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Form 8-K

sec.gov

8-K — SmartKem, Inc.

Accession: 0001104659-26-099673

Filed: 2026-08-21

Period: 2026-08-20

CIK: 0001817760

SIC: 3674 (SEMICONDUCTORS & RELATED DEVICES)

Item: Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year

Item: Financial Statements and Exhibits

Documents

8-K — tm2623749d1_8k.htm (Primary)

EX-3.1 — EXHIBIT 3.1 (tm2623749d1_ex3-1.htm)

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UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, DC 20549

FORM 8-K

CURRENT REPORT

Pursuant to Section 13 or 15(d) of

the Securities Exchange Act of 1934

Date of Report (Date of earliest event

reported): August 20, 2026

SmartKem, Inc.

(Exact name of registrant as specified in its charter)

Delaware

001-42115

85-1083654

(State or other jurisdiction

of incorporation)

(Commission

File Number)

(IRS Employer

Identification No.)

3 Germay Drive, Unit 4 #1029

Wilmington, DE, 19804

(Address of principal executive offices, including

zip code)

N/A

(Former name or former address, if changed since

last report)

Check the appropriate box below if the Form 8-K filing is intended

to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

¨

Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

¨

Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

¨

Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

¨

Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to

Section 12(b) of the Act:

Title of each class

Trading Symbol(s)

Name of exchange on which

registered

Common Stock, par value

$0.0001 per share

SMTK

The Nasdaq Stock Market LLC

Indicate by check mark whether the registrant is an emerging growth

company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b - 2 of the Securities Exchange

Act of 1934 (§240.12b - 2 of this chapter).

Emerging growth

company x

If an emerging

growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any

new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ¨

Item 5.03. Amendments to Articles of Incorporation or Bylaws; Changes

in Fiscal Year.

On August 20, 2026, SmartKem, Inc. (the “Company”)

filed a Certificate of Amendment to its Certificate of Incorporation with the Secretary of State of the State of Delaware (the “Certificate

of Amendment”) to effectuate a reverse stock split (the “Reverse Stock Split”) of its issued and outstanding

shares of its common stock, par value $0.0001 per share (“Common Stock”), on a 1-for-50 basis. The Certificate of Amendment

became effective at 5:00 p.m. (Eastern Time) on August 20, 2026 (the “Effective Time”). As of the Effective Time, every

fifty shares of issued and outstanding Common Stock were converted into one share of Common Stock. No fractional shares were issued in

connection with the Reverse Stock Split. Instead, any fractional share resulting from the Reverse Split will be rounded up to the next

whole share. The Company’s transfer agent, Equiniti Trust Company, LLC acted as the exchange agent for the Reverse Stock Split.

The Reverse Stock Split did not alter the par value of the Company’s Common Stock. The Reverse Stock Split did not impact the authorized

number of shares of Common Stock. In addition, pursuant to their terms, a proportionate adjustment was made to the per share exercise

price and number of shares issuable under all of the Company’s outstanding stock options and warrants to purchase shares of Common

Stock, and the number of shares authorized and reserved for issuance pursuant to the Company’s equity incentive plan will be reduced

proportionately.

A copy of the Certificate of Amendment is attached

as Exhibit 3.1 to this Current Report on Form 8-K and is incorporated herein by reference. The foregoing description of the Reverse Stock

Split does not purport to be complete and is qualified in its entirety by reference to such exhibit, which is incorporated by reference.

Item 9.01. Financial Statements and Exhibits.

(d) Exhibits.

Exhibits

Description

3.1

Certificate of Amendment of Certificate of Incorporation

104

Cover Page Interactive Data File (Embedded within the Inline XBRL document)

Signature

Pursuant to the requirements of the Securities Exchange Act of 1934,

the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

SMARTKEM, INC.

Dated: August 21, 2026

By:

/s/ Barbra

C. Keck

Barbra C. Keck

Chief Financial Officer

EX-3.1 — EXHIBIT 3.1

EX-3.1

Filename: tm2623749d1_ex3-1.htm · Sequence: 2

Exhibit 3.1

CERTIFICATE OF AMENDMENT TO THE

AMENDED AND RESTATED

CERTIFICATE OF INCORPORATION

OF SMARTKEM, INC.

SmartKem, Inc. (the

“Corporation”), a corporation organized and existing under and by virtue of the General Corporation Law of the State

of Delaware, does hereby certify as follows:

FIRST: That a resolution

was duly adopted on July 24, 2026, by the Board of Directors of the Corporation pursuant to Section 242 of the General Corporation

Law of the State of Delaware setting forth an amendment to the Amended and Restated Certificate of Incorporation of the Corporation and

declaring said amendment to be advisable. The stockholders of the Corporation duly approved said proposed amendment at the annual meeting

of stockholders held on June 23, 2026, in accordance with Section 242 of the General Corporation Law of the State of Delaware.

The proposed amendment is set forth as follows:

Article IV

of the Amended and Restated Certificate of Incorporation of the Corporation be and hereby is amended by adding the following after the

first paragraph of Section A of Article IV:

“Upon effectiveness

(“Effective Time”) of this amendment to the Certificate of Incorporation, a one-for-50 reverse stock split (the “Reverse

Stock Split”) of the Corporation’s Common Stock shall become effective, pursuant to which each 50 shares of Common Stock

outstanding and held of record by each stockholder of the Corporation and each share of Common Stock held in treasury by the Corporation

immediately prior to the Effective Time (“Old Common Stock”) shall automatically, and without any action by

the holder thereof, be reclassified and combined into one (1) validly issued, fully paid and non-assessable share of Common Stock

(“New Common Stock”), subject to the treatment of fractional interests as described below and with no corresponding

reduction in the number of authorized shares of Common Stock. The Reverse Stock Split shall also apply to any outstanding securities or

rights convertible into, or exchangeable or exercisable for, Old Common Stock and all references to such Old Common Stock in agreements,

arrangements, documents and plans relating thereto or any option or right to purchase or acquire shares of Old Common Stock shall be deemed

to be references to the New Common Stock or options or rights to purchase or acquire shares of New Common Stock, as the case may be, after

giving effect to the Reverse Stock Split.

No fractional shares

of Common Stock will be issued in connection with the Reverse Stock Split. If, upon aggregating all of the Common Stock held by a holder

of Common Stock immediately following the Reverse Stock Split a holder of Common Stock would otherwise be entitled to a fractional share

of Common Stock, the Corporation shall issue to such holder such fractions of a share of Common Stock as are necessary to round the number

of shares of Common Stock held by such holder up to the nearest whole share.

Each holder of

record of a certificate or certificates for one or more shares of the Old Common Stock shall be entitled to receive as soon as practicable,

upon surrender of such certificate, a certificate or certificates representing the largest whole number of shares of New Common Stock

to which such holder shall be entitled pursuant to the provisions of the immediately preceding paragraphs. Each stock certificate that,

immediately prior to the Effective Time, represented shares of Old Common Stock that were issued and outstanding immediately prior to

the Effective Time shall, from and after the Effective Time, automatically and without the necessity of presenting the same for exchange,

represent that number of whole shares of New Common Stock after the Effective Time into which the shares formerly represented by such

certificate have been reclassified, subject to adjustment for fractional shares as described above.

SECOND: That said amendment

will have an Effective Time of 5:00 PM, Eastern Time, on August 20, 2026.

IN WITNESS WHEREOF, the undersigned

has executed this Amendment as evidence of its adoption by the Board of Directors of the Corporation on the date set forth above.

SMARTKEM, INC.

By: /s/ Ian Jenks

Name:

Ian Jenks

Title:

Chief Executive Officer

Date:

August 20, 2026

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