Companies

and their employees are in writing and contain all terms and conditions applicable to the respective employment relationship.

(b)

The Santersus Companies are not bound by or subject to (and none of its assets or properties is bound by or subject to) any written

or oral, express or implied, contract, commitment or arrangement with any labor union, and no labor union has requested or, to the knowledge

of Santersus, has sought to represent any of the employees, representatives or agents of any Santersus Company. There is no strike or

other labor dispute involving any Santersus Company pending, or to Santersus’ knowledge, threatened, which could have a Santersus

Material Adverse Effect, nor, to the knowledge of Santersus, is there any labor organization activity involving the Santersus Personnel.

(c)

The Santersus Companies and each of their respective employees complied with all obligations imposed by all relevant Legal Requirements

and collective labor agreements. The Santersus Companies have (i) maintained adequate up-to-date records, and retained records regarding

their service and engagement, their hours of work and rest breaks, their right to work and, where Santersus Personnel are sponsored by

any Santersus Company in accordance with immigration legislation, their contact details and absence records and (ii) complied with all

contractual obligations towards Santersus Personnel. Santersus has applied for and is in possession of all relevant governmental authorizations

for the conduct of all work activities of its employees as presently conducted and as expected to be conducted, in Switzerland and abroad.

(d)

Except as set forth on Part 2.16(d) of the Santersus Disclosure Schedules, no material salary increases have been resolved

but not yet implemented. Any claims of current or former Santersus Personnel, including any claims for compensation, bonus, gratification,

expenses, overtime, and holidays, as well as compensation for unfair dismissal, are fully provided for in the Santersus Financials as

per the respective accounts date. No employee has received a bonus for three consecutive years without the relevant Santersus Company

expressly reserving the discretionary nature of said payment in its bonus communication(s).

(e)

To Santersus’ knowledge, none of the Santersus Personnel are obligated under any contract (including licenses, covenants

or commitments of any nature) or other agreement, or subject to any judgment, decree or order of any court or administrative agency, that

would materially interfere with such employee’s ability to promote the interest of such employee’s respective employer or

that would conflict with any Santersus Company’s business. Neither the execution or delivery of this Agreement, nor the carrying

on of any Santersus Company’s business by the Santersus Personnel, nor the conduct of any Santersus Company as now conducted and

as presently proposed to be conducted, will, to Santersus’ knowledge, conflict with or result in a breach of the terms, conditions,

or provisions of, or constitute a default under, any contract, covenant or instrument under which any Santersus Personnel is now obligated.

(f)

None of the Santersus Companies are delinquent in payments to any of their employees, consultants, or independent contractors,

for any wages, salaries, commissions, bonuses, or other direct compensation for any service performed for them to the date hereof or amounts

required to be reimbursed to such employees, consultants or independent contractors. Except as set forth on Part 2.16(f) of the

Santersus Disclosure Schedules, each Santersus Company has complied in all material respects with all applicable Legal Requirements of

Switzerland, including those related to wages, hours, worker classification and collective bargaining. Each Santersus Company has withheld

and paid to the appropriate governmental entity or is holding for payment not yet due to such Governmental Body all amounts required to

be withheld from employees of such Santersus Company and is not liable for any arrears of wages, taxes, penalties or other sums for failure

to comply with any of the foregoing.

(g)

To Santersus’ knowledge, no officer intends to terminate employment with any Santersus Company or is otherwise likely to

become unavailable to continue as an employee. No Santersus Company has the present intention to terminate the employment of any of the

foregoing. The employment of each employee of each Santersus Company is terminable at the will of such Santersus Company. Except as set

forth in the Santersus Disclosure Schedule or as required by law, upon termination of the employment of any such employees, no severance

or other payments will become due. Except as set forth in the Santersus Disclosure Schedule, no Santersus Company has any policy, practice,

plan or program of paying severance pay or any form of severance compensation in connection with the termination of employment services.

(h)

To Santersus’ knowledge, none of the officers or directors of any Santersus Company has been: (i) subject to voluntary or

involuntary petition under the federal bankruptcy Legal Requirements or any state insolvency Legal Requirement or the appointment of a

receiver, fiscal agent or similar officer by a court for such person’s business or property; (ii) convicted in a criminal proceeding

or named as a subject of a pending criminal proceeding (excluding traffic violations and other minor offenses); (iii) subject to any order,

judgment or decree (not subsequently reversed, suspended, or vacated) of any court of competent jurisdiction permanently or temporarily

enjoining such person from engaging, or otherwise imposing limits or conditions on such person’s engagement in any securities, investment

advisory, banking, insurance, or other type of business or acting as an officer or director of a public company; or (iv) found by a court

of competent jurisdiction in a civil action or by the SEC or the Commodity Futures Trading Commission to have violated any federal or

state securities, commodities, or unfair trade practices law, which such judgment or finding has not been subsequently reversed, suspended,

or vacated.

(i)

No Legal Proceedings are as of the date of this Agreement open and pending (or within the past three years have been settled or

otherwise closed) against any Santersus Company with respect to the employment of, or failure to employ, any individual, including any

brought with or by the Equal Employment Opportunity Commission, the Office of Federal Contract Compliance Programs, or other applicable

Governmental Body regulating the employment or compensation of individuals (or, with respect to discrimination, unlawful harassment, retaliation,

or similar wrongdoing, pursuant to internal complaint procedures), and no Santersus Personnel has made, within the past three years a

written complaint of discrimination, unlawful harassment, retaliation, or other similar wrongdoing or, to the Knowledge of Santersus,

within the past three years, an oral complaint. Within the last three years, no Santersus Company has received any requests for, or conducted,

an internal investigation of any officer, manager, or supervisor of any Santersus Personnel with respect to any claims with respect to

discrimination, unlawful harassment, retaliation, or other similar wrongdoing.

(j)

Within the past three (3) years, no Santersus Company has caused (i) a plant closing as defined in the Worker Adjustment and Retraining

Notification Act (the “WARN Act”) affecting any single site of employment of any Santersus Company or one or

more operating units within any site of employment of any Santersus Company or (ii) a mass layoff as defined in the WARN Act, nor has

any Santersus Company been affected by any transaction or engaged in layoffs or employment terminations sufficient in number to trigger

application of any similar foreign, state or local Law.

(k)

Part 2.16(k) of the Santersus Disclosure Schedule sets forth each Person retained by any Santersus Company as an individual

consultant or independent contractor since January 1, 2023 and further sets forth the following information with respect to each: (i)

name, (ii) services provided, (iii) date of engagement (iv) the entity or entities to which the individual provides services, (v) fees

paid or payable to the individual, and (vi) service location (including city, state, and country). No Santersus Company retains, and has

retained in the past, any consultants or freelancers that could be requalified as employees under applicable laws under applicable Legal

Requirements.

(l)

Each current and former employee, consultant and officer of each Santersus Company involved in the development of Santersus IP

Rights is or was, when being occupied to the benefit of the relevant Santersus Company, bound by appropriate undertakings to ensure the

assignment to the relevant Santersus Company of any IP Rights developed by such person.

2.17

Santersus Contracts.

(a)

Part 2.17 of the Santersus Disclosure Schedule lists each of the following Contracts in effect as of the date of this Agreement

to which any Santersus Company is a party or by which any Santersus Company is bound:

(i)

any Contract incorporating or relating to any warranty, any sharing of Liabilities or any indemnity not entered into in the ordinary

course of business, including any indemnification agreements between a Santersus Company and any of its officers or directors;

(ii)

any Contract imposing any material restriction on the right or ability of any Santersus Company: (A) to compete with any other

Person; (B) to acquire any product or other asset or any services from any other Person; (C) to develop, sell, supply, distribute, offer,

support or service any product or any technology or other asset to or for any other Person; (D) to perform services for any other Person;

or (E) to otherwise transact business with any other Person;

(iii)

any Contract containing “most favored” provisions, board of directors observer rights, or other side letter agreements

not otherwise disclosed pursuant to any other representation;

(iv)

any Contract relating to the acquisition of any material interest in, or any material amount of, property or assets of any Santersus

Company, other than in the ordinary course of business, or any ownership interest in any corporation, partnership, joint venture or other

business enterprise;

(v)

any joint marketing or collaboration Contract;

(vi)

any Contract containing obligations (contingent or otherwise) of, or payments to, any Santersus Company in excess of CHF 100,000

(other than employment agreements and offer letters or other engagements with individual service providers);

(vii)

any Contract that provides for: (A) any right of first refusal, right of first negotiation, right of first notification or similar

right with respect to any securities or assets of any Santersus Company; or (B) any “no shop” provision or similar exclusivity

provision with respect to any securities or assets of any Santersus Company;

(viii)

any Contract containing the grant of rights to manufacture, produce, assemble, license, market, or sell its products to any other

Person that limits any Santersus Company’s exclusive right to develop, manufacture, assemble, distribute, market or sell such Santersus

Company’s products;

(ix)

any Contract for university licenses;

(x)

any Contract providing any severance or change-in-control payment or benefit to any officer, director or employee of any Santersus

Company;

(xi)

any Contract with any Governmental Body that is material to the business or operations of the Santersus Companies;

(xii)

any interested party Contracts;

(xiii)

any Contract containing any royalty, dividend or similar arrangement based on the revenues or profits of any Santersus Company

or any of its Subsidiaries;

(xiv)

any Contract for leased real property;

(xv)

any Contract with any financial advisor, broker, finder, investment bank or other Person, providing advisory services;

(xvi)

any Contract that is not terminable by Santersus with no more than ninety (90) days prior notice to the other party (with no penalty

or payment) by Santersus and (A) which involves payment or receipt by any Santersus Company after the date of this Agreement under any

such Contract of more than CHF 100,000 in the aggregate, or obligations after the date of this Agreement in excess of CHF 100,000 in the

aggregate or (B) that is material to the business or operations of the Santersus Companies; or

(xvii)

any Contract not entered into in the ordinary course of business that contemplates or involves the payment or delivery of cash

or other consideration in an amount or having a value in excess of CHF 100,000 in the aggregate, or contemplates or involves the performance

of services having a value in excess of CHF 100,000 in the aggregate, other than any arrangement or agreement expressly contemplated by

or provided for under this Agreement.

(b)

Santersus has made available to Company an accurate and complete copy of each Contract listed or required to be listed on Part

2.17 of the Santersus Disclosure Schedule (any such Contract, an “Santersus Contract”). There are no Santersus

Contracts that are not in written form. No Santersus Company and, to Santersus’ knowledge, no other party to a Santersus Contract

has breached or violated in any material respect or materially defaulted under, or received notice that it has breached, violated or defaulted

under, in any material respects, any of the terms or conditions of any of the Santersus Contracts. To the knowledge of Santersus, no event

has occurred, and no circumstance or condition exists, that (with or without notice or lapse of time or both) would reasonably be expected

to: (i) result in a violation or breach in any material respect of any of the provisions of any Santersus Contract; (ii) give any Person

the right to declare a default in any material respect under any Santersus Contract; (iii) give any Person the right to receive or require

a rebate, chargeback, penalty or change in delivery schedule under any Santersus Contract; (iv) give any Person the right to accelerate

the maturity or performance of any Santersus Contract; or (v) give any Person the right to cancel, terminate or modify any Santersus Contract.

The consummation of the Acquisition will not (either alone or upon the occurrence of additional acts or events) result in any material

payment or payments becoming due from any Santersus Company to any Person under any Santersus Contract or give any Person the right to

terminate or alter the provisions of any Santersus Contract. No Person is renegotiating any material amount paid or payable to any Santersus

Company under any Santersus Contract or any other material term or provision of any Santersus Contract. Each Santersus Contract is valid,

binding, enforceable and in full force and effect, and will continue to be valid, binding, enforceable and in full force and effect following

the Closing and the consummation of the Acquisition, except as enforceability may be limited by bankruptcy and other similar laws and

general principles of equity.

2.18

Insurance.

(a)

Except as set forth on Part 2.18(a) of the Santersus Disclosure Schedules, each of the Santersus Companies’ insurance

policies (including, as applicable, fire, theft, cyber, casualty, general liability, workers compensation, business interruption, environmental,

product liability, clinical trial and automobile insurance policies and bond and surety arrangements, collectively “Insurance

Policies”) are in full force and effect on the date hereof and are maintained with reputable companies against loss relating

to the business, operations and properties and such other risks as companies engaged in similar business as the Santersus Companies would,

in accordance with good business practice, customarily insure. All premiums due and payable under such Insurance Policies have been paid

on a timely basis and each Santersus Company is in compliance in all material respects with all other terms thereof. True, complete and

correct copies of such Insurance Policies have been made available to Company.

(b)

There are no material claims pending, under any Insurance Policy to which any Santersus Company is a party, as to which coverage

has been questioned, denied or disputed. All material claims thereunder have been filed in a due and timely fashion in all material respects

and since January 1, 2023 no Santersus Company has been refused insurance for which it has applied or had any policy of insurance terminated

(other than at its request), nor has any Santersus Company received written notice from any insurance carrier that: (i) such insurance

will be canceled or that coverage thereunder will be materially reduced or eliminated; or (ii) premium costs with respect to such insurance

will be materially increased, other than premium increases in the ordinary course of business applicable on their terms to all holders

of similar policies.

2.19

Interested Party Transactions.

(a)

Other than (i) standard employee benefits generally made available to all employees, standard employee offer letters and Confidential

Information Agreements; (ii) standard director and officer indemnification agreements approved by the board of directors of Santersus;

(iii) the purchase of shares of a Santersus Company’s capital stock and the issuance of options to purchase shares of Santersus’

Common Shares, in each instance, approved in the written minutes of the board of directors of Santersus (which has been made available

to Company); (iv) as set forth in Part 2.19(a) of the Santersus Disclosure Schedule; and (v) this Agreement, there are no agreements,

understandings or proposed transactions, whether written or oral, between any Santersus Company and (i) any of the Sellers, (ii) its officers

or directors, or (iii) any Affiliate of any of the foregoing.

(b)

No Santersus Company is indebted, directly or indirectly, to any of the Sellers, its directors, officers or employees or to their

respective spouses or children or to any Affiliate of any of the foregoing, other than in connection with expenses or advances of expenses

incurred in the ordinary course of business or employee relocation expenses and for other customary employee benefits made generally available

to all employees.

(c)

Other than as set forth in Part 2.19(c) of the Santersus Disclosure Schedule, none of the Santersus Companies’ directors,

officers or employees or, to the knowledge of Santersus, any members of their immediate families, or any Affiliate of the foregoing are,

directly or indirectly, indebted to any Santersus Company or, to the knowledge of Santersus, have any (i) material commercial, industrial,

banking, consulting, legal, accounting, charitable or familial relationship with any Santersus Company or any of any Santersus Company’s

customers, suppliers, service providers, joint venture partners, licensees and competitors, (ii) direct or indirect ownership interest

in any firm or corporation with which any Santersus Company is affiliated or with which any Santersus Company has a business relationship,

or any firm or corporation which competes with any Santersus Company except that directors, officers, employees or stockholders of any

Santersus Company may own stock in (but not equal to or exceeding 5% of the outstanding capital stock of) publicly traded companies that

may compete with any Santersus Company or (iii) financial interest in any material contract with any Santersus Company.

2.20

Disclosure; Company Information. None of the information supplied or to be supplied by or on behalf of Santersus for

inclusion or incorporation by reference in the Proxy Statement or Registration Statement will, at the time the Proxy Statement or Registration

Statement, as applicable, is filed with the SEC, at any time it is amended or supplemented, or at the time it becomes effective under

the Securities Act, contain any statement that, in light of the circumstances under which it was made, is false or misleading with respect

to any material fact or omit to state any material fact necessary in order to correct any statement of a material fact in any earlier

communication with respect to the solicitation of proxies for the Company Stockholders’ Meeting which has become false or misleading.

None of the information supplied or to be supplied by or on behalf of Santersus for inclusion or incorporation by reference in the Proxy

Statement will, at the time the Proxy Statement is first mailed to the Company Stockholders or at the time of the Company Stockholders’

Meeting, contain any statement that, in light of the circumstances under which it was made, is false or misleading with respect to any

material fact or omit to state any material fact necessary in order to correct any statement of a material fact in any earlier communication

with respect to the solicitation of proxies for the Company Stockholders’ Meeting which has become false or misleading. Notwithstanding

the foregoing, no representation is made by Santersus with respect to the information that has been or will be supplied by any of the

Acquiring Companies, any Seller or any of their respective Representatives for inclusion in the Proxy Statement.

2.21

Anti-Takeover Statutes Not Applicable. The board of directors of Santersus has taken all actions so that no takeover

statute or similar Legal Requirement related to business combinations applies or purports to apply to the execution, delivery or performance

of this Agreement or to the consummation of the Contemplated Transactions.

2.22

Ownership of Company Common Stock. None of the Santersus Companies own, directly or indirectly, beneficially or of record,

any shares of Company Common Stock or any other economic interest (through derivative securities or otherwise) in, Company. Other than

as contemplated by this Agreement, none of the Santersus Companies are, nor at any time during the last three (3) years have they been,

an “interested stockholder” of Company within the meaning of Nevada Revised Statutes 78.411-78.444 .

2.23

Exclusivity of Representations; Reliance.

(a)

Except as expressly set forth in this Article 2, neither Santersus nor any Person on behalf of Santersus has made, nor are

any of them making, any representation or warranty, written or oral, express or implied, at law or in equity, including with respect to

merchantability or fitness for any particular purpose, in respect of Santersus or its business in connection with the Contemplated Transactions,

including any representations or warranties about the accuracy or completeness of any information or documents previously provided (including

with respect to any financial or other projections therein), and any other such representations and warranties are hereby expressly disclaimed.

(b)

Santersus acknowledges and agrees that, except for the representations and warranties of Company set forth in Article 3,

neither Santersus nor its Representatives is relying on any other representation or warranty of Company, or any other Person made outside

of Article 3, including regarding the accuracy or completeness of any such other representations or warranties or the omission

of any material information, whether express or implied, in each case with respect to the Contemplated Transactions.

Article

REPRESENTATIONS AND WARRANTIES OF COMPANY

Company represents and warrants

to Santersus and Sellers as follows (it being understood that each representation and warranty contained in this Article 3 is subject

to: (a) the exceptions and disclosures set forth in the part or subpart of the Company Disclosure Schedule corresponding to the particular

Section or subsection in this Article 3 in which such representation and warranty appears; (b) any exceptions or disclosures explicitly

cross-referenced in such part or subpart of the Company Disclosure Schedule by reference to another part or subpart of the Company Disclosure

Schedule; and (c) any exception or disclosure set forth in any of the Company Reports and publicly available on the SEC’s Electronic

Data Gathering Analysis and Retrieval system (but (i) solely to the extent that any information is reasonably apparent from a review of

such Company Reports, (ii) without giving effect to any amendment thereof filed with, or furnished to the SEC on or after the date hereof

and (iii) excluding any disclosures contained under the heading “Risk Factors” and any disclosure of risks included in any

“forward-looking statements” disclaimer or in any other section to the extent they are forward-looking statements or cautionary,

predictive or forward-looking in nature) or other part or subpart of the Company Disclosure Schedule to the extent it is reasonably apparent

from the wording of such exception or disclosure that such exception or disclosure qualifies such representation and warranty):

3.1

Organization and Qualification; Charter Documents.

(a)

Part 3.1(a) of the Company Disclosure Schedule identifies each Subsidiary of Company and indicates its jurisdiction of organization.

No Acquiring Company owns any capital stock of, or any equity interest of any nature in, any other Entity, other than the Entities identified

on Part 3.1(a) of the Company Disclosure Schedule. None of the Acquiring Companies has agreed or is obligated to make, or is bound

by any Contract under which it may become obligated to make, any future equity investment in or capital contribution to any other Entity,

other than the Entities identified on Part 3.1(a) of the Company Disclosure Schedule.

(b)

Each Acquiring Company is duly organized, validly existing under the laws of its jurisdiction of organization, formation or incorporation,

as applicable, and in good standing (to the extent such concept is recognized in their respective jurisdictions) under the laws of the

jurisdiction in which it is chartered or organized with full corporate power and authority: (i) to conduct its businesses in the manner

in which its business is currently being conducted and presently proposed to be conducted; (ii) to own and use its assets in the manner

in which its assets are currently owned and used; and (iii) to perform its obligations under all Company Contracts by which it is bound,

except where the failure to have such corporate power and authority would not, individually or in the aggregate, have a Company Material

Adverse Effect. The Organizational Documents of each Acquiring Company, copies of which are publicly available SEC Documents, are true,

correct and complete and no Acquiring Company is in violation of any provision thereof in any material respect.

(c)

The copy of the minute books of the Acquiring Companies made available to Santersus reflects, in all material respects, the minutes

of all meetings of directors and stockholders and all actions by written consent without a meeting by the directors and stockholders since

January 1, 2023 of each Acquiring Company and accurately reflects in all material respects all actions by the directors (and any committee

of directors) and stockholders of each Acquiring Company.

3.2

Capital Structure.

(a)

As of the close of business on September 11, 2026, the authorized capital stock of Company consists of (i) 10,000,000 shares of

Company Common Stock, of which 2,343,181 shares of Company Common Stock were issued and outstanding, and (ii) 10,000,000 shares of preferred

stock, par value $0.001, of which 1,000,000 shares of Company Preferred Stock are designated as Series A preferred stock (the “Company

Series A Preferred Stock”) and 2,500,000 shares of Company Preferred Stock are designated as Series B Preferred Stock of

the Company, par value $0.001 per share (the “Company Series B Preferred Stock,” and, together with the Company

Series A Preferred Stock, the “Company Preferred Stock”) and 6,500,000 shares of Company Preferred Stock are

undesignated. There were 970,000 shares of Company Series A Preferred Stock previously issued, and no shares of Company Series A Preferred

Stock were issued and outstanding as of the close of business on September 11, 2026 and there were 2,454,545 shares of Company Series

B Preferred Stock previously issued, of which no shares of Company Series B Preferred Stock were issued and outstanding as of the close

of business on September 11, 2026. No shares of capital stock are held in Company’s treasury. All outstanding shares of Company

Common Stock are duly authorized, validly issued, fully paid and non-assessable and were issued in compliance with all applicable Legal

Requirements.

(b)

As of the close of business on September 11, 2026, Company had reserved (i) an aggregate of 245,148 shares of Company Common Stock

for issuance under the Company Option Plan, under which options were outstanding for an aggregate of 114,059 shares and Company Restricted

Stock were outstanding for an aggregate of 93,000 shares and (ii) no shares of Company Common Stock for issuance to holders of warrants

to purchase Company Common Stock upon their exercise. Part 3.2(b) of the Company Disclosure Schedule lists, as of the close of

business on September 11, 2026, each outstanding Company Option and Company Restricted Stock, the name of the holder of such option or

restricted stock, the number of shares of restricted stock or number of shares subject to such option, the exercise price of such option,

the vesting schedule and termination date of such option or restricted stock, and whether the exercisability of such option or vesting

or settlement of such restricted stock will be accelerated in any way by the Contemplated Transactions. No further Company Options may

be granted under the Company Option Plan after the date hereof. All shares of Company Common Stock subject to issuance as aforesaid, upon

issuance on the terms and conditions specified in the instruments pursuant to which they are issuable, would be duly authorized, validly

issued, fully paid and non-assessable. Each Company Option was granted with an exercise price not less than the fair market value of a

share of Company Common Stock on the date such option was approved by the board of directors of Company or an authorized committee thereof.

All outstanding options to purchase Company Common Stock were granted under the Company Option Plan, except as set forth on Part 3.2(b)

of the Company Disclosure Schedule.

(c)

As of the close of business on September 11, 2026, the Company had no Company Warrants outstanding and no shares of Company Common

Stock reserved for issuance of any such Company Warrants.

(d)

Except as set forth on Part 3.2(d) of the Company Disclosure Schedule, (i) none of the outstanding shares of Company Common

Stock are entitled or subject to any preemptive right, right of repurchase or forfeiture, right of participation, right of maintenance

or any similar right, except for any such rights as have been effectively waived; (ii) none of the outstanding shares of Company Common

Stock are subject to any right of first refusal in favor of Company; (iii) there are no outstanding bonds, debentures, notes or other

indebtedness of the Acquiring Companies having a right to vote on any matters on which the Company Stockholders have a right to vote;

(iv) there is no Contract to which the Acquiring Companies are a party relating to the voting or registration of, or restricting any Person

from purchasing, selling, pledging or otherwise disposing of (or from granting any option or similar right with respect to), any shares

of Company Common Stock; and (v) none of the Acquiring Companies is under any obligation, or is bound by any Contract pursuant to which

it may become obligated, to repurchase, redeem or otherwise acquire any outstanding shares of Company Common Stock or other securities,

and there are no shares of Company Common Stock outstanding that are subject to a risk of forfeiture or other similar condition under

any applicable restricted stock purchase agreement.

3.3

Authority; Non-Contravention; Approvals.

(a)

Company has the requisite corporate power and authority to enter into this Agreement and, subject to Company Stockholder Approval,

to perform its obligations hereunder and to consummate the Contemplated Transactions. The execution and delivery of this Agreement by

Company, the performance by Company of its obligations hereunder and the consummation by Company of the Contemplated Transactions have

been duly authorized by all necessary corporate action on the part of Company, subject only to Company Stockholder Approval. The Company

Stockholder Approval Threshold is the only vote of the holders of any class or series of Company Common Stock necessary to approve the

Company Stockholder Approval Matters (collectively, “Company Stockholder Approval”). Except for Company Stockholder

Approval, no other corporate proceeding on the part of Company is necessary to authorize the adoption, execution, delivery and performance

of this Agreement or to consummate the Acquisition. This Agreement has been duly executed and delivered by Company and, assuming the due

authorization, execution and delivery by Santersus and Sellers, constitutes the valid and binding obligation of Company, enforceable in

accordance with its terms, subject to applicable bankruptcy, insolvency, fraudulent transfer, reorganization, moratorium and other laws

affecting creditors’ rights generally and general principles of equity.

(b)

Company’s Special Committee, by resolutions duly adopted by vote at a meeting of all directors of Company duly called and

held and, as of the date hereof, not subsequently rescinded or modified in any way, has, as of the date hereof (i) approved, adopted and

declared advisable this Agreement and the Acquisition, and determined that this Agreement and the Contemplated Transactions, including

the Acquisition, are fair to and in the best interests of the Company Stockholders and (ii) approved the Company Stockholder Approval

Matters that require board approval and resolved to recommend that the Company Stockholders approve the Company Stockholder Approval Matters,

and directed that such matters be submitted for consideration of the Company Stockholders.

(c)

The execution and delivery of this Agreement by Company does not, and the performance of this Agreement by Company will not, subject

to obtaining the Company Stockholder Approval and compliance with the requirements set forth in Section 3.3(d) below, (i) conflict

with or violate the Organizational Documents of the Company, (ii) conflict with or violate any Legal Requirement applicable to the Acquiring

Companies or by which its or any of their respective properties are bound or affected or (iii) require an Acquiring Company to make any

filing with or give any notice to a Person or to obtain any Consent from a Person, or result in any breach of or constitute a default

(or an event that with notice or lapse of time or both would become a default) under, or impair Company’s rights or alter the rights

or obligations of any third party under, or give to others any rights of termination, amendment, acceleration or cancellation of, or result

in the creation of a lien or encumbrance on any of the properties or assets of the Acquiring Companies pursuant to, any Company Contract

to which an Acquiring Company is a party or by which any Acquiring Company or any of its properties are bound or affected (except, for

purposes of clause (ii) and (iii), as would not, individually or in the aggregate, have a Company Material Adverse Effect).

(d)

No consent, approval, order or authorization of, or registration, declaration or filing with, any Governmental Body is required

by or with respect to Company in connection with the execution and delivery of this Agreement or the consummation of the Contemplated

Transactions, except for (i) the filings contemplated by Section 6.4(a), (ii) the filing of current reports on Form 8-K with the

SEC and (iii) such approvals as may be required under applicable state securities or “blue sky” Legal Requirements or the

rules and regulations of Nasdaq.

3.4

Anti-Takeover Statutes. Subject to the accuracy of Santersus’ representations in Section 2.22 and each

Seller’s representations in Section 4.5, the board of directors of Company has taken all actions so that no state takeover

statute or similar Legal Requirement, including (to the extent applicable) the Nevada “combination with interested stockholders”

statute (NRS 78.378 through 78.3793) or the Nevada “acquisition of controlling interest” statute (NRS 78.411 through 78.444),

the restrictions on business combinations provided for therein, applies or purports to apply to the execution, delivery or performance

of this Agreement or to the consummation of the Contemplated Transactions, except as would not, individually or in the aggregate, reasonably

be expected to have a Company Material Adverse Effect.

3.5

SEC Filings; Company Financial Statements; No Undisclosed Liabilities.

(a)

Since January 1, 2024, all SEC Documents (such SEC Documents, the “Company Reports”) have been timely

filed and, as of the time a Company Report was filed with the SEC (or, if amended or superseded by a filing prior to the date hereof,

then on the date of such filing): (i) each of the Company Reports complied in all material respects with the applicable requirements of

the Securities Act or Exchange Act (as the case may be) and (ii) none of the Company Reports contained any untrue statement of a material

fact or omitted to state a material fact required to be stated therein or necessary in order to make the statements therein, in the light

of the circumstances under which they were made, not misleading; provided, however, that no representation is made as to

the accuracy of any financial projections or forward-looking statements, or as to the completeness of any information furnished by the

Company to the SEC solely for the purpose of complying with Regulation FD promulgated under the Exchange Act. Each of the certifications

and statements relating to the Company Reports required by Rule 13a-14 or 15d-14 under the Exchange Act or 18 U.S.C. §1350

(Section 906 of the Sarbanes-Oxley Act) is accurate and complete, and complied as to form and content with all applicable Legal Requirements

in effect at the time such certification was filed with or furnished to the SEC by Company. As used in this Section 3.5, the term

“file” and variations thereof will be broadly construed to include any manner in which a document or information is furnished,

supplied or otherwise made available to the SEC.

(b)

There is and since January 1, 2024 there has been no failure on the part of Company and any of Company’s directors or officers,

in their capacities as such, to comply with any provision of the Sarbanes-Oxley Act of 2002, as amended, and the rules and regulations

promulgated in connection therewith (the “Sarbanes-Oxley Act”), that are in effect and with which Company is

required to comply as of the date of this Agreement.

(c)

As of the date of this Agreement, there are no outstanding or unresolved comment letters from the staff of the SEC relating to

the Company Reports, and the SEC has not advised Company that any final responses are inadequate, insufficient or otherwise non-responsive.

Company has made available to Santersus true, correct and complete copies of all comment letters, written inquiries and enforcement correspondence

between the SEC, on one hand, and Company and any of its Subsidiaries, on the other hand, occurring since January 1, 2024.

(d)

Company maintains “disclosure controls and procedures” (as such term is defined in Rule 13a-15(e) under the Exchange

Act), reasonably designed to ensure that all information (both financial and non-financial) required to be disclosed by Company in the

reports that it files or submits under the Exchange Act is recorded, processed, summarized and reported within the time periods specified

in the rules and forms of the SEC and that all such information required to be disclosed is accumulated and communicated to the management

of Company, as appropriate, to allow timely decisions regarding required disclosure and to enable the principal executive officer and

principal financial officer of Company to make the certifications required under the Exchange Act with respect to such reports, except

as set forth on Part 3.5(d) of the Company Disclosure Schedule.

(e)

Acquiring Companies, considered together as one entity, maintain a system of internal accounting controls (as contemplated under

Rule 13a-15(f) of the Exchange Act) designed to provide reasonable assurance that: (i) transactions are executed in accordance with management’s

general or specific authorizations; (ii) transactions are recorded as necessary to permit preparation of financial statements in conformity

with GAAP and to maintain asset accountability; (iii) access to assets is permitted only in accordance with management’s general

or specific authorization; and (iv) the recorded accountability for assets is compared with the existing assets at reasonable intervals

and appropriate action is taken with respect to any differences. Acquiring Companies’ internal controls over financial reporting

are effective and, except as set forth on Part 3.5(e) of the Company Disclosure Schedule, the Acquiring Companies are not aware

of any material weakness in their internal controls over financial reporting.

(f)

The financial statements (including any related notes) contained or incorporated by reference in the SEC Documents (the “Company

Financials”) as of the time such Company Financials were filed with the SEC (or, if amended or superseded by a filing prior

to the date hereof, then on the date of such filing): (i) complied as to form in all material respects with the published rules and regulations

of the SEC applicable thereof; (ii) where prepared in accordance with GAAP applied on a consistent basis throughout the periods involved

(except as may be indicated in the notes to such financial statements or, in the case of unaudited financial statements, as permitted

by the SEC, and except that the unaudited financial statements may not contain footnotes and are subject to normal and recurring year-end

adjustments which will not be material, either individually or in the aggregate) applied on a consistent basis unless otherwise noted

therein throughout the periods indicated; and (iii) present fairly, in all material respects, the consolidated financial position of the

Acquiring Companies as of the dates indicated and the consolidated results of operations, cash flows and changes in stockholders’

equity of the Acquiring Companies for the periods specified (subject, in the case of unaudited statements, to normal year-end audit adjustments

which are not reasonably expected to be material, either individually or in the aggregate) and have been prepared in all material respects

in compliance with the published requirements of the Securities Act and Exchange Act, as applicable and as in effect at the time of filing,

and in conformity with GAAP as in effect at the time of filing applied on a consistent basis (except (A) for such adjustments to accounting

standards and practices as are noted therein and (B) in the case of unaudited interim statements, to the extent they may exclude footnotes

or may be condensed or summary statements) during the periods involved. The unaudited balance sheet of Company as of June 30, 2026 is

hereinafter referred to as the “Company Balance Sheet.” The Company Financials will, when delivered for inclusion

in the Proxy Statement and Registration Statement for filing with the SEC following the date of this Agreement, comply as to form in all

material respects with the published rules and regulations of the SEC applicable thereto, in effect as of the dates thereof.

(g)

Since January 1, 2024, there have been no formal investigations regarding financial reporting or accounting policies initiated

at the direction of the chief executive officer, chief financial officer or general counsel of Company, the board of directors of Company

or any committee thereof.

(h)

Since January 1, 2024, neither Company nor its independent auditors have identified (i) any significant deficiency or material

weakness in the system of internal accounting controls utilized by the Company, (ii) any fraud, whether or not material, that involves

Company’s management or other employees who have a role in the preparation of financial statements or the internal accounting controls

utilized by Company or (iii) any material claim or material allegation reflecting any of the foregoing.

(i)

Acquiring Companies do not have any material liabilities or obligations, direct or contingent (including any off-balance sheet

obligations), not described in the Company Financials which are required to be described in the Company Financials.

(j)

All disclosures contained or incorporated by reference in the Company Financials, if any, regarding “non-GAAP financial measures”

(as such term is defined by the rules and regulations of the SEC) comply in all material respects with Regulation G of the Exchange Act

and Item 10 of Regulation S-K under the Securities Act, to the extent applicable.

3.6

Absence of Certain Changes or Events. Except as set forth on Part 3.6 of the Company Disclosure Schedule or as

disclosed in the SEC Documents, from the date of the Company Balance Sheet through the date hereof, each of the Acquiring Companies has

conducted its business in all material respects in the ordinary course of business consistent with past practice and there has not been

(a) any event that has had a Company Material Adverse Effect or (b) any action, event or occurrence that would have required the consent

of Santersus pursuant to Section 5.1 had such action, event or occurrence taken place after the execution and delivery of this

Agreement.

3.7

Taxes. Each of the representations and warranties set forth in this Section 3.7 is qualified by “except

as would not, individually or in the aggregate, have a Company Material Adverse Effect.”

(a)

Each income Tax Return and each other material Tax Return that were required to be filed by or with respect to any Acquiring Company

has been timely filed (taking into account all valid extensions), and all such Tax Returns were true, complete and accurate in all respects.

All Taxes due and payable by the Acquiring Companies (whether or not shown on any Tax Return) have been timely paid, except to the extent

such amounts are being contested in good faith and are properly reserved for on the books or records of the Acquiring Companies to the

extent any such reserve is required under GAAP.

(b)

No waiver or agreement by or with respect to an Acquiring Company is in force for the extension of time for the payment, collection

or assessment of any Taxes, and no request has been made by an Acquiring Company in writing for any such extension or waiver.

(c)

There are no liens for Taxes on any asset of an Acquiring Company other than liens for Taxes not yet due and payable or Taxes contested

in good faith and reserved against in accordance with GAAP.

(d)

No Acquiring Company is the subject of any currently ongoing Tax audit or other proceeding with respect to Taxes nor has any audit

or other proceeding with respect to Taxes been proposed against any of them in writing, and any deficiencies asserted or assessments made

as a result of any audit or other proceeding with respect to Taxes have been paid in full or adequate accruals or reserves for any such

deficiencies or assessments have been established and are reflected on Part 3.7(d) of the Company Disclosure Schedule and in the

Company Financials.

(e)

All material Taxes that an Acquiring Company has been required to collect or withhold have been duly collected or withheld and,

to the extent required by applicable Legal Requirements when due, have been duly and timely paid to the proper Governmental Body.

(f)

No closing agreements, private letter rulings, technical advice memoranda or similar agreements or rulings have been entered into

by any Acquiring Company with any taxing authority or issued by any taxing authority to an Acquiring Company. There are no outstanding

rulings of, or request for rulings with, any Governmental Body addressed to an Acquiring Company that are, or if issued would be, binding

on an Acquiring Company.

(g)

No Acquiring Company is a party to any Contract with any Person (other than one or more Acquiring Companies) relating to allocating

or sharing the payment of, or Liability for, Taxes or Tax benefits (other than pursuant to customary provisions included in agreements

not primarily related to Taxes and entered into in the ordinary course of business). No Acquiring Company has any Liability for the Taxes

of any Person (other than one or more Acquiring Companies) as a transferee or successor or otherwise by operation of Legal Requirements.

(h)

Within the past two (2) years, no Acquiring Company has been a member of an affiliated group of corporations within the meaning

of Section 1504 of the Code or of any group that has filed a combined, consolidated or unitary Tax Return under state, local or foreign

Tax Legal Requirement (other than a group the common parent of which was Company).

(i)

No Acquiring Company has participated in, or is currently participating in, a “listed transaction” within the meaning

of Treasury Regulation Section 1.6011-4(b)(2).

(j)

Within the past two (2) years, no Acquiring Company has distributed stock of another Person, or has had its stock distributed by

another Person, in a transaction that was purported or intended to be governed in whole or in part by Sections 355 or 361 of the Code.

(k)

No Acquiring Company has been a United States real property holding corporation within the meaning of Section 897(c)(2) of the

Code during the applicable period specified in Section 897(c)(1)(A)(ii).

(l)

No Acquiring Company is, or ever has been, a “controlled foreign corporation,” as such term is defined in Section 957

of the Code.

(m)

No Acquiring Company is aware of the existence of any fact, or has taken or agreed to take any action, that could reasonably be

expected to prevent the Acquisition from qualifying as a “reorganization” within the meaning of Section 368(a) of the Code.

3.8

Intellectual Property.

(a)

All Company IP Rights are:

(i)

legally and beneficially owned by the Acquiring Companies or lawfully used in accordance with a license agreement (which is in

full force and effect without default or breach by any party thereto);

(ii)

valid and, to the Company’s knowledge, not being infringed or challenged or opposed by any Person and no claims with regard

to these rights have been made; and

(iii)

not subject to any Encumbrance or any license in favor of another Person.

The Acquiring Companies have

fully paid all registration fees for the Company IP Rights and none of the Company IP Rights are subject to (existing or proposed) Encumbrance.

Each Acquiring Company has taken precautions and measures to protect and maintain the confidentiality of their respective trade secrets

and know-how.

(b)

To the knowledge of the Company, the Acquiring Companies own, possess, have developed, or have acquired on commercially reasonable

terms, legal rights to the Company IP Rights sufficient to carry out their respective business as now conducted.

(c)

No past or current product or service or activity of any Acquiring Company has infringed or violated or infringes or otherwise

violates any IP Rights of a third Person; provided that the foregoing representation is made to the Company’s knowledge.

(d)

To the knowledge of the Company, by conducting any Acquiring Company’s business as currently conducted or as presently proposed,

the Acquiring Companies would not infringe or violate any of the IP Rights of a third Person. No Acquiring Company has received any unsolicited

offers to license any IP Rights from any Person.

(e)

To the knowledge of the Company, no Person is presently infringing any Company IP Rights in a way that is expected to have a Company

Material Adverse Effect.

(f)

Other than pursuant to: (i) standard end-user license or services agreements for the Acquiring Companies’ products and services

on substantially the Acquiring Companies’ standard forms made available to Company, (ii) customary nondisclosure agreements entered

into by any Acquiring Company in the ordinary course of business (that do not include any terms (w) granting the right to use residuals,

(x) assigning IP Rights, (y) granting express license rights, or (z) constituting a covenant not to assert IP Rights); (iii) nonexclusive

feedback licenses and nonexclusive licenses to use trademarks, in each case that are incidental to the subject matter of the applicable

agreement in which they are incorporated; and (iv) Standard Outbound Agreements, the Acquiring Companies have not granted to any Person

any options, licenses, covenants not to assert, agreements, claims, encumbrances or shared ownership interests of any kind relating to

the Company IP Rights that are material to the Acquiring Companies’ business as now conducted.

(g)

Other than pursuant to: (i) standard license or services agreements for commercially available software products and cloud services

non-exclusively licensed to an Acquiring Company under standard terms; (ii) backup licenses from employees and contractors granted in

connection with providing services to an Acquiring Company; (iii) licenses to Open Source Software, (iv) customary nondisclosure agreements

entered into by any Acquiring Company in the ordinary course of business that do not include any terms (w) granting the right to use residuals,

(x) assigning IP Rights, (y) granting express license rights, or (z) constituting a covenant not to assert IP Rights; (v) nonexclusive

feedback licenses and nonexclusive licenses to use trademarks, in each case that are incidental to the subject matter of the applicable

agreement in which they are incorporated; and (vi) Standard Inbound Agreements, no Acquiring Company is bound by or a party to any options,

licenses, covenants not to assert or other grants or agreements of any kind with respect to IP Rights of any Person that are material

to the Acquiring Companies’ business as now conducted.

(h)

Each Acquiring Company has taken commercially reasonable measures to maintain and protect all confidential information and trade

secrets of such Acquiring Company that such Acquiring Company intended to maintain as a confidential or a trade secret. To the Company’s

knowledge, there has been no unlawful, accidental or unauthorized access to or use or disclosure of any confidential information and trade

secrets of any Acquiring Company that such Acquiring Company intended to maintain as confidential or a trade secret.

(i)

(i) Each current and former employee of an Acquiring Company has assigned to such Acquiring Company all IP Rights that such employee

has solely or jointly conceived, reduced to practice, developed, or made during the period of employment with such Acquiring Company that:

(A) relate, at the time of conception, reduction to practice, development, or making of such IP Right, to such Acquiring Company’s

business as then conducted or as then proposed to be conducted; (B) were developed on any amount of such Acquiring Company’s time

or with the use of any of such Acquiring Company’s equipment, supplies, facilities or information; or (C) resulted from such individual’s

performance of services for such Acquiring Company; (ii) each current and former consultant of any Acquiring Company who was involved

in the development of any material IP Rights for an Acquiring Company or that are otherwise owned or purported to be owned by a Acquiring

Company has assigned to such Acquiring Company all IP Rights that such consultant has solely or jointly conceived, reduced to practice,

developed, or made during the period of its consulting relationship with such Acquiring Company that resulted from such consultant’s

performance of services for such Acquiring Company; (iii) each such employee and consultant has executed an agreement with the applicable

Acquiring Company Confidential Information Agreements; (iv) no such employee or consultant has excluded IP Rights from the assignment

of IP Rights pursuant to such Person’s Confidential Information Agreement, which excluded IP Rights would be material to an Acquiring

Company in the conduct of such Acquiring Company’s business as now conducted or currently proposed to be conducted; and (v) to the

knowledge of the Company, no current or former employee or consultant is in violation of any Confidential Information Agreement.

(j)

Part 3.8(j)(i) of the Company Disclosure Schedule lists all of the Patent Rights, Trademark Rights (including domain name

registrations) and registered Copyrights owned solely by or registered solely to any Acquiring Company as of the date hereof, setting

forth in each case, as applicable, the jurisdictions in which patents have been issued, patent applications have been filed, trademarks

have been registered and trademark applications have been filed, along with the respective application, registration or filing number

thereof. Part 3.8(j)(ii) of the Company Disclosure Schedule lists, as of the date hereof, all of the Patent Rights, Trademark Rights

(including domain name registrations) and registered Copyrights in which any Acquiring Company has any co-ownership interest, other than

those owned solely by a Acquiring Company, setting forth in each case, as applicable, the jurisdictions in which patents have been issued,

patent applications have been filed, trademarks have been registered, trademark applications have been filed and registered copyrights

and copyright applications have been filed, along with the respective application, registration or filing number thereof. Part 3.8(j)(iii)

of the Company Disclosure Schedule lists all of the third party Patent Rights, Trademark Rights (including domain name registrations)

and registered Copyrights in which an Acquiring Company has any exclusive right, title or interest, other than those owned solely or co-owned

by an Acquiring Company and identified in Part 3.8(j)(i) or 3.8(j)(ii) of the Company Disclosure Schedule.

(k)

No Acquiring Company has embedded, used, linked or distributed any Open Source Software in connection with any of its products

or services or proprietary materials in any manner that requires, or purports to require, (i) any material software code owned or authored

by or on behalf of an Acquiring Company (“Company Code”) to be disclosed or distributed in source code form

or be licensed for the purpose of making derivative works; (ii) any restriction on the consideration to be charged for the distribution

of any such Company Code; (iii) the grant to any third Person of any rights or immunities under material Company Owned IP Rights; or (iv)

any other material limitation, restriction or condition on the right of any Acquiring Company with respect to its use or distribution

of any material Company Owned IP Rights (other than attribution, warranty and liability disclaimer, and notice delivery conditions). Each

Acquiring Company is in material compliance with all licenses for Open Source Software that it embeds, links to, uses or distributes.

(l)

No government funding, facilities of a university, college, hospital, foundation, other educational institution or research center,

or other funding from third Persons provided specifically for research and development was used in the development of any Company Owned

IP Rights in a manner that has resulted in such entity retaining any claim of ownership or right to use any such Company Owned IP Rights.

To the Company’s knowledge, no Person who was involved in, or who contributed to, the creation or development of any Company Owned

IP Rights, has performed services for the government, university, college, hospital, foundation, or other educational institution or research

center in a manner that would affect any Acquiring Company’s rights in the Company Owned IP Rights.

3.9

Data Privacy.

(a)

In connection with the collection, storage, use, access, disclosure and/or other processing Personal Data, by or on behalf of any

Acquiring Company, to Company’s knowledge, each Acquiring Company is and has been in compliance in all material respects with the

following: (i) all applicable Legal Requirements governing privacy or data security in all relevant jurisdictions relating to data loss,

data theft, and security breach notification obligations, telephone or text message communications, artificial intelligence and automated

decision-making, or marketing by email or other channels; (ii) such Acquiring Company’s published privacy policies; and (iii) the

privacy or data security requirements of any contracts, codes of conduct, or industry standards by which such Acquiring Company is legally

bound.

(b)

Each Acquiring Company maintains and has maintained reasonable physical, technical, and administrative security measures and policies

designed to protect all Personal Data and confidential or proprietary data owned, stored, used, maintained or controlled by or on behalf

of such Acquiring Company from and against unlawful, accidental or unauthorized access, destruction, loss, use, modification, disclosure,

and/or other processing.

(c)

There has been no material security breach, unauthorized access, use, disclosure, modification, destruction or other incident or

compromise of or relating to any of the Acquiring Companies’ information technology and computer systems, networks, hardware, software,

data (including all Personal Data and the data of their respective customers, employees, suppliers, vendors and any third party data maintained

by or on behalf of them), equipment or technology (collectively, “Company IT Systems and Data”) and, to Company’s

knowledge, no event or condition exists as of the date of this Agreement that would reasonably be expected to result in, any such material

security breach, unauthorized access, use, disclosure, modification, destruction or other compromise of Company IT Systems and Data. The

Acquiring Companies employ commercially reasonable physical, technical, and administrative security measures, controls, safeguards, policies

and procedures designed to (i) protect all Company IT Systems and Data from and against material unauthorized access, use and/or disclosure

and (ii) maintain the integrity, continuous operation, redundancy and security of the Company IT Systems and Data. The Acquiring Companies

are presently, and since January 1, 2023 have been, in compliance in all material respects with all applicable Legal Requirements governing

the data privacy and security of Personal Data, and all judgments, orders, rules, directives and decrees of any court or arbitrator or

governmental or regulatory authority, company policies and contractual obligations relating to the privacy and security of Company IT

Systems and Data and to the protection of such Company IT Systems and Data from unauthorized use, access, misappropriation or modification,

except as would not, individually or in the aggregate, have a Company Material Adverse Effect, and the Acquiring Companies have implemented

backup and disaster recovery technology consistent with industry standards and practices.

(d)

No Person (including any Governmental Body) has asserted a claim, or otherwise threatened in writing to commence any action, against

any Acquiring Company alleging a violation of any privacy policy of the Acquiring Companies or any applicable Legal Requirements pertaining

to privacy and data protection. No Acquiring Company has received any written inquiry or complaint from any Governmental Body regarding

the collection, use, retention, storage, security, transfer, disposal, disclosure or other processing of Personal Data or confidential

or proprietary data by or for the Acquiring Companies.

3.10

Compliance with Legal Requirements.

(a)

Since January 1, 2023, each Acquiring Company has conducted and, as of the date hereof, continues to conduct its business in compliance

in all respects with all applicable Legal Requirements and Orders, except for such violations that would not, individually or in the aggregate,

reasonably be expected to have a Company Material Adverse Effect.

(b)

Since January 1, 2023, no investigation or inquiry is pending or threatened in writing and no Order has been issued by any Governmental

Body or self-regulatory body regarding any matter against any Acquiring Company or, to the knowledge of the Company, any Person for whose

acts or omissions an Acquiring Company may be liable in connection with the breach or alleged breach of any Legal Requirements. No Acquiring

Company is under any obligation to remedy any unlawful situation in respect of any of its assets or activities, in each case, that would

be material to the Acquiring Companies, taken as a whole.

(c)

Each Acquiring Company has all franchises, permits, licenses and any similar authority necessary for the conduct of its business

(the “Company Permits”), the lack of which would reasonably be expected to have a Company Material Adverse Effect.

No Acquiring Company is in default in any material respect under any of such franchises, permits, licenses or other similar authority,

except for any such default as would reasonably be expected to have a Company Material Adverse Effect. No action, proceeding, revocation

proceeding, amendment procedure, writ, injunction or claim is pending or, to the knowledge of Company, threatened in writing, which seeks

to revoke or limit any Company Permit that would be material to the Acquiring Companies, taken as a whole. Company has made available

to Santersus all material Company Permits.

(d)

Since January 1, 2023, no Acquiring Company, nor any director, officer, or, to the knowledge of the Company, any employee or agent

of the Acquiring Companies has taken any action, directly or indirectly, (i) in furtherance of a corrupt offer, payment, promise to pay,

or authorization or approval of the payment, giving or receipt of money, property, gifts or anything else of value, to any government

official (including any officer or employee of a government or government-owned or controlled entity or of a public international organization,

or any person acting in an official capacity for or on behalf of any of the foregoing or any political party or party official or candidate

for political office) in order to influence official action or secure an unlawful business advantage, or (ii) in violation of the Anti-Corruption

Laws, except in the case of (i) and (ii) as would not, individually or in the aggregate, reasonably be expected to have a Company Material

Adverse Effect. The Acquiring Companies have instituted and maintained policies and procedures reasonably designed to promote and achieve

compliance with Anti-Corruption Laws. No part of the proceeds of the offering will be used by the Acquiring Companies, or their Affiliates,

directly or, to the knowledge of the Company, indirectly, in violation of the Anti-Corruption Laws.

(e)

The operations of the Acquiring Companies are and, since January 1, 2023, have been conducted at all times in material compliance

with applicable financial recordkeeping and reporting requirements, including, to the extent applicable, those of the Bank Secrecy Act,

as amended by Title III of the Uniting and Strengthening America by Providing Appropriate Tools Required to Intercept and Obstruct Terrorism

Act of 2001 (USA PATRIOT Act), and the anti-money laundering statutes and the rules and regulations thereunder and any related or similar

rules, regulations or guidelines, issued, administered or enforced by any governmental agency (collectively, the “Anti-Money

Laundering Laws”) and no action, suit or proceeding by or before any court or governmental agency, authority or body or

any arbitrator involving the Acquiring Companies with respect to the Anti-Money Laundering Laws is pending or, to the knowledge of the

Company, threatened.

(f)

To the Company’s knowledge, since January 1, 2023, each Acquiring Company has been in material compliance with all applicable

Legal Requirements administered or enforced by the FDA or any similar Governmental Body regarding developing, testing, manufacturing,

marketing, distributing or promoting the products of such Acquiring Company.

(g)

At no time since January 1, 2024 has any of the Acquiring Companies received written notice that any Governmental Body or institutional

review board has commenced, or threatened to initiate, any proceeding seeking the suspension or termination of nonclinical research with

respect to any product candidate being researched or developed by or on behalf of any of the Acquiring Companies. Neither any Acquiring

Companies nor, to the Company’s knowledge, any officer, employee or agent of any Acquiring Companies has been convicted of any crime

or engaged in any conduct that has previously caused or would reasonably be expected to result in (A) disqualification or debarment by

the FDA under 21 U.S.C. Sections 335(a) or (b), or any similar law, rule or regulation of any other Governmental Body, (B) debarment,

suspension, or exclusion by the General Services Administration or any other Governmental Body, or (C) exclusion under 42 U.S.C. Section

1320a-7 or any similar law, rule or regulation of any Governmental Body. None of the Acquiring Companies and, to the Company’s knowledge,

no Representative of any Acquiring Company or Person acting in concert with or on behalf of the Acquiring Companies, or any officers,

employees or Representatives of the same, has with respect to any product that is manufactured, tested, distributed, or held by or on

behalf of any of the Acquiring Companies made an untrue statement of a material fact or fraudulent statement to the FDA or any other Governmental

Body, failed to disclose a material fact required to be disclosed to the FDA or any other Governmental Body, or committed an act, made

a statement, or failed to make a statement that, at the time such disclosure was made, would reasonably be expected to provide a basis

for invocation of a relevant FDA Application Integrity Policy. Neither the Acquiring Companies nor any officers, employees, or to the

Company’s knowledge, any contractors or agents is the subject of any pending or threatened (in writing) investigation by FDA pursuant

to the FDA Application Integrity Policy or by any other Governmental Body pursuant to any similar policy. To the Company’s knowledge,

neither the Acquiring Companies nor any officers, employees, contractors, and agents has committed any act, made any statement or failed

to make any statement that would reasonably be expected to provide a basis for FDA to invoke the FDA Application Integrity Policy or for

any other Governmental Body to invoke a similar policy. Neither the Acquiring Companies nor any officers, employees, or to the Company’s

knowledge, any contractors or agents has made any materially false statements on, or material omissions from, any notifications, applications,

reports and other submissions to FDA or any other Governmental Body.

(h)

To the Company’s knowledge, the Acquiring Companies and Persons acting in concert with and on behalf of the Company have

not used in any capacity the services of any individual or Entity debarred, excluded, or disqualified under 21 U.S.C. Section 335a, 42

U.S.C. Section 1320a-7 or 21 C.F.R. Section 312.70, or any similar Legal Requirements in any jurisdiction.

(i)

All nonclinical and clinical studies relating to product candidates conducted by or on behalf of the Acquiring Companies have been,

or are being, conducted in all material respects in compliance with the applicable requirements of the FDA’s Good Laboratory Practice

and Good Clinical Practice requirements, including regulations codified at 21 C.F.R. Parts 50, 54, 56, 58, and 312, as amended from time

to time, and all applicable similar requirements in other jurisdictions, including all requirements relating to protection of human subjects

participating in any such clinical studies; provided, however, that the foregoing representation and warranty specifically

excludes nonclinical studies that were not designed to be conducted in accordance with Good Laboratory Practice. No Acquiring Company

has received any notices or correspondence from the FDA or any other Governmental Body requiring the termination, suspension or material

modification of any nonclinical study or clinical trial after initiation thereof by or on behalf of the Company.

(j)

None of the Acquiring Companies is a party to any corporate integrity agreement, monitoring agreement, consent decree, settlement

order, or similar agreement with or imposed by any Governmental Body. None of the Acquiring Companies is subject to any investigation

that is pending or, to the Company’s knowledge, that has been threatened, in each case by (i) the FDA pursuant to the Federal Food,

Drug, and Cosmetic Act (21 U.S.C. §301 et seq.) or (ii) the Department of Health and Human Services Office of Inspector General

or Department of Justice pursuant to the Federal Anti-Kickback Statute (42 U.S.C. §1320a-7b(b)) or the Federal Civil False Claims

Act (31 U.S.C. §3729), or any similar investigation that is pending or, to the Company’s knowledge, that has been threatened

by any other Governmental Body pursuant to any other applicable Legal Requirements.

(k)

None of the Acquiring Companies has received any FDA Form 483s, warning letters, untitled letters, cyber letters, notices of violation,

consent decrees, notice of investigation, indictments, sentencing memoranda, plea agreements, court orders, target or no target letters,

proceedings, review (including data integrity reviews) or other notices of enforcement actions from a Governmental Body.

(l)

The Company has, prior to the execution of this Agreement, disclosed to Santersus all material information known by the Acquiring

Companies with respect to the safety and efficacy of the Company’s product candidates.

3.11

Legal Proceedings; Orders.

(a)

As of the date of this Agreement, there is no claim, action, suit, proceeding, arbitration, complaint, charge or investigation

pending or to Company’s knowledge, currently threatened in writing: (i) against any Acquiring Company or any officer or director

of any Acquiring Company arising out of their capacity as an officer or director of such Acquiring Company; (ii) that involves any of

the Acquiring Companies, any business of any of the Acquiring Companies or any of the assets owned by any of the Acquiring Companies;

(iii) that questions the validity of this Agreement or the right of any Acquiring Company to enter into them, or to consummate the transactions

contemplated by this Agreement; or (iv) that would reasonably be expected to have, either individually or in the aggregate, a Company

Material Adverse Effect. Neither any Acquiring Company nor, to Company’s knowledge, any of its officers or directors is a party

or is named as subject to the provisions of any order, writ, injunction, judgment or decree of any Governmental Body (in the case of officers

or directors, such that arises out of their capacity as an officer or director of such Acquiring Company and as would affect any Acquiring

Company). There is no material action, suit, proceeding or investigation by any Acquiring Company pending or which any Acquiring Company

intends to initiate.

(b)

As of the date of this Agreement, there is no Order to which any of the Acquiring Companies, or any of the assets owned or used

by any of the Acquiring Companies, is subject. To the knowledge of Company, no officer or other key employee of any of the Acquiring Companies

is subject to any Order that prohibits such officer or other employee from engaging in or continuing any conduct, activity or practice

relating to the business of any of the Acquiring Companies.

(c)

No Acquiring Company is insolvent or unable to pay its debts when due.

3.12

Brokers’ and Finders’ Fees. Except as set forth on Part 3.12 of the Company Disclosure Schedule,

no broker, finder or investment banker is entitled to any brokerage, finder’s or other fee or commission in connection with the

Contemplated Transactions based upon arrangements made by or on behalf of any of the Acquiring Companies. Company has furnished to Santersus

accurate and complete copies of all agreements under which any such fees, commissions or other amounts have been paid or may become payable

and all indemnification and other agreements related to the engagement of any Persons listed on Part 3.12 of the Company Disclosure

Schedule.

3.13

Employee Benefit Plans.

(a)

Part 3.13(a) of the Disclosure Schedule sets forth, as of the date hereof, a complete and accurate list of each plan, program,

policy, Contract or other arrangement providing for employment, compensation, retirement, pension, nonqualified deferred compensation,

severance, separation, relocation, termination pay, performance awards, bonus, incentive compensation, stock option, stock purchase, stock

bonus, phantom stock, stock appreciation right, other equity-based award, supplemental retirement, profit sharing, fringe benefits, cafeteria

benefits, medical benefits, life insurance, disability benefits, accident benefits, salary continuation, reimbursements, accrued leave,

vacation, or other material employee benefits, whether written or unwritten, and each other “employee benefit plan” within

the meaning of Section 3(3) of ERISA, in each case, for current, retired or former employees, directors or consultants of the Acquiring

Companies, which is sponsored, maintained, contributed to, or required to be contributed to by any of the Acquiring Companies or with

respect to which any Acquiring Company has any material Liability either directly or through a Company ERISA Affiliate (the “Company

Employee Plans”). The Company Employee Plans set forth in Part 3.13(a) of the Disclosure Schedule include the employee benefit

plans provided by, maintained, or sponsored through a professional employer organization or co-employer organization (a “PEO,”

and each such Company Employee Plan, a “PEO Plan,” and each Company Employee Plan that is not a PEO Plan, a

“Company Plan”), The term “Company ERISA Affiliate” means any Person, trade or business,

or other entity, that at any relevant time is or was treated as a single employer with the Company or any of its Subsidiaries pursuant

to Section 414 of the Code.

(b)

The Acquiring Companies have made available to Santersus true and complete copies of each Company Plan and all material related

Company Plan documents, Form 5500s for the three most recent plan years, nondiscrimination tests for the last three plan years, and material

correspondence with the IRS, DOL, or PBGC within the last six years. With respect to each PEO Plan, the Company shall satisfy

the requirements of this Section 3.13(b) by using commercially reasonable efforts to cause the PEO to deliver to Santersus (or

to provide to the Company for delivery to Santersus) a copy of the plan documents, Form 5500s for the three most recent plan years, nondiscrimination

tests for the last three plan years, and material correspondence with the IRS, DOL, or PBGC within the last six years. Each Company Plan

and, to the knowledge of the Company, each PEO Plan has been maintained and administered in all material respects in accordance with its

terms and in material compliance with the requirements prescribed by applicable Legal Requirements (including, where applicable, ERISA

and the Code). No Company Employee Plan promises or provides retiree medical or other retiree life, disability or welfare

benefits to any person, except to the extent required by Section 4980B of the Code or any similar state or non-U.S. Legal Requirement,

the cost of which is fully paid by the participants. Each Company Plan and, to the knowledge of the Company, each PEO Plan

that is subject to Code Section 409A has been administered and operated in documentary and operational compliance with the requirements

of Section 409A of the Code an no additional tax under Section 409A(a)(1)(B) of the Code has been or could reasonably be expected to be

incurred by a participant in any such Plan.

(c)

Neither any Acquiring Company nor any Company ERISA Affiliate has ever maintained, established, sponsored, participated in or contributed

to, or is or has been obligated to contribute to, or otherwise incurred any Liability under, any “multiemployer plan” (as

defined in Section 3(37) of ERISA) or any “pension plan” (as defined in Section 3(2) and Section 3(35) of ERISA) subject to

Section 302 or Title IV of ERISA or Section 412 of the Code or any multiple employer plan under Section 413(c) of the Code, or any multiple

employer welfare arrangement within the meaning of Section 3(40) of ERISA or any voluntary employees’ beneficiary association under

Section 501(c)(9) of the Code.

(d)

Other than as specifically contemplated by this Agreement or as set forth in Part 3.13(e) of the Company Disclosure

Schedule, the consummation of the Acquisition will not, either alone or in combination with another event, (i) entitle any current or

former employee or other service provider of any Acquiring Company to severance benefits or any other payment (including golden parachute

or bonus payments); (ii) accelerate the time of payment or vesting of any such payments or benefits or increase the amount of compensation

or benefits due any such employee or service provider; (iii) result in the forgiveness of any indebtedness; or (iv) result in any obligation

to fund future benefits under any Company Plan. No benefit payable or that may become payable by an Acquiring Company in connection

with the Contemplated Transactions or as a result of or arising under this Agreement (either alone or in combination with another event)

is reasonably likely to constitute an “excess parachute payment” (as defined in Section 280G(b)(1) of the Code) subject to

the imposition of an excise Tax under Section 4999 of the Code or the deduction for which would be disallowed by reason of Section 280G

of the Code. No Acquiring Company has any gross up or indemnity obligation to any individual for taxes imposed under Code Section 409A

or 4999.

(e)

No Person has any “gross up” agreements with any Acquiring Company or other assurance of reimbursement or indemnity

by any Acquiring Company for any Taxes imposed under Section 409A or Section 4999 of the Code.

3.14

Title to Assets; Real Property. Except as set forth on Part 3.14(i) of the Company Disclosure Schedule, the Acquiring

Companies own, and have good, valid and marketable title to, all material tangible assets purported to be owned by them, including all

material tangible assets reflected in the books and records of the Acquiring Companies as being owned by the Acquiring Companies. All

of said assets are owned by the Acquiring Companies free and clear of any Encumbrances, except for Permitted Encumbrances and as set forth

on Part 3.14(ii) of the Company Disclosure Schedule. The Acquiring Companies do not own and have never owned any real property,

and do not currently hold any interest in real property, except for the leaseholds created under the real property leases identified on

Part 3.14(iii) of the Company Disclosure Schedule. The Acquiring Companies are the lessees of, and hold valid leasehold interests

in, all assets purported to have been leased by them, including all assets reflected in the books and records of the Acquiring Companies

as being leased to the Acquiring Companies, and the Acquiring Companies enjoy undisturbed possession of such leased assets. Part 3.14(iv)

of the Company Disclosure Schedule sets forth a complete and accurate list of all real property leases to which any Acquiring Company

is a party, which are each in full force and effect, and with no existing default thereunder, except as would not be reasonably expected

to have a Company Material Adverse Effect.

3.15

Environmental Matters. Each Acquiring Company is in compliance with all applicable Environmental Laws, which compliance

includes the possession by Company of all permits and other authorizations required under applicable Environmental Laws and compliance

with the terms and conditions thereof, except where the failure to be in compliance would not, individually or in the aggregate, have

a Company Material Adverse Effect. Since January 1, 2023, no Acquiring Company has received any written notice or other communication

(in writing), whether from a Governmental Body, citizens group, employee or otherwise, that alleges that any Acquiring Company is not

in compliance in all material respects with any Environmental Law, and, to the knowledge of Company, there are no circumstances existing

as of the date hereof that would prevent or interfere with any Acquiring Company’s compliance in all material respects with any

Environmental Law in the future. To the knowledge of Company: (i) no current or prior owner of any property leased or controlled by any

Acquiring Company has received any written notice or other communication (in writing) relating to property owned or leased at any time

by any Acquiring Company, whether from a Governmental Body, citizens group, employee or otherwise, that alleges that such current or prior

owner or any Acquiring Company is not in compliance in all material respects with or has violated any Environmental Law relating to such

property; and (ii) no Acquiring Company has any material liability under any Environmental Law.

3.16

Labor Matters.

(a)

Part 3.16(a) of the Company Disclosure Schedule sets forth a true, complete and correct list as of the date of this Agreement

of all employees of the Acquiring Companies along with each such employee’s position, whether classified as exempt or non-exempt

for wage and hour purposes, business location, status (i.e., active or inactive and if inactive, the type of leave and estimated duration),

hire date, actual compensation and annual rate of compensation as of the date hereof (including base salary and the target amount of any

bonuses to which such employee may be eligible) and the total amount of bonus, retention, severance and other amounts to be paid to such

employee at the Closing or otherwise in connection with the Acquisition. All employment agreements between the Acquiring Companies and

their employees are in writing and contain all terms and conditions applicable to the respective employment relationship.

(b)

There are no agreements or other arrangements between the Acquiring Companies and any trade union or other body representing employees.

(c)

The Acquiring Companies are in compliance in all material respects with all Legal Requirements relating to employment practices,

terms and conditions of employment, and the employment of former, current, and prospective employees, individual independent contractors

and “leased employees” (within the meaning of Section 414(n) of the Code in the United States and other Legal Requirements

in any jurisdiction in which the Acquiring Companies employ interim employees), including all such Legal Requirements and Contracts relating

to wages, hours, collective bargaining, classification of employees, employment discrimination, immigration, disability, civil rights,

fair labor standards, occupational safety and health, and workers’ compensation, and have timely prepared and, as applicable, filed

all employment-related forms (including United States Citizenship and Immigration Services Form I-9) to the extent required by any relevant

Governmental Body.

(d)

No Legal Proceedings are as of the date of this Agreement open and pending (or within the past three years have been settled or

otherwise closed) against any Acquiring Company with respect to the employment of, or failure to employ, any individual, including any

brought with or by the Equal Employment Opportunity Commission, the Office of Federal Contract Compliance Programs, or other applicable

Governmental Body regulating the employment or compensation of individuals (or, with respect to discrimination, unlawful harassment, retaliation,

or similar wrongdoing, pursuant to internal complaint procedures), and no Company Personnel has made, within the past three years a written

complaint of discrimination, unlawful harassment, retaliation, or other similar wrongdoing or, to the knowledge of Company, within the

past three years, an oral complaint. Within the last three years, no Acquiring Company has received any requests for, or conducted, an

internal investigation of any officer, manager, or supervisor of any Company Personnel with respect to any claims with respect to discrimination,

unlawful harassment, retaliation, or other similar wrongdoing.

(e)

Within the past three (3) years, no Acquiring Company has caused (i) a plant closing as defined in the WARN Act affecting any single

site of employment of any Acquiring Company or one or more operating units within any site of employment of any Acquiring Company or (ii)

a mass layoff as defined in the WARN Act, nor has any Acquiring Company been affected by any transaction or engaged in layoffs or employment

terminations sufficient in number to trigger application of any similar foreign, state or local Law.

(f)

Part 3.16(f) of the Company Disclosure Schedule sets forth each Person retained by any Acquiring Company as an individual

consultant or independent contractor since January 1, 2023 and further sets forth the following information with respect to each: (i)

name, (ii) services provided, (iii) date of engagement (iv) the entity or entities to which the individual provides services, (v) fees

paid or payable to the individual, and (vi) service location (including city, state, and country). No Acquiring Company retains, and has

retained in the past, any consultants or freelancers that could be requalified as employees under applicable laws under applicable Legal

Requirements.

(g)

Each current and former employee, consultant and officer of each Acquiring Company involved in the development of Company IP Rights

is or was, when being occupied to the benefit of the relevant Acquiring Company, bound by appropriate undertakings to ensure the assignment

to the relevant Acquiring Company of any IP Rights developed by such person.

3.17

Company Contracts.

(a)

Part 3.17 of the Company Disclosure Schedule lists each of the following Contracts in effect as of the date of this Agreement

to which any Acquiring Company is a party or by which any Acquiring Company is bound (each, a “Company Contract”):

(i)

any Contract incorporating or relating to any warranty, any sharing of Liabilities or any indemnity not entered into in the ordinary

course of business, including any indemnification agreements between an Acquiring Company and any of its officers or directors;

(ii)

any Contract imposing any material restriction on the right or ability of any Acquiring Company: (A) to compete with any other

Person; (B) to acquire any product or other asset or any services from any other Person; (C) to develop, sell, supply, distribute, offer,

support or service any product or any technology or other asset to or for any other Person; (D) to perform services for any other Person;

or (E) to otherwise transact business with any other Person;

(iii)

any Contract containing “most favored” provisions, board of directors observer rights, or other side letter agreements

not otherwise disclosed pursuant to any other representation;

(iv)

any Contract relating to the acquisition of any material interest in, or any material amount of, property or assets of any Acquiring

Company, other than in the ordinary course of business, or any ownership interest in any corporation, partnership, joint venture or other

business enterprise;

(v)

any joint marketing or collaboration Contract;

(vi)

any Contract containing obligations (contingent or otherwise) of, or payments to, any Acquiring Company in excess of $125,000 (other

than employment agreements and offer letters or other engagements with individual service providers);

(vii)

any Contract that provides for: (A) any right of first refusal, right of first negotiation, right of first notification or similar

right with respect to any securities or assets of any Acquiring Company; or (B) any “no shop” provision or similar exclusivity

provision with respect to any securities or assets of any Acquiring Company;

(viii)

any Contract containing the grant of rights to manufacture, produce, assemble, license, market, or sell its products to any other

Person that limits any Acquiring Company’s exclusive right to develop, manufacture, assemble, distribute, market or sell such Acquiring

Company’s products;

(ix)

any Contract for university licenses;

(x)

any Contract providing any severance or change-in-control payment or benefit to any officer, director or employee of any Acquiring

Company;

(xi)

any Contract with any Governmental Body that is material to the business or operations of the Acquiring Companies;

(xii)

any Contract (other than any employment agreement, offer letter or similar agreement) with any officer or directors of the Company

or any “beneficial owner” (as such term is defined in Rule 13d-3 under the Exchange Act of 5% or more of the outstanding shares

of any class of voting securities of the Company);

(xiii)

any Contract containing any royalty, dividend or similar arrangement based on the revenues or profits of any Acquiring Company;

(xiv)

any Contract for leased real property;

(xv)

any Contract with any financial advisor, broker, finder, investment bank or other Person, providing advisory services;

(xvi)

any Contract that is not terminable by the Company with no more than ninety (90) days prior notice to the other party (with no

penalty or payment) by Company and (A) which involves payment or receipt by any Acquiring Company after the date of this Agreement under

any such Contract of more than $125,000 in the aggregate, or obligations after the date of this Agreement in excess of $125,000 in the

aggregate or (B) that is material to the business or operations of the Acquiring Companies;

(xvii)

any Contract not entered into in the ordinary course of business that contemplates or involves the payment or delivery of cash

or other consideration in an amount or having a value in excess of $125,000 in the aggregate, or contemplates or involves the performance

of services having a value in excess of $125,000 in the aggregate, other than any arrangement or agreement expressly contemplated by or

provided for under this Agreement; or

(xviii) any

Contract required to be filed by Company as a “material contract” pursuant to Item 601(b)(10) of Regulation S-K under

the Securities Act; or

(b)

Company has made available to Santersus an accurate and complete copy of each Company Contract. There are no Company Contracts

that are not in written form. No Acquiring Company and, to Company’s knowledge, no other party to a Company Contract has breached

or violated in any material respect or materially defaulted under, or received written notice that it has breached, violated or defaulted,

in any material respects, under, any of the terms or conditions of any of the Company Contracts. To the knowledge of Company, no event

has occurred, and no circumstance or condition exists, that (with or without notice or lapse of time or both) would reasonably be expected

to: (i) result in a violation or breach in any material respect of any of the provisions of any Company Contract; (ii) give any Person

the right to declare a default in any material respect under any Company Contract; (iii) give any Person the right to receive or require

a rebate, chargeback, penalty or change in delivery schedule under any Company Contract; (iv) give any Person the right to accelerate

the maturity or performance of any Company Contract; or (v) give any Person the right to cancel, terminate or modify any Company Contract.

Except as set forth on Part 3.17 of the Company Disclosure Schedule, the consummation of the Acquisition will not (either alone

or upon the occurrence of additional acts or events) result in any material payment or payments becoming due from any Acquiring Company

to any Person under any Company Contract or give any Person the right to terminate or alter the provisions of any Company Contract. No

Person is renegotiating any material amount paid or payable to any Acquiring Company under any Company Contract or any other material

term or provision of any Company Contract. Each Company Contract is valid, binding, enforceable and in full force and effect, except as

enforceability may be limited by bankruptcy and other similar laws and general principles of equity.

3.18

Insurance.

(a)

Each of the Acquiring Companies’ Insurance Policies are in full force and effect on the date hereof and are maintained with

reputable companies against loss relating to the business, operations and properties and such other risks as companies engaged in similar

business as the Acquiring Companies would, in accordance with good business practice, customarily insure. All premiums due and payable

under such Insurance Policies have been paid on a timely basis and each Acquiring Company is in compliance in all material respects with

all other terms thereof. True, complete and correct copies of such Insurance Policies have been made available to Santersus.

(b)

Except as set forth on Part 3.18(b) of the Company Disclosure Schedule, there are no material claims pending, under any

Insurance Policy to which any Acquiring Company is a party, as to which coverage has been questioned, denied or disputed. All material

claims thereunder have been filed in a due and timely fashion in all material respects and since January 1, 2023 no Acquiring Company

has been refused insurance for which it has applied or had any policy of insurance terminated (other than at its request), nor has any

Acquiring Company received written notice from any insurance carrier that: (i) such insurance will be canceled or that coverage thereunder

will be materially reduced or eliminated; or (ii) premium costs with respect to such insurance will be materially increased, other than

premium increases in the ordinary course of business applicable on their terms to all holders of similar policies.

3.19

Code of Ethics. Company has adopted a code of ethics, as defined by Item 406(b) of Regulation S-K of the SEC, for senior

financial officers, applicable to its principal executive officer, principal financial officer, controller or principal accounting officer,

or persons performing similar functions. Company has promptly disclosed any change in or waiver of Company’s code of ethics with

respect to any such persons, as required by Section 406(b) of the Sarbanes-Oxley Act. To the knowledge of Company, there have been no

material violations of provisions of Company’s code of ethics by any such persons.

3.20

Opinion of Financial Advisor. The Special Committee of Company has received an opinion of Canaccord Genuity LLC, financial

advisor to Company, dated September 14, 2026, to the effect that the Acquisition Consideration is fair to the Company Stockholders from

a financial point of view. Company will furnish an accurate and complete copy of said opinion to Santersus and Sellers for informational

purposes only promptly after the date hereof.

3.21

Interested Party Transactions. Except as set forth on Part 3.21 of the Company Disclosure Schedule or disclosed

in the SEC Documents, no event has occurred since January 1, 2023 that would be required to be reported by any Acquiring Company as a

“Certain Relationship” or “Related Transaction” pursuant to Item 404 of Regulation S-K pursuant to the Exchange

Act.

3.22

Valid Issuance. The Company Common Stock to be issued in the Acquisition will, when issued in accordance with the provisions

of this Agreement, be validly issued, fully paid and nonassessable.

3.23

No TID U.S. Business. None of the Acquiring Companies are a U.S. business that engages in (i) the production, design,

testing, manufacture, fabrication, or development of one or more “critical technologies” within the meaning of the Defense

Production Act of 1950, as amended, including all implementing regulations thereof (the “DPA”); (ii) the ownership,

operation, maintenance, supply, manufacture, or servicing of “covered investment critical infrastructure” within the meaning

of the DPA (where such activities are covered by column 2 of Appendix A to 31 C.F.R. Part 800); or (iii) the maintenance or collection,

directly or indirectly, of “sensitive personal data” of U.S. citizens within the meaning of the DPA.

3.24

Disclosure; Company Information. None of the information supplied or to be supplied by or on behalf of Company for inclusion

or incorporation by reference in the Proxy Statement or Registration Statement will, at the time the Proxy Statement or Registration Statement,

as applicable, is filed with the SEC, at any time it is amended or supplemented, or at the time it becomes effective under the Securities

Act, contain any statement that, in light of the circumstances under which it was made, is false or misleading with respect to any material

fact or omit to state any material fact necessary in order to correct any statement of a material fact in any earlier communication with

respect to the solicitation of proxies for the Company Stockholders’ Meeting which has become false or misleading. None of the information

supplied or to be supplied by or on behalf of Company for inclusion or incorporation by reference in the Proxy Statement will, at the

time the Proxy Statement is first mailed to the Company Stockholders or at the time of the Company Stockholders’ Meeting, contain

any statement that, in light of the circumstances under which it was made, is false or misleading with respect to any material fact or

omit to state any material fact necessary in order to correct any statement of a material fact in any earlier communication with respect

to the solicitation of proxies for the Company Stockholders’ Meeting which has become false or misleading. The Proxy Statement and

Registration Statement will comply as to form in all material respects with the applicable Legal Requirements. Notwithstanding the foregoing,

no representation is made by Company with respect to the information that has been or will be supplied by any of the Santersus Companies,

any Seller or any of their respective Representatives for inclusion in the Proxy Statement.

3.25

Exclusivity of Representations; Reliance.

(a)

Except as expressly set forth in this Article 3, neither Company nor any Person on behalf of Company has made, nor are any

of them making, any representation or warranty, written or oral, express or implied, at law or in equity, including with respect to merchantability

or fitness for any particular purpose, in respect of Company or its business in connection with the Contemplated Transactions, including

any representations or warranties about the accuracy or completeness of any information or documents previously provided (including with

respect to any financial or other projections therein), and any other such representations and warranties are hereby expressly disclaimed.

(b)

Company acknowledges and agrees that, except for the representations and warranties of Santersus set forth in Article 2

and Sellers set forth in Article 4, neither Company nor its Representatives is relying on any other representation or warranty

of Santersus, Sellers, or any other Person made outside of Article 2 and Article 4, including regarding the accuracy or

completeness of any such other representations or warranties or the omission of any material information, whether express or implied,

in each case with respect to the Acquisition.

Article

REPRESENTATIONS AND WARRANTIES OF SELLERS

Each Seller, severally and

not jointly, represents and warrants to Santersus and Company as to itself as follows:

4.1

Ownership of Santersus Share Capital. Such Seller is the sole record, legal and beneficial owner of, as of the date

hereof, all of the shares of Santersus Issued Share Capital listed next to the name of such Seller on Part 2.2(b) of the Santersus

Disclosure Schedule. As of the Closing, such Seller will be the sole record, legal and beneficial owner of all of the Santersus Shares

listed next to the name of such Seller on Part 2.2(b) of the Santersus Disclosure Schedule. Except as set forth on Part 2.2(b)

of the Santersus Disclosure Schedule, such Seller is not a party to any option, warrant, purchase right or other Contract that could require

such Seller to sell, transfer or otherwise dispose of any of its shares of Santersus Share Capital (other than as set forth in this Agreement)

and has good and valid title to all of the shares of Santersus Share Capital held by such Seller and will, as of the Closing, have good

and valid title to all Santersus Shares issuable in respect of such shares of Santersus Share Capital, in each case free and clear of

all Encumbrances (except as are imposed by federal and state securities laws). Subject only to stamping, upon the consummation of the

Acquisition, Company will acquire good and marketable title to the Santersus Shares acquired by Company from such Seller, free and clear

of all Encumbrances (except as are imposed by federal and state securities laws).

4.2

Authority; Non-Contravention.

(a)

If a natural person, such Seller has the requisite legal capacity to enter into this Agreement, to perform its obligations hereunder

and to consummate the Contemplated Transactions. If not a natural person, (i) such Seller has the requisite corporate, limited liability

company or similar power and authority to enter into this Agreement, to perform its obligations hereunder and to consummate the Contemplated

Transactions and (ii) the execution and delivery of this Agreement by such Seller, the performance by such Seller of its obligations hereunder

and the consummation by such Seller of the Contemplated Transactions have been duly authorized by all necessary corporate action on the

part of such Seller. This Agreement has been duly executed and delivered by such Seller and, assuming the due authorization, execution

and delivery by Santersus and Company, constitutes the valid and binding obligation of such Seller, enforceable in accordance with its

terms, subject to applicable bankruptcy, insolvency, fraudulent transfer, reorganization, moratorium and other laws affecting creditors’

rights generally and general principles of equity.

(b)

The execution and delivery of this Agreement by such Seller does not, and the performance of this Agreement by such Seller will

not, conflict with or violate any Organizational Document or Legal Requirement applicable to such Seller or by which its properties are

bound or affected.

(c)

Such Seller is not subject to any Insolvency Proceedings.

4.3

Tax Matters. Such Seller has had the opportunity to review with such Seller’s tax advisors the applicable Tax

consequences of the Contemplated Transactions, including the purchase of the Santersus Shares acquired from such Seller by Company. Such

Seller is relying solely on such advisors and not on any statements or representations of Company or Santersus or any of their respective

Representatives with respect to Tax matters. Such Seller understands that it (and not Company or Santersus) shall be responsible for such

Seller’s Tax Liability and any related interest and penalties that may arise as a result of the Contemplated Transactions.

4.4

Disclosure; Seller Information. None of the information supplied or to be supplied by or on behalf of such Seller in

writing for inclusion or incorporation by reference in the Proxy Statement or Registration Statement will, at the time the Proxy Statement

or Registration Statement, as applicable, is filed with the SEC, at any time it is amended or supplemented, or at the time it becomes

effective under the Securities Act, contain any statement that, in light of the circumstances under which it was made, is false or misleading

with respect to any material fact or omit to state any material fact necessary in order to correct any statement of a material fact in

any earlier communication with respect to the solicitation of proxies for the Company Stockholders’ Meeting which has become false

or misleading. None of the information supplied or to be supplied by or on behalf of such Seller in writing for inclusion or incorporation

by reference in the Proxy Statement will, at the time the Proxy Statement is first mailed to the Company Stockholders or at the time of

the Company Stockholders’ Meeting, contain any statement that, in light of the circumstances under which it was made, is false or

misleading with respect to any material fact or omit to state any material fact necessary in order to correct any statement of a material

fact in any earlier communication with respect to the solicitation of proxies for the Company Stockholders’ Meeting which has become

false or misleading. Notwithstanding the foregoing, no representation is made by such Seller with respect to the information that has

been or will be supplied by any other Seller, any of the Acquiring Companies, any of the Santersus Companies or any of their respective

Representatives for inclusion in the Registration Statement or the Proxy Statement.

4.5

Ownership of Company Stock; Affiliates. Other than as set forth on Part 4.5 of the Santersus Disclosure Schedules,

such Seller (including such Seller’s Affiliates) does not own, directly or indirectly, beneficially or of record, any shares of

Company capital stock, Company Preferred Stock or any other economic interest (through derivative securities or otherwise) in, Company.

Other than as contemplated by this Agreement, no Seller is, nor at any time during the last three (3) years has been, an “interested

stockholder” of Company within the meaning of Nevada Revised Statutes 78.411-78.444. Except as set forth on Part 4.5 of the

Santersus Disclosure Schedule, no Seller is an “affiliate” of any other Seller as such term is defined in Rule 12b-2 of the

Exchange Act.

4.6

Securities Law Matters. Such Seller is an “accredited investor” as such term is defined in Rule 501(a) of

Regulation D promulgated under the Securities Act. Such Seller is acquiring the shares of Company Common Stock at the Closing for its

own account for investment only, and not with a view to, or for sale in connection with, any “distribution” (within the meaning

of the Securities Act) of such shares in violation of the Securities Act or any rule or regulation under the Securities Act. Such Seller

has had adequate opportunity to obtain from representatives of Company such information about Company as is necessary for such Seller

to evaluate the merits and risks of its acquisition of the shares of Company Common Stock at the Closing. Such Seller has reviewed the

risk factors disclosed in Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2025 as filed with the SEC.

Such Seller has sufficient expertise in business and financial matters to be able to evaluate the risks involved in the acquisition of

the shares of Company Common Stock at the Closing and to make an informed investment decision with respect to such acquisition. Such Seller

understands that the issuance of such shares has not been registered under the Securities Act and such shares are “restricted securities”

within the meaning of Rule 144 under the Securities Act; and the shares cannot be sold, transferred or otherwise disposed of unless they

are registered under the Securities Act (as contemplated by Section 6.1 or otherwise) or an exemption from registration is then

available. Such Seller represents that such Seller is familiar with Rule 144 promulgated under the Securities Act and understands the

resale restrictions imposed by Rule 144 and the Securities Act.

4.7

No Brokers. No broker, finder or investment banker is entitled to any brokerage, finder’s or other fee or commission

from such Seller or any of its Affiliates in connection with the transactions contemplated hereby based upon arrangements made by or on

behalf of such Seller.

4.8

Exclusivity of Representations; Reliance.

(a)

Except as expressly set forth in this Article 4, neither Sellers nor any Person on behalf of Sellers has made, nor are any

of them making, any representation or warranty, written or oral, express or implied, at law or in equity, including with respect to merchantability

or fitness for any particular purpose, in respect of Company or any of its Subsidiaries or Sellers in connection with the Contemplated

Transactions, including any representations or warranties about the accuracy or completeness of any information or documents previously

provided (including with respect to any financial or other projections therein), and any other such representations and warranties are

hereby expressly disclaimed.

(b)

Each Seller acknowledges and agrees that, except for the representations and warranties of Company set forth in Article 3,

none of such Seller or any of such Seller’s Representatives are relying on any other representation or warranty of Company or any

other Person made outside of Article 3, including regarding the accuracy or completeness of any such other representations or warranties

or the omission of any material information, whether express or implied, in each case with respect to the Contemplated Transactions.

Article

CONDUCT OF BUSINESS PENDING THE CLOSING

5.1

Conduct of Company Business. Except (v) as set forth on Schedule 5.1, (w) as expressly contemplated by this Agreement,

(x) as required by applicable Legal Requirements, or (y) unless Santersus shall otherwise consent in writing (such consent not to be unreasonably

withheld, delayed or conditioned), during the period from the date hereof and continuing until the earlier of the termination of this

Agreement pursuant to its terms or the Closing (the “Pre-Closing Period”), Company shall, and shall cause its

Subsidiaries to, conduct their respective businesses and operations (1) in the ordinary course of business consistent with past practice

and (2) in compliance in all material respects with all applicable Legal Requirements and requirements of all Contracts that constitute

Company Contracts. In addition, without limiting the foregoing, other than as expressly contemplated by this Agreement (including the

actions set forth on Schedule 5.1 and the proviso set forth in the first sentence of this Section 5.1), or with the prior

written consent of Santersus (which consent shall not be unreasonably withheld, delayed or conditioned), Company will not, and will not

permit its Subsidiaries to:

(a)

amend or otherwise change any of the Organizational Documents of any Acquiring Company or effect or be a party to any merger, consolidation,

share exchange business combination, recapitalization, reclassification of shares, stock split, reverse stock split or similar transaction

except, for the avoidance of doubt, the Contemplated Transactions;

(b)

issue, sell, pledge, dispose of or encumber (except for Permitted Encumbrances), or authorize the issuance, sale, pledge, disposition

or encumbrance of, any shares of capital stock of any class, or any options, warrants, convertible securities or other rights of any kind

to acquire any shares of capital stock, or any other ownership interest (including any phantom interest) (except for the issuance of shares

of Company Common Stock issuable pursuant to Company Options or Company Restricted Stock in accordance with the terms under the Company

Option Plan or pursuant to Company Warrants, as the case may be, which Company Options, Company Restricted Stock or Company Warrants,

as the case may be, are outstanding on the date hereof);

(c)

redeem, repurchase or otherwise acquire, directly or indirectly, any shares of Company Common Stock (other than pursuant to a Contract

in effect on the date of this Agreement and which has been made available to Santersus prior to the date hereof);

(d)

extend credit for borrowed money to any Person or incur any indebtedness for borrowed money or guarantee any indebtedness for borrowed

money or issue or sell any debt securities or guarantee any debt securities or other obligations of any other Person or sell, pledge,

dispose of or create an Encumbrance with respect to any assets (except for Encumbrances created by operation of law or dispositions of

obsolete or worthless assets or Permitted Encumbrances);

(e)

accelerate, amend or change the period (or permit any acceleration, amendment or change) of exercisability of any Company Options

or Company Warrants or authorize cash payments in exchange for any Company Options or Company Warrants, except as may be required under

any Company Option Plan, Contract or this Agreement or as may be required by applicable Legal Requirements;

(f)

(i) declare, set aside, make or pay any dividend or other distribution (whether in cash, stock or property or any combination thereof)

in respect of any of its capital stock, except that a wholly owned Subsidiary may declare and pay a dividend to its parent, (ii) split,

combine or reclassify any of its capital stock or issue or authorize or propose the issuance of any other securities in respect of, in

lieu of or in substitution for shares of its capital stock or (iii) amend the terms of, repurchase, redeem or otherwise acquire, or permit

any Subsidiary to repurchase, redeem or otherwise acquire, any of its securities or any securities of its Subsidiaries, or propose to

do any of the foregoing;

(g)

sell, assign, transfer, license, sublicense or otherwise dispose of any IP Rights (except for Permitted Encumbrances), other than

in the ordinary course of business (which shall include material transfer agreements, clinical trial-related agreements (including Contracts

with clinical research organizations), services agreements, non-disclosure agreements and other ordinary course Contracts with non-exclusive

licenses (including with research institutes));

(h)

materially change any royalty payment charged by Company or any of its Subsidiaries or materially change any royalty payment charged

by Persons who have licensed IP Rights to Company or any of its Subsidiaries;

(i)

form any Subsidiary;

(j)

acquire (by merger, consolidation, or acquisition of stock or assets) any corporation, partnership or other business organization

or division thereof or any other material property or assets or any equity interest or other interest in any other Entity or enter into

a joint venture with any other Entity;

(k)

forgive any loans to any Person, including its employees, officers, directors or Affiliates;

(l)

except as may be required under any Company Option Plan, Company Contract or this Agreement or as may be required by applicable

Legal Requirements, (i) increase the compensation payable or to become payable to its directors, officers, employees or consultants, (ii)

grant any severance, change in control, retention or termination pay to, or enter into any employment, severance or similar agreement

with, any director, officer, employee or consultant, (iii) hire any new employee or consultant whose annual base salary is more than $100,000

per year, (iv) establish, adopt, enter into, terminate or amend in any material respect any collective bargaining or similar agreement

or Company Employee Plan (or any plan, program, agreement or arrangement that would be a Company Employee Plan if it were in existence

on the date hereof), or take any action to accelerate the time of payment or vesting of any compensation or benefits or take any action

to fund or secure the funding of any compensation or benefits (other than qualified retirement plan benefits);

(m)

take any action, other than as required by applicable Legal Requirements or GAAP, to change accounting policies or procedures;

(n)

(i) make or change any material Tax election inconsistent with past practices, (ii) change any material Tax accounting method or

(iii) settle or compromise any material federal, state, local or foreign Tax Liability, except, in the case of clauses (i) and (ii), as

required by Legal Requirements;

(o)

pay, discharge or satisfy any claims or Liabilities (absolute, accrued, asserted or unasserted, contingent or otherwise), other

than the payment, discharge or satisfaction in the ordinary course of business and consistent with past practice of Liabilities reflected

or reserved against in the Company Financials, or incurred in the ordinary course of business and consistent with past practice;

(p)

enter into any partnership arrangements, joint development agreements or material strategic alliances;

(q)

enter into any Contract (i) involving annual payments by Company or any of its Subsidiaries greater than $500,000 in the aggregate,

(ii) involving indemnification by Company or any of its Subsidiaries, other than in the ordinary course of business, (iii) relating to

IP Rights (other than confidentiality agreements, assignment of inventions agreements between any Acquiring Company and any employee thereof

and non-exclusive licenses in the ordinary course of business), and/or (iv) that is not terminable for convenience without penalty;

(r)

amend in any material respect or terminate (except as provided in Section 6.22) any Company Contract;

(s)

make any capital expenditure or capital commitment in excess of $100,000;

(t)

initiate any litigation, action, suit, proceeding, claim or arbitration (each, an “Action”), for repayment

of amounts in dispute, or settle or agree to settle any Action, other than any settlement which (i) provides a complete release of all

claims against Company and (ii) that does not involve the payment of any amount by Company in excess of $100,000 (after giving effect

to any insurance coverage applicable to such settlement) (except for any Action arising out of or related to this Agreement or the Contemplated

Transactions);

(u)

fail to make any material payment with respect to any of Company’s or any of its Subsidiaries’ accounts payable or

indebtedness in a timely manner in accordance with the terms thereof and consistent with past practices;

(v)

enter into or amend a Contract that would reasonably be expected to prevent or materially impede, interfere with, hinder or delay

the consummation of the Contemplated Transactions; or

(w)

take, or agree in writing or otherwise to take, any of the actions described in Sections 5.1(a) through 5.1(v) above.

The Parties acknowledge and

agree that (i) nothing contained in this Agreement shall give Santersus, directly or indirectly, the right to control or direct the operations

of any Acquiring Company prior to the Closing, (ii) prior to the Closing, each Acquiring Company shall exercise, consistent with the terms

and conditions of this Agreement, complete control over its operations and (iii) notwithstanding anything to the contrary set forth in

this Agreement, no consent of Santersus will be required with respect to any matter set forth in this Agreement to the extent the requirement

of such consent would violate any applicable Legal Requirements.

5.2

Conduct of Santersus Business. Except as set forth on Schedule 5.2, as expressly contemplated by this Agreement,

as required by applicable Legal Requirements or unless Company shall otherwise consent in writing (such consent not to be unreasonably

withheld, delayed or conditioned), during the Pre-Closing Period, Santersus shall, and shall cause its Subsidiaries to, conduct their

respective businesses and operations (a) in the ordinary course of business consistent with past practice and (b) in compliance in all

material respects with all applicable Legal Requirements and the requirements of all Contracts that constitute Santersus Contracts. In

addition, without limiting the foregoing, other than as expressly contemplated by this Agreement (including the actions set forth on Schedule

5.2 and the proviso set forth in the first sentence of this Section 5.2), or with the prior written consent of Company (which

consent shall not be unreasonably withheld, delayed or conditioned), Santersus will not, and will not permit its Subsidiaries to:

(a)

amend or otherwise change any of the Organizational Documents of any Santersus Company (other than in connection with the Santersus

Share Conversion) or effect or be a party to any merger, consolidation, share exchange business combination, recapitalization, reclassification

of shares, stock split, reverse stock split or similar transaction except, for the avoidance of doubt, the Contemplated Transactions;

(b)

issue, sell, pledge, dispose of or encumber (except for Permitted Encumbrances), or authorize the issuance, sale, pledge, disposition

or encumbrance of, any shares of capital stock of any class, or any options, warrants, convertible securities or other rights of any kind

to acquire any shares of capital stock, or any other ownership interest (including any phantom interest) (except for the issuance of (i)

Santersus Ordinary Shares pursuant to Santersus Options granted prior to the date hereof in accordance with the terms of the Santersus

Option Plan and (ii) Santersus Ordinary Shares in the Santersus Share Conversion);

(c)

except for the Santersus Share Conversion, redeem, repurchase or otherwise acquire, directly or indirectly, any Santersus Shares;

(d)

extend credit for borrowed money to any Person or incur any indebtedness for borrowed money or guarantee any indebtedness for borrowed

money or issue or sell any debt securities or guarantee any debt securities or other obligations of others or sell, pledge, dispose of

or create an Encumbrance with respect to any assets (except for Encumbrances created by operation of law or dispositions of obsolete or

worthless assets or Permitted Encumbrances);

(e)

accelerate, amend or change the period (or permit any acceleration, amendment or change) of exercisability of options or authorize

cash payments in exchange for any options, except as provided in Section 6.15 hereof;

(f)

(i) declare, set aside, make or pay any dividend or other distribution (whether in cash, stock or property or any combination thereof)

in respect of any Santersus Shares, except that a wholly owned Subsidiary may declare and pay a dividend to its parent, (ii) split, combine

or reclassify any Santersus Shares or, except for the Santersus Share Conversion and except as specifically provided in Section 6.15

with respect to Santersus Options, issue or authorize or propose the issuance of any other securities in respect of, in lieu of or in

substitution for Santersus Shares or (iii) amend the terms of, repurchase, redeem or otherwise acquire, or permit any Subsidiary to repurchase,

redeem or otherwise acquire, any of its securities or any securities of its Subsidiaries, or propose to do any of the foregoing;

(g)

sell, assign, transfer, license, sublicense or otherwise dispose of any Santersus IP Rights (except for Permitted Encumbrances),

other than in the ordinary course of business (which shall include material transfer agreements, clinical trial-related agreements (including

Contracts with clinical research organizations), services agreements, non-disclosure agreements and other ordinary course Contracts with

non-exclusive licenses (including with research institutes)) and the Organox Agreement;

(h)

materially change any royalty payments charged by any Santersus Company or materially change any royalty payments charged by Persons

who have licensed IP Rights to any Santersus Company other than in the ordinary course of business;

(i)

form any Subsidiary;

(j)

acquire (by merger, consolidation, or acquisition of stock or assets) any corporation, partnership or other business organization

or division thereof or any other material property or assets or any equity interest or other interest in any other Entity or enter into

a joint venture with any other Entity;

(k)

forgive any loans to any Person, including its employees, officers, directors or Affiliates;

(l)

take any action, other than as required by applicable Legal Requirements or GAAP, to change accounting policies or procedures;

(m)

(i) make or change any material Tax election inconsistent with past practices, (ii) change any material Tax accounting method or

(iii) settle or compromise any material federal, state, local or foreign Tax Liability, except, in the case of clauses (i) and (ii), as

required by Legal Requirements;

(n)

pay, discharge or satisfy any claims or Liabilities (absolute, accrued, asserted or unasserted, contingent or otherwise), other

than the payment, discharge or satisfaction of Liabilities incurred in the ordinary course of business and consistent with past practice

or otherwise incurred in connection with the Contemplated Transactions;

(o)

other than in the ordinary course of business, enter into, materially amend or terminate any Santersus Contract;

(p)

enter into or amend a Contract that would reasonably be expected to prevent or materially impede, interfere with, hinder or delay

the consummation of the Contemplated Transactions;

(q)

settle or agree to settle any Action, other than in the ordinary course of business;

(r)

take, or agree in writing or otherwise to take, any of the actions described in Sections 5.2(a) through (q) above.

The Parties acknowledge and

agree that (i) nothing contained in this Agreement shall give Company, directly or indirectly, the right to control or direct the operations

of any Santersus Company prior to the Closing, (ii) prior to the Closing, each Santersus Company shall exercise, consistent with the terms

and conditions of this Agreement, complete control over its operations and (iii) notwithstanding anything to the contrary set forth in

this Agreement, no consent of Company will be required with respect to any matter set forth in this Agreement to the extent the requirement

of such consent would violate any applicable Legal Requirements.

Article

ADDITIONAL AGREEMENTS

6.1

Registration Statement; Proxy Statement.

(a)

On or before the later of (x) forty-five (45) days after the date of this Agreement or (y) ten (10) days after Company’s

receipt of the Santersus Financials and any other information reasonably requested by the Company for inclusion in the Proxy Statement

and Registration Statement (each as defined below), Company, in cooperation with Santersus, shall prepare and file with the SEC a preliminary

proxy statement relating to the Company Stockholders’ Meeting to be held in connection with the Contemplated Transactions (the definitive

form of such proxy statement, together with any amendments thereof or supplements thereto, the “Proxy Statement”).

Company, in cooperation with Santersus, shall use commercially reasonable efforts to, concurrently with the Proxy Statement, prepare and

file with the SEC a resale registration statement on Form S-1 (the “Registration Statement”), in connection

with the registration under the Securities Act of the resale of the shares of Company Common Stock to be issued in the Contemplated Transactions.

Company will, reasonably promptly following the receipt thereof, make available to Santersus any SEC correspondence related to the Proxy

Statement and Registration Statement. Each of Company and Santersus shall use their commercially reasonable efforts to cause the Registration

Statement to become effective as promptly as practicable, and shall take all or any action required under any applicable federal, state,

securities and other Legal Requirements in connection with the issuance of shares of Company Common Stock in the Contemplated Transactions.

Each of Company, Santersus and Sellers shall furnish all information concerning such Party, such Party’s Subsidiaries and such Party’s

directors, executive officers and shareholders, as applicable, to the other parties as the other parties may reasonably request in connection

with such actions and the preparation of the Proxy Statement and Registration Statement. Company covenants and agrees that the Proxy Statement

and Registration Statement (and the letter to stockholders, notice of meeting and form of proxy included therewith) will not contain any

untrue statement of a material fact or omit to state any material fact required to be stated therein or necessary in order to make the

statements made therein, in light of the circumstances under which they were made, not misleading. Santersus covenants and agrees that

the information supplied by Santersus to Company for inclusion in the Proxy Statement and Registration Statement will not contain any

untrue statement of a material fact or omit to state any material fact required to be stated therein or necessary in order to make such

information, in light of the circumstances under which they were made, not misleading. Notwithstanding the foregoing, Company makes no

covenant, representation or warranty with respect to statements made in the Proxy Statement or Registration Statement (and the letter

to stockholders, notice of meeting and form of proxy included therewith), if any, based on information provided by or on behalf of Santersus

or any of its Representatives for inclusion therein. Company shall use commercially reasonable efforts to cause the Proxy Statement to

be mailed to its stockholders as promptly as practicable (but within five (5) Business Days) after the date the SEC advises that it has

no further comments thereon or that Company may commence mailing the Proxy Statement (which advice will be deemed to have been received

if the SEC has not affirmatively notified Company prior to the eleventh (11th) calendar day after filing the preliminary Proxy Statement

that the SEC will or will not be reviewing the Proxy Statement, the “Clearance Date”). If Company or Santersus

become aware of any event or information that, pursuant to the Securities Act or the Exchange Act, should be disclosed in an amendment

or supplement to the Proxy Statement or Registration Statement, then such party shall promptly inform the other parties thereof and shall

cooperate with such other parties in filing such amendment or supplement with the SEC and, if appropriate, in mailing such amendment or

supplement to the Company Stockholders.

(b)

Notwithstanding anything to the contrary stated above, prior to filing and mailing, as applicable, the Proxy Statement or Registration

Statement (or any amendment or supplement thereto) or responding to any comments of the SEC with respect thereto, Company shall provide

Santersus a reasonable opportunity to review and comment on such document or response and shall discuss with Santersus and include in

such document or response, comments reasonably and promptly proposed by Santersus, unless made pursuant to a telephone call

initiated by the SEC. Company will advise Santersus, promptly after Company receives notice thereof, of the time when the Registration

Statement has become effective or any supplement or amendment has been filed, of the issuance of any stop order or the suspension of the

qualification of Company Common Stock for offering or sale in any jurisdiction, of the initiation or threat of any proceeding for any

such purpose, or of any request by the SEC for the amendment or supplement of the Proxy Statement or Registration Statement or for additional

information.

(c)

Santersus shall provide Company, as promptly as reasonably practicable after the date hereof, any audited or unaudited consolidated

balance sheets and the related audited or unaudited consolidated income statements, statements of cash flows and members’ equity

of Santersus as of and for a year-to-date period ended as of the end of any other different fiscal quarter (and as of and for the same

period from the previous fiscal year) or fiscal year, as applicable that is required to be included in the Proxy Statement or Registration

Statement. Santersus shall be available, and shall use commercially reasonable efforts to make its officers, managers, representatives

and employees available, in each case, during normal business hours and upon reasonable advanced notice, to Company and its advisors in

connection with (i) the drafting of the Proxy Statement and Registration Statement and (ii) responding in a timely manner to comments

on the Proxy Statement and Registration Statement from the SEC. Without limiting the generality of the foregoing, Santersus shall cooperate

with Company in connection with the preparation for inclusion in the Proxy Statement and Registration Statement of pro forma financial

statements that comply with the requirements of Regulation S-X under the rules and regulations of the SEC (as interpreted by the staff

of the SEC).

6.2

Company Stockholders’ Meeting; Company Board Recommendation.

(a)

Company will take all action reasonably necessary under applicable Legal Requirements to call, give notice of and hold a meeting

of the holders of Company Common Stock (the “Company Stockholders’ Meeting”) to approve the Company Stockholder

Approval Matters. The Company Stockholders’ Meeting will be held as promptly as practicable following the Clearance Date (on a date

selected by Company in consultation with Santersus) but in no event later than forty-five (45) days after filing the definitive Proxy

Statement; provided, however, notwithstanding anything to the contrary contained herein, if on the date of the Company Stockholders’

Meeting, or a date preceding the date on which the Company Stockholders’ Meeting is scheduled, Company reasonably believes that

(i) it will not receive proxies sufficient to obtain the required approval of the holders of Company Common Stock at the Company Stockholders’

Meeting with respect to all of the Company Stockholder Approval Matters, whether or not a quorum would be present at the Company Stockholders’

Meeting or (ii) it will not have sufficient shares of Company Common Stock represented (whether in person or by proxy) to constitute a

quorum necessary to conduct the business of the Company Stockholders’ Meeting, Company shall have the right, in its sole and absolute

discretion, to postpone or adjourn the Company Stockholders’ Meeting as long as the date of the Company Stockholders’ Meeting

is not postponed or adjourned more than an aggregate of forty-five (45) consecutive calendar days in connection with such postponement

or adjournment. Company will engage Okapi Partners LLC (or such other proxy solicitor reasonably acceptable to Santersus) as proxy solicitor

(the “Proxy Solicitor”) to assist in the solicitation of proxies in connection with the Company Stockholders’

Meeting and will ensure that such proxies are solicited in compliance in all material respects with all applicable Legal Requirements.

Company shall use its commercially reasonable efforts to solicit from the Company Stockholders proxies in favor of the Company Stockholder

Approval Matters; provided, however, that if Company does not obtain the Company Stockholder Approval at the first meeting

of shareholders following the date hereof, Company shall use reasonable best efforts to call a meeting no later than forty-five (45) days

thereafter to seek Company Stockholder Approval until the earlier of the date on which Company Stockholder Approval is obtained or this

Agreement is terminated in accordance with Article 8; provided that the Company may call a subsequent meeting later than forty-five

(45) days after a meeting at which Company does not obtain the Company Stockholder Approval with the prior consent of Santersus, such

consent not to be unreasonably withheld, conditioned or delayed.

(b)

Company agrees that, subject to this Section 6.2, (i) the board of directors of Company will recommend that its stockholders

vote to approve the Company Stockholder Approval Matters (such recommendation, the “Company Board Recommendation”);

(ii) the Proxy Statement will include the Company Board Recommendation; (iii) the Company Board Recommendation will not be withdrawn or

modified, and no resolution by the board of directors of Company or any committee thereof to withdraw or modify the Company Board Recommendation

will be adopted or publicly proposed by Company; (iv) following the public disclosure of an Acquisition Proposal, the board of directors

of Company will not fail to publicly reaffirm or republish the Company Board Recommendation within five (5) Business Days after Santersus

so requests in writing; provided, that Santersus may make no more than two such requests (and no more than one such request in

any 30-day period) with respect to any Acquisition Proposal and one additional request with respect to each material amendment or modification

thereto; provided, further, that Company shall not be required to make any such reaffirmation or republication if the board

of directors of Company determines in good faith, after consultation with its outside legal counsel and outside financial advisors, that

doing so would reasonably be expected to be inconsistent with its fiduciary duties under applicable Legal Requirements; provided,

further, that any failure by the board of directors of Company to publicly reaffirm the Company Board Recommendation following

a request by Santersus under this clause (iv) (other than a failure permitted by the immediately preceding proviso) shall constitute a

Company Change in Recommendation for purposes of this Agreement, and (v) the board of directors of Company will not fail to recommend

against acceptance of, or take a neutral position with respect to, a tender or exchange offer related to an Acquisition Proposal in any

position taken pursuant to Rules 14d-9 and 14e-2 under the Exchange Act, except to the extent the board of directors of Company determines

in good faith, after consultation with its outside legal counsel and outside financial advisors, that taking such position would reasonably

be expected to be inconsistent with its fiduciary duties under applicable Legal Requirements.

(c)

Notwithstanding anything to the contrary contained in Section 6.2(b), at any time prior to the Company Stockholder Approval,

the Company Board Recommendation may be withdrawn or modified (a “Company Change in Recommendation”) and the

Company may terminate this Agreement pursuant to Section 8.1(h) to enter into an agreement with respect to such bona fide Acquisition

Proposal if the board of directors of Company concludes in good faith, after consultation with Company’s outside legal counsel and

financial advisors, that as a result of Company’s receipt of such Acquisition Proposal that was not the result of a breach of Section

6.10(a)(i) and that the board of directors of Company has determined in good faith, after consultation with Company’s outside

legal and financial advisors, constitutes a Superior Offer, a failure to make a Company Change in Recommendation is reasonably likely

to constitute a breach of the fiduciary duties of the board of directors of Company to the Company Stockholders under applicable Legal

Requirements; provided, however, that prior to Company taking any action permitted under this Section 6.2(c), Company

shall provide Santersus and Sellers with four (4) Business Days’ prior written notice (the “Notice Period”)

advising Santersus and Sellers that it intends to effect such withdrawal or modification to the Company Board Recommendation and specifying,

in reasonable detail, the reasons therefor (including the information required by Section 6.10(a)(ii)), and during such Notice

Period, (i) Company shall negotiate, and cause its Representatives to negotiate, with Santersus in good faith (to the extent Santersus

wishes to negotiate) to enable Santersus to determine whether to propose revisions to the terms of this Agreement such that it would obviate

the need for Company’s board of directors to effect such withdrawal or modification and (ii) Company shall consider in good faith

any proposal by Santersus or Sellers to amend the terms and conditions of this Agreement in a manner such that the Acquisition Proposal

would cease to be a Superior Offer. If the board of directors of Company determines that, in accordance with clause (ii) of the immediately

preceding sentence, Santersus’ or Sellers’ modified proposal results in the Acquisition Proposal ceasing to be a Superior

Offer (after taking into account any amendment or modification to the terms of such Superior Offer), then the board of directors of Company

shall maintain the Company Board Recommendation; provided, however, that in the event of any material amendment or modification

to the terms of such Superior Offer which continues to constitute a Superior Offer, the notification provisions above shall again apply,

except that the Notice Period shall be three (3) Business Days rather than four (4) Business Days.

(d)

Nothing contained in this Agreement will prohibit Company or its board of directors from (i) making any disclosure or statement

pursuant to Rules 14d-9 and 14e-2(a) promulgated under the Exchange Act or Item 1012(a) of Regulation M-A promulgated under the Exchange

Act (or any similar communications to stockholders of the Company), (ii) making any “stop, look and listen” communication

to the stockholders of the Company pursuant to Rule 14d-9(f) under the Exchange Act (or any similar communications to stockholders of

the Company) or (iii) making any disclosure to the stockholders of the Company if the board of directors of the Company determines in

good faith, after consultation with its outside legal counsel and outside financial advisors, that the failure to make such disclosure

would reasonably be expected to be inconsistent with the Company board of directors’ fiduciary duties under applicable Legal Requirements.

Company shall not withdraw or modify in a manner adverse to Santersus the Company Board Recommendation unless specifically permitted pursuant

to this Section 6.2.

(e)

In circumstances not involving an Acquisition Proposal, the board of directors of the Company may make a Company Change in Recommendation

in response to an Intervening Event if, and only if, after the date of this Agreement, (i) the board of directors of the Company determines

in good faith (after consultation with its outside legal advisors) that the failure to do so would be inconsistent with its fiduciary

duties under applicable Legal Requirements; (ii) Company shall have given Santersus a notice at least four (4) Business Days prior to

making any such Company Change in Recommendation; and (iii)(A) Company shall have specified the Intervening Event in reasonable detail,

including the material facts and circumstances related to the applicable Intervening Event, (B) Company shall have given Santersus the

four (4) Business Days after the notice to propose revisions to the terms of this Agreement or make another proposal, and shall have made

its Representatives reasonably available to negotiate in good faith with Santersus (to the extent Santersus desires to do so) with respect

to such proposed revisions or other proposal, if any, and (C) after considering the results of any such negotiations and giving effect

to the proposals made by Santersus, if any, after consultation with outside legal counsel, the board of directors of Company shall have

determined, in good faith, that the failure to make the Company Change in Recommendation in response to such Intervening Event or terminate

this Agreement pursuant to Section 8.1(g) would be inconsistent with the fiduciary duties of the board of directors of

the Company to Company’s stockholders under applicable Legal Requirements. For the avoidance of doubt, the provisions of this Section

6.2(e) shall also apply to any material change to the facts and circumstances relating to such Intervening Event and require a new

notice to Santersus, except that the references to four (4) Business Days shall be deemed to be two (2) Business Days.

(f)

Unless the board of directors of Company has effected a Company Change in Recommendation in accordance with this Section 6.2

and this Agreement is otherwise terminated pursuant to Section 8.1, Company’s obligation to call, give notice of and hold

the Company Stockholders’ Meeting in accordance with this Section 6.2 shall not be limited or otherwise

affected by the commencement, disclosure, announcement or submission of any Superior Offer or Acquisition Proposal, or by any Company

Change in Recommendation.

6.3

Access to Information; Confidentiality. During the Pre-Closing Period, and upon reasonable notice and subject to restrictions

contained in confidentiality agreements to which such Party is subject, Company and Santersus each shall, and shall use commercially reasonable

efforts to cause such Party’s Representatives to, afford to the Representatives of the other, reasonable access, during the Pre-Closing

Period, to all its properties, books, contracts, commitments and records (including Tax records) and, during such period, Company and

Santersus each will furnish promptly to the other all information concerning its business, properties and personnel as such other Party

may reasonably request, and each will make available to the other the appropriate individuals (including attorneys, accountants and other

professionals) for discussion of the other’s business, properties and personnel as either Party may reasonably request. Any investigation

conducted by Company or Santersus pursuant to this Section 6.3 shall be conducted during normal business hours, with reasonable

advance notice and in such a manner as not to interfere unreasonably with the conduct of the business of the other Party. Each Party will

keep such information confidential in accordance with the terms of the confidentiality agreement dated February 4, 2025 (the “Confidentiality

Agreement”) between Santersus and Company, which agreements the parties agree will continue in full force following the

date of this Agreement. Notwithstanding anything herein to the contrary in this Section 6.3, no access or examination contemplated

by this Section 6.3 shall be permitted to the extent that it would require any Party or its Subsidiaries to waive the attorney-client

privilege or attorney work product privilege, or violate any applicable Legal Requirement; provided, that such Party or its Subsidiary:

(i) shall be entitled to withhold only such information that may not be provided without causing such violation or waiver; (ii) shall

provide to the other Party all related information that may be provided without causing such violation or waiver (including, to the extent

permitted, redacted versions of any such information); and (iii) shall enter into such effective and appropriate joint-defense agreements

or other protective arrangements as may be reasonably requested by the other Party in order that all such information may be provided

to the other Party without causing such violation or waiver.

6.4

Regulatory Approvals and Related Matters.

(a)

Each Party will promptly file all notices, reports and other documents required to be filed by such Party with any Governmental

Body with respect to the Contemplated Transactions, and submit promptly any additional information requested by any such Governmental

Body. Each of Santersus and Company will notify the other promptly upon the receipt of (and, if in writing, share a copy of) any communication

received by such Party from, or given by such Party to, any Governmental Bodies and of any material communication received or given in

connection with any proceeding by a private party, in each case in connection with the Contemplated Transactions. Without limiting the

generality of the foregoing, the Parties shall, promptly after the date of this Agreement, prepare and file any notification or other

document required to be filed in connection with the Acquisition under any applicable foreign Legal Requirement relating to antitrust

or competition matters. Company and Santersus shall respond as promptly as is practicable to respond in compliance with: (i) any inquiries

or requests received from the Federal Trade Commission or the Department of Justice for information or documentation; and (ii) any inquiries

or requests received from any state attorney general, foreign antitrust or competition authority or other Governmental Body in connection

with antitrust or competition matters. Each of Santersus and Company will give the other prompt notice of the commencement or known threat

of commencement of any Legal Proceeding by or before any Governmental Body with respect to any of the Contemplated Transactions, will

keep the other reasonably informed as to the status of any such Legal Proceeding or threat, and, in connection with any such Legal Proceeding,

will permit authorized representatives of the other to be present at each meeting or conference relating to any such Legal Proceeding

and to have access to and be consulted in connection with any document, opinion or proposal made or submitted to any Governmental Body

in connection with any such Legal Proceeding.

(b)

Upon the terms and subject to the conditions set forth in this Agreement and subject to this Section 6.4(b), each of the

Parties agrees to use its commercially reasonable efforts to take, or cause to be taken, all actions necessary or advisable to satisfy

each of the conditions set forth in Article 7, consummate the Acquisition and make effective the other Contemplated Transactions

(provided that no Party will be required to waive any of the conditions set forth in Article 7, as applicable, as part of

its obligations to consummate the Contemplated Transactions). Without limiting the generality of the foregoing, but subject to this Section

6.4(b), each Party agrees to use its commercially reasonable efforts to: (i) as promptly as practicable, prepare and file all filings

(if any) and give all notices (if any) required to be made and given by such Party in connection with the Contemplated Transactions; (ii)

obtain each Consent (if any) required to be obtained (pursuant to any applicable Legal Requirement or Contract, or otherwise) by such

Party in connection with the Contemplated Transactions; and (iii) lift any restraint, injunction or other legal bar to the Contemplated

Transactions.

6.5

Director Indemnification and Insurance.

(a)

From the Closing through the sixth (6th) anniversary of the Closing Date, Company shall indemnify and hold harmless each person

who is now, or has been at any time prior to the date hereof, or who becomes prior to the Closing, a director or officer of any Santersus

Company or a director or officer of the Company (the “D&O Indemnified Parties”), against all claims, losses,

Liabilities, damages, judgments, fines and reasonable fees, costs and expenses, including attorneys’ fees and disbursements, incurred

in connection with any claim, action, suit, proceeding or investigation, whether civil, criminal, administrative or investigative, arising

out of or pertaining to the fact that the D&O Indemnified Party is or was a director or officer of a Santersus Company or the Company,

whether asserted or claimed prior to, at or after the Closing, to the fullest extent permitted under applicable Legal Requirement, and

such Santersus Company’s or the Company’s Organizational Documents, as applicable. Each D&O Indemnified Party will, to

the fullest extent permitted under applicable Legal Requirements and the Santersus Company’s or the Company’s Organizational

Documents, as applicable, be entitled to advancement of expenses incurred in the defense of any such claim, action, suit, proceeding or

investigation from the applicable Santersus Company or the Company, jointly and severally, upon receipt by Company or Santersus from the

D&O Indemnified Party of a request therefor; provided that any person to whom expenses are advanced provides an undertaking,

to the extent then required by applicable Legal Requirement, to repay such advances if it is ultimately determined that such person is

not entitled to indemnification.

(b)

From and after the Closing, Company shall maintain directors’ and officers’ liability insurance policies for Company

and its Subsidiaries, including Santersus and its Subsidiaries, with an effective date as of the Closing Date, on commercially available

terms and conditions and with coverage limits customary for U.S. public companies similarly situated to Company. In addition, in connection

with the Closing, Company and Santersus shall purchase and fully pre-pay (which expense shall be paid 50% by the Company and 50% by Santersus,

subject to this Section 6.5(b)) a “tail” endorsement for the Company’s existing directors’ and officers’

insurance policies and Company’s existing fiduciary liability insurance policies, in each case, that provides a six-year extended

reporting period from and after the Closing for claims first made against an individual insured for any alleged or actual wrongful act(s)

that occurred prior to the Closing (including in connection with this Agreement or the Contemplated Transactions) (the “D&O

Tail”). In the event the D&O Tail is not available to be purchased from the Company’s existing directors’

and officers’ and/or fiduciary liability insurer(s) then the Company and Santersus shall purchase and fully pre-pay (which expense

shall be paid 50% by the Company and 50% by Santersus, subject to this Section 6.5(b)) the premium for directors’ and officers’

and fiduciary liability insurance policies which would be the equivalent of the D&O Tail with coverage that is substantially equivalent

to and in any event not less favorable than the Company’s current existing directors’ and officers’ and fiduciary liability

insurance and which cannot be cancelled for any reason. Notwithstanding anything herein to the contrary, Santersus’ expense obligations

hereunder shall be limited to 50% of a D&O Tail with annual premiums not in excess of 300% of the annual premiums paid by Company

in its last full fiscal year prior to the date hereof for Company’s current policies of directors’ and officers’ liability

insurance and fiduciary liability insurance (the “Annual Premium”); if such premiums for such D&O Tail would

exceed 300% of the Annual Premium, then Company may, in its sole discretion, either (i) pay the excess over 300% of the Annual Premium

and maintain full coverage, or (ii) purchase policies that provide the maximum coverage available at an annual premium equal to 300% of

the Annual Premium. Additionally, Santersus will obtain run-off “tail” endorsements to its current directors’ and

officers’ insurance policies (or runoff or “tail” policies of at least the same coverage containing terms and conditions

no less advantageous to the current and all former directors and officers of Santersus) with respect to acts or failures to act prior

to the Closing. Company shall pay all reasonable expenses, including reasonable attorneys’ fees, that may be incurred by the Persons

referred to in this Section 6.5 in connection with their enforcement of their rights provided in this Section 6.5 but only

if and to the extent that such Persons are successful on the merits of such enforcement action.

(c)

The provisions of this Section 6.5 are intended to be in addition to the rights otherwise available to the current and former

officers and directors of Santersus and Company by Legal Requirement, applicable Organizational Documents or agreement, and shall operate

for the benefit of, and shall be enforceable by, each of the D&O Indemnified Parties, their heirs and their representatives.

(d)

This Section 6.5 is intended to be (i) for the benefit of, and shall be enforceable by, the D&O Indemnified Parties,

their heirs and personal representatives and shall be binding on Santersus, Company and their respective successors and assigns, (ii)

in addition to, and not in substitution for, any other rights to indemnification or contribution that any D&O Indemnified Party may

have by contract or otherwise, including indemnification agreements that Company or Santersus have entered into with any of their respective

directors or officers and (iii) may not be amended, altered or repealed after the Closing without the prior written consent of the affected

D&O Indemnified Party (provided that, for the avoidance of doubt, such amendment, alteration or repeal prior to the Closing

shall be governed by Section 9.2).

(e)

In the event Company or Santersus or any of their respective successors or assigns (i) consolidates with or merges into any other

Person and shall not be the continuing or surviving corporation or entity of such consolidation or merger or (ii) transfers all or substantially

all of its properties and assets to any Person, then, and in each such case, proper provision shall be made so that the successors and

assigns of Company or Santersus, as the case may be, shall succeed to the obligations set forth in this Section 6.5.

6.6

Notification of Certain Matters.

(a)

Company will give prompt notice to Santersus and each Seller, Santersus will give prompt notice to Company and each Seller will

give prompt notice to Santersus and Company, of (i) the occurrence, or non-occurrence, of any event the occurrence, or non-occurrence,

of which would be likely to cause any representation or warranty contained in this Agreement to be untrue or inaccurate in a manner that

causes the condition set forth in Section 7.2(b) or Section 7.3(b), as applicable, not to be satisfied, and (ii) any failure

of Company, Santersus or such Seller, as the case may be, to materially comply with or materially satisfy any covenant, condition or

agreement to be complied with or satisfied by it hereunder.

(b)

Company, Santersus and each Seller will give prompt notice to the other of: (i) any notice or other communication from any Person

alleging that the consent of such Person is or may be required in connection with the Contemplated Transactions; (ii) any notice or other

communication from any Governmental Body in connection with the Contemplated Transactions; (iii) any litigation relating to or involving

or otherwise affecting Company, Santersus or such Seller that relates to the Contemplated Transactions; (iv) the occurrence of a default

or event that, with notice or lapse of time or both, will become a default under a Company Contract or a Santersus Contract, as applicable;

and (v) any change that would be considered reasonably likely to result in a Company Material Adverse Effect or a Santersus Material Adverse

Effect, as applicable.

(c)

No notification given to a Party pursuant to this Section 6.6 shall change, limit or otherwise affect any of the representations,

warranties, covenants or obligations of the Party providing such notification or any of such Party’s Subsidiaries contained in this

Agreement or the Company Disclosure Schedule or the Santersus Disclosure Schedule, as appropriate, for purposes of Section 7.2

or Section 7.3, as appropriate. The failure by a Party to give a notification required under this Section 6.6 or any delay

in providing such a required notification shall not be treated as a breach of covenant for the purposes of Section 7.2(a) or Section

7.3(a), as applicable, unless such failure or delay results in material prejudice to another Party.

6.7

Public Announcements. The initial press release relating to this Agreement shall be a joint press release, and thereafter

Santersus and Company will consult with each other before issuing any press release or otherwise making any public statements (including

disclosure under the Securities Act or Exchange Act) with respect to the Acquisition or this Agreement. No Party shall, and no Party shall

permit any of its Subsidiaries or Representatives to, issue any press release or make any such public statement (to any customers or employees

of such Party, to the public or otherwise) relating to the Acquisition without the prior consent of, in the case of (i) Company, Santersus,

(ii) Santersus, Company or (iii) a Seller, Santersus and Company, which will not be unreasonably withheld, conditioned or delayed; provided,

however, that (A) on the advice of outside legal counsel, Company may issue a press release or public statement without the consent

of Santersus if Company, with the advice of outside legal counsel, reasonably determines is required by Legal Requirements or otherwise

made in connection with a Company Change in Recommendation or the termination of this Agreement and (B) other than a press release announcing

a Company Change in Recommendation or the termination of this Agreement or a subsequent press release relating to such Company Change

in Recommendation or termination, any press release or public statement relating to the Acquisition to be issued without the consent of

Santersus pursuant to clause (A) shall be subject to reasonable prior notice to and review of Santersus and Company shall consider any

and all reasonable comments of Santersus thereon in good faith. Notwithstanding the foregoing, each of Company and Santersus may make

public statements in response to specific questions by the press, analysts, investors or those attending industry conferences or financial

analyst conference calls, so long as any such statements are consistent with previous press releases, public disclosures or public statements

made by Company or Santersus in compliance with this Section 6.7 and such statements do not result in the requirement to amend

or supplement the Registration Statement or the Proxy Statement and are not deemed to be a “free-writing prospectus” as such

term is defined under the Securities Act.

6.8

Conveyance Taxes. Each Party will cooperate in the preparation, execution and filing of all returns, questionnaires,

applications or other documents regarding any real property transfer or gains, sales, use, transfer, value added, stock transfer and stamp

Taxes, any transfer, recording, registration and other fees, and any similar Taxes which become payable in connection with the Contemplated

Transactions that are required or permitted to be filed on or before the Closing or in relation to stamp Taxes in respect of the transfers

of (or agreement to transfer) the Santersus Shares after the Closing. Without limiting the generality of the forgoing, Company shall not

have any Liability for any Tax incurred by Santersus or any Seller in connection with the Contemplated Transactions.

6.9 Board

of Directors and Officers. The Parties shall use reasonable best efforts and take all necessary action so that effective as

of the Closing, the Board of Directors of Company is comprised of eight (8) members, with two (2) of such members designated in

writing by Company prior to the expiration of the Designation Period (the “Company Directors”) and six (6)

of such members designated in writing by Santersus prior to the expiration of the Designation Period (the “Santersus

Directors”), each to be elected or appointed, as applicable, to the position of directors of Company, to serve in such

positions effective as of the Closing until successors are duly appointed and qualified in accordance with applicable Legal

Requirements. The Chairman of the Board of Directors of the Company, effective as of the Closing, shall be designated in writing by

Santersus prior to the expiration of the Designation Period. The persons designated in writing by Santersus during the Designation

Period to serve as officers of the Company shall be elected or appointed, as applicable, to the positions of officers of Company, as

set forth therein, to serve in such positions effective as of the Closing until successors are duly appointed and qualified in

accordance with applicable Legal Requirements. If any Person designated to serve as a director is unable or unwilling to serve as a

director of Company, as of the Closing, the Party appointing such Person shall designate a successor. Any designated director may

be changed by the Party designating such Person at any time prior to the Closing by written notice to the other Party to include

different board designees who are reasonably acceptable to the other Party.

6.10

Non-Solicitation by Company and Santersus.

(a)

Non-Solicitation by Company.

(i)

Prior to the receipt of Company Stockholder Approval, Company will not, and will not authorize or permit any of its Subsidiaries

or authorize any Representative of any Acquiring Company, directly or indirectly, to (i) solicit or initiate, or knowingly encourage,

induce or facilitate the making, submission or announcement of any Acquisition Proposal or take any action that would reasonably be expected

to lead to an Acquisition Proposal, (ii) furnish any nonpublic information regarding any Acquiring Company to any Person in connection

with or in response to an Acquisition Proposal or an inquiry or indication of interest that would reasonably be expected to lead to an

Acquisition Proposal, (iii) engage in discussions or negotiations with any Person with respect to any Acquisition Proposal, (iv) approve,

endorse or recommend any Acquisition Proposal or (v) enter into any letter of intent or similar document or any agreement providing for

or otherwise relating to any Acquisition Transaction (other than an Acceptable Company Confidentiality Agreement); provided, however,

that prior to obtaining the Company Stockholder Approval, Company may furnish nonpublic information regarding the Acquiring Companies

to, and enter into discussions with, any Person in response to an Acquisition Proposal that, after consultation with its outside legal

and financial advisors, Company’s board of directors determines in good faith is, or is reasonably expected to result in, a Superior

Offer (and is not withdrawn) if (1) such Acquisition Proposal was not the result of a breach of this Section 6.10(a)(i), (2) the

board of directors of Company concludes in good faith, after consultation with its outside legal counsel, that a failure to take such

action is reasonably likely to constitute a breach of the fiduciary duties of the board of directors of Company to the Company Stockholders

under applicable Legal Requirements, (3) prior to furnishing any such information to, or entering into discussions with, such Person,

Company gives Santersus written notice of the identity of such Person and of Company’s intention to furnish information to, or enter

into discussions with, such Person, and Company receives from such Person an executed confidentiality agreement on terms no less favorable

to Company than the confidentiality agreement between Santersus and Company and containing customary limitations on the use and disclosure

of all nonpublic written and oral information furnished to such Person by or on behalf of Company (an “Acceptable Company

Confidentiality Agreement”) and (4) prior to or simultaneously with furnishing any such information to such Person, Company

furnishes or makes available such nonpublic information to Santersus (to the extent such nonpublic information has not been previously

furnished or made available by Company to Santersus). Company shall, and shall cause its Subsidiaries and instruct its and their respective

Representatives to, promptly upon the execution of this Agreement cause to be terminated any solicitation, encouragement, discussion or

negotiation with or involving any Person (other than Santersus, Sellers and their respective Affiliates) conducted heretofore by Company

or any Subsidiary thereof or any of its or their respective Representatives, with respect to an Acquisition Proposal or which could reasonably

be expected to lead to an Acquisition Proposal, and, in connection therewith, Company will immediately discontinue access by any Person

(other than Santersus, Sellers and their respective Affiliates) to any data room (virtual or otherwise) established by Company or its

Representatives for such purpose. Without limiting the generality of the foregoing, Company acknowledges and agrees that in the event

any Representative of Company (or its Subsidiaries) takes any action at the direction of, with the authorization of or with the knowing

permission of Company or any of its Subsidiaries that, if taken by Company (or its Subsidiaries), would constitute a breach of this Section

6.10(a)(i), the taking of such action by such Representative will be deemed to constitute a breach of this Section 6.10(a)(i)

by Company for purposes of this Agreement.

(ii)

Prior to receipt of Company Stockholder Approval, Company will promptly (and in no event later than forty-eight (48) hours after

receipt of any Acquisition Proposal or any inquiry or indication of interest that Company reasonably expects to lead to an Acquisition

Proposal) advise Santersus orally and in writing of any Acquisition Proposal or inquiry or indication of interest that Company reasonably

expects to lead to an Acquisition Proposal (including the identity of the Person making or submitting such Acquisition Proposal, inquiry

or indication of interest, and the material terms thereof) that is made or submitted by any Person during the Pre-Closing Period. Company

will keep Santersus informed, on a prompt basis, in all material respects with respect to the status of any such Acquisition Proposal,

inquiry or indication of interest and any modification or proposed modification thereto.

(b)

Non-Solicitation by Santersus.

(i)

Prior to the receipt of Company Stockholder Approval, neither any Seller nor Santersus will and Santersus will not authorize or

permit any of its Subsidiaries or authorize any Representative of any Santersus Company, directly or indirectly, to (v) solicit or initiate,

or knowingly encourage, induce or facilitate the making, submission or announcement of any Santersus Acquisition Proposal or take any

action that would reasonably be expected to lead to a Santersus Acquisition Proposal, (w) furnish any nonpublic information regarding

any Santersus Company to any Person in connection with or in response to a Santersus Acquisition Proposal or an inquiry or indication

of interest that would reasonably be expected to lead to a Santersus Acquisition Proposal, (x) engage in discussions or negotiations with

any Person with respect to any Santersus Acquisition Proposal, (y) approve, endorse or recommend any Santersus Acquisition Proposal or

(z) enter into any letter of intent or similar document or any agreement providing for or otherwise relating to any transaction described

in the definition of “Santersus Acquisition Proposal”, taking into account the proviso in such definition. Each Seller and

Santersus shall, and Santersus shall cause its Subsidiaries and instruct its and their respective Representatives to, promptly upon the

execution of this Agreement cause to be terminated any solicitation, encouragement, discussion or negotiation with or involving any Person

(other than Company and its respective Affiliates) conducted heretofore by any Seller, Santersus or any Subsidiary thereof or any of its

or their respective Representatives, with respect to a Santersus Acquisition Proposal or which could reasonably be expected to lead to

a Santersus Acquisition Proposal, and, in connection therewith, Santersus will immediately discontinue access by any Person (other than

Company and its respective Affiliates) to any data room (virtual or otherwise) established by Santersus or its Representatives for such

purpose. Without limiting the generality of the foregoing, Santersus acknowledges and agrees that in the event any Representative of Santersus

(or its Subsidiaries), takes any action that, if taken by Santersus (or its Subsidiaries) would constitute a breach of this Section

6.10(b)(i), the taking of such action by such Representative will be deemed to constitute a breach of this Section 6.10(b)(i)

by Santersus for purposes of this Agreement.

(ii)

Prior to the receipt of Company Stockholder Approval, Santersus will promptly (and in no event later than forty-eight (48) hours

after receipt of any Santersus Acquisition Proposal or any inquiry or indication of interest that Santersus reasonably expects to lead

to a Santersus Acquisition Proposal) advise Company orally and in writing of any Santersus Acquisition Proposal or inquiry or indication

of interest that Santersus reasonably expects to lead to a Santersus Acquisition Proposal (including the identity of the Person making

or submitting such Santersus Acquisition Proposal, inquiry or indication of interest, and the material terms thereof) that is made or

submitted by any Person during the Pre-Closing Period. Santersus will keep Company informed, on a prompt basis, in all material respects

with respect to the status of any such Santersus Acquisition Proposal, inquiry or indication of interest and any modification or proposed

modification thereto.

6.11

Restrictions on Transfer.

(a)

Each Seller covenants and agrees for the benefit of Company that during the Pre-Closing Period, other than as set forth on Part

6.11 of the Santersus Disclosure Schedules, such Seller will not, directly or indirectly:

(i)

offer, sell, transfer (whether by merger, operation of law or otherwise), pledge, hypothecate, encumber, assign, tender or otherwise

dispose of, or enter into any contract, option or other arrangement or understanding, directly or indirectly, with respect to the sale,

transfer, pledge, hypothecation, encumbrance, assignment, tender or other disposition of any Santersus Shares, any security convertible

into or exercisable or exchangeable for, or that represents the right to receive, Santersus Shares, or any interest in any of the foregoing;

(ii)

take any other action with respect to Santersus Shares, any security convertible into or exercisable or exchangeable for, or that

represents the right to receive, Santersus Shares, or any interest in any of the foregoing, that would in any way restrict, limit, or

interfere with the performance of such Seller’s obligations hereunder or the Contemplated Transactions.

(b)

Notwithstanding the foregoing, any Seller may assign or transfer Santersus Shares or any other security convertible into or exercisable

or exchangeable for, or that represents the right to receive, Santersus Shares, or any interest in any of the foregoing, to any Permitted

Transferee, provided, however, that (i) such assignment or transfer is made in accordance with applicable Legal Requirements

and in compliance with any contractual restriction upon the assignment or transfer of such shares, securities or interests, including,

where applicable, restrictions contained in the Organizational Documents of Santersus, (ii) such Permitted Transferee has first executed

a Joinder Agreement substantially in the form attached hereto as Exhibit E (“Joinder Agreement”)

and (iii) if the Seller effecting the assignment or transfer is subject to a Santersus Lock-Up Agreement, such Permitted Transferee has

executed and delivered to Company a Santersus Lock-Up Agreement with respect to the shares, securities or interests assigned or transferred

to it. “Permitted Transferee” shall mean any of the following: (i) any Affiliate of such Seller; (ii) any Person

acquiring Santersus Shares from such Seller pursuant to the transactions contemplated by the Norcliffe Agreement (which Persons, for the

avoidance of doubt, have executed this Agreement on the date hereof as “Sellers”), (iii) if such Seller is a natural person,

such Seller’s spouse, Domestic Partner, children, parents, siblings or any other member such Seller’s immediate family, or

to a trust or other estate planning vehicle established for the exclusive benefit of such Seller and/or such Seller’s spouse, children,

parents, siblings or any other member such Seller’s immediate family and (iv) any Person to whom the Company has given its prior

written consent (not to be unreasonably withheld, conditioned or delayed).

6.12

Joinder Agreements. In furtherance and not in limitation of any of the provisions of this Agreement, Santersus shall

cause each Person who is not already a Party and who acquires Santersus Shares from Santersus subsequent to the date hereof, including

through the Santersus Share Conversion or the exercise of any Santersus Options, to become a Party by executing a Joinder Agreement.

6.13

Listing; Symbol. Company shall use its commercially reasonable efforts, (a) to maintain its existing listing on Nasdaq

until the Closing Date and to obtain approval of the listing of the combined company on Nasdaq; (b) without derogating from the generality

of the requirements of the foregoing clause (a) and to the extent required by the rules and regulations of Nasdaq, (i) to prepare

and submit to Nasdaq a notification form for the listing of the shares of Company Common Stock to be issued in connection with the Acquisition,

and (ii) to cause such shares to be approved for listing (subject to official notice of issuance); and (c) to the extent required

by Nasdaq Marketplace Rule 5110, to file an initial listing application for Company Common Stock on Nasdaq (the “Nasdaq Listing

Application”) and to cause such Nasdaq Listing Application to be conditionally approved prior to the Closing. The Parties

will use commercially reasonable efforts to coordinate with respect to compliance with Nasdaq rules and regulations. Santersus will cooperate

with Company as reasonably requested by Company with respect to Nasdaq Listing Application and promptly furnish to Company all information

concerning the Santersus and its stockholders that may be required or reasonably requested in connection with any action contemplated

by this Section 6.13.

6.14

Section 16 Compliance. Subject to the following sentence, prior to the Closing, Company will take all such steps as

may be required (to the extent permitted under applicable Legal Requirements and no-action letters issued by the SEC) to cause any acquisition

of Company Common Stock (including derivative securities with respect to Company Common Stock) pursuant to this Agreement by each individual

who is or will be subject to the reporting requirements of Section 16(a) of the Exchange Act with respect to Company, to be exempt under

Rule 16b-3 under the Exchange Act. At least thirty (30) days prior to the Closing Date, Santersus will furnish the following information

to Company for each individual who, immediately after the Closing, is reasonably expected to become subject to the reporting requirements

of Section 16(a) of the Exchange Act with respect to Company: (a) the number of Santersus Ordinary Shares expected to be held by such

individual immediately following the Santersus Share Conversion and exchanged for shares of Company Common Stock pursuant to the Acquisition;

(b) the number of other derivative securities (if any) with respect to Santersus Shares held by such individual and expected to be converted

into shares of Company Common Stock or derivative securities with respect to Company Common Stock in connection with the Acquisition;

and (c) CCC and CIK codes for purposes of submitting SEC Section 16 filings.

6.15

Santersus Options/ Option Plan.

(a)

At the Closing, each Santersus Option that is outstanding and unexercised immediately prior to the Closing under the Santersus

Option Plan or otherwise, whether or not vested, shall be converted into and become an option to purchase Company Common Stock, and Company

shall assume each such Santersus Option in accordance with their terms (as in effect as of the date of the Agreement) of the Santersus

Option Plan and the terms of the stock option agreement by which such Santersus Option is evidenced. All rights with respect to shares

in the capital of Santersus under Santersus Options assumed by Company shall thereupon be converted into rights with respect to Company

Common Stock. Accordingly from and after the Closing, each Santersus Option shall become an option to purchase a number of shares of Company

Common Stock, determined by multiplying (i) the number of shares of Santersus Ordinary Shares that were subject to such Santersus Option,

as in effect immediately prior to the Closing, by (ii) the Exchange Ratio, and rounding the resulting number down to the nearest whole

number of shares of Company Common Stock; at an exercise price per share determined by dividing (A) the per share exercise price of Santersus

Ordinary Shares subject to such Santersus Option, as in effect immediately prior to the Closing, by (B) the Exchange Ratio and rounding

the resulting exercise price up to the nearest whole cent; provided, however, that such conversion shall in all events occur

in a manner satisfying the requirements of Sections 409A, 422 and 424 of the Code and Treasury Regulation Section 1.424-1. Except as specifically

provided in this Section 6.15, following the Closing, each Santersus Option shall, if applicable, continue to be governed by the

same terms and conditions as set forth in the Santersus Option Plan and any agreement thereunder as were applicable immediately prior

to the Closing, and such Santersus Options shall be subject to adjustment as appropriate to reflect any stock split, division, or subdivision

of shares, stock dividend, reverse stock split, consolidation of shares, reclassification, recapitalization or other similar transaction

with respect to Company Common Stock subsequent to the Closing. In addition to the foregoing, Company shall assume the Santersus Option

Plan (solely with respect to the Santersus Options), and the number and kind of shares available for issuance under the Santersus Option

Plan shall be converted into shares of Company Common Stock in accordance with the adjustment provisions of the Santersus Option Plan.

(b)

Company shall file with the SEC promptly, but no later than thirty (30) calendar days, after the Closing, a registration statement

on Form S-8 (or any successor form), if available for use by Company, relating to the shares of Company Common Stock that are issuable

with respect to Santersus Options assumed by Company in accordance with Section 6.15(a).

(c)

Prior to the Closing, Santersus shall not permit the exercise of any Santersus Option unless the holder of such Santersus Option

has executed a Joinder Agreement.

(d)

Prior to the Closing, each of Company and Santersus shall take all action necessary (under the Santersus Option Plan and otherwise)

to assume the Santersus Option Plan by Company and effectuate the provisions of this Section 6.15. Santersus shall ensure that,

as of the Closing, no holder of a Santersus Option (or former holder of any such equity awards) or a participant in a Santersus Option

Plan shall have any rights thereunder to acquire, or other rights in respect of, the capital stock of Santersus or any of its Subsidiaries,

or any other equity interest therein (including “phantom” stock or stock appreciation rights). As soon as practicable following

the date of this Agreement, Santersus shall deliver written notice to each holder of a Santersus Option, to the extent applicable, informing

such holder of the effect of the transactions contemplated by this Agreement on the Santersus Options.

6.16

Allocation Certificate.

(a)

Santersus will prepare and deliver to Company no later than two (2) Business Days following the final determination of Company

Net Cash at the Anticipated Closing Date in accordance with Section 1.5, and at least two (2) Business Days prior to the Closing

Date, a certificate signed by a duly authorized officer of Santersus in a form reasonably acceptable to Company which sets forth a true

and complete list of Sellers immediately prior to the Closing and the number Santersus Shares owned by each such Seller after giving effect

to the Santersus Share Conversion, the Norcliffe Transfer and the allocation of the Acquisition Consideration among Sellers pursuant to

the Acquisition (the “Santersus Allocation Certificate”).

(b)

Company will prepare and deliver to Santersus no later than two (2) Business Days following the final determination of Company

Net Cash at the Anticipated Closing Date in accordance with Section 1.5, and at least two (2) Business Days prior to the Closing

Date, a certificate signed by a duly authorized officer of Company in a form reasonably acceptable to Santersus which sets forth, as of

immediately prior to the Closing: (i) each record holder of Company Common Stock, Company Warrants, Company Options or Company Restricted

Stock, and (ii) the number of shares of Company Common Stock (on an as converted basis with respect to any Company Preferred Stock)

held and/or underlying the Company Warrants, Company Options or Company Restricted Stock as of the Closing for such holder (the “Company

Outstanding Shares Certificate”).

6.17

Employee Matters. No provision of this Agreement shall (a) create any right in any current or former employee or other

service provider of Santersus, Company or any of their respective Subsidiaries to continued employment or service or, subject to the terms

of any applicable employment, consulting or other agreement, preclude the ability of Santersus, Company or any of their respective Subsidiaries

to terminate the employment or service of any employee or service provider for any reason, (b) require Santersus, Company or any of their

respective Subsidiaries to continue any Company Employee Plan or Santersus Employee Plan or prevent the amendment, modification or termination

thereof, (c) confer upon any current or former employee or other service provider of Santersus, Company or any of their respective Subsidiaries,

or any beneficiaries or dependents thereof, any rights or remedies under or by reason of this Agreement or (d) be treated as an amendment

to any Company Employee Plan or Santersus Employee Plan.

6.18

Disclosure Schedules. Each of Company and Santersus may in its discretion, for informational purposes only, supplement

the information set forth on the Company Disclosure Schedule or Santersus Disclosure Schedule, as applicable, with respect to any matter

now existing or hereafter arising that, if existing or occurring at or prior to the date hereof, would have been required to be set forth

or described in the Company Disclosure Schedule or Santersus Disclosure Schedule, as applicable, on the date hereof or that is necessary

to correct any information in the Company Disclosure Schedule or Santersus Disclosure Schedule, as applicable, which has been rendered

inaccurate thereby promptly following discovery thereof. Prior to the Closing, (x) Santersus shall supplement Part 2.2 of the Santersus

Disclosure Schedule and Part 4.1 of the Santersus Disclosure Schedule to reflect (A) the addition of Permitted Transferees as “Sellers”

hereunder and (B) the Santersus Share Conversion and the issuance of Santersus Ordinary Shares pursuant to the exercise of Santersus Options

in accordance with the terms under the Santersus Option Plan and (y) Company may supplement Part 3.2 of the Company Disclosure

Schedule to reflect (A) the issuance of shares of Company Common Stock pursuant to the exercise of Company Options or Company Warrants

in accordance with their terms and (B) any other changes to the capitalization of Company that are permitted under this Agreement. Except

as provided in the two preceding sentences, any amended or supplemented disclosure shall not be deemed to modify the representations and

warranties of Company, Santersus or Sellers for purposes of Section 7.2(a) and 7.3(a) or any other provision of this Agreement.

6.19

Tax Matters. For U.S. federal income Tax purposes, the Parties intend that the Acquisition shall constitute a tax-free

reorganization within the meaning of Section 368(a) of the Code. The Parties shall use their commercially reasonable efforts, and shall

cause their respective Affiliates to use their commercially reasonable efforts, to take or cause to be taken any action necessary for

the Acquisition to qualify as a reorganization within the meaning of Section 368(a) of the Code and no Party shall take any position on

any Tax Return that is inconsistent with such treatment unless otherwise required pursuant to a “determination” within the

meaning of Section 1313(a) of the Code. None of the Parties makes any representation regarding whether the Acquisition will so qualify.

The Parties acknowledge that each Party is relying solely on its own Tax advisors in connection with this Agreement, the Acquisition,

and the other transactions and agreements contemplated hereby. This Agreement is intended to constitute, and the parties hereto hereby

adopt this Agreement as, a “plan of reorganization” within the meaning of Treasury Regulation Section 1.368-2(g) and 1.368-3(a).

Notwithstanding anything herein to the contrary in this Agreement, no Party shall take, or omit to take, any action that could reasonably

be expected to prevent or impede the Acquisition from qualifying as a reorganization within the meaning of Section 368(a) of the Code,

and the Company shall not pay, deliver or cause to be paid or delivered to any Seller any consideration other than shares of Company Common

Stock.

6.20

Reverse Stock Split. Prior to the Closing, if the Company or Santersus reasonably believes that the closing bid price

of Company Common Stock is reasonably likely to fail, or has failed, to satisfy the minimum bid price requirement for initial listing

on the Nasdaq Capital Market (as set forth in Nasdaq Listing Rule 5505(a)(1) or any successor rule) or the minimum bid price requirement

for continued listing on Nasdaq Capital Market (as set forth in Nasdaq Listing Rule 5550(a) or any successor rule), or if Nasdaq advises

Company or Santersus in writing that either such requirement is not satisfied, the Company or Santersus, as applicable, shall deliver

written notice to the other party, and the Company, as promptly as practicable, shall effect a reverse stock split of Company Common Stock

at an exchange ratio within a range to be determined by Company in consultation with Santersus to cause the post-split closing bid price

to satisfy the applicable Nasdaq minimum bid price requirement.

6.21

Stockholder Litigation. During the Pre-Closing Period, Company shall (a) advise Santersus in writing of any stockholder

litigation against it or its directors relating to this Agreement or the Contemplated Transactions promptly after becoming aware of any

such litigation and shall keep Santersus reasonably apprised regarding developments in such stockholder litigation and (b) give Santersus

the opportunity to participate in (but not control) the defense or settlement of any stockholder litigation relating to this Agreement

or any of the Contemplated Transactions in accordance with the terms of a mutually agreed upon joint defense agreement, and shall not

settle any such litigation without Santersus’ prior written consent (such consent shall not to be unreasonably withheld, delayed

or conditioned); provided, however, that such consent shall not be required for settlements solely for (i) money damages and the payment

of attorneys’ fees in an aggregate amount not in excess of the dollar amount of the coverage limits for such settlements under the

current policies of insurance maintained by the Acquiring Companies or (ii) providing additional disclosure in the Proxy Statement.

6.22

Termination of Contracts(a). Santersus and Sellers shall use commercially reasonable efforts to reasonably promptly

after the date hereof terminate all Contracts listed on Schedule 6.22 and fully satisfy, waive or otherwise discharge all obligations

of Sellers, Santersus and its Subsidiaries (as applicable) under such Contracts, in each case prior to Closing.

6.23

No Trading(a). Santersus and the Sellers each acknowledge and agree that it is aware, and that their respective Affiliates

are aware (and each of their respective Representatives is aware or, upon receipt of any material nonpublic information of Company, will

be advised) of the restrictions imposed by U.S. federal securities Legal Requirements and the rules and regulations of the SEC and Nasdaq

promulgated thereunder or otherwise (the “Federal Securities Laws”) and other applicable foreign and domestic

Legal Requirements on a Person possessing material nonpublic information about a publicly traded company. The Santersus Companies, the

Sellers and their respective Representatives each hereby agree that, during any time prior to the Closing, and while it is in possession

of such material nonpublic information, it shall not, directly or indirectly, (other than with respect to the Contemplated Transactions)

(i) purchase or sell any securities of Company, (ii) communicate such information to any third party, (iii) make, engage in or participate

in any “solicitation” of “proxies” (as such terms are used for purposes of Section 14(a) of the Exchange Act)

or consents or undertakings to vote any securities of the Company (whether or not related to the election or removal of directors), or

otherwise seek to influence or control, in any manner whatsoever, the voting of any securities of the Company, (iv) form, join or in any

way participate in a “group” as defined in Section 13(d)(3) of the Exchange Act or (v) take any other action with respect

to Company in violation of such Legal Requirements, or cause or encourage any third party to do any of the foregoing.

6.24

Continuation of the Business. Following the Closing Date until the first anniversary of the Closing Date, Company shall,

and shall cause its Subsidiaries to, use commercially reasonable efforts to continue the development and advancement of the DNase technology

which is designed to improve outcomes of existing treatments, including immunotherapies and oncology treatments, by targeting neutrophil

extracellular traps, which are involved in cancer growth, metastasis and progression, and contribute to immunotherapy, chemotherapy and

radiotherapy resistance (the “Protected Program”), and shall not terminate or abandon the Protected Program;

provided, however, that the foregoing obligations shall not apply to the extent that the continuation of the Protected Program

is prohibited or materially restricted by any Governmental Body or applicable Legal Requirement.

Article

CONDITIONS TO THE CLOSING

7.1

Conditions to Obligation of Each Party to Effect the Acquisition. The respective obligations of each Party to effect

the Acquisition will be subject to the satisfaction (or written waiver by Company and Santersus), if permissible under applicable Legal

Requirements) at or prior to the Closing of the following conditions:

(a)

No Injunctions or Restraints; Illegality. No temporary restraining order, preliminary or permanent injunction or other order

preventing the consummation of the Acquisition shall have been issued by any court of competent jurisdiction and remain in effect; and

there will not be any statute, rule, regulation or order enacted, entered, enforced or deemed applicable to the Acquisition, which makes

the consummation of the Acquisition illegal.

(b)

Stockholder Approval. The Company Stockholder Approval Matters will have been duly approved by the Company Stockholder Approval

Threshold.

(c)

Effective Registration Statement. The Registration Statement shall have become effective and no stop order suspending the

effectiveness of the Registration Statement shall have been issued and no proceedings for that purpose shall have been initiated by the

SEC and not withdrawn.

(d)

Listing; Symbol. The shares of Company Common Stock to be issued in connection with the Acquisition shall be approved for

listing on Nasdaq, subject to consummation of the Contemplated Transactions and official notice of issuance.

(e)

Net Cash. Net Cash shall have been finally determined in accordance with Section 1.5.

7.2

Additional Conditions to Obligations of Santersus and Sellers. The obligation of Santersus and Sellers to effect the

Acquisition is also subject to the satisfaction or waiver by Santersus, at or prior to Closing, of the following conditions:

(a)

Representations and Warranties. (i) The representations and warranties of Company contained in Section 3.1(b) (Organization

and Qualification; Charter Documents), Sections 3.3(a), 3.3(b), 3.3(c)(i) and 3.3(c)(ii) (Authority; Non-Contravention;

Approvals) shall have been true and correct in all material respects at and as of the date of this Agreement and shall be true and correct

in all material respects at and as of the Closing Date with the same force and effect as if made at and as of such date, except to the

extent that such representations and warranties refer specifically to an earlier date, in which case such representations and warranties

shall have been true and correct in all material respects as of such earlier date; (ii) the representations and warranties of Company

contained in Sections 3.2 (Capital Structure) and 3.12 (Brokers’ and Finders’ Fees) shall have been true and

correct in all respects (other than de minimis inaccuracies) at and as of the date of this Agreement and shall be true and correct

(other than de minimis inaccuracies) in all respects on and as of the Closing Date (after giving effect to any supplements to Part

3.2 of the Company Disclosure Schedule, as applicable); and (iii) the other representations and warranties of Company contained in this

Agreement or in any certificate or other agreement delivered by Company pursuant hereto shall be true and correct at and as of the date

hereof and as of the Closing with the same force and effect as if made on and as of such date (or, in the case of those representations

and warranties that are made as of a particular date or period, as of such date or period), except, in the case of clause (iii), where

the failure of such representations and warranties to be true and correct (disregarding all qualifications or limitations as to “materially,”

“Company Material Adverse Effect” and words of similar import set forth therein) has not had, individually or in the aggregate,

a Company Material Adverse Effect (it being understood that, except as set forth herein, for purposes of determining the accuracy of such

representations and warranties, any update of or modification to the Company Disclosure Schedule made or purported to have been made after

the date of this Agreement shall be disregarded).

(b)

Agreements and Covenants. Company will have performed or complied with in all material respects all agreements and covenants

required by this Agreement to be performed or complied with by it on or prior to the Closing.

(c)

Company Material Adverse Effect. Since the date hereof no Company Material Adverse Effect shall have occurred and be continuing.

(d) Other Deliveries.

Santersus will have received (i) a certificate executed by a duly authorized officer of Company confirming that the conditions set forth

in Sections 7.2(a), 7.2(b), and 7.2(c) have been duly satisfied and (ii) the Company Outstanding Shares Certificate.

(e)

Company Officers and Board of Directors. Santersus will have received a duly executed copy of a resignation letter from

each of the Resigning Company Board Members and the Resigning Company Officers, pursuant to which each such person will resign as a member

of the board of directors of Company (and its Subsidiaries) and/or as an officer of Company (and its Subsidiaries), as applicable, effective

as of the Closing.

(f)

Company Lock-Up Agreements. The Company Lock-Up Agreements shall be in full force and effect and shall continue to be in

full force and effect immediately following the Closing.

(g)

Suspension of Trading or Listing. No delisting or suspension of trading of Company Common Stock on Nasdaq shall have occurred

and be continuing.

7.3

Additional Conditions to Obligations of Company. The obligation of Company to effect the Acquisition is also subject

to the following conditions:

(a)

Representations and Warranties. (i) The representations and warranties of Santersus contained in Section 2.1 (Organization

and Qualification; Charter Documents), Sections 2.3(a), 2.3(b)(i), and 2.3(b)(ii) (Authority; Non-Contravention;

Approvals), and Section 2.22 (Ownership of Company Common Stock) and the representations and warranties of Sellers contained in

Section 4.2 (Authority; Non-Contravention) shall have been true and correct in all material respects at and as of the date of this

Agreement and shall be true and correct in all material respects at and as of the Closing Date with the same force and effect as if made

at and as of such date, except to the extent that such representations and warranties refer specifically to an earlier date, in which

case such representations and warranties shall have been true and correct in all material respects as of such earlier date; (ii) the representations

and warranties of Santersus contained in Section 2.2 (Capital Structure) and Section 2.12 (Brokers’ and Finders’

Fees) and the representations and warranties of Sellers contained in Section 4.1 (Ownership of Santersus Share Capital) shall have

been true and correct (other than de minimis inaccuracies) in all respects at and as of the date of this Agreement and shall have

been true and correct (other than de minimis inaccuracies) in all respects at and as of the Closing Date (after giving effect to

any supplements to Part 2.2 and Part 4.1 of the Santersus Disclosure Schedule, as applicable); and (iii) the other representations

and warranties of Santersus and Sellers contained in this Agreement or in any certificate or other agreement delivered by Santersus or

Sellers, as applicable, pursuant hereto shall have been true and correct in all respects at and as of the date hereof and shall be true

and correct in all respects on and as of the Closing with the same force and effect as if made on and as of such date (or, in the case

of those representations and warranties that are made as of a particular date or period, as of such date or period), except, in the case

of clause (iii), where the failure of such representations and warranties to be true and correct (disregarding all qualifications or limitations

as to “materially,” “Santersus Material Adverse Effect” and words of similar import set forth therein) has not

had, individually or in the aggregate, a Santersus Material Adverse Effect (it being understood that, except as set forth herein, for

purposes of determining the accuracy of such representations and warranties, any update of or modification to the Santersus Disclosure

Schedule made or purported to have been made after the date of this Agreement shall be disregarded).

(b)

Agreements and Covenants. Santersus and Sellers will have performed or complied with in all material respects all agreements

and covenants required by this Agreement to be performed or complied with by them on or prior to the Closing.

(c)

Santersus Material Adverse Effect. Since the date hereof no Santersus Material Adverse Effect shall have occurred and be

continuing.

(d)

Other Deliveries.

(i)

Company will have received a certified commercial-register extract (or equivalent documentation) of the Santersus Companies (other

than Santersus) and a certificate executed by a duly authorized director of Santersus confirming that the conditions set forth in Sections

7.3(a), 7.3(b) and 7.3(c) have been duly satisfied.

(ii)

Sellers shall have delivered to the Exchange Agent the Share Assignment Declarations, executed in wet-ink by each Seller with respect

to his/her/its Santersus Shares, in original;

(iii)

a unanimous resolution of the board of directors of Santersus, approving the transfer of the Santersus Shares to the Company and

the registration of the Company as shareholder of the Santersus Shares with full voting rights in the share register of Santersus, executed

in wet-ink by all members of the board of directors of Santersus, in original;

(iv)

the share register and register of beneficial owners of Santersus, evidencing the Company's ownership of the Santersus Shares with

full voting rights, and the beneficial owner of the Company in accordance with article 697l paragraph 2 of the Swiss Code of Obligations,

executed by any member of the board of director of Santersus, in original;

(v)

a certified copy of the commercial registry extract of Santersus, showing the completion and registration of the Santersus Share

Conversion;

(vi)

a certified copy of the Santersus A&R Articles of Incorporation, as adopted by the general assembly of the shareholders of

Santersus; and

(vii)

Sellers shall have delivered to the Exchange Agent or Company such other waivers, consents or transfer forms as may be necessary

to enable Company or its nominee(s) to become the registered holder of all of the Santersus Shares.

(e)

Allocation Certificate. A duly authorized officer of Santersus will have executed and delivered to Company the Santersus

Allocation Certificate.

(f)

Santersus Lock-Up Agreements. The Santersus Lock-Up Agreements shall be in full force and effect and shall continue to be

in full force and effect immediately following the Closing.

(g)

Termination of Santersus Contracts. The Contracts set forth on Schedule 6.22 shall have been terminated (or such

termination shall have been made effective upon the occurrence of the Closing).

(h)

Conversion. The Santersus Share Conversion shall have occurred.

(i)

Seller Joinders. All holders of Santersus Issued Share Capital shall have executed this Agreement or a Joinder Agreement.

7.4

Frustration of Closing Conditions. No party hereto may rely on the failure of any condition set forth in Section

7.1, Section 7.2 or Section 7.3, as the case may be, if such failure was caused by such party’s failure to comply

with any provision of this Agreement.

Article

TERMINATION

8.1

Termination. This Agreement may be terminated and the Acquisition may be abandoned, at any time prior to the Closing,

notwithstanding approval thereof by the Company Stockholders unless otherwise specified below:

(a)

by mutual written consent of Company and Santersus;

(b)

by either Santersus or Company, after the End Date, if the Acquisition has not been consummated; provided that the right

to terminate this Agreement under this Section 8.1(b) will not be available to any Party whose failure to fulfill any obligation

under this Agreement has been the cause of or resulted in the failure of the Acquisition to occur on or before such date; provided,

further, that the End Date shall be subject to extension to the extent required to permit compliance with the provisions of Section

1.5, including the final determination of Net Cash thereunder; and provided, further, that, in the event that the SEC

has not declared effective under the Securities Act the Registration Statement by the End Date, each of Company and Santersus shall be

entitled to extend the period for termination of this Agreement pursuant to this Section 8.1(b) for an additional sixty (60) days,

and such date, as extended, shall be the “End Date”;

(c)

by either Santersus or Company if a Governmental Body in the United States or Switzerland has issued a non-appealable final order,

decree or ruling or taken any other action, in each case having the effect of permanently restraining, enjoining or otherwise prohibiting

the Acquisition (provided that the right to terminate this Agreement under this Section 8.1(c) will not be available to

any Party whose failure to fulfill any obligation under this Agreement has been the cause of such order, decree or ruling or other action);

(d)

by either Santersus or Company if the Company Stockholders’ Meeting (including any adjournments and postponements thereof)

shall have been held and completed and the Company Stockholders shall have taken a final vote on the Company Stockholder Approval and

the Company Stockholder Approval shall not have been obtained; provided, however, that the right to terminate this Agreement

under this Section 8.1(d) shall not be available to a Party where the failure to obtain the Company Stockholder Approval shall

have been caused by the action or failure to act of such Party and such action or failure to act constitutes a material breach by such

Party of this Agreement;

(e)

by Santersus upon breach of any of the representations, warranties, covenants or agreements on the part of Company set forth in

this Agreement, or if any representation or warranty of Company will have become inaccurate, in either case such that the conditions set

forth in Section 7.2(a) or Section 7.2(b) would not be satisfied as of the time of such breach or as of the time such representation

or warranty will have become inaccurate; provided if such breach or inaccuracy is curable by Company by the End Date, then this

Agreement will not terminate pursuant to this Section 8.1(e) as a result of such particular breach or inaccuracy unless the breach

or inaccuracy remains uncured as of the thirtieth (30th) day following the date of written notice given by Santersus to Company of such

breach or inaccuracy and its intention to terminate this Agreement pursuant to this Section 8.1(e); provided further

that no termination may be made pursuant to this Section 8.1(e) solely as a result of the failure of Company to obtain the Company

Stockholder Approval (in which case such termination must be made pursuant to Section 8.1(d));

(f)

by Company upon breach of any of the representations, warranties, covenants or agreements on the part of Santersus or Sellers set

forth in this Agreement, or if any representation or warranty of Santersus or Sellers will have become inaccurate, in either case such

that the conditions set forth in Section 7.3(a) or Section 7.3(b) would not be satisfied as of the time of such breach or

as of the time such representation or warranty will have become inaccurate; provided if such breach or inaccuracy is curable by

Santersus or Sellers by the End Date, as applicable, then this Agreement will not terminate pursuant to this Section 8.1(f) as

a result of such particular breach or inaccuracy unless the breach or inaccuracy remains uncured as of the thirtieth (30th) day following

the date of written notice given by Company to Santersus of such breach or inaccuracy and its intention to terminate this Agreement pursuant

to this Section 8.1(f);

(g)

by Santersus, prior to obtaining the Company Stockholder Approval, if (i) the board of directors of Company has failed to include

the Company Board Recommendation in the Proxy Statement or effected any Company Change in Recommendation; (ii) following the public disclosure

of an Acquisition Proposal (other than a tender or exchange offer which is the subject of clause (iv)), the board of directors of Company

has failed to publicly reaffirm the Company Board Recommendation within five (5) Business Days after Santersus so requests in writing

pursuant to Section 6.2(b); (iii) Company has entered into any letter of intent or definitive agreement relating to any Acquisition

Proposal (other than a confidentiality agreement permitted pursuant to Section 6.10(a)(i)); (iv) the Company, any Related Party

Director or any officer of the Company shall have committed a Willful Breach of Section 6.2 or Section 6.10(a)(i); or (v)

the Company fails to recommend against any Acquisition Proposal that is a tender or exchange offer by a third party pursuant to Rule 14d-9 or

Rule 14e-2 promulgated under the Exchange Act; or

(h)

by Company, prior to obtaining the Company Stockholder Approval, if (i) Company has received a Superior Offer, (ii) Company has

complied in all material respects with its obligations under Section 6.2(c) in order to accept such Superior Offer, (iii) Company

concurrently terminates this Agreement and enters into a definitive agreement with respect to such Superior Offer and (iv) Company pays

to Santersus the Company Termination Fee in accordance with Section 8.3(b) concurrently with, and as a condition to the effectiveness,

of such termination.

8.2

Effect of Termination. In the event of the termination of this Agreement pursuant to Section 8.1, written notice

shall be provided by the Party terminating this Agreement, which notice shall refer to the provision hereof pursuant to which the termination

is made, and this Agreement will forthwith become void and there will be no Liability on the part of any Party or any of its Affiliates,

directors, officers or stockholders except as set forth in Sections 8.2 and 8.3. No termination of this Agreement will affect

the obligations of the Parties contained in the Confidentiality Agreement, all of which obligations will, in addition to Section 6.7,

Section 8.2, Section 8.3, Article 9 and the definitions of the defined terms in such Section (including the definitions

of such defined terms set forth in Exhibit A) survive termination of this Agreement in accordance with its terms. For the

avoidance of doubt, the termination of this Agreement and the provisions of Section 8.3 shall not relieve any Party of any liability

for Fraud or Willful Breach of any representation, warranty, covenant, obligation or provision contained in this Agreement.

8.3

Expenses; Termination Fees.

(a)

Except as set forth in this Section 8.3 and Section 1.5, all fees and expenses incurred in connection with this Agreement

and the Contemplated Transactions will be paid by the Party incurring such expenses, whether or not the Acquisition is consummated. Each

of the Parties acknowledges that the agreements contained in this Section 8.3 are an integral part of the Contemplated Transactions,

without which, the Parties would not enter into this Agreement. It is understood and agreed that all fees and expenses incurred or to

be incurred by Company in connection with the Contemplated Transactions and preparing, negotiating and entering into this Agreement and

the performance of its obligations under this Agreement shall be paid by Company in cash at or prior to the Closing, except with respect

to fees and expenses for the D&O Tail and the Nasdaq Listing Application, which shall be paid 50% by Company and 50% by Santersus.

(b)

Company will pay to Santersus a termination fee (the “Company Termination Fee”) in an amount in cash

equal to $500,000 in the event that this Agreement is terminated pursuant to (i) Section 8.1(b), (ii) Section 8.1(d), (iii)

Section 8.1(e), (iv) Section 8.1(g) or (v) Section 8.1(h); provided that, in the case of each of clauses (i),

(ii) and (iii), an Acquisition Proposal has been publicly announced, disclosed or otherwise communicated to Company’s board of directors

after the date hereof and prior to such termination and, within twelve (12) months after the date of such termination, Company entered

into a definitive agreement with respect to, or consummates, such Acquisition Transaction, such fee to be paid not later than two (2)

Business Days after such Acquisition Transaction is consummated; provided that for purposes of this Section 8.3(b) all references

in the definition of Acquisition Transaction to 25% shall instead refer to 50%. If this Agreement is terminated by Santersus pursuant

to Section 8.1(g), then Company shall pay the Company Termination Fee to Santersus within two (2) Business Days following such

termination.

of Company to consummate the transactions to be consummated at the Closing solely as a result of a Company Material Adverse Effect as

set forth in Section 7.2(c) (provided, that at such time all of the other conditions precedent to Company’s

obligation to close set forth in Section 7.1 and Section 7.2 have been satisfied by Company or are

capable of being satisfied by Company by the Closing or have been waived by Santersus), then the Company shall, no later than two (2)

Business Days after receipt of reasonable supporting documentation evidencing such fees and expenses, reimburse Santersus for all fees

expenses (up to $300,000 (such among, the “Expense Reimbursement Cap”) incurred by Santersus in connection

with the authorization, preparation, negotiation, execution and performance of this Agreement and the Contemplated Transactions. In the

event of the failure of Santersus to consummate the transactions to be consummated at the Closing solely as a result of a Santersus Material

Adverse Effect as set forth in Section 7.3(c) (provided, that at such time all of the other conditions precedent

to Santersus’ obligation to close set forth in Section 7.1 and Section 7.3 have been satisfied

by Santersus or are capable of being satisfied by Santersus by the Closing or have been waived by Company), then Santersus shall, no

later than two (2) Business Days after receipt of reasonable supporting documentation evidencing such fees and expenses, reimburse Company

for all fees expenses (up to the Expense Reimbursement Cap) incurred by Company in connection with the authorization, preparation, negotiation,

execution and performance of this Agreement and the Contemplated Transactions. If this Agreement is terminated by Santersus pursuant

to Section 8.1(e), then the Company shall, no later than two (2) Business Days after receipt of reasonable supporting documentation

evidencing such fees and expenses, reimburse Santersus for all fees expenses (up to the Expense Reimbursement Cap) incurred by Santersus

in connection with the authorization, preparation, negotiation, execution and performance of this Agreement and the Contemplated Transaction.

If this Agreement is terminated by the Company pursuant to Section 8.1(f), then Santersus shall, no later than two (2) Business

Days after receipt of reasonable supporting documentation evidencing such fees and expenses, reimburse Company for all fees expenses

(up to the Expense Reimbursement Cap) incurred by Company in connection with the authorization, preparation, negotiation, execution and

performance of this Agreement and the Contemplated Transaction.

(d)

In the event that Santersus shall be entitled to receive the Company Termination Fee, such fee is not a penalty but shall be liquidated

damages in a reasonable amount for any and all losses or damages suffered or incurred by Santersus and Sellers or in connection with the

matter forming the basis for such termination. Notwithstanding any other provision of this Agreement to the contrary, other than as provided

in this Section 8.3 and except in the case of Fraud or Willful Breach, the Parties agree that the payments contemplated by this

Section 8.3 represent the sole and exclusive remedies of Santersus and Sellers in respect of a termination pursuant to Section

8.1 under circumstances requiring the payment of the Company Termination Fee. While Santersus may seek specific performance in accordance

with Section 9.9 and may also seek a payment of the Company Termination Fee under Section 8.3 to the extent such

fee is payable upon termination of this Agreement, under no circumstances shall Santersus be permitted or entitled to receive both (i)

a grant of specific performance that results in the Closing and (ii) any monetary damages, including all or any portion of the Company

Termination Fee or reimbursement amounts pursuant to Section 8.3(c). If Santersus receives full payment of the Company Termination

Fee pursuant to Section 8.3(b), the receipt of the Company Termination Fee shall be the sole and exclusive remedy (whether at law,

in equity, or through a claim by or on behalf of a party or otherwise) of Santersus, the Sellers or any of their Affiliates for any and

all Liabilities as a result of breach of this Agreement or any of the Ancillary Agreements, except in the case of Fraud or Willful Breach

(and except for any breach of the Confidentiality Agreement or any Ancillary Agreement that by its terms survives the termination of this

Agreement). In no event shall Company be required to pay or cause to be paid the Company Termination Fee on more than one occasion. For

the avoidance of doubt, under no circumstances shall Santersus be permitted or entitled to receive both (i) the Company Termination Fee

and (ii) reimbursement of expenses pursuant to Section 8.3(c); provided, that nothing in this Section 8.3(d) shall limit Santersus’

right to recover damages or obtain equitable relief in respect of Fraud or Willful Breach to the extent such damages or relief exceed

the Company Termination Fee or arise from matters other than the termination event giving rise to the Company Termination Fee.

(e)

If Company or Santersus fails to pay the Company Termination Fee or any other amounts payable under this Section 8.3 when

due and such amount is undisputed or has been finally determined by a court of competent jurisdiction to be payable (such party, the “Defaulting

Party”, then (i) the Defaulting Party will reimburse the other Party for all out-of-pocket costs and expenses (including

reasonable and documented fees and disbursements of counsel) incurred in connection with the collection of such overdue amount and the

enforcement by the Parties of their rights under this Section 8.3 and (ii) the Defaulting Party will pay to the other Party interest

on such overdue amount (for the period commencing as of the date such overdue amount was originally required to be paid and ending on

the date such overdue amount is actually paid to the Parties entitled thereto in full) at a rate per annum equal to the “prime rate”

(as announced by Bank of America or any successor thereto) in effect on the date such overdue amount was originally required to be paid.

Article

GENERAL PROVISIONS

9.1

Notices. Any notice or other communication required or permitted to be delivered to any Party under this Agreement will

be in writing and will be deemed properly delivered, given and received: (a) if delivered by hand, when delivered; (b) if sent on a Business

Day by email with confirmed receipt before 5:00 p.m. (recipient’s time) on the date sent, on such Business Day; (c) if sent by email

on a day other than a Business Day, or if sent by email with confirmed receipt at any time after 5:00 p.m. (recipient’s time) on

the date sent, on the date on which receipt is confirmed, if a Business Day, and otherwise on the first Business Day following the date

on which receipt is confirmed; (d) if sent by registered, certified or first class mail, the third Business Day after being sent; and

(e) if sent by overnight delivery via a national courier service, one Business Day after being sent, in each case to the address or email

address set forth beneath the name of such Party below (or to such other address or email address as such Party shall have specified in

a written notice given to the other Parties hereto):

(a)

If to Santersus, Sellers’ Representative or Sellers:

Santersus AG

c/o Lex Futura AG

Nüschelerstrasse 45

6001 Zürich

Switzerland

Attn: Scott Maguire

Email:msm@santersus.com

With a copy (which shall not constitute notice) to:

Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C.

One Financial Center

Boston, MA 02111

Attn.: Eric Foster, William C. Hicks, Matt J. Gardella, Jason S. McCaffrey

Email: EFoster@mintz.com, wchicks@mintz.com; mjgardella@mintz.com;

jsmccaffrey@mintz.com

(b)

If to Company:

Xenetic Biosciences, Inc.

945 Concord Street

Framingham, MA 01701

Attn: James F. Parslow

Email: j.parslow@xeneticbio.com

With a copy (which shall not constitute notice) to:

Holland & Knight LLP

Attn: Danielle Price

Email: Danielle.price@hklaw.com

9.2

Amendment. This Agreement may be amended or waived prior to the Closing if, and only if, such amendment or waiver is

in writing and signed (a) in the case of an amendment, by Company, Santersus and Sellers’ Representative and (b) in the case of

a waiver, by either Company or Santersus and Sellers’ Representative, as applicable; provided further that any

amendment or waiver of the provisions of Section 6.5 after the Closing which adversely affects the D&O Indemnified Parties

must be approved in writing by the D&O Indemnified Parties; and provided further that, after approval of the Acquisition

by the Company Stockholder Approval no amendment may be made which by Legal Requirements requires further approval by such stockholders

without such further approval.

9.3

Headings. The headings contained in this Agreement are for reference purposes only and will not affect in any way the

meaning or interpretation of this Agreement.

9.4

Severability. If any term or other provision of this Agreement is invalid, illegal or incapable of being enforced by

any rule of law, or public policy, all other conditions and provisions of this Agreement will nevertheless remain in full force and effect

so long as the economic or legal substance of the Contemplated Transactions is not affected in any manner adverse to any Party. Upon such

determination that any term or other provision is invalid, illegal or incapable of being enforced, the Parties will negotiate in good

faith to modify this Agreement so as to effect the original intent of the Parties as closely as possible in an acceptable manner to the

end that the Contemplated Transactions are fulfilled to the extent possible.

9.5

Entire Agreement. This Agreement (including the Company Disclosure Schedule and the Santersus Disclosure Schedule) constitutes

the entire agreement between the Parties hereto and supersedes all prior agreements and undertakings (other than the Confidentiality Agreement),

both written and oral, among the Parties, or any of them, with respect to the subject matter hereof.

9.6

Successors and Assigns. This Agreement will be binding upon: (a) Company and its successors and assigns (if any); (b)

Santersus and its successors and assigns (if any); and (c) Sellers and their respective heirs, successors and assigns (if any). This Agreement

will inure to the benefit of: (i) Company; (ii) Santersus; (iii) Sellers; and (iv) the respective heirs, successors and assigns (if any)

of the foregoing. Neither Company nor Santersus may assign this Agreement or any of its rights, interests or obligations hereunder without

the prior written approval of the other, and no Seller may assign this Agreement or any of its rights, interests or obligations hereunder

without the prior written approval of Company and Santersus. Any purported assignment in violation of this Section 9.6 shall be

null and void ab initio.

9.7

Parties in Interest. This Agreement will be binding upon and inure solely to the benefit of each Party, and nothing

in this Agreement, expressed or implied, is intended to or will confer upon any other Person any right, benefit or remedy of any nature

whatsoever under or by reason of this Agreement, other than (i) Section 6.5 (which is intended to be for the benefit of D&O

Indemnified Parties and may be enforced by D&O Indemnified Parties) and (ii) and Company shall, in its sole and absolute discretion

and as the sole and exclusive agent for and on behalf of the stockholders of the Company, have the sole and exclusive authority to take

action on behalf of the stockholders of the Company to enforce the rights of such stockholders under this Agreement, including with respect

to the recovery of damages based on the losses suffered by the stockholders of the Company (including the loss of the economic benefit

of the transactions to the stockholders of the Company); provided that the Company shall (A) be entitled to retain the amount

of any payment received in connection with the enforcement by the Company of such rights and (B) not be liable to the stockholders

of the Company for any action taken, suffered or omitted to be taken by it in good faith except to the extent that the Company’s

gross negligence or willful misconduct was the cause of any direct loss to the stockholders of the Company. Notwithstanding the foregoing,

for the avoidance of doubt, Company shall have the right to enforce this Agreement directly against any Seller in the event of a breach

by such Seller of this Agreement.

9.8

Waiver. No failure or delay on the part of any Party in the exercise of any right hereunder will impair such right or

be construed to be a waiver of, or acquiescence in, any breach of any representation, warranty or agreement herein, nor will any single

or partial exercise of any such right preclude other or further exercise thereof or of any other right. At any time prior to the Closing,

any Party may, with respect to any other Party, (a) extend the time for the performance of any of the obligations or other acts, (b) waive

any inaccuracies in the representations and warranties contained herein or in any document delivered pursuant hereto and (c) waive compliance

with any of the agreements or conditions contained herein. Any such extension or waiver will be valid if set forth in an instrument in

writing signed by the Party or Parties to be bound.

9.9

Remedies Cumulative; Specific Performance. Except for the matters described in Section 8.3(c) as exclusive remedies,

all rights and remedies existing under this Agreement are cumulative to, and not exclusive of, any rights or remedies otherwise available.

Each Party agrees that, in the event of any breach or threatened breach by another Party of any covenant, obligation or other provision

set forth in this Agreement: (a) such first Party will be entitled, without any proof of actual damages (and in addition to any other

remedy that may be available to it) to: (i) a decree or order of specific performance or mandamus to enforce the observance and performance

of such covenant, obligation or other provision; and (ii) an injunction restraining such breach or threatened breach; and (b) such first

Party will not be required to provide any bond or other security in connection with any such decree, order or injunction or in connection

with any related action or Legal Proceeding.

9.10

Governing Law; Venue; Waiver of Jury Trial.

(a)

This Agreement (including, for the avoidance of doubt, appointment of the Sellers’ Representative pursuant to Section

1.6(b)) will be governed by, and construed in accordance with, the laws of the State of Nevada, regardless of the laws that might

otherwise govern under applicable principles of conflicts of laws thereof. Notwithstanding the foregoing, the Parties acknowledge and

agree that (i) the corporate existence, organization, internal affairs, and governance of Santersus, the validity, authorization, and

effectiveness under applicable Swiss Confederation law of any corporate action required to be taken by Santersus (or its shareholders,

board of directors, or any other corporate body) in connection with this Agreement and the transactions contemplated hereby, the validity

and effectiveness under applicable Swiss Confederation law of the transfer, issuance, cancellation, conversion, or registration (including

in any share register) of any shares or other equity interests of Santersus, and any other matter that is mandatorily governed by Swiss

Confederation law as a matter of applicable Swiss Confederation corporate law (collectively, the “Swiss Law Matters”),

will be governed by Swiss Confederation law. To the maximum extent permitted by applicable law, the Parties further agree that, in any

action or proceeding in which Swiss Law Matters are at issue, the court or tribunal may (and, upon request of any Party, shall) apply

Swiss Confederation law to such Swiss Law Matters and Nevada law to all other issues, without prejudice to the application of Nevada law

to the interpretation and enforcement of the contractual obligations set forth in this Agreement.

(b)

The Parties hereto agree that any Legal Proceeding seeking to enforce any provision of, or based on any matter arising out of or

in connection with, this Agreement or the Contemplated Transactions shall be brought in the courts of the State of Nevada, and any appellate

court from any thereof, or if no such state court has proper jurisdiction, the United States District Court for the District of Nevada.

Each Party hereto hereby irrevocably submits to the exclusive jurisdiction of such court in respect of any legal or equitable Legal Proceeding

arising out of or relating to this Agreement or the Contemplated Transactions, or relating to enforcement of any of the terms of this

Agreement, and hereby waives, and agrees not to assert, as a defense in any such Legal Proceeding, any claim that it is not subject personally

to the jurisdiction of such court, that the Legal Proceeding is brought in an inconvenient forum, that the venue of the Legal Proceeding

is improper or that this Agreement or the Contemplated Transactions may not be enforced in or by such courts. Each Party hereto agrees

that notice or the service of process in any Legal Proceeding arising out of or relating to this Agreement or the Contemplated Transactions

shall be properly served or delivered if delivered in the manner contemplated by Section 9.1 or in any other manner permitted by

applicable Legal Requirement.

(c)

EACH OF THE PARTIES HERETO HEREBY IRREVOCABLY WAIVES, TO THE EXTENT PERMITTED BY APPLICABLE LEGAL REQUIREMENTS, ANY AND ALL RIGHT

TO TRIAL BY JURY IN ANY ACTION, SUIT OR OTHER LEGAL PROCEEDING ARISING OUT OF OR RELATED TO THIS AGREEMENT OR THE CONTEMPLATED TRANSACTIONS.

9.11

Counterparts and Exchanges by Electronic Transmission or Facsimile. This Agreement may be executed in one or more counterparts,

and by the different parties hereto in separate counterparts and by facsimile or electronic (i.e., PDF) transmission, each of which when

executed will be deemed to be an original but all of which taken together will constitute one and the same agreement.

9.12

Attorney Fees. In any action at law or suit in equity to enforce this Agreement or the rights of any of the Parties

hereunder, the prevailing party in such action or suit will be entitled to receive a reasonable sum for its attorneys’ fees and

all other reasonable costs and expenses incurred in such action or suit upon the judgment in such action or suit becoming final and nonappealable.

9.13

Cooperation. Each Party agrees to cooperate fully with the other Parties hereto and to execute and deliver such further

documents, certificates, agreements and instruments and to take such other actions as may be reasonably requested by the other Parties

hereto to evidence or reflect the Contemplated Transactions and to carry out the intent and purposes of this Agreement and the Contemplated

Transactions.

9.14

Limited Survival of Representations and Warranties. The representations and warranties of Santersus, Sellers and Company

contained in this Agreement or any certificate or instrument delivered pursuant to this Agreement shall terminate at the Closing.

9.15

Construction.

(a)

For purposes of this Agreement, whenever the context requires: the singular number will include the plural, and vice versa; the

masculine gender will include the feminine and neuter genders; the feminine gender will include the masculine and neuter genders; and

the neuter gender will include masculine and feminine genders.

(b)

The Parties agree that any rule of construction to the effect that ambiguities are to be resolved against the drafting party will

not be applied in the construction or interpretation of this Agreement.

(c)

As used in this Agreement, the words “include” and “including,” and variations thereof, will not be deemed

to be terms of limitation, but rather will be deemed to be followed by the words “without limitation.”

(d)

Except as otherwise indicated, all references in this Agreement to “Sections,” “Exhibits” and “Schedules”

are intended to refer to Sections of this Agreement and Exhibits or Schedules to this Agreement.

(e)

The term “knowledge of Company,” and all variations thereof, will mean the actual knowledge that the

Company Persons, or any of them, would have after reasonable inquiry of direct reports. The term “knowledge of Santersus,”

and all variations thereof, will mean the actual knowledge that the Santersus Persons, or any of them, would have after reasonable inquiry

of direct reports.

(f)

Unless otherwise specified, all calculations performed pursuant to the terms of this Agreement shall be calculated to four decimal

places (0.0001).

(g)

For purposes of this Agreement, information “provided to,” “made available to”, “supplied to”

or “to be supplied to” hereunder shall be deemed to include any information made available by Company to Santersus or by Santersus

to Company, as applicable, in the virtual dataroom(s) of Company or Santersus, as applicable, no later than forty-eight hours prior to

the date of this Agreement.

9.16

Release and Covenant Not to Sue. Effective as of the Closing, to the fullest extent permitted by applicable Legal Requirements,

each Seller, on behalf of itself and its Affiliates that own any equity interest in or of such Seller (the “Releasing Persons”),

hereby releases and discharges all of the Acquiring Companies and the Santersus Companies (the “Released Persons”)

from and against any and all actions, suits, proceedings, arbitration, complaint, charge, investigation, obligations, agreements, debts

and Liabilities whatsoever, whether known or unknown, both at law and in equity, which such Releasing Person now has, has ever had or

may hereafter have against the Acquiring Companies or the Santersus Companies arising on or prior to the Closing Date (the “Released

Claims”). From and after the Closing, each Releasing Person hereby irrevocably covenants to refrain from, directly or indirectly,

asserting any action, suit, or proceeding, or commencing or causing to be commenced, any action, suit, or proceeding of any kind against

the Released Persons, based upon any Released Claim. Notwithstanding anything herein to the contrary, the releases and restrictions set

forth in this Section 9.16 shall not apply to (a) any claims a Releasing Person may have against any party pursuant to the terms

and conditions of this Agreement or any Ancillary Agreements, (b) any claim arising out of Fraud, (c) any claim arising from the Released

Person’s status as a current of former employee of Santersus, including claims relating to any employment agreement, retention bonus

agreement, transaction bonus agreement, severance or other similar agreement or arrangement (in each case including any rights and obligations

thereunder) for individuals, whether or not continuing to be employed by any Santersus Company following the Closing, and also including

any earned but unpaid wages, salary, bonus or other compensation for services performed through the Closing by any employee of any Santersus

Company, whether or not continuing to be employed by any Santersus Company following the Closing.

IN WITNESS WHEREOF,

the undersigned have caused this Share Exchange Agreement to be executed as of the date first written above.

SANTERSUS AG

By: /s/ James Ladtkow

Name: James Ladtkow

Title: Chief Executive Officer

IN WITNESS WHEREOF,

the undersigned have caused this Share Exchange Agreement to be executed as of the date first written above.

XENETIC BIOSCIENCES, INC.

By: /s/ James Parslow

Name: James Parslow

Title: Interim Chief Executive Officer and Chief Financial Officer

IN WITNESS WHEREOF,

the undersigned have caused this Share Exchange Agreement to be executed as of the date first written above.

SELLERS:

By: /s/ Sergey Avutshenko

Sergey Avutshenko

IN WITNESS WHEREOF,

the undersigned have caused this Share Exchange Agreement to be executed as of the date first written above.

SELLERS:

By: /s/ Andrew Aswani

Andrew Aswani

IN WITNESS WHEREOF,

the undersigned have caused this Share Exchange Agreement to be executed as of the date first written above.

SELLERS:

By: /s/ Franklin Corbin III

Franklin Corbin III

IN WITNESS WHEREOF,

the undersigned have caused this Share Exchange Agreement to be executed as of the date first written above.

SELLERS:

By: /s/ Blaine Dowdle

Blaine Dowdle

IN WITNESS WHEREOF,

the undersigned have caused this Share Exchange Agreement to be executed as of the date first written above.

SELLERS:

By: /s/ Dmitry Genkin

Dmitry Genkin

IN WITNESS WHEREOF,

the undersigned have caused this Share Exchange Agreement to be executed as of the date first written above.

SELLERS:

By: /s/ Jacques Hennessy

Jacques Hennessy

IN WITNESS WHEREOF,

the undersigned have caused this Share Exchange Agreement to be executed as of the date first written above.

SELLERS:

By: /s/ Nicholas Oscar Hodgson

Nicholas Oscar Hodgson

IN WITNESS WHEREOF,

the undersigned have caused this Share Exchange Agreement to be executed as of the date first written above.

SELLERS:

By: /s/ Shannon Hope

Shannon Hope

IN WITNESS WHEREOF,

the undersigned have caused this Share Exchange Agreement to be executed as of the date first written above.

SELLERS:

By: /s/ Jonathan Lane

Jonathan Lane

IN WITNESS WHEREOF,

the undersigned have caused this Share Exchange Agreement to be executed as of the date first written above.

SELLERS:

By: /s/ Steve Daniel Livshin

Steve Daniel Livshin

IN WITNESS WHEREOF,

the undersigned have caused this Share Exchange Agreement to be executed as of the date first written above.

SELLERS:

By: /s/ Svetlana Maguire

Svetlana Maguire

IN WITNESS WHEREOF,

the undersigned have caused this Share Exchange Agreement to be executed as of the date first written above.

SELLERS:

By: /s/ Moshe Mizrahy

Moshe Mizrahy

IN WITNESS WHEREOF,

the undersigned have caused this Share Exchange Agreement to be executed as of the date first written above.

SELLERS:

By: /s/ Vladimir Nesteruk

Vladimir Nesteruk

IN WITNESS WHEREOF,

the undersigned have caused this Share Exchange Agreement to be executed as of the date first written above.

SELLERS:

By: /s/ Hugh Osmond

Hugh Osmond

IN WITNESS WHEREOF,

the undersigned have caused this Share Exchange Agreement to be executed as of the date first written above.

SELLERS:

By: /s/ Jonathan Craig Quinnell

Jonathan Craig Quinnell

IN WITNESS WHEREOF,

the undersigned have caused this Share Exchange Agreement to be executed as of the date first written above.

SELLERS:

By: /s/ Kirill Surkov

Kirill Surkov

IN WITNESS WHEREOF,

the undersigned have caused this Share Exchange Agreement to be executed as of the date first written above.

SELLERS:

By: /s/ Simon Tallett

Simon Tallett

IN WITNESS WHEREOF,

the undersigned have caused this Share Exchange Agreement to be executed as of the date first written above.

SELLERS:

By: /s/ Alistair Wardell

Alistair Wardell

IN WITNESS WHEREOF,

the undersigned have caused this Share Exchange Agreement to be executed as of the date first written above.

SELLERS:

By: /s/ Aleksandr Zaporoztsev

Aleksandr Zaporoztsev

IN WITNESS WHEREOF,

the undersigned have caused this Share Exchange Agreement to be executed as of the date first written above.

SELLERS:

DEXAMENOS DEVELOPPEMENT SA SPF

By: /s/ Leonardo Vozzi

Name: Leonardo Vozzi

Title: Authorized Signatory

By: /s/ Manuel Hack

Name: Manuel Hack

Title: Authorized Signatory

IN WITNESS WHEREOF,

the undersigned have caused this Share Exchange Agreement to be executed as of the date first written above.

SELLERS:

MEDECI SERVICES LIMITED

By: /s/ Walter Reich

Name: Walter Reich

Title: Director

IN WITNESS WHEREOF,

the undersigned have caused this Share Exchange Agreement to be executed as of the date first written above.

SELLERS:

NORCLIFFE NOMINEES

LIMITED

By: /s/ Anna Long

Name: Anna Long

Title: Director

IN WITNESS WHEREOF,

the undersigned have caused this Share Exchange Agreement to be executed as of the date first written above.

SELLERS:

NUCLEOCON

SAKARTVELO LLC

By: /s/ Dmitry Genkin

Name: Dmitry Genkin

Title: Director

IN WITNESS WHEREOF,

the undersigned have caused this Share Exchange Agreement to be executed as of the date first written above.

SELLERS:

TERUMO AMERICAS

HOLDING, INC.

By: /s/ Katsuyuki Honda

Name: Katsuyuki Honda

Title: President and CEO

IN WITNESS WHEREOF,

the undersigned have caused this Share Exchange Agreement to be executed as of the date first written above.

SELLERS:

USP MEDICAL LTD

By: /s/ Peter George

Name: Professor Peter George

Title: Authorized Signatory

100

EXHIBIT A

CERTAIN DEFINITIONS

For purposes of this Agreement (including this

Exhibit A):

“Acquiring Companies”

means Company and its Subsidiaries.

“Acquisition Proposal”

means any offer, proposal, inquiry or indication of interest contemplating or otherwise relating to any Acquisition Transaction.

“Acquisition Transaction”

means any transaction or series of transactions involving:

(a)any

merger, consolidation, amalgamation, share exchange, business combination, issuance of securities, acquisition of securities, tender offer,

exchange offer or other similar transaction (i) in which Company (or its Subsidiaries) is a constituent corporation, (ii) in which a Person

or “group” (as defined in the Exchange Act and the rules promulgated thereunder) of Persons directly or indirectly acquires

beneficial or record ownership of securities representing more than twenty-five percent (25%) of the outstanding securities of any class

of voting securities of Company (or its Subsidiaries) or (iii) in which Company (or its Subsidiaries) issues securities representing more

than twenty-five percent (25%) of the outstanding securities of any class of voting securities of any such Entity (other than as contemplated

under this Agreement);

(b)any

sale, lease, exchange, transfer, license, acquisition or disposition of any business or businesses or assets that constitute or account

for twenty-five percent (25%) or more of the consolidated net revenues, net income or assets of Company (or its Subsidiaries); or

(c)any

liquidation or dissolution of any of Company (or its Subsidiaries);

provided, however,

that this Agreement and the transactions contemplated hereby shall not be deemed an Acquisition Transaction.

“Affiliates”

means, with respect to any Person, any other Person which directly or indirectly controls, is controlled by or is under common control

with such first Person. For this purpose, “control” (including, with its correlative meanings, “controlled by”

and “under common control with”) shall mean the possession, directly or indirectly, of the power to direct or cause the direction

of management or policies of a Person, whether through the ownership of securities or partnership or other ownership interests, by contract

or otherwise.

“Aggregate Valuation”

means the sum of (a) the Company Valuation, plus (b) the Santersus Valuation.

“Ancillary Agreements”

mean the Exchange Agent Agreement, the Santersus Lock-Up Agreements, the Company Lock-Up Agreements, and the Company Voting Agreements.

“Business Day”

means a day other than a Saturday, Sunday or other day on which commercial banks located in Boston, Massachusetts or Zürich, Switzerland

are authorized or required by applicable Legal Requirements to close.

101

“Code”

shall mean the Internal Revenue Code of 1986, as amended.

“Company Allocation

Percentage” means the quotient (rounded to two decimal places) determined by dividing (i) the Company Valuation by (ii)

the Aggregate Valuation.

“Company Closing

Price” means the volume weighted average closing trading price of a share of Company Common Stock on Nasdaq for the five

(5) consecutive trading days ending the trading day immediately prior to the Delivery Date.

“Company Common

Stock” means the Common Stock of Company, par value $0.001.

“Company Disclosure

Schedule” means the disclosure schedule that has been delivered by Company to Santersus as of the date hereof.

“Company IP Rights”

means all IP Rights in which an Acquiring Company has any right, title or interest or which are used or held for use by an Acquiring Company.

“Company Material

Adverse Effect” means any Effect that, considered together with all other Effects, has, or is reasonably expected to have,

a material adverse effect on: (a) the business, financial condition, operations or results of operations of the Acquiring Companies taken

as a whole; provided, however, that in no event shall any of the following, alone or in combination, be deemed to constitute,

nor shall any of the following be taken into account in determining whether there has occurred, a Company Material Adverse Effect: Effects

resulting from (i) conditions generally affecting the industries in which the Acquiring Companies participate or the United States or

global economy or capital markets as a whole, to the extent that such conditions do not have a disproportionate impact on the Acquiring

Companies, taken as a whole, relative to other companies in the industry in which the Acquiring Companies operate; (ii) changes in the

trading price or trading volume of Company Common Stock (it being understood, however, that any Effect causing or contributing to such

changes in the trading price or trading volume of Company Common Stock may constitute a Company Material Adverse Effect and may be taken

into account in determining whether a Company Material Adverse Effect has occurred); (iii) any failure by Company to meet any Company

estimates or expectations of Company’s development programs, any internal or analyst projections or forecasts or third party revenue

or earnings predictions for any period ending (or for which revenues or earnings are released) on or after the date hereof (it being understood,

however, that any Effect causing or contributing to such failures to meet projections or forecasts may constitute a Company Material Adverse

Effect and may be taken into account in determining whether a Company Material Adverse Effect has occurred); (iv) the execution, delivery,

announcement or performance of the obligations under this Agreement or the announcement, pendency or anticipated consummation of the Contemplated

Transactions; (v) any natural disaster or any acts of terrorism, sabotage, military action or war or any escalation or worsening thereof,

or any viruses, pandemics, epidemic or other outbreak of illness or public health event, or any spread or worsening thereof, or any other

Effect that may be considered a force majeure event; (vi) any changes (after the date hereof) in GAAP or applicable Legal Requirements

(or, in each case, the interpretation thereof) to the extent that such conditions do not have a disproportionate impact on the Acquiring

Companies, taken as a whole, relative to other companies in the industry in which the Acquiring Companies operate; (vii) general conditions

in financial markets, and any changes therein (including any changes arising out of acts of terrorism, war, weather conditions or other

force majeure event), to the extent that such conditions and changes do not have a disproportionate impact on the Acquiring Companies,

taken as a whole, relative to other companies in the industry in which the Acquiring Companies operate or to which other companies undertaking

transactions similar to the Contemplated Transactions may be subject; (viii) the taking of any action, or the failure to take any action,

by any Acquiring Company, that is required or reasonably necessary to comply with the terms of this Agreement or the taking of any action

permitted by Schedule 5.1; (ix) any changes in or affecting research and development, clinical trials or other drug development

activities (including the failure to obtain positive results from clinical trials, the occurrence of adverse events or serious adverse

events in any clinical trial, development activities or favorable responses from any applicable Governmental Body) conducted by or on

behalf of an Acquiring Company or licensees in respect of Company’s products or product candidates; (x) regulatory approval of,

or regulatory action or announcement with respect to, any product, or product candidates, of a third party that are similar to, or expected

to compete against, any of Company’s product candidates; or (xi) any stockholder or derivative litigation arising from or relating

to this Agreement or the Contemplated Transactions; or (b) the ability of Company to consummate the Acquisition or to perform any of its

covenants or obligations under this Agreement.

102

“Company Option”

means an option to purchase shares of Company Common Stock granted under the Company Option Plan.

“Company Option

Plan” means the Amended and Restated Equity Incentive Plan, effective as of December 7, 2021.

“Company Outstanding

Shares” means, subject to Section 1.4(c), the total number of shares of Company Common Stock outstanding immediately

prior to the Closing expressed on a fully-diluted basis and as-converted to Company Common Stock basis assuming, without limitation or

duplication, (a) the exercise of each Company Option outstanding and unexercised immediately prior to the Closing, excluding any portion

thereof which cannot become vested or exercisable or will otherwise not be outstanding immediately after the Closing, and (b) the issuance

of all shares of Company Common Stock issuable upon the vesting and settlement of each share of Company Restricted Stock outstanding immediately

prior to the Closing, whether or not then vested.

“Company Owned

IP Rights” shall mean all Company Registered IP Rights owned by any Acquiring Company and all other IP Rights owned by any

Acquiring Company that were developed by an Acquiring Company or were developed by a third party and subsequently assigned to any Acquiring

Company.

“Company Personnel”

means all the employees, directors and other officers of the Acquiring Companies, and any other individuals engaged to perform services

personally to the Acquiring Companies.

“Company Persons”

means James Parslow.

“Company Restricted

Stock” means restricted stock granted under the Company Option Plan that entitles the holder thereof to a share of Company

Common Stock upon vesting or settlement, either as a result of time or performance metrics.

“Company Stockholder

Approval Matters” means the approval of (i) the issuance of the Acquisition Consideration required by Nasdaq, (ii) an amendment

to the Company’s Articles of Incorporation to increase the number of authorized shares and change the name of Company to “Santersus

Bio, Inc.,” and (iii) any amendments to, or adoption of, any option or warrant plans to give effect to the Contemplated Transactions.

“Company Stockholder

Approval Threshold” means (i) with respect to the approval of the amendment to the Company’s Organizational Documents

to increase the number of authorized shares of Company Common Stock and change the name of the Company, the affirmative vote of a majority

of the voting power of the capital stock of Company entitled to vote thereon, and (ii) with respect to each other Company Stockholder

Approval Matter, the affirmative vote of a majority of the votes cast affirmatively or negatively on such Company Stockholder Approval

Matter by the holders of the capital stock of Company entitled to vote thereon present or represented by proxy.

“Company Stockholders”

means the holders of the issued and outstanding shares of Company Common Stock.

“Company Valuation”

means $21,000,000 plus Net Cash of the Company.

“Company Warrant”

means any outstanding warrants to purchase shares of Company Common Stock.

“Consent”

means any approval, consent, ratification, permission, waiver or authorization.

“Contemplated

Transactions” means the Acquisition and the other transactions and actions contemplated by this Agreement.

103

“Contract”

means any written or oral agreement, contract, subcontract, lease, understanding, arrangement, instrument, note, option, warranty, purchase

order, license, sublicense, insurance policy or legally binding commitment or undertaking of any nature.

“Copyrights”

means all copyrights and copyrightable works (whether or not registered, and including without limitation databases and other compilations

of information) that may exist or be created under the laws of any jurisdiction, including all rights in works of authorship, use, publication,

reproduction, distribution, public performance, public display, in the creation of derivative works, sound recordings, transformation,

moral rights and rights of ownership of copyrightable works and all registrations and rights to register and obtain renewals and extensions

of registrations.

“Designation Period”

means a period of time ending as of the close of business, Eastern Time, on the thirtieth (30th) day following the date of

this Agreement.

“Domestic Partner”

mean, with respect to any individual, a person who is in a domestic partnership, civil union or other legally recognized relationship

with such individual under applicable Legal Requirements that confer rights and obligations substantially similar to those of marriage.

“Effect”

means any event, development, circumstance, change, effect or occurrence.

“Encumbrance”

means any lien, pledge, hypothecation, charge, mortgage, easement, encroachment, imperfection of title, title exception, title defect,

right of possession, lease, tenancy license, security interest, encumbrance, claim, infringement, interference, preemptive right, community

property interest or restriction of any nature (including any restriction on the voting of any security, any restriction on the transfer

of any security or other asset, any restriction on the receipt of any income derived from any asset, any restriction on the use of any

asset and any restriction on the possession, exercise or transfer of any other attribute of ownership of any asset).

“End Date”

means March 31, 2027.

“Entity”

means any corporation (including any non-profit corporation), general partnership, limited partnership, limited liability partnership,

joint venture, estate, trust, company (including any company limited by shares, limited liability company or joint stock company), firm,

society or other enterprise, association, organization or entity.

“Environmental

Law” means any federal, state, local or foreign Legal Requirement relating to pollution or protection of human health or

the environment (including ambient air, surface water, ground water, land surface or subsurface strata), including any law or regulation

relating to emissions, discharges, releases or threatened releases of Hazardous Materials, or otherwise relating to the manufacture, processing,

distribution, use, treatment, storage, disposal, transport or handling of Hazardous Materials.

“Exchange Ratio”

means, subject to Section 1.4(c), the following ratio (rounded to four decimal places): the quotient obtained by dividing (a) the

Santersus Transaction Shares by (b) the Santersus Outstanding Shares. For the avoidance of doubt and for illustrative purposes only, a

sample “Exchange Ratio” calculation is attached hereto as Exhibit G.

“FDA”

means the United States Food and Drug Administration.

104

“Fraud”

means, with respect to any party hereto, any actual and intentional misrepresentation of a material fact by such party with respect to

(a) any of such party’s representations and warranties set forth in this Agreement or (b) in any certificate delivered by such party

pursuant to this Agreement (as qualified by the Schedules accompanying this Agreement), where (i) the party making such representation

or warranty had actual knowledge (and not imputed or constructive knowledge) that such representation or warranty was false or misleading

when made, (ii) such misrepresentation was made with the specific intent to induce another party hereto to take or refrain from taking

action in reliance thereon, and (iii) such other party actually and reasonably relied on such representation or warranty to its detriment.

For the avoidance of doubt, “Fraud” does not include any claim for equitable fraud, promissory fraud, unfair dealings fraud,

constructive fraud or any torts (including a claim for fraud) based on negligence or recklessness.

“Governmental

Body” means any: (a) nation, state, commonwealth, province, territory, county, municipality, district or other jurisdiction

of any nature; (b) federal, state, local, municipal, foreign or other government; or (c) governmental or quasi-governmental authority

of any nature (including any governmental executive, division, regulatory agency, department, agency, commission, instrumentality, official,

ministry, fund, foundation, center, organization, unit, body or Entity and any court or other tribunal).

“Hazardous Materials”

means any pollutant, chemical, substance and any toxic, infectious, carcinogenic, reactive, corrosive, ignitable or flammable chemical,

or chemical compound, or hazardous substance, material or waste, whether solid, liquid or gas, that is subject to regulation, control

or remediation under any Environmental Law, including crude oil or any fraction thereof, and petroleum products or by-products.

“Insolvency Proceedings”

means insolvency related proceedings, whether in or out of court, including proceedings or steps leading to any form of bankruptcy, liquidation,

administration, receivership, arrangement or scheme with creditors, moratorium, stay or limitation of creditors’ rights, interim

or provisional supervision by a court or court appointee, winding up or striking off or any event similar to any such events in any jurisdiction

in which a Seller is resident or incorporated.

“Intervening Event”

means a material event, circumstance, change or development that (i) was not known to, or reasonably foreseeable by, the board of directors

of the Company after making reasonable inquiry of the executive officers of the Company (or, if such inquiry is not made, that would not

have been known or reasonably foreseeable to the board of directors of the Company) prior to the execution of this Agreement, and that

first becomes known or reasonably foreseeable to the board of directors of Company after the date of this Agreement, which event, circumstance,

change or development, or any material consequence thereof, becomes known to, or reasonably foreseeable by, the board of directors of

the Company prior to the receipt of the Company Stockholder Approval and (ii) does not relate to an Acquisition Proposal; provided,

that “Intervening Event” shall exclude any event, circumstance, change or development related to (A) any Acquisition Proposal

or other inquiry, offer or proposal that would reasonably be expected to lead to an Acquisition Proposal, (B) consisting of or resulting

from a breach of this Agreement by the Company or any of its Subsidiaries, (C) changes in the price of the Company Common Stock, in and

of itself (however, the underlying reasons for such changes may constitute an Intervening Event unless excluded by any other exclusion

in this definition), (D) the fact that, in and of itself, the Company exceeds any internal or published budgets, projections, estimates

or expectations of the Company’s revenue, earnings or other financial performance or results of operations for any period, in and

of itself (provided, that the underlying reasons for the Company exceeding such budgets, projections, estimates or expectations

may constitute an Intervening Event unless excluded by any other exclusion in this definition) or (E) an event that relates solely to

Santersus.

“IP Rights”

means any and all of the following in any country or region: (a) Copyrights, Patent Rights, Trademark Rights (including domain name registrations),

Trade Secrets, and other intellectual property rights; and (b) the right (whether at law, in equity, by Contract or otherwise) to enjoy

or otherwise exploit any of the foregoing, including the rights to sue for and remedies against past, present and future infringements

of any or all of the foregoing, and rights of priority and protection of interests therein under the Legal Requirements of any jurisdiction

worldwide.

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“Legal Proceeding”

means any action, suit, litigation, arbitration, mediation, proceeding (including any civil, criminal, administrative, insolvency, bankruptcy,

liquidation, administration, receivership, involuntary arrangement, compromise or schedule with creditors, moratorium, stay or limitation

of creditors rights, interim or provisions supervision by a court or court appointee, winding up or striking off, or similar event, investigative

or appellate proceeding), hearing, inquiry, audit, examination, conciliation, expert determination or investigation or other process commenced,

brought, conducted or heard by or before, or otherwise involving, any court or other Governmental Body or any arbitrator or arbitration

panel.

“Legal Requirements”

means any federal, state, local, municipal, foreign or other law, statute, constitution, principle of common law, resolution, ordinance,

code, edict, decree, rule, regulation, ruling or requirement issued, enacted, adopted, promulgated, implemented or otherwise put into

effect by or under the authority of any Governmental Body (or under authority of Nasdaq or any other applicable securities exchange).

“Nasdaq”

means The Nasdaq Stock Market.

“Net Cash”

means the sum of (without duplication) (a) as of the Cash Determination Time, the sum of Company’s and its Subsidiaries’ cash

and cash equivalents (excluding any restricted cash or cash subject to any encumbrance, escrow, pledge or other restriction on use) and

marketable securities, accounts receivable (other than (x) intercompany receivables and (y) accounts receivable that have been

outstanding for more than ninety (90) days past their applicable invoice date), interest and other receivables (other than intercompany

receivables) minus (b) as of the Cash Determination Time, the sum of (i) all accounts payable and accrued expenses (including Transaction

Costs) of Company and its Subsidiaries, determined in a manner consistent with the manner in which such items were historically determined

and in accordance with the Company Financials and the Company Balance Sheet, and any and all other bona fide current and long-term

Liabilities of Company and its Subsidiaries payable in cash that would be required to be set forth in a balance sheet of Company and its

Subsidiaries prepared in accordance with GAAP, in each case to the extent not paid or canceled at or prior to the Closing Date,

(ii) all outstanding Indebtedness for borrowed money of Company and its Subsidiaries, including accrued and unpaid interest thereon and

any prepayment penalties, breakage costs, premiums, fees or other costs or expenses payable in connection with the repayment or retirement

thereof at or prior to the Closing Date, (iii) all unpaid income, franchise, sales, use, employment and other Taxes of Company and its

Subsidiaries that have accrued or are attributable to any Pre-Closing Period, whether or not then due and payable, (iv) the cash cost

of any transaction bonuses, unpaid change of control payments or severance, termination or similar payments or obligations, including

any COBRA-related obligations or employer portion of payroll or other Taxes owed (including any Taxes under Section 4999 that the

Company or any of its Affiliates has agreed or is required to reimburse, indemnify, pay, or gross up for any Person), as well as the amount

equal to the sum of any loss of deduction under Section 280G, in connection with the foregoing, that are or become due to any current

or former employee, director or independent contractor of Company or any of its Subsidiaries in connection with, or at the time of, Closing,

(v) all accrued but unpaid compensation, bonuses, commissions, and accrued but unused vacation or paid time off obligations owed to any

current or former employee, director or independent contractor of Company or any of its Subsidiaries plus (c) any prepaid expenses.

A sample calculation of Net Cash is set forth on Exhibit F for illustrative purposes only. Net Cash shall be denominated

in U.S. dollars and each component initially denominated in a different currency shall be converted based on the published Wall Street

Journal rate as of the Cash Determination Time.

“Norcliffe Agreement”

means that certain Share Transfer Agreement, to be entered into contemporaneously with this Agreement, by and between Norcliffe Capital

Limited, the selected shareholders set forth therein, and Santersus.

“Order”

means any order, writ, injunction, judgment or decree.

“Organizational

Documents” means, collectively and as applicable, the certificate of incorporation, articles of incorporation, memorandum

of association, articles of association, bylaws and other charter documents of a company.

“Organox Agreement”

means that certain Research Collaboration Agreement, dated as of June 26, 2023, by and between Organox Limited and Santersus.

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“Patent Rights”

means all issued patents, pending patent applications and abandoned patents and patent applications provided that they can be revived

(which for purposes of this Agreement will include utility models, design patents, industrial designs, certificates of invention and applications

for certificates of invention and priority rights) in any country or region, including all provisional applications, substitutions, continuations,

continuations-in-part, divisions, renewals, reissues, re-examinations and extensions thereof.

“Permitted Encumbrances”

means any (a) Encumbrances in respect of Taxes not yet due and payable or Encumbrances in respect of Taxes the validity of which is being

contested in good faith by appropriate proceedings and, in each case, for which adequate reserves with respect thereto are maintained

on the books of the applicable Person in accordance with GAAP; (b) mechanics’, carriers’, workmen’s, repairmen’s,

statutorily imposed or other similar Encumbrances arising or incurred in the ordinary course of business, for amounts not yet due and

payable, or which are being contested in good faith by appropriate proceedings and for which adequate reserves with respect thereto are

maintained on the books of the applicable Person in accordance with GAAP; (c) Encumbrances arising under original purchase price

conditional sales Company Contracts or Santersus Contracts and equipment leases with third parties; (d) limitations on the rights

of any Person under any Contract or real property lease that are expressly set forth in such Contract or real property lease or Encumbrances

undertaken by the respective landlord thereunder, in each case, which do not materially interfere with the present use, access to or value

of the property it affects; (e) survey exceptions that would be disclosed by a current, accurate survey or physical inspection, imperfections

of title, Encumbrances or other title matters affecting any tangible asset owned by any Person that would not, individually or in the

aggregate, materially detract from the value of or materially impair the continued use and operation of the affected leased real property

of such Person to which they relate in the conduct of the business of such Person; (f) with respect to any leased real property of

a Person, zoning, building codes and other land use Legal Requirements regulating the use or occupancy of such leased real property or

the activities conducted thereon that are imposed by any Governmental Body having jurisdiction over such leased real property, and any

covenants, conditions, restrictions, easements and other similar matters of record affecting the leased real property of such Person,

none of which, individually or in the aggregate, materially detract from the value of or materially impair the continued use and occupation

of the affected leased real property to which they relate in the conduct of the business of such Person, and the interests and rights

of lessors with respect to the leased real property of such Person; (g) non-exclusive licenses of IP Rights granted to customers,

contractors and service providers in the ordinary course of business consistent with past practice and not material to the business or

the IP Rights; (h) Encumbrances which are specifically reflected on the Company Financials or Santersus Financials; (i) any other

Encumbrances that will be terminated at or prior to Closing in accordance with this Agreement; (j) restrictions on transfer of securities

imposed by applicable state and federal securities Legal Requirements; and (k) Liens imposed by Legal Requirements.

“Person”

means any person, Entity, Governmental Body, or group (as used in Section 13(d)(3) of the Exchange Act).

“Personal Data”

means a natural person’s name, street address, telephone number, e-mail address, photograph, social security number, driver’s

license number, passport number, biometric identifiers, financial account information, health information, or any other piece of information

that allows the identification of a natural person, or that constitutes “personal information,” “personal data,”

“personally identifiable information,” or an analogous term as defined in applicable data protection Legal Requirements.

“Post-Closing

Company Shares” mean the quotient (rounded to two decimal places) determined by dividing (i) the Company Outstanding Shares

by (ii) the Company Allocation Percentage.

“Related Party

Directors” means Dmitry Genkin, M.D. and Moshe Mizrahy.

“Resigning Company

Board Members” means each member of the board of directors of the Company that is not designated a Company Director pursuant

to Section 6.9.

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“Resigning Company

Officers” means each officer of the Company prior to the Closing that is not designated as an officer of the Company immediately

following the Closing pursuant to Section 6.9.

A Party’s “Representatives”

include each Person that is or becomes (a) a Subsidiary or other Affiliate of such Party or (b) an officer, director, employee, partner,

attorney, advisor, accountant, agent or representative of such Party or of any such Party’s Subsidiaries or other Affiliates.

“Santersus Acquisition

Proposal” means, subject to the proviso below, any offer, proposal, inquiry or indication of interest contemplating or otherwise

relating to any transaction or series of transactions involving:

(a)any

merger, consolidation, amalgamation, share exchange, business combination, acquisition of securities, tender offer, exchange offer or

other similar transaction (i) in which Santersus (or any of its Subsidiaries) is a constituent corporation, (ii) in which a Person or

“group” (as defined in the Exchange Act and the rules promulgated thereunder) of Persons directly or indirectly acquires beneficial

or record ownership of securities representing more than twenty-five percent (25%) of the outstanding securities of any class of voting

securities of Santersus (or any of its Subsidiaries) or (iii) in which Santersus (or any of its Subsidiaries) issues securities representing

more than twenty-five percent (25%) of the outstanding securities of any class of voting securities of any such Entity (other than as

contemplated under this Agreement);

(b)any

sale, lease, exchange, transfer, license, acquisition or disposition of any business or businesses or assets that constitute or account

for twenty-five percent (25%) or more of the consolidated net revenues, net income or assets of Santersus (or its Subsidiaries); or

liquidation or dissolution of any of Santersus (or its Subsidiaries);

provided, however,

that this Agreement and the transactions contemplated hereby shall not be deemed a Santersus Acquisition Proposal.

“Santersus Allocation

Percentage” means the quotient (rounded to two decimal places) determined by dividing (i) the Santersus Valuation by (ii)

the Aggregate Valuation.

“Santersus Companies”

means Santersus and its Subsidiaries.

“Santersus Data

Room” means the electronic documentation site hosted by Egnyte on behalf of Santersus.

“Santersus Disclosure

Schedule” means the disclosure schedule that has been delivered by Santersus to Company on the date hereof.

“Santersus IP

Rights” means all IP Rights in which a Santersus Company has any right, title or interest or which are used or held for

use by a Santersus Company.

108

“Santersus Material

Adverse Effect” means any Effect that, considered together with all other Effects, has, or is reasonably expected to have,

a material adverse effect on: (a) the business, financial condition, operations or results of operations of the Santersus Companies taken

as a whole; provided, however, that, in no event will any of the following, alone or in combination, be deemed to constitute,

nor will any of the following be taken into account in determining whether there has occurred, a Santersus Material Adverse Effect: Effects

resulting from (i) conditions generally affecting the industries in which Santersus participates or the United States or global economy

or capital markets as a whole, to the extent that such conditions do not have a disproportionate impact on the Santersus Companies, taken

as a whole, relative to other companies in the industry in which the Santersus Companies operate; (ii) any failure by the Santersus Companies

to meet any estimates or expectations of its development programs, internal projections or forecasts or third party revenue or earnings

predictions for any period ending (or for which revenues or earnings are released) on or after the date hereof (it being understood, however,

that any Effect causing or contributing to such failures to meet projections or predictions may constitute a Santersus Material Adverse

Effect and may be taken into account in determining whether a Santersus Material Adverse Effect has occurred); (iii) the execution, delivery,

announcement or performance of the obligations under this Agreement or the announcement, pendency or anticipated consummation of the Contemplated

Transactions; (iv) any natural disaster or any acts of terrorism, sabotage, military action or war or any escalation or worsening thereof,

or any viruses, pandemics, epidemic or other outbreak of illness or public health event, or any spread or worsening thereof, or any other

Effect that may be considered a force majeure event; (v) any changes (after the date hereof) in GAAP or applicable Legal Requirements

(or, in each case, the interpretation thereof) to the extent that such conditions do not have a disproportionate impact on the Santersus

Companies, taken as a whole, relative to other companies in the industry in which the Santersus Companies operate; (vi) the taking of

any action, or the failure to take any action, by any Santersus Company, that is required or reasonably necessary to comply with the terms

of this Agreement or the taking of any action permitted by Schedule 5.1; (vii) any changes in or affecting research and development,

clinical trials or other device development activities (including the failure to obtain positive results from clinical trials, the occurrence

of unanticipated adverse device effects in any clinical trial, development activities or favorable responses from any applicable Governmental

Body) conducted by or on behalf of a Santersus Company or licensees in respect of Santersus’ product candidates (it being understood,

however, that any effect of any such adverse device effect adverse event in any clinical trial (taking into account the intended patient

population) on any Santersus Company may be taken into account in determining whether a Santersus Material Adverse Effect has occurred);

or (b) the ability of Santersus or Sellers to consummate the Acquisition or to perform any of their respective covenants or obligations

under this Agreement.

“Santersus Option”

means any option to acquire shares in the capital of Santersus issued pursuant to the Santersus Option Plan.

“Santersus Option

Plan” means the Santersus Stock Option Plan 2025, as amended.

“Santersus Outstanding

Shares” means, subject to Section 1.4(c), the total number of Santersus Ordinary Shares outstanding immediately prior

to the Closing expressed on a fully-diluted basis and as converted to Santersus Ordinary Shares basis assuming, without limitation or

duplication, (i) the Santersus Share Conversion, (ii) the exercise of all Santersus Options outstanding as of immediately prior to the

Closing and (iii) the issuance of Santersus Ordinary Shares in respect of all other options, warrants or rights to receive Santersus Ordinary

Shares that will be outstanding immediately prior to the Closing.

“Santersus Personnel”

means all the employees, directors and other officers of the Santersus Companies, and any other individuals engaged to perform services

personally to the Santersus Companies.

“Santersus Persons”

means Andrew Aswani, James Ladtkow and Aleksandr Zaporoztsev.

“Santersus Share

Capital” means the Santersus Ordinary Shares and the Santersus Preferred Shares.

“Santersus Shareholders

Agreement” means the Shareholders’ Agreement of Santersus Ltd., dated September 29, 2025, by and among (i) the existing

shareholders listed on Annex A thereto, (ii) the Series A investors of Santersus and (iii) Santersus.

109

“Santersus Shares”

means the issued and outstanding Santersus Ordinary Shares, the Santersus Conversion Shares, and any Santersus Ordinary Shares issued

upon the exercise at or prior to Closing of Santersus Options.

“Santersus Transaction

Shares” means the product (rounded to two decimal places) determined by multiplying (i) the Post-Closing Company Shares

by (ii) the Santersus Allocation Percentage.

“Santersus Valuation”

means $120,000,000.

“SEC”

means the Securities and Exchange Commission in the United States.

“SEC Documents”

means each report, registration statement, proxy statement and other statements, reports, schedules, forms and other documents filed by

Company with the SEC since January 1, 2023, including all amendments thereto.

“Securities Act”

means the Securities Act of 1933, as amended.

An Entity will be deemed to

be a “Subsidiary” of another Person if such Person directly or indirectly owns, beneficially or of record, (a)

an amount of voting securities of or other interests in such Entity that is sufficient to enable such Person to elect at least a majority

of the members of such Entity’s board of directors or other governing body or (b) at least 50% of the issued or outstanding equity

or financial interests of such Entity.

“Superior Offer”

means a bona fide written Acquisition Proposal (provided that, for purposes of this definition, the references to 25% in the definition

of “Acquisition Transaction” shall be deemed to be references to 50%) made by a third party that was not obtained or made

as a result of a breach of Section 6.10(a)(i) and which the board of directors of Company determines in good faith (after consultation

with its outside legal counsel and financial advisor), and after taking into account all financial, legal, regulatory, and other aspects

of such Acquisition Proposal (including the financing terms and the ability of such third party to finance such Acquisition Proposal):

(a) to be reasonably likely to be consummated if accepted; and (b) to be more favorable to Company Stockholders from a financial point

of view than the Acquisition and is not subject to any financing condition (and if financing is required, such financing is then fully

committed pursuant to customary debt or equity commitment letters that contain only customary conditions), taking into account any changes

to the terms of this Agreement offered by Santersus or Sellers in response to such Acquisition Proposal.

“Tax”

and “Taxes” means any federal, state, local, or non-U.S. taxes imposed by a Governmental Body, including taxes

on or with respect to income, gross receipts, license, payroll, employment, excise, severance, stamp, occupation, premium, windfall profits,

customs duties, capital stock, franchise, profits, withholding, social security (or similar), unemployment, disability, real property,

personal property, sales, use, transfer, registration, value added, alternative or add-on minimum, estimated, or other tax of any kind

whatsoever, including any interest, penalty, or addition thereto, whether disputed or not.

“Tax Return”

means any report, return (including information return), claim for refund, election, estimated tax filing, declaration or similar return

filed, supplied or required to be filed with any Governmental Body with respect to Taxes, including any election, notification, appendix

schedule or attachment thereto, and including any amendments thereof.

“Trade Secrets”

means trade secrets, know-how, proprietary information, inventions, discoveries, improvements, technology, technical data and research

and development, whether patentable or not.

110

“Trademark Rights”

means all trademark rights that may exist or be created under the laws of any jurisdiction in the world including all material common

law trademarks, registered trademarks, applications for registration of trademarks, material common law service marks, registered service

marks, applications for registration of service marks, trade names, registered trade names and applications for registration of trade

names, and Internet domain name registrations; and including all filings with the applicable Governmental Body indicating an intent to

use any of the foregoing if not registered or subject to a pending application, and to the extent applicable all renewals and extensions

thereof.

“Transaction Costs”

means all fees and expenses incurred by the Acquiring Companies (or expected to be incurred based on receipt of a good faith written estimate)

in connection with the negotiation, preparation and execution of this Agreement and the consummation of the Contemplated Transactions,

to the extent not otherwise taken into account in the calculation of “Net Cash,” including (a) any fees and expenses of legal

counsel and accountants and the maximum amount of fees and expenses payable to financial advisors, investment bankers, brokers, consultants,

and other advisors of the Acquiring Companies in connection with the negotiation, preparation and execution of this Agreement and the

consummation of the Contemplated Transactions (including in connection with any stockholder litigation relating to this Agreement or any

of the Contemplated Transactions), including finders’ fees; (b) fees paid to the SEC in connection with filing the Registration

Statement, the Proxy Statement, and any amendments and supplements thereto, with the SEC; (c) any fees and expenses in connection with

the printing, mailing and distribution of the Proxy Statement and any amendments and supplements thereto; (d) 50% of the fees and expenses

payable to Nasdaq in connection with the Nasdaq Listing Application; (e) any bonus, severance, change-in-control or retention payments

or similar payment or other obligations (including payments or other obligations with “single-trigger” provisions triggered

at and as of the Closing) that become due or payable to any director, officer, employee or consultant of Acquiring Companies or any of

its Subsidiaries in connection with the consummation of the Contemplated Transactions, including any COBRA-related obligations, employer

portion of payroll or other Taxes (including under Section 4999 that the Company or any of its Affiliates has agreed or is required to

reimburse, indemnify, pay, or gross up for any Person), as well as the amount equal to the sum of any loss of deduction under Section

280G in connection with the foregoing; (f) fifty percent (50%) of the D&O Tail described in Section 6.5(b); and (g) any

notice payments, change-of-control payments, fines or other payments which become payable by any Acquiring Company in connection with

terminating at Closing any existing Contract to which an Acquiring Company is a party at or prior to the Closing.

“Willful Breach”

means an act or omission with the actual knowledge that such act or omission represents, or would cause, a breach of this Agreement. With

respect to the Company, such act or omission, or such “actual knowledge” shall include the officers and the non-Related Party

Directors of the Company.

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Additionally, the following

terms have the meanings assigned to such terms in the Sections of this Agreement set forth below opposite such term:

Defined Term

Section

Acceptable Company Confidentiality Agreement

Section 6.10(a)(i)

Accounting Firm

Section 1.5(e)

Acquiring Companies

Exhibit A

Acquisition

Section 1.1

Acquisition Consideration

Section 1.4(a)

Acquisition Proposal

Exhibit A

Acquisition Transaction

Exhibit A

Action

Section 5.1(t)

Affiliates

Exhibit A

Aggregate Valuation

Exhibit A

Agreement

Preface

Ancillary Agreements

Exhibit A

Anti-Corruption Laws

Section 2.9(f)

Anti-Money Laundering Laws

Section 3.10(e)

Business Day

Exhibit A

Cash Determination Time

Section 1.5(a)

Clearance Date

Section 6.1(a)

Closing

Section 1.2

Closing Date

Section 1.2

Code

Exhibit A

Company

Preface

Company Allocation Percentage

Exhibit A

Company Balance Sheet

Section 3.5(f)

Company Board Recommendation

Section 6.2(b)

Company Change in Recommendation

Section 6.2(c)

Company Closing Price

Exhibit A

Company Code

Section 3.8(k)

Company Common Stock

Exhibit A

Company Contract

Section 3.17(a)

Company Disclosure Schedule

Exhibit A

Company Employee Plans

Section 3.13(a)

Company ERISA Affiliate

Section 3.13(a)

Company Financials

Section 3.5(f)

Company IP Rights

Exhibit A

Company IT Systems and Data

Section 3.9(c)

Company Lock-Up Agreements

Recital

112

Company Lock-Up Party

Recital

Company Material Adverse Effect

Exhibit A

Company Option

Exhibit A

Company Option Plan

Exhibit A

Company Outstanding Shares

Exhibit A

Company Outstanding Shares Certificate

Section 6.16(b)

Company Owned IP Rights

Exhibit A

Company Permits

Section 3.10(c)

Company Personnel

Exhibit A

Company Persons

Exhibit A

Company Plan

Section 3.13(a)

Company Preferred Stock

Section 3.2(a)

Company Reports

Section 3.5(a)

Company Restricted Stock

Exhibit A

Company Series A Preferred Stock

Section 3.2(a)

Company Series B Preferred Stock

Section 3.2(a)

Company Stockholder Approval

Section 3.3(a)

Company Stockholder Approval Matters

Exhibit A

Company Stockholder Approval Threshold

Exhibit A

Company Stockholders

Exhibit A

Company Stockholders’ Meeting

Section 6.2(a)

Company Termination Fee

Section 8.3(b)

Company Valuation

Exhibit A

Company Voting Agreements

Recital

Company Warrant

Exhibit A

Confidential Information Agreements

Section 2.7(i)

Confidentiality Agreement

Section 6.3

Consent

Exhibit A

Contemplated Transactions

Exhibit A

Contract

Exhibit A

Copyrights

Exhibit A

D&O Indemnified Parties

Section 6.5(a)

D&O Tail

Section 6.5(b)

Defaulting Party

Section 8.3(e)

Delivery Date

Section 1.5(a)

Designated Parties

Section 2.9(e)

Dispute Notice

Section 1.5(b)

Effect

Exhibit A

Encumbrance

Exhibit A

End Date

Exhibit A

Entity

Exhibit A

Environmental Law

Exhibit A

113

Environmental Laws

Section 2.15

ERISA

Section 2.13(a)

Exchange Agent

Section 1.7(a)

Exchange Agent Agreement

Section 1.7(a)

Exchange Ratio

Exhibit A

FDA

Exhibit A

FDA Application Integrity Policy

Section 2.9(h)

Federal Securities Laws

Section 6.23

GAAP

Section 2.4(a)

Governmental Body

Exhibit A

Hazardous Materials

Exhibit A

Insolvency Proceedings

Exhibit A

Insurance Policies

Section 2.18(a)

Intervening Event

Exhibit A

IP Rights

Exhibit A

Joinder Agreement

Section 6.11(b)

knowledge of Company

Section 9.15(e)

knowledge of Santersus

Section 9.15(e)

Legal Proceeding

Exhibit A

Legal Requirements

Exhibit A

Liability

Section 2.4(d)

Nasdaq

Exhibit A

Nasdaq Listing Application

Section 6.13

Net Cash

Exhibit A

Net Cash Calculation

Section 1.5(a)

Net Cash Schedule

Section 1.5(a)

Notice Period

Section 6.2(c)

Open Source Software

Section 2.7(k)

Order

Exhibit A

Organizational Documents

Exhibit A

Parties

Preface

Party

Preface

Patent Rights

Exhibit A

PEO

Section 3.13(a)

PEO Plan

Section 3.13(a)

Permitted Encumbrances

Exhibit A

Permitted Transferee

Section 6.11(b)

Person

Exhibit A

Personal Data

Exhibit A

Post-Closing Company Shares

Exhibit A

Pre-Closing Period

Section 5.1

Protected Program

Section 6.24

Proxy Statement

Section 6.1(a)

Registration Statement

Section 6.1(a)

114

Released Claims

Section 9.16

Released Persons

Section 9.16

Releasing Persons

Section 9.16

Representatives

Exhibit A

Response Date

Section 1.5(b)

Restricted Countries

Section 2.9(e)

Sanctions

Section 2.9(e)

Santersus

Preface

Santersus Acquisition Proposal

Exhibit A

Santersus Allocation Certificate

Section 6.16(a)

Santersus Allocation Percentage

Exhibit A

Santersus Audited Financials

Section 2.4(a)

Santersus Code

Section 2.7(k)

Santersus Companies

Exhibit A

Santersus Contract

Section 2.17(b)

Santersus Conversion Shares

Recital

Santersus Data Room

Exhibit A

Santersus Disclosure Schedule

Exhibit A

Santersus Employee Plans

Section 2.13(a)

Santersus Financials

Section 2.4(b)

Santersus IP Rights

Exhibit A

Santersus Issued Share Capital

Section 2.2(a)

Santersus IT Systems and Data

Section 2.8(c)

Santersus Lock-Up Agreements

Recital

Santersus Lock-Up Party

Recital

Santersus Material Adverse Effect

Exhibit A

Santersus Option

Exhibit A

Santersus Option Plan

Exhibit A

Santersus Ordinary Shares

Section 2.2(a)

Santersus Outstanding Shares

Exhibit A

Santersus Permits

Section 2.9(d)

Santersus Personnel

Exhibit A

Santersus Persons

Exhibit A

Santersus Preferred Shares

Section 2.2(a)

Santersus Share Capital

Exhibit A

Santersus Share Conversion

Recital

Santersus Shareholders Agreement

Exhibit A

Santersus Shares

Exhibit A

Santersus Transaction Shares

Exhibit A

Santersus Unaudited Financials

Section 2.4(b)

Santersus Valuation

Exhibit A

115

Sarbanes-Oxley Act

Section 3.5(b)

SEC

Exhibit A

SEC Documents

Exhibit A

Securities Act

Exhibit A

Seller Representative

Preface

Sellers

Preface

Share Assignment Declaration

Section 1.7(b)

Standard Inbound Agreements

Section 2.7(g)

Standard Outbound Agreements

Section 2.7(f)

Subsidiary

Exhibit A

Superior Offer

Exhibit A

Swiss Law Matters

Section 9.10(a)

Tax

Exhibit A

Tax Return

Exhibit A

Trade Secrets

Exhibit A

Trademark Rights

Exhibit A

Transaction Costs

Exhibit A

WARN Act

Section 2.16(j)

Willful Breach

Exhibit A

116

EXHIBIT B

FORM OF COMPANY LOCK-UP AGREEMENT

EXHIBIT C

FORM OF SANTERSUS LOCK-UP AGREEMENT

EXHIBIT D

FORM OF COMPANY VOTING AGREEMENT

EXHIBIT E

FORM OF JOINDER AGREEMENT

EXHIBIT F

SAMPLE NET CASH CALCULATION

EXHIBIT G

SAMPLE EXCHANGE RATIO CALCULATION

Schedule I

Sellers

1. Sergey Avutshenko

2. Andrew Aswani

3. Franklin Corbin III

4. Dexamenos Developpement SA SPF

5. Blaine Dowdle

6. Dmitry Genkin

7. Jacques Hennessy

8. Nicholas Oscar Hodgson

9. Shannon Hope

10. Jonathan Lane

11. Steve Daniel Livshin

12. Svetlana Maguire

13. Medeci Services Limited

14. Moshe Mizrahy

15. Vladimir Nesteruk

16. Norcliffe Nominees Limited

17. Nucleocon Sakartvelo LLC

18. Hugh Osmond

19. Jonathan Craig Quinnell

20. Kirill Surkov

21. Simon Tallett

22. Terumo Americas Holding, Inc.

23. USP Medical LTD

24. Alistair Wardell

25. Aleksandr Zaporoztsev

Schedule II

Company Lock-Up Parties

1. James Parslow

2. Roger Kornberg

3. Alexey Vinogradov

4. CLS Therapeutics Ltd.

Notwithstanding the foregoing, with respect to

any Company Lock-Up Party that is not, and will not be as of immediately following the Closing, a director of the Company or an executive

officer of the Company, the Parties shall terminate the Company Lock-Up Agreement applicable to such Company Lock-Up Party as of the Closing.

To the extent not listed herein as a “Company

Lock-Up Party,” Company shall use reasonable best efforts to cause each Person who is designated a Company Director, but who is

not a Related Party Director, to execute and deliver the Company Lock-Up Agreement prior to the Closing.

SCHEDULE III

Santersus Lock-Up Parties

1. Dmitry Genkin

2. Moshe Mizrahy

3. David Onions

4. James Ladtkow

5. Andrew Aswani

6. Aleksandr Zaporoztsev

7. Kirill Surkov

8. Sergey Avutshenko

9. Vladimir Nesteruk

10. M. Scott Maguire

11. Jacques Hennessy

12. Nucleocon Sakartvelo LLC

Notwithstanding the foregoing, with respect to

any Santersus Lock-Up Party that is not, and will not be as of immediately following the Closing, (i) a director of the Company, (ii)

an executive officer of the Company, or (iii) a beneficial owner of 5% or more of the then-outstanding shares of Company Common Stock,

the Parties shall terminate the Santersus Lock-Up Agreement applicable to such Santersus Lock-Up Party as of the Closing.

To the extent not listed herein as a “Santersus

Lock-Up Party,” Santersus shall use reasonable best efforts to cause each Person who is (i) designated a Santersus Director or (ii)

reasonably expected to beneficially own 5% or more of the outstanding shares of Company Common Stock immediately following the Closing

to execute and deliver the Santersus Lock-Up Agreement prior to the Closing.

SCHEDULE IV

Company Voting Agreement Parties

1. James Parslow

2. Roger Kornberg

3. Alexey Vinogradov

4. Grigory Borisenko

5. Firdaus Jal Dastoor

6. Dmitry Genkin

7. Moshe Mizrahy

8. CLS Therapeutics Ltd.

Schedule 6.22

Termination of Santersus Contracts

1. Shareholders’ Agreement dated September

29, 2025

EX-10.1

Filename: xenetic_ex1001.htm · Sequence: 3

Exhibit 10.1

FORM OF COMPANY STOCKHOLDER VOTING AGREEMENT

This Company Stockholder Voting

Agreement, dated as of ________, 2026 (this “Agreement”), by and between Santersus AG, a Swiss corporation (Aktiengesellschaft)

(“Santersus”), and the Person set forth on Schedule A hereto (“Stockholder”). Capitalized

terms used but not defined in this Agreement shall have the respective meanings ascribed to them in the Share Exchange Agreement.

RECITALS

WHEREAS, concurrently herewith,

(i) Xenetic Biosciences, Inc., a Nevada corporation (“Company”), (ii) Santersus, (iii) the persons listed on Schedule

I thereto (the “Sellers”), and (iv) Santersus, as representative of the Sellers, are entering into a Share Exchange

Agreement (the “Share Exchange Agreement”), pursuant to which, among other things, and subject to the terms and conditions

set forth therein, the Sellers will sell, transfer and convey to the Company, and the Company will purchase from the Sellers, in exchange

for shares of Company Common Stock (as defined below), all of the issued and outstanding capital stock of Santersus (the “Acquisition”);

WHEREAS, as of the date hereof,

Stockholder is the “beneficial owner” (within the meaning of Rule 13d-3 promulgated under the Securities Exchange Act

of 1934, as amended (the “Exchange Act”)) of Company common stock, $0.001 per share (“Company Common Stock”)

as set forth on Schedule A hereto (together with any other equity securities of the Company, including all securities exchangeable,

exercisable or convertible into Company Common Stock, and any securities issued or exchanged with respect to Company Common Stock, and

upon any recapitalization, reclassification, merger, consolidation, spin-off, partial or complete liquidation, stock dividend, split-up

or combination of the securities of the Company or upon any other change in the Company’s capital structure, in each case whether

now owned or hereafter acquired by Stockholder during the period from and including the date hereof through and including the Termination

Date (as defined below), the “Covered Shares”);

WHEREAS, as a condition and

material inducement to Santersus’ willingness to enter into the Share Exchange Agreement and to proceed with the transactions contemplated

thereby, including the Acquisition, Santersus has required Stockholder to enter into this Agreement; and

WHEREAS, Stockholder acknowledges

that Santersus is entering into the Share Exchange Agreement in reliance on the representations, warranties, covenants and other agreements

of Stockholder set forth in this Agreement and would not enter into the Share Exchange Agreement if Stockholder did not enter into this

Agreement.

AGREEMENT

NOW, THEREFORE, in consideration

of the foregoing and the mutual covenants and agreements herein contained, and intending to be legally bound hereby, Santersus and Stockholder

hereby agree as follows:

Agreement to Vote. Subject to the terms and conditions set forth herein, from and after the date hereof, at any meeting

of the stockholders of the Company (whether annual or special and whether or not an adjourned, postponed, reconvened or recessed meeting)

(a “Stockholder Meeting”) however called for the purpose of considering or voting on the Company Stockholder Approval

Matters, or in connection with any written consent of stockholders of the Company in connection with the approval of the Company Stockholder

Approval Matters, Stockholder irrevocably and unconditionally agrees that he, she or it shall, or shall cause the holder of record of

the Covered Shares, on each record date relevant to such a stockholder vote or approval to:

(a)

when a Stockholder Meeting is held, appear at such meeting in person (including via electronic means if the Stockholder Meeting

is held virtually) or represented by a duly executed and non-revoked proxy or otherwise cause the Covered Shares entitled to vote thereat

to be counted as present thereat for the purpose of establishing a quorum, and respond to each request by the Company for written consent,

if any, and

(b)

vote (whether by ballot at a meeting or by proxy), or cause to be voted at such meeting (or validly execute and return and cause

such consent to be granted with respect to), all Covered Shares entitled to vote thereat:

(i)

in favor of the Company Stockholder Approval Matters and any other matters necessary or advisable for consummation of the Acquisition,

the issuance of Company Common Stock in the Acquisition and the other transactions contemplated in the Share Exchange Agreement that is

presented by the Company for a vote of its stockholders (including, but not limited to, any motion by the chairman of the Stockholder

Meeting to adjourn, reconvene, recess or otherwise postpone such meeting), and

(ii)

against approval of any (A) Acquisition Proposal, (B) any proposal made in opposition to, or in competition with, the Share Exchange

Agreement, the consummation of the Acquisition or any of the transactions contemplated by the Share Exchange Agreement or this Agreement,

and (C) any other action, agreement, or transaction that would reasonably be expected to impede, interfere with, delay, postpone, discourage

or adversely affect the Acquisition, the issuance of Company Common Stock in the Acquisition or any of the transactions contemplated by

the Share Exchange Agreement.

(c)

Any vote required to be cast or consent required to be executed pursuant to this Section 1 shall be cast or executed in

accordance with the applicable procedures relating thereto so as to ensure that the Covered Shares are duly counted for purposes of determining

that a quorum is present (if applicable) and for purposes of recording the results of that vote or consent.

Except as permitted under Section

1(b), Stockholder shall retain at all times the right to vote the Covered Shares in Stockholder’s sole discretion and without

any other limitation on those matters other than those set forth in this Section 1 that are at any time or from time to time presented

for consideration to the Company’s stockholders.

Grant of Irrevocable Proxy; Appointment of Proxy.

(a)

Stockholder hereby revokes (or agrees to cause to be revoked) any proxies that Stockholder has heretofore granted with respect

to the Covered Shares. Stockholder hereby grants to, and appoints, Santersus, as Stockholder’s irrevocable (until the Termination

Date) proxy and attorney-in-fact (with full power of substitution) to (i) attend any and all meetings of the Company’s stockholders,

and (ii) vote, express consent or dissent or issue instructions to the record holder to vote the Covered Shares in accordance with the

provisions of Section 1 at any and all meetings of the Company’s stockholders or in connection with any action sought to

be taken by written consent of the Company’s stockholders without a meeting. Stockholder intends this proxy to be irrevocable (until

the Termination Date) (and as such shall survive and not be affected by the death, incapacity, mental illness or insanity of Stockholder,

as applicable) and coupled with an interest and will take such further action or execute such other instruments as may be reasonably necessary

to effectuate the intent of this proxy. Santersus agrees not to exercise the proxy granted herein for any purpose other than the purposes

described in this Agreement.

(b)

The proxy granted in this Section 2 shall automatically expire upon the termination of this Agreement in accordance

with Section 4.

(c)

Stockholder hereby affirms that the proxy set forth in this Section 2 is given in connection with and granted in consideration

of and as an inducement to Santersus to enter into the Share Exchange Agreement and that such proxy is given to secure the obligations

of Stockholder under Section 1.

(d)

With respect to any Covered Shares that are owned beneficially by Stockholder but are not held of record by Stockholder (other

than shares beneficially owned by Stockholder that are held in the name of a bank, broker or nominee), Stockholder shall take all action

reasonably necessary to cause the record holder of such Covered Shares to grant the irrevocable proxy and take all other actions provided

for this in this Section 2 with respect to such Covered Shares.

(e)

Neither Santersus nor any of its designees acting as proxy or attorney-in-fact pursuant to this Section 2 shall incur any

liability to Stockholder for any action taken or omitted to be taken in good faith in connection with the exercise of the proxy granted

under this Section 2, except to the extent such action or omission constitutes fraud or willful misconduct.

No Inconsistent Agreements. Stockholder hereby represents, covenants and agrees that, except as contemplated by this Agreement,

Stockholder: (a) has not entered into, and shall not enter into at any time prior to the Termination Date, any tender, voting or

other similar agreement or arrangement, or voting trust with respect to any Covered Share and (b) has not granted, and shall not

grant at any time prior to the Termination Date, a proxy or power of attorney with respect to any Covered Shares, in either case, which

is inconsistent with Stockholder’s obligations pursuant to this Agreement. Prior to the Termination Date, Stockholder covenants

not to enter into any understanding or agreement with any Person to vote or give instructions with respect to any Covered Share in any

manner inconsistent with Section 1 of this Agreement.

Termination. This Agreement shall terminate automatically without any notice or other action by any Person upon the earliest

of: (a) the Closing, (b) the termination of the Share Exchange Agreement in accordance with its terms, and (c) the mutual written

agreement of the Parties hereto; provided, that Santersus shall not terminate this Agreement without the Company’s prior written

consent (such earliest date being referred to herein as the “Termination Date”); provided, that any liability

incurred by any party hereto as a result of a breach of a term or condition of this Agreement prior to such termination shall survive

the termination of this Agreement and the provisions set forth in Sections 13 through 27 (inclusive) shall survive any termination

of this Agreement.

Representations and Warranties of Stockholder. Stockholder hereby represents and warrants to Santersus as follows:

(a)

Stockholder is the beneficial owner of, and has good and valid title to, the Covered Shares, free and clear of Encumbrances other

than (i) as created by this Agreement, (ii) pursuant to any applicable restrictions on transfer under the Securities Act or state securities

or “blue sky” laws, (iii) subject to any risk of forfeiture or repurchase rights of the Company with respect to any Covered

Shares granted to Stockholder under an employee benefit plan of the Company and (iv) as provided in the Articles of Incorporation or the

bylaws of the Company, as each may be amended. Stockholder has the sole power to direct the record owner to vote and sole power to agree

to all of the matters set forth in this Agreement, in each case with respect to all of such Covered Shares, with no limitations, qualifications

or restrictions on such rights, subject to applicable federal securities laws, state securities or “blue sky” laws, and the

terms of this Agreement. The Covered Shares are not subject to any voting trust agreement or other Contract to which Stockholder is a

party restricting or otherwise relating to the voting or Transfer (as defined below) of the Covered Shares. Stockholder has not appointed

or granted any proxy or power of attorney that is still in effect with respect to any Covered Shares, except as contemplated by this Agreement.

For purposes of this Agreement, “Equity Interests” shall mean any share of capital stock of the Company or any securities

(including debt securities) convertible into, or exchangeable or exercisable for, any such shares of capital stock or any options, warrants,

calls, subscriptions or other rights, convertible securities, agreements or commitments obligating such Person to issue, transfer or sell

any shares of capital stock or other equity interest in the Company.

(b)

Stockholder, if not a natural person, is duly organized or incorporated, validly existing and in good standing under the laws of

the jurisdiction of its organization or incorporation and has all requisite power and authority to execute and deliver this Agreement

and to perform its obligations hereunder. Stockholder, if a natural person, has full legal power and capacity to execute and deliver this

Agreement and to perform Stockholder’s obligations hereunder. The execution, delivery and performance of this Agreement by Stockholder,

the performance by Stockholder of its obligations hereunder and the consummation by Stockholder of the transactions contemplated hereby

have been duly and validly authorized by Stockholder and no other actions or proceedings on the part of Stockholder are necessary to authorize

the execution and delivery by Stockholder of this Agreement, the performance by Stockholder of its obligations hereunder or the consummation

by Stockholder of the transactions contemplated hereby. This Agreement has been duly and validly executed and delivered by Stockholder

and, assuming due authorization, execution and delivery by Santersus, constitutes a legal, valid and binding obligation of Stockholder,

enforceable against Stockholder in accordance with its terms, except as such enforceability may be limited by bankruptcy, insolvency,

reorganization, moratorium, fraudulent conveyance and similar Legal Requirements relating to or affecting creditors’ rights and

remedies generally, or by general equity principles.

(c)

Except for the applicable requirements of the Exchange Act and including the rules and regulations promulgated by the Securities

and Exchange Commission (“SEC”) thereunder), (i) no filing with, and no permit, authorization, consent or approval

of, any Governmental Body is necessary on the part of Stockholder for the execution, delivery and performance of this Agreement by Stockholder

or the consummation by Stockholder of the transactions contemplated hereby and (ii) neither the execution, delivery or performance

of this Agreement by Stockholder nor the consummation by Stockholder of the transactions contemplated hereby nor compliance by Stockholder

with any of the provisions hereof shall (A) if Stockholder is not a natural person, conflict with or violate, any provision of the

organizational documents of Stockholder, (B) result in any breach or violation of, or constitute a default (or an event which, with

notice or lapse of time or both, would become a default) under, or give to others any rights of termination, amendment, acceleration or

cancellation of, or result in the creation of an Encumbrance on such property or asset of Stockholder pursuant to, any Contract to which

Stockholder is a party or by which Stockholder or any property or asset of Stockholder is bound or affected or (C) violate any Legal

Requirement applicable to Stockholder or any of Stockholder’s properties or assets except, in the case of clause (B), for breaches,

violations or defaults that would not, individually or in the aggregate, materially impair the ability of Stockholder to perform its obligations

hereunder.

(d)

There is no action, suit, investigation, complaint or other proceeding pending against Stockholder or, to the knowledge of Stockholder,

any other Person or, to the knowledge of Stockholder, threatened against Stockholder or any other Person that restricts or prohibits (or,

if successful, would restrict or prohibit) the exercise by the Company of its rights under this Agreement or the performance by any party

of its obligations under this Agreement, or that could reasonably be expected to prevent, delay or impair the ability of Stockholder to

perform Stockholders’ obligations hereunder or to consummate the transactions contemplated hereby.

(e)

No broker, finder or investment banker is entitled to any brokerage, finder’s or other fee or commission in connection with

the transactions contemplated by the Share Exchange Agreement or this Agreement based upon arrangements made by or on behalf of Stockholder.

(f)

Stockholder understands and acknowledges that Santersus is entering into the Share Exchange Agreement in reliance upon Stockholder’s

execution and delivery of this Agreement and the representations and warranties of Stockholder contained herein.

(g)

Schedule A hereto sets forth a true, correct and complete list of all shares of Company Common Stock, Company Options, shares

of Company Restricted Stock, and other Equity Interests of the Company owned of record of beneficially by Stockholder and by any Affiliate

of Stockholder that is controlled by Stockholder, in each case of the date of this Agreement.

Certain Covenants of Stockholder. Stockholder, hereby covenants and agrees as follows:

(a)

Prior to the Termination Date, and except as contemplated hereby, Stockholder shall not directly or indirectly (i) tender

into any tender or exchange offer, (ii) sell (constructively or otherwise), transfer, pledge, hypothecate, grant, encumber, assign

or otherwise dispose of (collectively “Transfer”), or enter into any contract, option, agreement or other arrangement

or understanding with respect to the Transfer of any of the Covered Shares, beneficial ownership or voting power thereof or therein (including

by operation of law), or any interest therein, or any economic or voting rights with respect thereto, (iii) grant or permit the grant

of any proxies or powers of attorney, deposit or permit the deposit of any Covered Shares into a voting trust or enter into a voting agreement

or arrangement with respect to any Covered Shares or (iv) take any action that would make any representation or warranty of Stockholder

contained herein untrue or incorrect or have the effect of impeding, preventing or disabling Stockholder from performing its obligations

under this Agreement. Any Transfer in violation of this provision shall be null and void. Stockholder further agrees to authorize and

request Santersus to notify the Company’s transfer agent that there is a stop transfer order with respect to all of the Covered

Shares and that this Agreement places limits on the voting of the Covered Shares. If so requested by Santersus, Stockholder agrees that

any certificates representing Covered Shares shall bear a legend stating that they are subject to this Agreement and to the irrevocable

proxy granted in Section 2(a).

(b)

Notwithstanding anything to the contrary in this Agreement, Stockholder may Transfer any or all of the Covered Shares, in accordance

with applicable Legal Requirements to one or more stockholders of the Company or to an affiliated entity under common control with Stockholder;

provided, however, that a Transfer referred to in this sentence shall be permitted only if, (X) as a precondition to

such Transfer, the transferee agrees in a written document, reasonably satisfactory in form and substance to Santersus, to be bound by

all of the terms of this Agreement to the same extent as Stockholder (a “Joinder”), and (Y) such Transfer is effected

no later than three (3) Business Days prior to the record date for any Stockholder Meeting (or any adjournment or postponement thereof)

and does not delay, hinder or impede (1) the timely voting or consent of the Covered Shares in accordance with Section 1 or

(2) the consummation of the Acquisition. [Notwithstanding the foregoing, the following shall not violate this Section 6: (i)

the exercise of a Company Option (including a net or cashless exercise of a Company Option), any related transfer of shares of Company

Common Stock to the Company for the purpose of paying the exercise price of such options or for paying taxes (including estimated taxes)

due as a result of the exercise of such options or for paying taxes (including estimated taxes) due as a result of the exercise of such

options, or (ii) transfers to the Company in connection with the net settlement of any other equity award that represents the right to

receive in the future shares of Company Common Stock, settled in shares of Company Common Stock, to pay any tax withholding obligations;

provided that, for the avoidance of doubt, the underlying shares of Company Common Stock shall continue to be subject to the restrictions

on Transfer set forth in this Agreement.]1

1Provision

to be included for Stockholders with outstanding equity awards.

Certain Adjustments to Covered Shares. In the event of the acquisition by Stockholder or any of its Affiliates of other

Equity Interests of the Company, (i) Stockholder shall promptly notify Santersus in writing, (ii) the type and number of Covered Shares

shall be adjusted appropriately, (iii) promptly following any such acquisition by an Affiliate (other than a Transfer which shall be governed

by Section 6 above) Stockholder shall cause such Affiliate to duly execute and deliver to Santersus a Joinder, and (iv) this Agreement

and the obligations hereunder shall automatically attach to any additional Equity Interests issued to or acquired by Stockholder or such

Affiliate, as applicable, and shall be deemed to be Covered Shares for all purposes hereunder.

Stockholder Capacity. This Agreement is being entered into by Stockholder solely in its capacity as a stockholder of the

Company, and nothing in this Agreement shall restrict or limit the ability of such Stockholder, any of its Affiliates, or any of their

respective directors, officers or employees who is a director or officer (or equivalent) of the Company or any of its Subsidiaries, as

applicable, to take any action in his or her capacity as a director or officer (or equivalent) of the Company or any of its Subsidiaries.

Waiver of Actions. Stockholder hereby agrees (i) not to, directly or indirectly, commence, or cause to be commenced, any

claim, derivative or otherwise, against Santersus, the Company, or any of their respective successors, or (ii) not to, directly or indirectly,

commence (or cause to be commenced) or participate in, and to take all actions necessary to opt out of, any class in any class action

with respect to, any claim, derivative or otherwise, against Santersus, the Company, or any of their respective successors, in each case

of clause (i) and (ii), (A) challenging the validity of, or seeking to enjoin the operation of, any provision of this Agreement or the

Share Exchange Agreement, (B) alleging a breach of any fiduciary duty of the Company’s board of directors in connection with its

approval of the Share Exchange Agreement or the Acquisition, (C) making any claim with respect to SEC disclosure (or other disclosure

to the Company’s stockholders) in connection with the negotiation, execution or delivery of this Agreement or the Share Exchange

Agreement or the consummation of the Acquisition, or (D) making any aiding and abetting or similar claim against Santersus, the Company,

or any of their respective Affiliates or representatives, in connection with the foregoing; provided, however, that Stockholder may defend

against, contest or settle any such action, claim, suit or cause of action brought against Stockholder that relates solely to Stockholder’s

capacity as a director, officer or a securityholder of the Company.

10.

No Solicitation. Stockholder hereby represents and warrants that Stockholder has read

Section 6.10(a) (Non-Solicitation by Company) of the Share Exchange Agreement and agrees not to engage in any actions prohibited

thereby.

11.

Disclosure. Stockholder hereby (i) authorizes the Company and Santersus to publish and disclose in any announcement or disclosure

required by applicable Legal Requirements in connection with the Acquisition or any transactions contemplated by the Share Exchange Agreement

(A) Stockholder’s identity and ownership of the Covered Shares, (B) the nature of Stockholder’s commitments, arrangements,

understandings and obligations under this Agreement and/or (C) the text of this Agreement, and (ii) agrees as promptly as practicable

to notify the Company and Santersus of any required corrections with respect to any written information supplied by Stockholder specifically

for use in any such disclosure document.

12.

Further Assurances. From time to time, at the request of Santersus and without further consideration, but without being

required to incur any cost or expense, Stockholder shall take such further action as may reasonably be necessary or desirable to carry

out the intent of this Agreement.

13.

Non-Survival of Representations and Warranties. The representations and warranties of Stockholder contained herein shall

not survive the earlier of the Closing and termination of this Agreement pursuant to and in accordance with Section 4 of this Agreement.

14.

Amendment and Modification. This Agreement may not be amended, modified or supplemented in any manner, whether by course

of conduct or otherwise, except by an instrument in writing specifically designated as an amendment hereto, signed on behalf of each party

and the Company and otherwise as expressly set forth herein.

15.

Expenses. All costs and expenses incurred in connection with the transactions contemplated by this Agreement shall be paid

by the party incurring such costs and expenses.

16.

Waiver. No failure or delay of any party in exercising any right or remedy hereunder shall operate as a waiver thereof,

nor shall any single or partial exercise of any such right or power, or any abandonment or discontinuance of steps to enforce such right

or power, or any course of conduct, preclude any other or further exercise thereof or the exercise of any other right or power. The rights

and remedies of the parties hereunder are cumulative and are not exclusive of any rights or remedies which they would otherwise have hereunder.

Any agreement on the part of a party to any such waiver shall be valid only if set forth in a written instrument executed and delivered

by such party; provided, that any waiver by Santersus of the Stockholder’s obligations hereunder shall require the prior written

consent of the Company.

17.

Notices. All notices or other communications required or permitted hereunder shall be in writing and shall be delivered

personally, by email or sent by certified, registered or express air mail, postage prepaid, and shall be deemed given and delivered when

so delivered personally, or if sent by email upon such transmission (provided that no “bounce back” or similar message of

non-delivery is received with respect thereto), or if mailed by overnight courier service guaranteeing next day delivery, one (1) Business

Day after deposited with such service, or if mailed in any other way, then three (3) Business Days after mailing, as follows (or to such

other address or email address as any party hereto shall notify the other parties hereto in accordance with this Section 17), or

to such other address or electronic mail address for a party hereto as shall be specified in a notice given in accordance with this section:

(i)

If to Stockholder, to the address set forth below Stockholder’s name on its signature page.

(ii)

If to Santersus:

Santersus AG

c/o Lex Futura AG

Nüschelerstrasse 45

6001 Zürich

Switzerland

Attn: Scott Maguire

Email:msm@santersus.com

with a copy to (which shall not constitute

notice):

Mintz, Levin, Cohn, Ferris, Glovsky

& Popeo, P.C.

One Financial Center

Boston, MA 02111

Attention: Eric Foster

William C. Hicks

Matthew J. Gardella

Jason S. McCaffrey

Email: efoster@mintz.com

wchicks@mintz.com

mjgardella@mintz.com

jsmccaffrey@mintz.com

18.

Entire Agreement. This Agreement and the Share Exchange Agreement constitute the entire agreement, and supersede all prior

written agreements, arrangements, communications and understandings and all prior and contemporaneous oral agreements, arrangements, communications

and understandings between the parties with respect to the subject matter hereof.

19.

Third-Party Beneficiaries. The Company and each of its successors and assigns is an express third-party beneficiary of,

with rights to enforce its rights under, this Agreement to the same extent as if it was initially a party hereto.

20.

Governing Law. This Agreement and all claims or causes of action based upon, arising out of, or related to this Agreement

or any document, certificate or instrument delivered in connection herewith, or the transactions contemplated by this Agreement, including

the negotiation, execution or performance of this Agreement (whether in contract, tort or otherwise), shall be governed by and construed

in accordance with the law of the State of Nevada, without regard to any applicable conflicts of law principles that would require the

application of the substantive laws of another jurisdiction.

21.

Submission to Jurisdiction. Each party agrees that it will bring any Action or proceeding in respect of any Action arising

out of or relating to this Agreement or the transactions contemplated hereby exclusively in the state courts of the State of Nevada, and

any state appellate court therefrom within the State of Nevada, or, in the event (but only in the event) that such court declines to accept,

or lacks, jurisdiction over such action or proceeding, any federal court within the State of Nevada (the “Chosen Courts”),

and, in connection with claims based upon, arising under or related to this Agreement or the transactions that are the subject of this

Agreement, (i) irrevocably submits to the exclusive jurisdiction of the Chosen Courts, (ii) waives any objection to laying venue in any

such action or proceeding in the Chosen Courts, (iii) waives any objection that the Chosen Courts are an inconvenient forum or do not

have jurisdiction over any party and (iv) agrees that service of process upon such party in any such action or proceeding will be effective

if notice is given in accordance with Section 17.

22.

Waiver of Jury Trial. EACH PARTY ACKNOWLEDGES AND AGREES THAT ANY CONTROVERSY WHICH MAY ARISE UNDER THIS AGREEMENT IS LIKELY

TO INVOLVE COMPLICATED AND DIFFICULT ISSUES, AND THEREFORE EACH SUCH PARTY HEREBY IRREVOCABLY AND UNCONDITIONALLY WAIVES, TO THE EXTENT

PERMITTED BY LAW AT THE TIME OF INSTITUTION OF THE APPLICABLE LITIGATION, ANY RIGHT SUCH PARTY MAY HAVE TO A TRIAL BY JURY IN RESPECT

OF ANY LITIGATION DIRECTLY OR INDIRECTLY ARISING OUT OF OR RELATING TO THIS AGREEMENT OR THE TRANSACTIONS CONTEMPLATED BY THIS AGREEMENT.

EACH PARTY CERTIFIES AND ACKNOWLEDGES THAT: (A) NO REPRESENTATIVE, AGENT OR ATTORNEY OF ANY OTHER PARTY HAS REPRESENTED, EXPRESSLY

OR OTHERWISE, THAT SUCH OTHER PARTY WOULD NOT, IN THE EVENT OF LITIGATION, SEEK TO ENFORCE THE FOREGOING WAIVER, AND (B) EACH PARTY

(I) UNDERSTANDS AND HAS CONSIDERED THE IMPLICATIONS OF THIS WAIVER, (II) MAKES THIS WAIVER VOLUNTARILY, AND (III) EACH PARTY HAS BEEN

INDUCED TO ENTER INTO THIS AGREEMENT BY, AMONG OTHER THINGS, THE MUTUAL WAIVERS AND CERTIFICATIONS IN THIS SECTION 22.

23.

Assignment; Successors. Except as otherwise provided herein, this Agreement may not, without the prior written consent of

all parties hereto, be assigned (except pursuant to the Acquisition), directly or indirectly, by operation of law or otherwise, and any

attempted assignment shall be null and void. Except with respect to the Company, which shall be a third-party beneficiary in accordance

with Section 19 of this Agreement, this Agreement shall be for the sole benefit of the parties hereto and their respective heirs,

successors, permitted assigns and legal representatives and is not intended, nor shall be construed, to give any Person, other than the

parties hereto and their respective heirs, successors, permitted assigns and legal representatives, any legal or equitable right, remedy

or claim hereunder.

24.

Specific Performance. The parties agree that irreparable damage would occur in the event that any of the provisions of this

Agreement were not performed by the parties in accordance with their specific terms or were otherwise breached. It is accordingly agreed

that each party shall be entitled to an injunction or injunctions to prevent breaches or threatened breaches of this Agreement and to

enforce specifically the terms and provisions hereof in any court of competent jurisdiction and that this shall include the right of each

party to cause the other party to fully perform the terms of this Agreement to the fullest extent permissible pursuant to this Agreement

and applicable Legal Requirements and to thereafter cause this Agreement and the transactions contemplated by this Agreement to be consummated

on the terms and subject to the conditions thereto set forth in this Agreement. Such remedies shall be cumulative and not exclusive and

shall be in addition to any other remedies which any party may have under this Agreement or otherwise. The parties hereto agree that the

right of specific performance and other equitable relief is an integral part of the transactions contemplated by this Agreement and without

that right, neither party would have entered into this Agreement. Each of the parties hereby waives (i) any defenses in any action for

specific performance, including the defense that a remedy at law would be adequate and agree not to raise any objections to the availability

of the equitable remedy of specific performance and (ii) any requirement under any Legal Requirement to post a bond or other security

as a prerequisite to obtaining equitable relief.

25.

Severability. The invalidity of any portion of this Agreement by a court of competent jurisdiction shall not affect the

validity, force or effect of the remaining portions of this Agreement. If it is ever held that any restriction hereunder is too broad

to permit enforcement of such restriction to its fullest extent, such restriction shall be enforced to the maximum extent permitted by

applicable Legal Requirements.

26.

Counterparts. This Agreement and any signed agreement or instrument entered into in connection with this Agreement may be

executed in two or more counterparts, each such counterpart being deemed to be an original instrument and all such counterparts together

constituting the same agreement and, to the extent signed and delivered by means of a facsimile machine or telecopy, by email delivery

of a “.pdf” or “.jpg” format data file or by any electronic signature complying with the U.S. federal ESIGN Act

of 2000, shall be treated in all manner and respects as an original agreement or instrument and shall be considered to have the same binding

legal effect as if it were the original signed version thereof delivered in person. No party hereto or to any such agreement or instrument

shall raise the use of a facsimile machine or telecopy, email delivery of a “.pdf” or “.jpg” format data file

or electronic signature complying with the U.S. federal ESIGN Act of 2000 to deliver a signature to this Agreement or any amendment hereto

or the fact that any signature or agreement or instrument was transmitted or communicated through the use of a facsimile machine or telecopy,

email delivery of a “.pdf” or “.jpg” format data file or by any electronic signature complying with the U.S. federal

ESIGN Act of 2000 as a defense to the formation of a contract and each party hereto forever waives any such defense.

27.

No Presumption Against Drafting Party. Each of the parties to this Agreement acknowledges that it has been represented by counsel

in connection with this Agreement and the transactions contemplated by this Agreement. Accordingly, any rule of law or any legal decision

that would require interpretation of any claimed ambiguities in this Agreement against the drafting party has no application and is expressly

waived.

28.

No Ownership Interest. Nothing contained in this Agreement shall be deemed to vest in Santersus any direct or indirect ownership

or incidence of ownership of, or with respect to, any Covered Shares. All rights, ownership and economic benefits of and relating to the

Covered Shares shall remain vested in and belong to Stockholder, and this Agreement shall not confer any right, power or authority upon

Santersus or any other Person (a) to direct Stockholder in the voting of any of the Covered Shares, nor to have authority to manage, direct,

superintend, restrict, regulate, govern or administer any of the policies or operations of the Company, except as otherwise provided herein

with respect to the Covered Shares, or (b) in the performance of any of Stockholder’s duties or responsibilities as a stockholder

of the Company.

[The remainder of this page is intentionally left

blank.]

IN WITNESS WHEREOF, each of

Santersus and Stockholder have caused this Agreement to be duly executed as of the date first written above.

santersus

By: ______________________________________

Name:

Title:

Stockholder:

By:_______________________________________

Name:

Title:

Address for Notices:

__________________________________________

Email: ____________________________________

Schedule A

Covered Shares

Name of Stockholder

Number and Type of Securities

Company Common Stock:

Company Options:

Company Restricted Stock:

Other Equity Interests:

EX-10.2

Filename: xenetic_ex1002.htm · Sequence: 4

Exhibit 10.2

Form of Company Stockholder Lock-Up Agreement

_________, 2026

Xenetic Biosciences, Inc.

945 Concord Street

Framingham, MA 01701

Ladies and Gentlemen:

The undersigned (the “Stockholder”)

understands that Xenetic Biosciences, Inc., a Nevada corporation (the “Company”), has entered into a Share Exchange

Agreement, dated as of September 14, 2026 (the “Share Exchange Agreement”), with Santersus AG, a Swiss corporation

(Aktiengesellschaft) (“Santersus”), the persons listed on Schedule I thereto (the “Sellers”),

and Santersus, as representative of the Sellers, pursuant to which among other things, and subject to the terms and conditions set forth

therein, the Sellers will sell, transfer and convey to the Company, and the Company will purchase from Sellers, in exchange for shares

of Company Common Stock (as defined below), all of the issued and outstanding capital stock of Santersus (the “Acquisition”).

Capitalized terms used but not otherwise defined herein shall have the respective meanings ascribed to such terms in the Share Exchange

Agreement.

As a condition and material

inducement to the willingness of each of the parties to enter into the Share Exchange Agreement and to consummate the Acquisition, and

for other good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, the Stockholder hereby agrees

that the Stockholder will not, subject to the exceptions set forth in this letter agreement, during the period commencing upon the Closing

and ending on the date that is 180 days after the Closing Date (the “Restricted Period”), (a) offer, pledge,

sell, contract to sell, sell any option or contract to purchase, purchase any option or contract to sell, grant any option, right or warrant

to purchase, lend, or otherwise transfer or dispose of, directly or indirectly, any shares of common stock, par value $0.001 per share,

of the Company (“Company Common Stock”) or any securities convertible into or exercisable or exchangeable for

Company Common Stock, including without limitation, Company Common Stock or such other securities which may be deemed to be beneficially

owned by the Stockholder in accordance with the rules and regulations of the U.S. Securities and Exchange Commission and securities of

the Company which may be issued upon exercise of a stock option or warrant or settlement of a restricted stock unit or other equity award

(collectively, “Shares”), (b) enter into any swap, short sale, hedge or other agreement that transfers, in whole

or in part, any of the economic consequences of ownership of the Shares, regardless of whether any such transaction described in clause

(a) or (b) above is to be settled by delivery of Company Common Stock or such other securities, in cash or otherwise, or (c) make any

demand for or exercise any right with respect to the registration of any shares of Company Common Stock or any security convertible into

or exercisable or exchangeable for Company Common Stock, except in connection with the resale registration statement contemplated by the

Share Exchange Agreement or any other registration statement filed by the Company covering the Shares, provided that no sale of Shares

may occur during the Restricted Period except as expressly permitted herein, in each case other than:

(i) transfers of Shares as

bona fide charitable contributions, gifts or donations;

(ii) transfers or dispositions

of Shares to any trust for the direct or indirect benefit of the Stockholder and/or the immediate family of the Stockholder;

(iii) transfers or dispositions

of Shares by will, other testamentary document or intestate succession to the legal representative, heir, beneficiary or a member of the

immediate family of the Stockholder;

(iv) transfers of Shares

to stockholders, direct or indirect affiliates (within the meaning set forth in Rule 405 under the Securities Act), current or former

partners (general or limited), members or managers of the Stockholder, as applicable, or to the estates of any such stockholders, affiliates,

partners, members or managers, or to another corporation, partnership, limited liability company or other business entity that controls,

is controlled by or is under common control with the Stockholder;

(v) transfers that occur

by operation of law pursuant to a court order or settlement agreement related to the distribution of assets in connection with the dissolution

of a marriage or civil union;

(vi) transfers or dispositions

not involving a change in beneficial ownership;

(vii) if the Stockholder

is a trust, transfers or dispositions to any beneficiary of the Stockholder or the estate of any such beneficiary; provided that, in the

case of any transfer or distribution of this clause (vii) such transfer is not for value and each donee, heir, beneficiary or other transferee

or distributee shall sign and deliver to the Company a lock-up agreement in the form of this letter agreement with respect to the shares

of Company Common Stock or such other securities that have been transferred or distributed;

(viii) transfers pursuant

to a bona fide third party tender offer, merger, consolidation or other similar transaction made to all holders of the Company’s

capital stock involving a change of control of the Company, provided that in the event that such tender offer, merger, consolidation

or other such transaction is not completed, the Shares shall remain subject to the restrictions contained in this letter agreement;

(ix) the exercise of an option

to purchase shares of Company Common Stock (including a net or cashless exercise of an option to purchase shares of Company Common Stock

), and any related transfer of shares of Company Common Stock to the Company for the purpose of paying the exercise price of such options

or for paying taxes (including estimated taxes) due as a result of the exercise of such options or for paying taxes (including estimated

taxes) due as a result of the exercise of such options; provided that, for the avoidance of doubt, the underlying shares

of Company Common Stock shall continue to be subject to the restrictions on transfer set forth in this letter agreement;

(x) transfers

to the Company in connection with the net settlement of any other equity award that represents the right to receive in the future shares

of Company Common Stock, settled in shares of Company Common Stock, to pay any tax withholding obligations; provided that,

for the avoidance of doubt, the underlying shares of Company Common Stock shall continue to be subject to the restrictions on transfer

set forth in this letter agreement;

provided, that in each case of clauses

(ii)-(vii), (a) other than with respect to clause (iv), no filing by any party (including any donor, donee, transferor or transferee,

distributor or distributee) under the Exchange Act or other public announcement shall be required or shall be made voluntarily in connection

with such transfer or distribution (other than filings made in respect of involuntary transfers or dispositions or a filing on a Form

5 made after the expiration of the Restricted Period), (b) other than with respect to clause (iv), any such transfer or distribution shall

not involve a disposition for value, and (c) the transferee or donee agrees in writing to be bound by the terms and conditions of this

letter agreement and either the Stockholder or the transferee or donee provides the Company with a copy of such agreement promptly upon

consummation of any such transfer; provided further, that in the case of clause (ix) and (x), filings under Section 16(a)

of the Exchange Act shall only be permissible if such filing clearly indicates in the footnotes thereto that the filing relates to securities

being sold to generate net proceeds up to the total amount of taxes or estimated taxes (as applicable) that become due as a result of

the vesting and/or settlement of Company equity awards. For purposes of this letter agreement, “immediate family” shall mean

any relationship by blood, marriage or adoption, not more remote than first cousin.

Notwithstanding the restrictions

imposed by this letter agreement, the Stockholder may (a) exercise an option or warrant to purchase Shares or settle a restricted stock

unit or other equity award (including a net or cashless exercise of such option or warrant provided the Shares are transferred

to the Company and not sold on the open market) and provided further, that the underlying Shares shall continue to be subject

to the restrictions on transfer set forth in this letter agreement, (b) transfer Shares to the Company to cover tax withholding obligations

of the Stockholder in connection with the vesting, settlement or exercise of such options, warrants, restricted stock units or other equity

awards, as applicable, (c) establish a trading plan pursuant to Rule 10b5-1 under the Exchange Act (“10b5-1 Plan”)

for the transfer of Shares, provided that such plan does not provide for any transfers of Shares during the Restricted Period

(except as provided in clauses (ix) and (x) above) and, provided further, that, no filing under the Exchange Act or other

public announcement shall be required or shall be made voluntarily in connection with the establishment of such a plan, (d) transfer Shares

to the Company pursuant to arrangements under which the Company has the option to repurchase such Shares, or (e) transfer or dispose of

Shares acquired on the open market following the Closing.

Any attempted transfer in

violation of this letter agreement will be of no effect and null and void, regardless of whether the purported transferee has any actual

or constructive knowledge of the transfer restrictions set forth in this letter agreement, and will not be recorded on the stock transfer

books of the Company. In order to ensure compliance with the restrictions referred to herein, the Stockholder agrees that the Company

and/or any duly appointed transfer agent may issue appropriate “stop transfer” certificates or instructions. The Company may

cause the legend set forth below, or a legend substantially equivalent thereto, to be placed upon any certificate(s) or other documents

or instruments evidencing ownership of the Shares:

THE SHARES REPRESENTED BY THIS CERTIFICATE

ARE SUBJECT TO AND MAY ONLY BE TRANSFERRED IN COMPLIANCE WITH A LOCK-UP AGREEMENT, A COPY OF WHICH IS ON FILE AT THE PRINCIPAL OFFICE

OF THE COMPANY.

The Stockholder hereby represents

and warrants that the Stockholder has full power and authority to enter into this letter agreement. All authority conferred or agreed

to be conferred and any obligations of the Stockholder under this letter agreement will be binding upon the successors, assigns, heirs

or personal representatives of the Stockholder.

If, during the Restricted

Period, the Stockholder ceases to beneficially own 5% or more of the then-outstanding shares of Company Common Stock and, at such time,

is neither a director nor executive officer of the Company, the parties shall terminate this letter agreement effective as of the time

such Stockholder’s beneficial ownership falls below 5% (a “5% Termination”). The Stockholder will promptly

notify the Company in writing of any event or transaction that causes or may cause it to cease to beneficially own 5% or more of the then-outstanding

shares of Company Common Stock and shall deliver with such notice a certification signed by such Stockholder stating its beneficial ownership

and the date on which its beneficial ownership fell below 5%, together with reasonable supporting detail. The Company may request reasonable

supporting information to verify the notice and certification, and the Stockholder shall promptly provide the requested information.

Such termination shall become

operative for purposes of releasing the Shares only after the Company has promptly verified the applicable ownership information and delivered

written confirmation of the termination, which confirmation shall not be unreasonably withheld or delayed, and in any event shall be provided

within three (3) Business Days. Until such written confirmation is delivered, the restrictions set forth in this letter agreement and

any stop-transfer instructions shall remain in full force and effect, and any attempted transfer before such confirmation shall remain

subject to such restrictions and be of no effect and null and void to the extent provided herein. Promptly after delivering such written

confirmation, the Company shall instruct its transfer agent to remove the contractual restrictions and any related stop-transfer instructions

only from the Shares held by the applicable Shareholder, subject to applicable securities laws and any other restrictions. Nothing in

this paragraph shall release, waive or impair any rights or remedies accrued before such written confirmation, including any rights or

remedies arising from a prior breach.

Without limiting the permitted

transfers set forth herein, no transfer or other disposition among affiliates or members of any group shall be used to avoid or circumvent

the 5% Termination, the verification requirements or the continued effectiveness of the restrictions pending written confirmation, and

any holdings required to be aggregated under this paragraph shall remain aggregated notwithstanding any such transfer or disposition.

In the event that during

the Restricted Period any holder of the Company’s securities that is subject to a substantially similar agreement entered into by

such holder, other than the Stockholder, is permitted by the Company to sell or otherwise transfer or dispose of shares of Company Common

Stock for value other than as permitted by this or a substantially similar agreement entered into by such holder, the same percentage

of shares of Company Common Stock held by the Stockholder shall be immediately and fully released on the same terms from any remaining

restrictions set forth herein; (the “Pro-Rata Release”); provided, however, that such

Pro-Rata Release shall not be applied unless and until permission has been granted by the Company to an equity holder or equity holders

to sell or otherwise transfer or dispose of all or a portion of such equity holders shares of Company Common Stock in an aggregate amount

in excess of 1% of the number of shares of Company Common Stock subject to a substantially similar agreement. In the event of any Pro-Rata

Release, the Company shall promptly (and in any event within two (2) Business Days of such release) inform each relevant holder of Company

Common Stock of the terms of such Pro-Rata Release.

Upon the release of any

Shares from this letter agreement, the Company will cooperate with the Stockholder to facilitate the timely preparation and delivery of

certificates or the establishment of book entry positions at the Company’s transfer agent representing the Shares without the restrictive

legend above and the withdrawal of any stop transfer instructions at the Company’s transfer agent.

The Stockholder understands

that each of Santersus and the Company is relying upon this letter agreement in proceeding toward consummation of the Acquisition. The

Stockholder further understands that this letter agreement is irrevocable and is binding upon the Stockholder’s heirs, legal representatives,

successors and assigns.

Any and all remedies herein

expressly conferred upon Santersus or the Company will be deemed cumulative with and not exclusive of any other remedy conferred hereby,

or by law or equity, and the exercise by Santersus or the Company of any one remedy will not preclude the exercise of any other remedy.

The undersigned agrees that irreparable damage for which monetary damages, even if available, would not be an adequate remedy, would occur

to Santersus and/or the Company in the event that any provision of this letter agreement was not performed in accordance with its specific

terms or were otherwise breached. It is accordingly agreed that the Company and/or Santersus shall be entitled to an injunction or injunctions

to prevent breaches of this letter agreement and to enforce specifically the terms and provisions hereof in any court of the United States

or any state having jurisdiction, this being in addition to any other remedy to which the Company or Santersus is entitled at law or in

equity, and the undersigned waives any bond, surety or other security that might be required of the Company or Santersus with respect

thereto. Each of the parties further agrees that it will not oppose the granting of an injunction, specific performance or other equitable

relief on the basis that any other party has an adequate remedy at law or that any award of specific performance is not an appropriate

remedy for any reason at law or in equity.

This letter agreement and

any claim, controversy or dispute arising under or related to this letter agreement shall be governed by and construed in accordance with

the laws of the State of Nevada, without regard to the conflict of Laws principles thereof. In any action or proceeding between any of

the parties arising out of or relating to this letter agreement, each of the parties: (i) irrevocably and unconditionally consents and

submits to the exclusive jurisdiction and venue of the state courts of the State of Nevada, and any state appellate court therefore within

the State of Nevada, or, in the event (but only in the event) that such court declines to accept, or lacks, jurisdiction over such action

or proceeding, any federal court within the State of Nevada, (ii) agrees that all claims in respect of such action or proceeding shall

be heard and determined exclusively in accordance with foregoing clause (i) of this paragraph, (iii) waives any objection to laying venue

in any such action or proceeding in such courts, (iv) waives any objection that such courts are an inconvenient forum or do not have jurisdiction

over any party and (v) irrevocably and unconditionally waives the right to trial by jury. This letter agreement constitutes the entire

agreement between the parties to this letter agreement and supersedes all other prior agreements, arrangements and understandings, both

written and oral, among the parties with respect to the subject matter hereof.

The Stockholder understands

that if the Share Exchange Agreement is terminated in accordance with its terms, the Stockholder will be released from all obligations

under this letter agreement.

This letter agreement may

be executed by electronic (i.e., PDF) transmission, which is deemed an original.

No amendment, waiver or

modification of this Agreement shall be effective unless in writing and signed by the Company and the Stockholder.

[Signature Page Follows]

Very truly yours,

Print Name of Stockholder:

Signature (for individuals):

Signature (for entities):

By:

Name:

Title:

Accepted and Agreed:

Xenetic Biosciences, Inc.

By:____________________

Name:

Title:

EX-10.3

Filename: xenetic_ex1003.htm · Sequence: 5

Exhibit 10.3

Form of Santersus Stockholder Lock-Up Agreement