Form 8-K

8-K — BioXcel Therapeutics, Inc.

Accession: 0001104659-26-099900

Filed: 2026-08-24

Period: 2026-08-21

CIK: 0001720893

SIC: 2834 (PHARMACEUTICAL PREPARATIONS)

Item: Entry into a Material Definitive Agreement

Item: Financial Statements and Exhibits

Documents

8-K — tm2623861d1_8k.htm (Primary)

EX-10.1 — EXHIBIT 10.1 (tm2623861d1_ex10-1.htm)

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UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 8-K

CURRENT REPORT

Pursuant to Section 13 or 15(d) of

the

Securities Exchange Act of 1934

Date of Report (Date of earliest event reported):

August 21, 2026

BioXcel

Therapeutics, Inc.

(Exact name of registrant as specified in its

charter)

Delaware

001-38410

82-1386754

(State

or other jurisdiction of

incorporation)

(Commission

File Number)

(I.R.S.

Employer

Identification No.)

555

Long Wharf Drive

New

Haven, CT 06511

(Address of principal executive offices, including

Zip Code)

(475)

238-6837

(Registrant’s telephone number, including

area code)

N/A

(Former name or former address, if changed

since last report)

Check

the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under

any of the following provisions:

¨ Written

communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

¨ Soliciting

material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

¨ Pre-commencement

communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

¨ Pre-commencement

communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities registered

pursuant to Section 12(b) of the Act:

Title of each class

Trading Symbol(s)

Name of each exchange on which registered

Common

Stock, par value $0.001

BTAI

The Nasdaq

Capital Market

Indicate

by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405

of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).

Emerging

growth company ¨

an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying

with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ¨

Item 1.01 Entry into a Material Definitive Agreement.

On August 21, 2026, BioXcel Therapeutics, Inc. (the “Company”) entered into the Thirteenth Amendment to Credit Agreement and

Guaranty (the “Thirteenth Amendment”), which amended the Credit Agreement and Guaranty, dated April 19, 2022, as amended (the

“Credit Agreement”), by and among the Company, as the borrower, certain subsidiaries of the Company from time to time party

thereto as subsidiary guarantors, the lenders party thereto (the “Lenders”), and Oaktree Fund Administration LLC, as administrative

agent.

Pursuant to the Thirteenth Amendment, the Company is required to, on or prior to August 28, 2026 (extended from August 21, 2026, as was

required under the Twelfth Amendment), enter into definitive agreements with respect to one or more transactions acceptable to Lenders

that (A) would result in the repayment of all loan and other obligations under the Credit Agreement or (B) is an alternative capital solutions

transaction on terms and conditions acceptable to the Lenders.

The foregoing summary of the Thirteenth Amendment is qualified in its entirety by the complete text of such agreement, a copy of which

is filed hereto as Exhibits 10.1.

Item 9.01 Financial Statements and Exhibits.

(d)   Exhibits.

Ex. No. Description

10.1 Form of Thirteenth Amendment to Credit Agreement and Guaranty, dated August 21, 2026

104 Cover Page Interactive Data File - the cover page XBRL tags are embedded within the Inline XBRL document

SIGNATURES

Pursuant to the requirements

of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto

duly authorized.

Date: August 24, 2026

BIOXCEL THERAPEUTICS, INC.

/s/ Richard Steinhart

By:

Richard Steinhart

Title:

Chief Financial Officer

EX-10.1 — EXHIBIT 10.1

EX-10.1

Filename: tm2623861d1_ex10-1.htm · Sequence: 2

Exhibit 10.1

Reference is made to that certain Credit Agreement and Guaranty,

dated as of April 19, 2022, by and among BioXcel Therapeutics, Inc., the lenders party thereto and Oaktree Fund Administration, LLC, as

administrative agent, as amended, restated, supplemented or otherwise modified from time to time (the “Credit Agreement”).

Capitalized terms used in this email and not otherwise defined herein shall have the meanings assigned to such terms in the Credit Agreement.

Each of the Lenders hereby agree to amend and restate Section

4(a) of the Eleventh Amendment in its entirety as set forth below, effective as of the date hereof:

Transaction Milestone. On or prior to August 28, 2026,

the Obligors shall have entered into definitive agreements with respect to one or more transactions, in form and substance acceptable

to the Majority Lenders in their sole discretion, that (A) would result in the indefeasible payment in full in cash of all Obligations

under the Loan Documents or (B) is an alternative capital solutions transaction on terms and conditions acceptable to the Majority Lenders

in all respects, in their sole and absolute discretion, including, in each case, with respect to the certainty and timing of closing and

the likelihood of obtaining any required shareholder, regulatory, court or other approvals, as applicable (any such transaction, an “Acceptable

Transaction”).

Each of the Lenders hereby agree to amend and restate

Section 4(c) of the Eleventh Amendment in its entirety as set forth below, effective as of the date hereof:

Continued Cooperation. Through and including August

28, 2026, the Obligors shall consider in good faith any reasonable comments by the Lenders or any counterparty to a potential transaction

contemplated by Section 4(a), in each case with respect to any regulatory process involving material assets of the Obligors.

Except as expressly set forth above, (i) all provisions of

the Credit Agreement and the other Loan Documents remain in full force and effect and (ii) the effectiveness of the amendment described

above shall not operate as a waiver of any right, power or remedy of the Administrative Agent or the Lenders, nor constitute a waiver

of any provision of the Credit Agreement or any of the Loan Documents. The agreement to amend the Credit Agreement as set forth

above shall not be deemed to limit or hinder any rights of the Administrative Agent or the Lenders under the Loan Documents, nor shall

it be deemed to create or infer a course of dealing between any such party, on the one hand, and the Borrower, on the other hand, with

regard to any provision of the Loan Documents.

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