Form 8-K
8-K — Liquidia Corp
Accession: 0001104659-26-094411
Filed: 2026-08-12
Period: 2026-08-12
CIK: 0001819576
SIC: 2834 (PHARMACEUTICAL PREPARATIONS)
Item: Results of Operations and Financial Condition
Item: Other Events
Item: Financial Statements and Exhibits
Documents
8-K — tm2622888d1_8k.htm (Primary)
EX-99.1 — EXHIBIT 99.1 (tm2622888d1_ex99-1.htm)
EX-99.2 — EXHIBIT 99.2 (tm2622888d1_ex99-2.htm)
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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 8-K
CURRENT REPORT
Pursuant to Section 13 or 15(d) of the Securities
Exchange Act of 1934
Date of Report (Date of earliest event reported):
August 12, 2026
LIQUIDIA
CORPORATION
(Exact name
of registrant as specified in its charter)
Delaware
001-39724
85-1710962
(State or other jurisdiction
of incorporation)
(Commission
File Number)
(IRS Employer
Identification No.)
419
Davis Drive, Suite
100, Morrisville,
North Carolina
27560
(Address of principal executive
offices)
(Zip Code)
Registrant’s telephone number, including
area code: (919) 328-4400
(Former
name or former address, if changed since last report.)
Check the appropriate box below if the Form 8-K
filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (see
General Instruction A.2. below):
¨
Written communications pursuant to Rule 425 under the Securities Act (17 CFR
230.425)
¨
Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
¨
Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange
Act (17 CFR 240.14d-2(b))
¨
Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange
Act (17 CFR 240.13e-4(c))
Securities registered pursuant to Section 12(b) of the Act:
Title
of each class
Trading
Symbol(s)
Name
of each exchange on which registered
Common
stock
LQDA
The
Nasdaq
Stock Market LLC
Indicate by check mark whether the registrant is
an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the
Securities Exchange Act of 1934 (§240.12b-2 of this chapter).
Emerging
growth company ¨
If
an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying
with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ¨
Item 2.02
Results of Operations and
Financial Condition.
On August 12, 2026, Liquidia Corporation, a Delaware
corporation (the “Company”), issued a press release announcing its financial results for the quarter ended June 30, 2026,
and also provided a corporate update. A copy of the press release is furnished herewith as Exhibit 99.1.*
Item 8.01
Other Events.
On August 12, 2026, the Company updated its corporate
presentation that it uses for presentations at healthcare conferences and to analysts, current stockholders, and others. A copy of the
Company's presentation that it intends to use at such events is filed herewith as Exhibit 99.2 and is incorporated herein by reference.
Item 9.01
Financial Statements and
Exhibits.
(d)
Exhibit
No.
Exhibit
99.1
Press Release of Liquidia Corporation, dated August
12, 2026.
99.2
Liquidia Corporation Corporate Presentation - August
2026.
104
Cover Page Interactive Data File (embedded within the
Inline XBRL document).
* The information in Item 2.02 of this Form 8-K shall not be deemed
“filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), or
otherwise subject to the liabilities of that section, nor shall it be deemed incorporated by reference in any filing under the Securities
Act of 1933, as amended, or the Exchange Act, except as expressly set forth by specific reference in such a filing.
SIGNATURES
Pursuant to the requirements
of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto
duly authorized.
August 12, 2026
Liquidia Corporation
By:
/s/
Michael Kaseta
Name: Michael Kaseta
Title: Chief Financial Officer and Chief Operating
Officer
EX-99.1 — EXHIBIT 99.1
EX-99.1
Filename: tm2622888d1_ex99-1.htm · Sequence: 2
Exhibit 99.1
Liquidia Corporation Reports Second Quarter
2026 Financial Results
· YUTREPIA®
(treprostinil) inhalation powder net product sales of approximately $170.4 million in the
second quarter of 2026, up 31% from the first quarter of 2026
· Approximately 5,900 unique
patient prescriptions and more than 5,000 patients treated between launch in June 2025
and July 31, 2026
· Recorded fourth consecutive
quarter of increasing profitability, with net income of $74.7 million, adjusted EBITDA of
$96.3 million and an increase in cash and cash equivalents of $61.4 million compared to the
first quarter of 2026
· Progressing 10 clinical
studies supporting YUTREPIA and L606 across known and new indications for inhaled treprostinil
MORRISVILLE,
N.C., August 12, 2026 – Liquidia Corporation (NASDAQ: LQDA), a biopharmaceutical company driven by science
and compassion to revolutionize care for patients with challenging respiratory and vascular diseases, today reported financial results
for the second quarter ended June 30, 2026. The company will also host a webcast at 8:30 a.m. ET on August 12, 2026, to
discuss its financial results and provide a corporate update.
Dr. Roger Jeffs, Liquidia’s Chief
Executive Officer, said: “We are pleased by the sustained adoption of YUTREPIA as the inhaled prostacyclin of choice. The inhaled
category has grown almost 40% since launch, and YUTREPIA has captured an ever-increasing share of that growth. We are building on that
momentum by strengthening the clinical evidence for YUTREPIA in PAH and PH-ILD patients transitioning from other therapies, and advancing
studies in new indications that may broaden its impact. Having reset the bar for tolerability and dose flexibility with YUTREPIA, we
are excited to have begun site activation and enrollment in Re-Spire, our pivotal study for L606, which we believe can raise that bar
even further, beyond any therapy currently available or in development.”
YUTREPIA Commercial Launch Highlights
(as of July 31, 2026)
· Received approximately
5,900 unique patient prescriptions since launch in June 2025
· Started more than 5,000
patients on treatment since launch in June 2025
· Prescription-to-start conversion
remained strong above the 85% level as previously reported
· Increased total number
of prescribers to more than 1,100 since launch, of which more than 30% have prescribed YUTREPIA
to at least 5 patients
Second Quarter 2026 Financial Results
YUTREPIA sales led to the company’s fourth consecutive quarter
of increasing profitability with net income of $74.7 million and positive non-GAAP adjusted EBITDA of $96.3 million in the second
quarter of 2026.
Cash and
cash equivalents totaled $284.2 million as of June 30, 2026, compared to $190.7 million as of December 31,
2025.
Product
sales, net, were $170.4 million for the three months ended June 30, 2026, compared to $6.5 million for the three months
ended June 30, 2025. We began shipping YUTREPIA to our customers in the United States in June 2025, following receipt of full
FDA approval for YUTREPIA on May 23, 2025. The increase of $163.9 million was due to higher volume of YUTREPIA sales.
Service
revenue, net, was $1.3 million for the three months ended June 30, 2026, compared to $2.3 million for the three months
ended June 30, 2025. Service revenue, net was related to the promotion agreement with Sandoz, Inc. pursuant
to which we share profits from the sale of Treprostinil Injection in the United States. The decrease of $1.0 million was primarily
due to the impact of unfavorable gross-to-net adjustments.
Cost of
product sales was $10.8 million for the three months ended June 30, 2026, compared to $0.2 million for the three months
ended June 30, 2025. Cost of product sales is related to sales of YUTREPIA. The increase of $10.6 million was primarily due to higher
volume of YUTREPIA sales.
Research
and development expenses were $17.2 million for the three months ended June 30, 2026, compared to $6.0 million for the
three months ended June 30, 2025. The increase of $11.2 million or 185% was primarily due to a $7.0 million increase in expenses
for our L606 program, a $2.0 million increase in expenses related to our YUTREPIA research and development activities, a $0.9 million
increase in personnel expenses driven by higher headcount, and a $1.0 million L606 development milestone recognized during the second
quarter of 2026.
Selling,
general and administrative expenses were $57.4 million for the three months ended June 30, 2026, compared to $38.8 million
for the three months ended June 30, 2025. The increase of $18.6 million or 48% was primarily due to a $10.0 million increase in
personnel expenses and a $3.1 million increase in stock-based compensation driven by higher headcount, and an $8.6 million increase in
commercial and consulting expenses to support the commercialization of YUTREPIA. These increases were partially offset by a $5.5 million
decrease in legal fees related to our ongoing YUTREPIA-related litigation.
Total
other expenses, net was $3.8 million for the three months ended June 30, 2026, compared to $4.1 million for the three
months ended June 30, 2025. The decrease of $0.3 million was primarily attributable to higher money market balances offset by higher
borrowings under our revenue interest financing agreement with HealthCare Royalty Partners IV, L.P.
Income
tax expense was $7.0 million for the three months ended June 30, 2026. We did not recognize any income tax expense during
the three months ended June 30, 2025.
Net income
for the three months ended June 30, 2026, was $74.7 million, or $0.84 per basic and $0.74 per diluted share, as compared
to a net loss of $41.6 million, or $0.49 per basic and diluted share, for the three months ended June 30, 2025.
Webcast Information
Liquidia
will host a live webcast at 8:30 a.m. Eastern Time on August 12, 2026, to discuss the second quarter 2026 financial
results and corporate update. The webcast will be available on Liquidia’s website at https://liquidia.com/investors/events-and-presentations.
A rebroadcast of the event will be available and archived for a period of one year at the same location.
About
YUTREPIA® (treprostinil) Inhalation Powder
YUTREPIA is an inhaled dry-powder formulation of treprostinil delivered
through a convenient, low-effort, palm-sized device. YUTREPIA is indicated for the treatment of PAH and PH-ILD to improve exercise ability.
YUTREPIA was designed using Liquidia’s PRINT® technology, which enables the development of drug particles that are precise
and uniform in size, shape and composition, and that are engineered for enhanced deposition in the lung following oral inhalation. YUTREPIA
was previously referred to as LIQ861 in investigational studies.
About L606 (liposomal treprostinil inhalation suspension)
L606 is an investigational, extended-release
formulation of treprostinil administered twice-daily with a next-generation nebulizer. The L606 suspension uses a proprietary liposomal
formulation to encapsulate treprostinil which can be released slowly at a controlled rate into the lung, enhancing drug exposure over
an extended period of time. L606 is currently being evaluated in an open-label study in the United States for treatment of
PAH and PH-ILD and is the subject of Re-Spire, a global pivotal placebo-controlled efficacy study for the treatment of PH-ILD.
About Treprostinil Injection
Treprostinil Injection is the first-to-file,
fully substitutable generic treprostinil for parenteral administration. Treprostinil Injection contains the same active ingredient, same
strengths, same dosage form and same inactive ingredients as Remodulin® (treprostinil) and is offered to patients and physicians
with the same level of service and support, but at a lower price than the branded drug. Liquidia PAH promotes the appropriate use of
Treprostinil Injection for the treatment of PAH in the United States in partnership with its commercial partner, Sandoz, who holds the
Abbreviated New Drug Application (ANDA) with the FDA.
About
Pulmonary Arterial Hypertension (PAH)
PAH is a rare, chronic, progressive disease
caused by hardening and narrowing of the pulmonary arteries that can lead to right heart failure and eventually death. Currently, an
estimated 45,000 patients are diagnosed and treated in the United States. There is currently no cure for PAH, so the goals
of existing treatments are to alleviate symptoms, maintain or improve functional class, delay disease progression and improve quality
of life.
About
Pulmonary Hypertension Associated with Interstitial Lung Disease (PH-ILD)
PH-ILD includes a diverse collection of up
to 150 different pulmonary diseases, including interstitial pulmonary fibrosis, chronic hypersensitivity pneumonitis, connective tissue
disease-related ILD, and chronic pulmonary fibrosis with emphysema (CPFE) among others. Any level of PH in ILD patients is associated
with poor 3-year survival. A current estimate of PH-ILD prevalence in the United States is greater than 60,000 patients, though
actual prevalence in many of these underlying ILD diseases is not yet known due to factors including underdiagnosis and lack of approved
treatments until March 2021 when inhaled treprostinil was first approved for this indication.
About Liquidia
Corporation
Liquidia Corporation is a biopharmaceutical company driven by science
and compassion to revolutionize care for patients with challenging respiratory and vascular diseases through precise, innovative therapies
and applications of its proprietary PRINT® technology. PRINT enabled the development of YUTREPIA® (treprostinil) inhalation powder
for the treatment of PAH and PH-ILD. The company is also developing L606, an investigational extended-release formulation of treprostinil
administered twice-daily with a next-generation nebulizer, and currently markets generic Treprostinil Injection for the treatment of
PAH. To learn more about Liquidia, please visit www.liquidia.com.
Abbreviations
1. PAH: pulmonary arterial hypertension. 2. PH-ILD: pulmonary hypertension
associated with interstitial lung disease.
Remodulin®
is a registered mark of United Therapeutics Corporation.
Cautionary
Statements Regarding Forward-Looking Statements
This press release may include forward-looking
statements within the meaning of the Private Securities Litigation Reform Act of 1995. All statements contained in this press release
other than statements of historical facts, including statements regarding our future results of operations and financial position, our
strategic and financial initiatives, our business strategy and plans and our objectives for future operations, are forward-looking statements.
Forward-looking statements, including statements
regarding clinical trials, clinical studies and other clinical work (including the funding therefor, anticipated patient enrollment,
safety data, study data, trial outcomes, timing or associated costs), regulatory applications and related submission contents and timelines,
the timelines or outcomes related to patent litigation with United Therapeutics in the U.S. District Court for the District of Delaware
and U.S. District Court for the Middle District of North Carolina, or other litigation between Liquidia and United Therapeutics or others,
including rehearings or appeals of decisions in any such proceedings, the issuance of patents by the USPTO and our ability to execute
on our strategic or financial initiatives, our estimates regarding future expenses, capital requirements and needs for additional financing,
and potential revenue and profitability of YUTREPIA involve significant risks and uncertainties and actual results could differ materially
from those expressed or implied herein. Our ability to maintain YUTREPIA’s approval and to continue commercialization of YUTREPIA
remain subject to ongoing litigation in which United Therapeutics is seeking injunctive relief, which could block our ability to continue
to sell YUTREPIA for one or both of PAH and PH-ILD. The words “anticipate,” “believe,” “continue,”
“could,” “estimate,” “expect,” “intend,” “may,” “plan,” “potential,”
“predict,” “project,” “should,” “target,” “would,” and similar expressions
are intended to identify forward-looking statements. We have based these forward-looking statements largely on our current expectations
and projections about future events and financial trends that we believe may affect our financial condition, results of operations, business
strategy, short-term and long-term business operations and objectives and financial needs. These forward-looking statements are subject
to a number of risks discussed in our filings with the SEC, as well as a number of uncertainties and assumptions. Moreover, we operate
in a very competitive and rapidly changing environment and our industry has inherent risks. New risks emerge from time to time. It is
not possible for our management to predict all risks, nor can we assess the impact of all factors on our business or the extent to which
any factor, or combination of factors, may cause actual results to differ materially from those contained in any forward-looking statements
we may make. In light of these risks, uncertainties and assumptions, the future events discussed in this press release may not occur
and actual results could differ materially and adversely from those anticipated or implied in the forward-looking statements. Nothing
in this press release should be regarded as a representation by any person that these goals will be achieved, and we undertake no duty
to update our goals or to update or alter any forward-looking statements, whether as a result of new information, future events or otherwise.
Use of Non-GAAP Financial Information
This press release and the accompanying tables
include U.S. Generally Accepted Accounting Principles (GAAP) and non-GAAP financial measures. For a description of such non-GAAP financial
measures, including the reasons for using such measures, and reconciliations of such non-GAAP financial measures to the most directly
comparable financial measures prepared in accordance with GAAP, please see the section entitled “About Non-GAAP Financial Information”
below.
Contact Information
Investors:
Jason Adair
Chief Business Officer
919.328.4350
Jason.adair@liquidia.com
Media:
media@liquidia.com
Liquidia Corporation
Select Consolidated Balance Sheet Data
(in thousands)
June 30,
December 31,
2026
2025
Cash and cash equivalents
$ 284,181
$ 190,680
Total assets
$ 521,918
$ 327,934
Total liabilities
$ 326,804
$ 283,186
Accumulated deficit
$ (498,729 )
$ (626,313 )
Total stockholders’ equity
$ 195,114
$ 44,748
Liquidia Corporation
Consolidated Statements of Operations and Comprehensive Income (Loss)
(unaudited)
(in thousands, except share and per share amounts)
Three Months
Ended June 30,
2026
2025
Revenues:
Product sales, net
$ 170,382
$ 6,517
Service revenue,
net
1,297
2,320
Total revenue
171,679
8,837
Costs and expenses:
Cost of product sales
10,759
205
Cost of service revenue
791
1,292
Research and development
17,184
6,021
Selling,
general and administrative
57,428
38,824
Total costs and expenses
86,162
46,342
Income (loss) from operations
85,517
(37,505 )
Other income (expense):
Interest income
2,476
1,584
Interest
expense
(6,296 )
(5,658 )
Total other
expense, net
(3,820 )
(4,074 )
Income (loss) before income taxes
81,697
(41,579 )
Income tax
expense
6,975
—
Net income (loss) and comprehensive
income (loss)
$ 74,722
$ (41,579 )
Net income (loss) per common share,
basic
$ 0.84
$ (0.49 )
Net income (loss) per common share,
diluted
$ 0.74
$ (0.49 )
Weighted average common shares outstanding, basic
88,887,744
85,588,108
Weighted average common shares outstanding, diluted
101,397,028
85,588,108
About Non-GAAP Financial Information
To supplement our financial results presented in accordance with U.S.
Generally Accepted Accounting Principles (GAAP), this press release includes certain non-GAAP financial measures, such as Adjusted EBITDA.
We believe the use of such non-GAAP financial measures provides investors with additional insight into our operational performance. While
we compute non-GAAP financial measures using a consistent method from quarter to quarter and year to year, we may consider whether other
significant items that arise in the future should be excluded from our non-GAAP financial measures.
Adjusted EBITDA is a non-GAAP measure that represents net
income for the period before the impact of interest income, interest expense, other income and expense, income taxes, depreciation and
amortization, and certain items that impact comparison of the performance of our business either period-over-period or with other businesses.
Adjusted EBITDA should not be considered in isolation or as a substitute
to net income or any other measure of financial performance calculated and presented in accordance with GAAP. Our calculation of
Adjusted EBITDA may not be comparable to similarly titled measures of other companies because other companies may not calculate them
in the same manner as we calculate these measures.
For a reconciliation
of such non-GAAP financial measures to the most directly comparable financial measures prepared in accordance with GAAP, please see the
table titled “Reconciliation of Non-GAAP Financial Information” below.
Liquidia Corporation
Reconciliation
of Non-GAAP Financial Information
Reconciliation of Net Income (Loss) to Adjusted EBITDA
(unaudited)
(in thousands)
Three Months Ended
June 30,
2026
Net income
$ 74,722
Interest expense, net
3,820
Income tax expense
6,975
Depreciation and amortization
400
EBITDA
$ 85,917
Stock-based compensation
10,370
Adjusted EBITDA
$ 96,287
EX-99.2 — EXHIBIT 99.2
EX-99.2
Filename: tm2622888d1_ex99-2.htm · Sequence: 3
Exhibit 99.2
©2026 LIQUIDIA CORPORATION ALL RIGHTS RESERVED
Second Quarter 2026 Earnings
& Corporate Update
Liquidia Corporation
August 12, 2026
©2026 LIQUIDIA CORPORATION ALL RIGHTS RESERVED 2
Forward-looking statements
This presentation may include forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. All statements
contained in this presentation other than statements of historical facts, including statements regarding our future results of operations and financial
position, our strategic and financial initiatives, our business strategy and plans and our objectives for future operations, are forward-looking statements.
Forward-looking statements, including statements regarding clinical trials, clinical studies and other clinical work (including the funding therefor,
anticipated patient enrollment, safety data, study data, trial outcomes, timing or associated costs), regulatory applications and related submission
contents and timelines, the timelines or outcomes related to patent litigation with United Therapeutics in the U.S. District Court for the District of
Delaware and U.S. District Court for the Middle District of North Carolina, or other litigation between Liquidia and United Therapeutics or others,
including rehearings or appeals of decisions in any such proceedings, the issuance of patents by the USPTO and our ability to execute on our strategic
or financial initiatives, our estimates regarding future expenses, capital requirements and needs for additional financing, and potential revenue and
profitability of YUTREPIA involve significant risks and uncertainties and actual results could differ materially from those expressed or implied herein. Our
ability to maintain YUTREPIA’s approval and to continue commercialization of YUTREPIA remain subject to ongoing litigation in which United
Therapeutics is seeking injunctive relief, which could block our ability to continue to sell YUTREPIA for one or both of PAH and PH-ILD. The words
“anticipate,” “believe,” “continue,” “could,” “estimate,” “expect,” “intend,” “may,” “plan,” “potential,” “predict,” “project,” “should,” “target,”
“would,” and similar expressions are intended to identify forward-looking statements. We have based these forward-looking statements largely on our
current expectations and projections about future events and financial trends that we believe may affect our financial condition, results of operations,
business strategy, short-term and long-term business operations and objectives and financial needs. These forward-looking statements are subject to a
number of risks discussed in our filings with the SEC, as well as a number of uncertainties and assumptions. Moreover, we operate in a very competitive
and rapidly changing environment and our industry has inherent risks. New risks emerge from time to time. It is not possible for our management to
predict all risks, nor can we assess the impact of all factors on our business or the extent to which any factor, or combination of factors, may cause
actual results to differ materially from those contained in any forward-looking statements we may make. In light of these risks, uncertainties and
assumptions, the future events discussed in this presentation may not occur and actual results could differ materially and adversely from those
anticipated or implied in the forward-looking statements. Nothing in this presentation should be regarded as a representation by any person that
these goals will be achieved, and we undertake no duty to update our goals or to update or alter any forward-looking statements, whether as a result
of new information, future events or otherwise.
©2026 LIQUIDIA CORPORATION ALL RIGHTS RESERVED 3
Use of Non-GAAP Financial Information
To supplement our financial results presented in accordance with U.S. Generally Accepted Accounting Principles (GAAP), this presentation includes
certain non-GAAP financial measures, such as Adjusted EBITDA. We believe the use of such non-GAAP financial measures provides investors with
additional insight into our operational performance. While we compute non-GAAP financial measures using a consistent method from quarter to
quarter and year to year, we may consider whether other significant items that arise in the future should be excluded from our non-GAAP financial
measures.
Adjusted EBITDA is a non-GAAP measure that represents net income for the period before the impact of interest income, interest expense, other
income and expense, income taxes, depreciation and amortization, and certain items that impact comparison of the performance of our business
either period-over-period or with other businesses.
Adjusted EBITDA should not be considered in isolation or as a substitute to net income or any other measure of financial performance calculated and
presented in accordance with GAAP. Our calculation of Adjusted EBITDA may not be comparable to similarly titled measures of other companies
because other companies may not calculate them in the same manner as we calculate these measures.
For a reconciliation of such non-GAAP financial measures to the most directly comparable financial measures prepared in accordance with GAAP,
please see the table titled “Reconciliation of Non-GAAP Financial Information” below.
©2026 LIQUIDIA CORPORATION ALL RIGHTS RESERVED 4
YUTREPIA continues to lead growth of the inhaled prostacyclin market
As of July 31, 2026 900 2,000
2,800
3,600
4,500
5,900
0
550
1,500
2,200
2,900
3,750
5,000
6/3 8/8 10/30 12/31 2/28 4/30 7/31
New Prescriptions
New Patient Starts
% conversion rate
prescription to patient start
for Rx’s remains steady
85%+ More than
5,000
Approx.
5,900
Cut-off dates for patient reporting used in public disclosures
Source: Press Release August 12, 2026, https://liquidia.com/investors/press-releases
~1,100 prescribers
referred patients for YUTREPIA
adding to breadth and depth
~30% of prescribers with 5+ referrals
Launch
©2026 LIQUIDIA CORPORATION ALL RIGHTS RESERVED 5
0.0
26.5
53.0
79.5
106.0
132.5
159.0
185.5
212.0
238.5
265.0
291.5
318.0
344.5
371.0
397.5
424.0
Week 8
n=51
Week 16
n=43
Week 24
n=40
YUTREPIA has raised the bar for inhaled dose range
Data from ASCENT Cohort A (PH-ILD)
*Tyvaso breaths-per-session (bps) comparable dosing is a normalization used to compare dosing across treprostinil products with different delivery frequencies and administration methods. Tyvaso is dosed by inhaled breath, with each breath delivering 6 mcg of treprostinil; total daily exposure is
calculated as breaths per session × sessions per day (4x daily). To enable comparison across products with different dosing regimens (e.g., twice-daily, once-daily), we translate each product's total daily dose into the number of Tyvaso breaths that would deliver a similar exposure. Comparable Tyvaso
bps exposure reflects total daily exposure and is not a measure of breath count, delivery mechanism, or device design across products. Tyvaso® is a registered trademark of United Therapeutics Corporation.; Liquidia data on file
48
45
42
39
36
33
30
27
24
21
18
15
12
9
6
3
0
78%
> 132.5
74%
>132.5
31%
>132.5
median
≈ Comparable
dose to Tyvaso®
bps QID
LIQ861 μg
dose QID
Dose range at Week Visit Change in 6-Minute Walk Distance (6MWD) Simplified Cough Score at Week Visit
Week 8: Sallee S, et al. Poster #1037. PHPN Symposium; 2025; Seattle, WA.; Week 16: Kolaitis NA. Oral presentation. Presented at: CHEST Annual Meeting; 2025; Chicago, Illinois; Week 24: Saggar R, et al. Poster #83. PVRi Annual World Congress; 2026; Dublin, Ireland
Patients quickly titrated above ~15 bps.* Median 𝚫𝚫6MWD continued to increase Cough scores essentially unchanged
median
median +41.0
+31.5
+21.5
0 20 40 60
Week 8
n=49
Week 16
n=41
Meters
Week 24
n=37
Mean
24.3 ± 30.5
Mean
30.2 ± 36.1
Mean
39.6 ± 45.0
1.3 1.3 1.3 1.2 1.4 1.1
0
1
2
3
BL Wk
8
BL Wk
16
BL Wk
24
©2026 LIQUIDIA CORPORATION ALL RIGHTS RESERVED 6
L606 is raising the bar further for inhaled dose range
Data from Ph3 U.S. Open Label (PAH, PH-ILD)
*Tyvaso breaths-per-session (bps) comparable dosing is a normalization used to compare dosing across treprostinil products with different delivery frequencies and administration methods. Tyvaso is dosed by inhaled breath, with each breath delivering 6 mcg of treprostinil; total daily exposure is
calculated as breaths per session × sessions per day (4x daily). To enable comparison across products with different dosing regimens (e.g., twice-daily, once-daily), we translate each product's total daily dose into the number of Tyvaso breaths that would deliver a similar exposure. Comparable Tyvaso
bps exposure reflects total daily exposure and is not a measure of breath count, delivery mechanism, or device design across products. Tyvaso® is a registered trademark of United Therapeutics Corporation.; Liquidia data on file
median
L606 dose range at Week 48 Visit Most common TEAEs (≥10%) thru Week 48* Median change from baseline in 6MWD
Liquidia data on file; 2025.10.29 LQDA RD Day webcast updatedv2.pdf (Oct 28, 2025)
90%+ dosing well above historical target L606 may be most tolerable treprostinil to date Durable response in ∆6MWD at peak & trough
median median
+22.5
+24.3
0 10 20 30 40
Meters
Mean
23.6 ± 57.8
Mean
29.4 ± 64.4
Week 48
n=24
Week 48
n=24
n=28
patients
TEAE* L606 Related
% n % n
Cough 32.1 9 14.3 4
Dyspnea 28.6 8 3.6 1
Fatigue 21.4 6 3.6 1
Dizziness 21.4 6 3.6 1
Nausea 10.7 3 3.6 1
Pruritis 10.7 3 3.6 1
4%
25%
50%
21%
Week 48
n=24
>= 30 bps
~16-29 bps
~9-15 bps
~3-8 bps
210 μg
L606 BID
71%
>210 μg
L606
~14-15 bps QID
comparable
Trough
Peak
Baseline 6MWD for all participants (n=28) = 395.5 m
Trough 6MWD conducted in morning of visit; Peak
6MWD conducted within 90-120 minutes after
administering clinically observed dose
L606 comparable
doses to Tyvaso bps
4x daily*
©2026 LIQUIDIA CORPORATION ALL RIGHTS RESERVED 7
10 studies on-going, recruiting, or initiating within the next year
Pulmonary Arterial Hypertension (PAH), Pulmonary Hypertension associated with Interstitial Lung Disease (PH-ILD), Pulmonary Hypertension associated with Chronic Obstructive Pulmonary Disease (PH-COPD) Systemic Sclerosis-associated Raynaud’s Phenomenon (SSc-RP), Idiopathic Pulmonary Fibrosis (PPF), Progressive Pulmonary Fibrosis (PPF), Pharmacodynamics (PD), Randomized Controlled Trial
(RCT), Dry Powder Inhaler (DPI); Right Ventricle (RV); Tyvaso® and Tyvaso DPI® are registered trademarks of United Therapeutics Corporation
Program Phase II Phase III Phase IV Diseases Name Objective Status
LIQ861*
(treprostinil)
inhalation powder
4x daily, DPI
*FDA approved
LIQ861 to treat PAH
and PH-ILD using
brand name
YUTREPIA® (treprostinil)
inhalation powder
PH-ILD ASCENT
Cohort B Safety & efficacy of transitioning from Tyvaso®, Tyvaso DPI® to YUTREPIA Recruiting
PAH LTI-403 Safety and feasibility of transitioning from oral selexipag to YUTREPIA Initiate Q3’26
PAH SPRINT Hemodynamic study of high doses of YUTREPIA Initiate Q4’26
PAH TRANSITION-PAH
Safety and efficacy of transitioning from IV/SC treprostinil to YUTREPIA
on background sotatercept Initiate 1H’27
PAH TRECOR PD effect on RV hemodynamics by continuous wireless telemetric
pressure monitoring Initiate 1H’27
PH-COPD LTI-306 Safety and efficacy in placebo-controlled RCT Initiate 2H’27
PPF, IPF Safety, efficacy and dose titration Initiate 1H’27
SSc-RP RE-WARM Safety, tolerability and PD in dose-finding study Initiate 4Q’26
L606
treprostinil liposome
inhalation suspension
2x daily, nebulizer
PAH, PH-ILD PBI L606p3 Safety and efficacy in U.S. based study On-going
PH-ILD Re-Spire Safety and efficacy in global, placebo-controlled RCT Recruiting
PAH TRECOR PD effect on RV hemodynamics by continuous wireless telemetric
pressure monitoring Initiate 1H’27
NCT04691154
NCT06129240
NCT07759804
NCT07748000
NCT07285655
©2026 LIQUIDIA CORPORATION ALL RIGHTS RESERVED 8
Exited Q2 2026 at a ~$682M annualized net product sales run-rate
$51.7 $10.1
-$3.5
$157.5
$90.1
$27.3 $14.6
$190.4
$129.9
$71.2
$52.9
$222.8
$170.4
$96.3
$74.7
$284.2
Net Product Sales Adjusted EBITDA* Net Income Cash Balance
$ millions (M)
Q3
2025
Q4
2025
Q1
2026
Q2
2026
*Non-GAAP financial measure. See definition and full reconciliation on slide 10 or in our earnings press release at https://liquidia.com/investors/press-releases.
Growing profitability over last 4 quarters
+31%
Q2/Q1
+35%
Q2/Q1
+$78.2M
in 12 mo.
+$127M
in 12 mo.
©2026 LIQUIDIA CORPORATION ALL RIGHTS RESERVED 9
Second quarter 2026 highlights
LEADING CATEGORY
GROWTH
BROADENING THE
FRANCHISE
SELF-FUNDED
INVESTMENT
$170.4M net product sales 10 studies $96.3M adj. EBITDA*
+31% Q/Q growth in Q2 2026
from Q1 2025
• ~5,900 unique patient
prescriptions through 31-Jul
• More than 1,100 prescribers
• 30% of physicians prescribing
to ≥5 patients through 31-Jul
On-going, recruiting or planned
clinical studies in 2026 & 2027
• Recruiting ASCENT Cohort B
Tyvaso Transitions (PH-ILD)
• Enrolling Phase 3 Re-Spire
globally (PH-ILD)
• Advancing IPF/PPF, PH-COPD,
SSc-Raynaud’s programs
4th consecutive quarter of
Increasing profitability
• $284.2M ending cash
up $61.4M from 1Q’2026
*Non-GAAP financial measure. See definition and full reconciliation on slide 12 or in our earnings press release at https://liquidia.com/investors/press-releases.
©2026 LIQUIDIA CORPORATION ALL RIGHTS RESERVED 10
Scott Moomaw
Chief Commercial Officer
Rajeev Saggar
Chief Medical Officer
Dr. Roger Jeffs
Chief Executive Officer
Michael Kaseta
COO & CFO
Russell Schundler
General Counsel
Q&A session
©2026 LIQUIDIA CORPORATION ALL RIGHTS RESERVED 11
Key financial metrics
Select Consolidated
Statements of Operations
Data Three Months Ended
in thousands 6/30/26 6/30/25
Product sales, net $170,382 $6,517
Service revenue, net 1,297 2,320
Total revenue 171,679 8,837
Cost of product sales 10,759 205
Cost of service revenue 791 1,292
R&D 17,184 6,021
SG&A 57,428 38,824
Total Costs and Expenses 86,162 46,342
Operating Income (Loss) $85,517 $(37,505)
©2026 LIQUIDIA CORPORATION ALL RIGHTS RESERVED 12
Reconciliation of Net Income to Adjusted EBITDA
Three months ended (unaudited, in thousands)
Adjusted EBITDA is a non-GAAP measure. See definition and full reconciliation in our earnings press release at https://liquidia.com/investors/press-releases.
June 30, 2026 Mar 31, 2026 Dec 31, 2025 Sept 30, 2025
Net income $74,722 $52,862 $14,555 $(3,533)
Interest expense, net 3,820 4,722 5,232 5,300
Income tax expense 6,975 3,920 – –
Depreciation &
amortization 400 497 321 476
EBITDA $85,917 $62,001 $20,108 $2,243
Stock-based
compensation 10,370 9,217 7,206 7,899
Adjusted EBITDA $ 96,287 $71,218 $27,314 $10,142
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