PSMA-Targeted Therapy Market Set to Expand by 2034 on Strong Pipeline and Increasing Diagnosis Rates | DelveInsight
The PSMA-targeted therapy market is expected to grow strongly, fueled by higher prostate cancer diagnosis rates, improved awareness of PSMA-based treatments, and an expanding clinical trial landscape of therapies such as Lantheus' Lu-177-PNT2002/[Lu-177]-PSMA-I&T/PNT-2002), Telix Pharmaceuticals' 177Lu-DOTA-rosopatamab/TLX591, and others.
LAS VEGAS, Jan. 20, 2026 /PRNewswire/ -- DelveInsight's PSMA-targeted Therapy Market Size, Target Population, Competitive Landscape & Market Forecast report includes a comprehensive understanding of current treatment practices, addressable patient population. The report also provides insights into the emerging PSMA-targeted therapy, market share of individual therapies, and current and forecasted market size from 2020 to 2034, segmented into leading markets (the US, EU4, UK, and Japan).
Key Takeaways from the PSMA-targeted Therapy Market Report
Discover what is the projected global PSMA-targeted therapy market size by 2034 @ https://www.delveinsight.com/sample-request/psma-targeted-therapy-market-forecast?utm_source=cision&utm_medium=pressrelease&utm_campaign=spr
Key Factors Driving the PSMA-targeted Therapy Market
PSMA-targeted Therapy Market Analysis
Learn more about the PSMA-targeted therapy @ PSMA-targeted Therapy Analysis
PSMA-targeted Therapy Competitive Landscape
Lantheus (Lu-177-PNT2002), Telix Pharmaceuticals (177Lu-DOTA-rosopatamab tetraxetan (TLX591)), and several other companies are actively involved in developing and producing PSMA-targeted therapies, which have the potential to significantly impact and expand the PSMA-targeted therapy market.
Lantheus' PNT2002 is a small-molecule radioligand therapy being developed to treat mCRPC. The therapy targets PSMA by pairing a PSMA-selective ligand, PSMA-I&T, with no-carrier-added lutetium-177, a beta-emitting radioisotope. This design enables selective binding to PSMA-expressing tumor cells and delivers localized radiation to malignant tissue while limiting exposure to healthy cells.
PNT2002 is currently being evaluated in a Phase III clinical trial that compares its efficacy with the current standard of care in pre-chemotherapy mCRPC patients who have progressed following treatment with at least one androgen receptor pathway inhibitor.
¹⁷⁷Lu-DOTA-rosopatamab tetraxetan (TLX591) is a PSMA-targeted radioimmunotherapy developed by Telix Pharmaceuticals. It consists of rosopatamab, a humanized IgG1 monoclonal antibody, conjugated to the beta-emitting radioisotope lutetium-177 using the DOTA-NHS ester chelator. Also referred to as TLX591, the therapy delivers cytotoxic radiation specifically to PSMA-expressing prostate cancer cells, enabling focused tumor irradiation while sparing surrounding normal tissue. Clinical studies of TLX591 have reported encouraging outcomes in advanced prostate cancer, including mCRPC, with evidence of tumor burden reduction and improvements in progression-free survival.
The anticipated launch of these emerging therapies are poised to transform the PSMA-targeted therapy market landscape in the coming years. As these cutting-edge therapies continue to mature and gain regulatory approval, they are expected to reshape the PSMA-targeted therapy market landscape, offering new standards of care and unlocking opportunities for medical innovation and economic growth.
To know more about who are the leading PSMA-targeted therapy developers, visit @ PSMA-targeted Therapy Treatment
What is PSMA-targeted Therapy?
PSMA-targeted therapy is a precision treatment approach primarily used in prostate cancer that focuses on prostate-specific membrane antigen (PSMA), a cell-surface protein highly overexpressed on prostate cancer cells, especially in advanced and metastatic disease. These therapies use PSMA as a biological "address label" to selectively deliver diagnostic agents or therapeutic payloads, such as radioligands, antibody-drug conjugates, or small-molecule inhibitors, directly to tumor cells while sparing most normal tissues. By binding specifically to PSMA, the treatment is internalized into cancer cells, enabling targeted tumor cell killing, improved imaging accuracy, and reduced systemic toxicity compared with conventional therapies. PSMA-targeted therapy has become a cornerstone of theranostics in prostate cancer, integrating diagnosis and treatment into a single, personalized strategy.
PSMA-targeted Therapy Epidemiology Segmentation
The PSMA-targeted therapy market report is a comprehensive and specialized analysis, offering in-depth epidemiological insights for the study period 2020–2034 across the leading markets. The PSMA-targeted therapy target patient pool is segmented into:
PSMA-targeted Therapy Report Metrics
Details
Study Period
2020–2034
PSMA-targeted Therapy Report Coverage
7MM [The United States, the EU-4 (Germany, France, Italy, and Spain), the United Kingdom, and Japan]
PSMA-targeted Therapy Target Patient Pool Segmentation
Total Cases in Selected Indications for PSMA-targeted Therapy, Total Eligible Patient Pool in Selected Indications for PSMA-targeted Therapy, and Total Treated Cases in Selected Indications for PSMA-targeted Therapy
Key PSMA-targeted Therapy Companies
Lantheus, Telix Pharmaceuticals, Novartis, and others
Key PSMA-targeted Therapies
Lu-177-PNT2002/[Lu-177]-PSMA-I&T/PNT-2002), 177Lu-DOTA-rosopatamab/TLX591, PLUVICTO, and others
Scope of the PSMA-targeted Therapy Market Report
Discover the latest clinical trial results or Phase III readouts shaping market adoption @ PSMA-targeted Therapy Clinical Trials
Table of Contents
1
PSMA-targeted Therapy Market Key Insights
2
PSMA-targeted Therapy Market Report Introduction
3
Executive Summary of PSMA-targeted Therapy
4
Key Events
5
PSMA-targeted Therapy Market Forecast Methodology
6
PSMA-targeted Therapy Market Overview at a Glance in the 7MM
6.1
PSMA-targeted Therapy Market Share (%) Distribution by Indication in 2024
6.2
PSMA-targeted Therapy Market Share (%) Distribution by Indication in 2034
7
PSMA-targeted therapy: Background and Overview
8
Marketed PSMA-targeted Therapy
8.1
Key Competitors
8.2
PLUVICTO (Lutetium LU-177 Vipivoide Tetraxetan): Novartis
8.2.1
Product Description
8.2.2
Regulatory Milestones
8.2.3
Other Developmental Activities
8.2.4
Clinical Development
8.2.5
Safety and Efficacy
9
Emerging PSMA-targeted Therapies
9.1
Key Competitors
9.2
Lu-177-PNT2002: Lantheus
9.2.1
Product Description
9.2.2
Other Developmental Activities
9.2.3
Clinical Development
9.2.4
Safety and Efficacy
9.3
177Lu-DOTA-rosopatamab tetraxetan (TLX591): Telix Pharmaceutical
10
PSMA-targeted Therapy Market: Seven Major Market Analysis
10.1
Key Findings
10.2
PSMA-targeted Therapy Market Outlook
10.3
Key PSMA-targeted Therapy Market Forecast Assumptions
10.4
Total Market Size of PSMA-targeted Therapy in the 7MM
10.5
The United States PSMA-targeted Therapy Market Size
10.5.1
Market Size by Indications in the United States
10.5.2
Market Size by Therapies in the United States
10.6
EU4 and the UK PSMA-targeted Therapy Market Size
10.7
Japan PSMA-targeted Therapy Market Size
11
PSMA-targeted Therapy Market Access and Reimbursement
12
PSMA-targeted Therapy Market SWOT Analysis
13
KOL Views on PSMA-targeted Therapy
14
PSMA-targeted Therapy Market Unmet Needs
15
Bibliography
16
PSMA-targeted Therapy Market Report Methodology
Related Reports
Prostate Cancer Market
Prostate Cancer Market Insights, Epidemiology, and Market Forecast – 2034 report delivers an in-depth understanding of the disease, historical and forecasted epidemiology, as well as the market trends, market drivers, market barriers, and key prostate cancer companies, including Sanofi, AstraZeneca, Astellas Pharma, Bayer, Novartis, Curium, Merck, Orion, Janssen Pharmaceutical, Pfizer, Exelixis, Ipsen Pharma, Takeda, AB Science, Lantheus, Eli Lilly, POINT Biopharma, Telix Pharmaceuticals, Tavanta Therapeutics, Jiangsu Hengrui Pharmaceuticals, Kangpu Biopharmaceuticals, Fusion Pharma, Merus, Bristol-Myers Squibb, Syntrix Pharmaceuticals, Promontory Therapeutics, Xencor, Taiho Pharmaceutical, Madison Vaccines, MacroGenics, Zenith Epigenetics, Modra Pharmaceuticals, Arvinas, Laekna Therapeutics, Blue Earth Therapeutics, Oncternal Therapeutics, Essa Pharma, Clarity Pharmaceuticals, BioNTech, DualityBio, Daiichi Sankyo, Fortis Therapeutics, ORIC Pharmaceuticals, Amgen, among others.
Metastatic Prostate Cancer Market
Metastatic Prostate Cancer Market Insights, Epidemiology, and Market Forecast – 2034 report delivers an in-depth understanding of the disease, historical and forecasted epidemiology, as well as the market trends, market drivers, market barriers, and key mPC companies including AstraZeneca, Arvinas, Madison Vaccines, Phosplatin Therapeutics, Hinova Pharmaceuticals, MacroGenics, Daiichi Sankyo, AstraZeneca, Seagen, Merck, Bristol Myers Squibb, Taiho Pharmaceutical, Modra Pharmaceuticals, Xencor, Point Biopharma, Lantheus Holdings, Zenith Epigenetics, Essa Pharma, Telix Pharmaceuticals, Kintor Pharmaceutical, AB Science, Eli Lilly and Company, Exelixis, among others.
Metastatic Castration-Sensitive Prostate Cancer Market
Metastatic Castration-Sensitive Prostate Cancer Market Insights, Epidemiology, and Market Forecast – 2034 report delivers an in-depth understanding of the disease, historical and forecasted epidemiology, as well as the market trends, market drivers, market barriers, and key mCSPC companies including Astellas Pharma, Pfizer, Janssen Pharmaceutical, Myovant Sciences, Takeda, Bayer, Merck Sharp & Dohme, Clovis Oncology, Bristol-Myers Squibb, Novartis Pharmaceuticals, Ferring Pharmaceuticals, Genentech, Exelixis, among others.
Metastatic Castration-Resistant Prostate Cancer Market
Metastatic Castration-Resistant Prostate Cancer Market Insights, Epidemiology, and Market Forecast – 2034 report delivers an in-depth understanding of the disease, historical and forecasted epidemiology, as well as the market trends, market drivers, market barriers, and key mCRPC companies including Sanofi, AstraZeneca, Astellas Pharma, Bayer, Novartis, Curium, Merck, Orion, Janssen Pharmaceutical, Pfizer, Exelixis, Ipsen Pharma, Takeda, AB Science, Lantheus, Eli Lilly, POINT Biopharma, Telix Pharmaceuticals, Tavanta Therapeutics, Jiangsu Hengrui Pharmaceuticals, Kangpu Biopharmaceuticals, Fusion Pharma, Merus, Bristol-Myers Squibb, Syntrix Pharmaceuticals, Promontory Therapeutics, Xencor, Taiho Pharmaceutical, Madison Vaccines, MacroGenics, Zenith Epigenetics, Modra Pharmaceuticals, Arvinas, Laekna Therapeutics, Blue Earth Therapeutics, Oncternal Therapeutics, Essa Pharma, Clarity Pharmaceuticals, BioNTech, DualityBio, Daiichi Sankyo, Fortis Therapeutics, ORIC Pharmaceuticals, Amgen, among others.
About DelveInsight
DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences. It supports pharma companies by providing comprehensive end-to-end solutions to improve their performance. Get hassle-free access to all the healthcare and pharma market research reports through our subscription-based platform PharmDelve.
Contact Us
Shruti Thakur
[email protected]
+14699457679
Logo: https://mma.prnewswire.com/media/1082265/3528414/DelveInsight_Logo.jpg
SOURCE DelveInsight Business Research, LLP