Form 8-K

8-K — ArriVent BioPharma, Inc.

Accession: 0001104659-26-115161

Filed: 2026-10-13

Period: 2026-10-12

CIK: 0001868279

SIC: 2834 (PHARMACEUTICAL PREPARATIONS)

Item: Regulation FD Disclosure

Item: Other Events

Item: Financial Statements and Exhibits

Documents

8-K — tm2627450d1_8k.htm (Primary)

EX-99.1 — EXHIBIT 99.1 (tm2627450d1_ex99-1.htm)

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UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 8-K

CURRENT REPORT

Pursuant to Section 13 or 15(d)

of the Securities Exchange Act of 1934

Date of Report (Date of earliest event reported):

October 12, 2026

ARRIVENT

BIOPHARMA, INC.

(Exact name of registrant as specified in its

charter)

Delaware

001-41929

86-3336099

(State

or other jurisdiction

of incorporation)

(Commission

File Number)

(IRS

Employer

Identification No.)

18 Campus Boulevard, Suite 100

Newtown Square, PA

19073

(Address

of principal executive offices)

(zip

code)

Registrant’s telephone number, including

area code: (628) 277-4836

N/A

(Former name or former

address, if changed since last report.)

Check the appropriate box below if the Form 8-K filing is intended

to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

¨ Written communications pursuant to Rule 425 under the Securities

Act (17 CFR 230.425)

¨ Soliciting material pursuant to Rule 14a-12 under the Exchange

Act (17 CFR 240.14a-12)

¨ Pre-commencement communications pursuant to Rule 14d-2(b) under

the Exchange Act (17 CFR 240.14d-2(b))

¨ Pre-commencement communications pursuant to Rule 13e-4(c) under

the Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to Section 12(b) of the Act:

Title

of each class

Trading

Symbol(s)

Name of each exchange

on which registered

Common Stock,

$0.0001 par value per share

AVBP

The

Nasdaq Stock Market LLC

Indicate by check mark whether the registrant is an emerging growth

company as defined in Rule 405 of the Securities Act of 1933 (17 CFR §230.405) or Rule 12b-2 of the Securities Exchange

Act of 1934 (17 CFR §240.12b-2).

Emerging Growth Company x

an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying

with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ¨

Item 7.01      Regulation

FD Disclosure.

On October 12, 2026, ArriVent BioPharma, Inc. (the “Company”)

issued a press release announcing that the Company dosed its first patient in the Phase 1 trial in the U.S. with ARR-002, a potential

first-in-class MUC16/NaPi2b dual-target tetravalent antibody-drug conjugate for ovarian and endometrial cancer. A copy of the press release

is filed as Exhibit 99.1 hereto and is hereby incorporated by reference into this Item 7.01.

The information

in this Item 7.01 is being furnished and shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange

Act of 1934, as amended (the “Exchange Act”), or otherwise subject to the liabilities of that Section, nor shall it be deemed

incorporated by reference into any registration statement or other filing under the Securities Act of 1933, as amended, or the Exchange

Act, except as shall be expressly set forth by specific reference in such filing.

Item 8.01      Other

Events.

The information set forth in the press release referred to in Item

7.01 above, other than the second and third paragraphs thereof, is incorporated by reference into this Item 8.01 of this Current Report

on Form 8-K.

Item 9.01     Financial Statements and Exhibits.

(d) Exhibits.

Exhibit No.

Description

99.1

Press Release dated October 12, 2026.

104

Cover Page Interactive Data File (embedded within the Inline XBRL document).

SIGNATURES

Pursuant to the requirements of the Securities

Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized.

ARRIVENT BIOPHARMA, INC.

By:

/s/ Winston Kung

Winston Kung

Chief Financial Officer and Treasurer

Date: October

13, 2026

EX-99.1 — EXHIBIT 99.1

EX-99.1

Filename: tm2627450d1_ex99-1.htm · Sequence: 2

Exhibit 99.1

ArriVent Announces First Patient Dosed with

Novel Tetravalent MUC16/NaPi2b Dual Target ADC, ARR-002

NEWTOWN SQUARE, PA, October 12, 2026 (GLOBE

NEWSWIRE) -- ArriVent BioPharma, Inc. (Company or ArriVent) (Nasdaq: AVBP), a clinical-stage company dedicated to accelerating the

global development of innovative biopharmaceutical therapeutics, today announced that it dosed its first patient in the Phase 1 trial

in the U.S. with ARR-002 (NCT07755436), a potential first-in-class MUC16/NaPi2b dual-target tetravalent antibody-drug conjugate (ADC)

for ovarian and endometrial cancer.

“We are pleased to have dosed our first

patient with ARR-002, our second ADC from our portfolio to enter the clinic,” said Stuart Lutzker, MD, Ph.D., President of Research

and Development at ArriVent. “Both MUC16 and NaPi2b are highly over-expressed in ovarian and endometrial cancer, and the dual targeting

approach of ARR-002 is designed to overcome a key limitation of single-target ADCs in solid tumors where target expression can be heterogenous

and can limit effective payload delivery to all tumor cells.”

Continues Dr. Lutzker, “The entry

of ARR-002 into the clinic for ovarian and endometrial cancer broadens our clinical pipeline beyond lung and gastrointestinal cancers,

where we also have active programs.”

In August 2026, ArriVent entered into an

exclusive licensing agreement with Shanghai Allist Pharmaceuticals Co., Ltd. to develop and commercialize ARR-002 in Greater China,

which includes mainland China, Hong Kong, Macau and Taiwan, with all other rights retained by ArriVent.

About ArriVent

ArriVent is a clinical-stage biopharmaceutical

company dedicated to the identification, development, and commercialization of differentiated medicines to address the unmet medical needs

of patients with cancers. ArriVent seeks to utilize its team’s deep drug development experience to maximize the potential of its

lead development candidate, firmonertinib, and advance a pipeline of novel therapeutics, such as next-generation antibody drug conjugates,

through approval and commercialization.

About ARR-002

ARR-002 (also known as AV-P138-ADC) is a first-in-class, Mucin-16 (MUC16)

and sodium-dependent phosphate transport protein 2b (NaPi2b) dual-target, tetravalent (2+2 format) ADC, with site-specific conjugation

to vcMMAE at a drug-to-antibody ratio (DAR) of 4. Preclinical data presented at AACR in 2026 (Abstract #2260) demonstrated that ARR-002

has improved in vitro and in vivo activity over bivalent ADCs and that site-specific conjugation of the vcMMAE payload enhances the stability

and safety profile to potentially broaden the therapeutic window in patients. ARR-002 is being studied in a Phase 1 trial to evaluate

the safety, tolerability, efficacy, and pharmacokinetics of ARR-002 in advanced or metastatic ovarian or endometrial cancer (NCT07755436).

Forward-Looking Statements

This press release includes certain disclosures

that contain “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995 about

us and our industry that involve substantial risks and uncertainties. All statements other than statements of historical facts contained

in this press release, including statements regarding our business strategy and plans, activity and safety of ARR-002 compared to available

therapies, anticipated clinical milestones, including the timing of, and results of global development of ARR-002, the expected benefits

of the exclusive license agreement with Allist for ARR-002 in Greater China, and objectives of management for future operations, are forward-looking

statements. In some cases, you can identify forward-looking statements because they contain words such as “anticipate,” “believe,”

“contemplate,” “continue,” “could,” “estimate,” “expect,” “intend,”

“may,” “plan,” “potential,” “predict,” “project,” “should,” “target,”

“will,” or “would” or the negative of these words or other similar terms or expressions. Forward-looking statements

are based on ArriVent’s current expectations and are subject to inherent uncertainties, risks and assumptions that are difficult

to predict. Factors that could cause actual results to differ include, but are not limited to, risks and uncertainties that are described

more fully in the section titled “Risk Factors” in our annual report on Form 10-K for the fiscal year ended December 31,

2025, filed with the Securities and Exchange Commission on March 5, 2026 and our other filings with the Securities and Exchange Commission.

Forward-looking statements contained in this press release are made as of this date, and ArriVent undertakes no duty to update such information

except as required under applicable law.

Contact:

Joyce Allaire

LifeSci Advisors, LLC

jallaire@lifesciadvisors.com

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