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Form 8-K

sec.gov

8-K — OptimizeRx Corp

Accession: 0001213900-26-041604

Filed: 2026-04-09

Period: 2026-04-03

CIK: 0001448431

SIC: 7389 (SERVICES-BUSINESS SERVICES, NEC)

Item: Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers

Item: Regulation FD Disclosure

Item: Financial Statements and Exhibits

Documents

8-K — ea0285473-8k_optimize.htm (Primary)

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UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, D.C. 20549

FORM 8-K

CURRENT REPORT

Pursuant to Section 13 or 15(d) of

the Securities Exchange Act of 1934

Date of Report (Date of Earliest Event Reported): April

3, 2026

OptimizeRx Corporation

(Exact name of registrant as specified in charter)

Nevada

001-38543

26-1265381

(State or other jurisdiction

of incorporation)

(Commission File Number)

(IRS Employer

Identification No.)

260 Charles Street, Suite 302

Waltham, MA 02453

(Address of principal executive offices)

Registrant’s telephone number, including

area code: 248.651.6568

Not

Applicable

(Former name or former address, if changed since

last report)

Check the appropriate box below if the Form 8-K filing is intended

to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (see General Instruction A.2.

below):

Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to Section 12(b) of the Act:

Title of each class

Trading Symbol(s)

Name of each exchange on which registered

Common Stock, $0.001 Par Value

OPRX

The Nasdaq Capital Market

Indicate by check mark whether the registrant is an emerging growth

company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange

Act of 1934 (§240.12b-2 of this chapter).

Emerging growth company ☐

If an emerging growth company, indicate by check mark if the registrant

has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant

to Section 13(a) of the Exchange Act. ☐

Item 5.02 Departure of Directors or Certain Officers; Election of

Directors; Appointment of Certain Officers; Compensatory Arrangement of Certain Officers.

On April 3, 2026, the Board of Directors (the “Board”)

of OptimizeRx Corporation (the “Company”), upon the recommendation of the Board’s Nominating & Governance Committee,

appointed Mary Varghese Presti to serve as a director of the Company until the date of the Company’s 2026 annual meeting of stockholders

and until her successor is elected and qualified, except in the event of her earlier death, resignation or removal. The appointment of

Ms. Varghese Presti as an independent director is in furtherance of the Company’s ongoing process to refresh and expand its Board.

In connection with Ms. Varghese Presti’s appointment to the Board, the Board expanded the size of the Board to seven members from

its current six members. The Board also appointed Ms. Varghese Presti to serve as a member of the Audit Committee.

As a non-employee director, Ms. Varghese Presti will participate in

the Company’s previously disclosed non-employee director compensation program, which includes, among other things, an annual cash

retainer of $45,000, an annual equity grant with a grant date value of approximately $175,000, and an additional annual cash retainer

of $10,000 for serving as a member of the Audit Committee.

Item 7.01 Regulation FD Disclosure.

On April 8, 2026, the Company issued a press release announcing the

appointment of Ms. Varghese Presti to its Board. A copy of the press release is furnished with this Current Report on Form 8-K as Exhibit

99.1 and is incorporated herein by reference.

The information in this Item 7.01 and Exhibit 99.1 attached hereto

is furnished and shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended

(the “Exchange Act”), or otherwise subject to the liabilities of that section, nor shall such information be deemed incorporated

by reference into any filing under the Securities Act of 1933, as amended, or the Exchange Act, except as expressly set forth by specific

reference in such filing.

Item 9.01. Financial Statements and Exhibits.

Exhibit Number

Description

99.1

Press release, dated April 8, 2026

104

Cover Page Interactive Data File (embedded within the Inline XBRL document).

1

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934,

the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

OPTIMIZERX CORPORATION

Date: April 8, 2026

By:

/s/ Marion Odence-Ford

Name:

Marion Odence-Ford

Title:

Chief Legal & Administrative Officer

2

EX-99.1 — PRESS RELEASE, DATED APRIL 8, 2026

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Exhibit 99.1

OptimizeRx Appoints Mary Varghese Presti

to Board of Directors

Microsoft Health & Life Sciences COO brings

expertise in scaling healthcare platforms, commercializing new technologies, and driving operational efficiency

WALTHAM, MA – April 8, 2026 (GLOBE NEWSWIRE)

– OptimizeRx Corp. (the “Company”) (Nasdaq: OPRX), a leading provider of healthcare solutions helping life sciences

companies reach and engage healthcare professionals (HCPs) and patients, today announced the appointment of Mary Varghese Presti to its

Board of Directors. The appointment of Varghese Presti as an independent director is in furtherance of the Company’s ongoing process

to refresh and expand its Board of Directors.

Varghese Presti brings more than 25 years of experience

at the intersection of healthcare, life sciences, and technology, with a track record of building and scaling platforms that translate

innovation into real-world impact. She currently serves as Corporate Vice President and Chief Operating Officer of Microsoft’s Health

& Life Sciences organization, where she leads operational strategy and execution for a global, high-growth business.

At Microsoft, Varghese Presti plays a central

role in advancing the company’s healthcare strategy during a period of rapid transformation driven by AI. She has helped operationalize

next-generation, AI-powered capabilities, including clinical and agentic technologies, that are reshaping how care is delivered, how workflows

are managed, and how health systems scale. Her work focuses on enabling healthcare organizations to increase clinical capacity, improve

decision-making, and deliver more connected, data-driven care.

Varghese Presti has held leadership roles across

some of the most influential organizations in healthcare and technology, including Microsoft, Nuance, IBM Watson Health, athenahealth,

and Pfizer. Her career uniquely spans care delivery, health policy, life sciences, and enterprise

technology, giving her a cross-sector perspective on how innovation moves from concept to adoption at scale.

She brings deep experience across the M&A

lifecycle, including strategic diligence, post-acquisition integration, and portfolio scaling. At Microsoft, she has been closely involved

in integration efforts following the acquisition of Nuance, helping align product, operational, and commercial capabilities to scale the

combined platform. Previously, at IBM Watson Health, she led a life sciences portfolio built through multiple acquisitions and played

a key role in diligence efforts related to IBM’s divestiture of Watson Health to private equity ownership.

Across these roles, she has consistently led efforts

to modernize product portfolios, build new businesses, and drive operational and commercial transformation in complex, regulated environments.

“Mary’s experience from deal strategy

through post transaction integration, scaling platforms, commercializing innovation, and driving operational rigor at some of the world’s

leading healthcare and technology companies aligns directly with our strategy,” said Steve Silvestro, Chief Executive Officer of

OptimizeRx. “As we continue to evolve OptimizeRx into a more integrated, product-led platform with increasing recurring and subscription-based

revenue, her perspective will be critical in helping us accelerate growth, expand our product portfolio, and deliver long-term shareholder

value.”

“I’m excited to join OptimizeRx at

a time when both healthcare and technology are evolving so quickly,” said Varghese Presti. “There is real opportunity to rethink

how data, engagement, and intelligences come together to better support clinicians and patients. I look forward to working with the Board

and leadership team to help scale the platform and build solutions that deliver meaningful impact across the healthcare ecosystem.”

Varghese Presti began her career as a pediatric

nurse at Johns Hopkins, an experience that continues to shape her approach to healthcare innovation,

grounded in the realities of care delivery and the importance of maintaining the human connection at the center of care.

About OptimizeRx

OptimizeRx is a leading healthcare technology

company that’s redefining how life science brands connect with patients and healthcare providers. Our platform combines innovative

artificial intelligence (AI)-driven tools like the Dynamic Audience Activation Platform (DAAP) and Micro-Neighborhood Targeting (MNT)

to deliver timely, relevant, and hyper-local engagement. By bridging the gap between HCP and DTC strategies, we empower brands to create

synchronized marketing solutions that drive faster treatment decisions and improved patient outcomes.

Our commitment to privacy-safe, patient-centric

technology ensures that every interaction is designed to make a meaningful impact, delivering life-changing therapies to the right patients

at the right time. Headquartered in Waltham, Massachusetts, OptimizeRx partners with some of the world’s leading pharmaceutical

and life sciences companies to transform the healthcare landscape and create a healthier future for all.

For more information, follow the Company on X,

LinkedIn or visit www.optimizerx.com.

Important Cautions Regarding Forward-Looking

Statements

This press release contains forward-looking statements

within the meaning of the Private Securities Litigation Reform Act of 1995. Words such as “anticipates”, “believes”,

“estimates”, “expects”, “forecasts”, “intends”, “plans”, “projects”,

“targets", “designed”, “could”, “may”, “should”, “will” or other

similar words and expressions are intended to identify these forward-looking statements. All statements in this press release that reflect

the Company's expectations, assumptions, projections, beliefs or opinions about the future, other than statements of historical fact,

are forward-looking statements, including, without limitation, statements relating to OptimizeRx’s appointment of a new Board member,

and the Company’s plans to scale platforms, commercialize innovation, and drive operational rigor, to evolve into a more integrated,

product-led platform with increasing recurring and subscription-based revenue, to accelerate growth, expand its product portfolio, and

deliver long-term shareholder value, and to build solutions that deliver meaningful impact across the healthcare ecosystem. Because such

statements are subject to risks and uncertainties, actual results may differ materially from those expressed or implied by such forward-looking

statements. These forward-looking statements are based upon the Company’s current expectations and involve assumptions regarding

the Company’s business, the economy, and other future conditions that may never materialize or may prove to be incorrect. Forward-looking

statements are inherently subject to risks and uncertainties, some of which cannot be predicted, or quantified. Actual results and the

timing of events could differ materially from those anticipated in such forward-looking statements as a result of various risks and uncertainties

including, but not limited to, the Company’s success with the appointment of a new Board member, the effect of government regulation,

seasonal trends, dependence on a concentrated group of customers, cybersecurity incidents that could disrupt operations, the ability to

keep pace with growing and evolving technology, the ability to maintain contracts with electronic prescription platforms and electronic

health records networks, competition, and other factors discussed in the Company’s Annual Report on Form 10-K for the year ended

December 31, 2025, and in other filings the Company has made and may make with the SEC in the future. One should not place undue reliance

on these forward-looking statements, which speak only as of the date on which they were made. The Company undertakes no obligation to

update such statements to reflect events that occur or circumstances that exist after the date on which they were made, except as may

be required by law.

OptimizeRx Investor Relations Contact

Andy D’Silva, Chief Business Officer

adsilva@optimizerx.com

OptimizeRx Marketing Contact

Jennifer Dinkel, VP, Marketing

jdinkel@optimizerx.com

Press Inquiries

Matter Communications

optimizerx@matternow.com

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